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作者： Jun Zhu1;Yingchi Shan1;Yihua Li1;Jiaqi Liu1;Xiang Wu1;Guoyi Gao1;Guoyi Gao2 （1Department of Neurosurgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;2Shanghai Head Trauma Institute, Shanghai, China）
出处： Frontiers in Physiology 2023
关键词： traumatic brain injury;prognosis;intracranial pressure;parameter;spindle wave
摘要： Objective: Intracranial pressure (ICP) monitoring is an integral part of the multimodality monitoring system in the neural intensive care unit. The pr ...
作者： Zeyi Wang;Zhengnan Huang;Xiangqian Cao;Fang Zhang;Jinming Cai;Pengfei Tang;Chenkai Yang;Shengzhou Li;Dong Yu;Yilin Yan;Bing Shen （Department of Urology, Shanghai General Hospital of Nanjing Medical University, Shanghai, 200080, China Department of Urology, Tongji Hospital, School of Medicine, Tongji University, Shanghai, 200065, China Department of Urology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, China Department of Precision Medicine, Center of Translation Medicine, Naval Medical University, Shanghai, 200082, China Department of Urology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, China）
出处： BMC Urology 2023
关键词： Bladder cancer;Necroptosis;Tumor immune microenvironment;Prognostic model;Immunotherapy;Chemotherapy
摘要： Bladder cancer, one of the most prevalent malignant cancers, has high rate of recurrence and metastasis. Owing to genomic instability and high-level h ...
Zhenguo Zi1,2;Shujuan Du3,2;Liming Zhang4,2;Yuebo Wang1;Ling Ding3;Chongqi Zhang1;Huanyu Wang1;Jan Pawlicki5;Yuan Cai6;Yazhou Yao7;Feng Zhou8;Yin Tong9;James L. Riley5;Qiliang Cai3
出处： Blood Advances 2023
关键词： Golgi membrane protein 1 (GOLM1);anaplastic large cell lymphoma (ALCL);anaplastic lymphoma kinase (ALK) ALCL;apoptosis;B-cell lymphoma-extra-large protein (BCL-XL)
摘要： Golgi membrane protein 1 (GOLM1) is aberrantly expressed in many types of solid tumors and contributes to cancer development; however, its role in hem ...
作者： Lin Jin;Mengjiao Zhang;Lei Sha;Mengmeng Cao;Lanyue Tong;Qingqing Chen;Cuiqin Shen;Lianfang Du;Liping Liu;Zhaojun Li （Department of Ultrasound, Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 200052, China Department of Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, 030001, Shanxi, China Department of Medical Imaging, Weifang Medical University, Weifang, 261053, Shandong, China Department of Ultrasound, Shanghai General Hospital Jiading Branch, Shanghai Jiaotong University School of Medicine, Shanghai, 201803, China Department of Ultrasound, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 100 Haining Road, Hongkou District, Shanghai, 200080, China）
出处： BMC Cardiovascular Disorders 2023
关键词： Arterial stiffness;Cardiovascular disease;Arterial pressure volume index;Risk assessment
摘要： Background and objective The new non-invasive arterial stiffness indices, arterial pressure volume index (API) is explored as a novel marker of residu ...
作者： Xuyu Gu1;Lubing Cai2;Zhiwen Luo3;Luze Shi2;Zhen Peng2;Yaying Sun3;Jiwu Chen2 （1School of Medicine, Southeast University, Nanjing, China;2Department of Sports Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, Shanghai, China;3Department of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, China）
出处： Frontiers in Immunology 2023
关键词： lung adenocarcinoma;muscle failure index;ScRNA-seq;prognosis;immunotherapy
摘要： BackgroundIt was previously reported that the production of exerkines is positively associated with the beneficial effects of exercise in lung adenoca ...
作者： Leheng Liu1;Leheng Liu2;Zhixia Dong3;Jinnian Cheng4;Xiongzhu Bu5;Kaili Qiu5;Chuan Yang5;Jing Wang6;Wenlu Niu1;Xiaowan Wu1;Jingxian Xu1;Jingxian Xu2;Tiancheng Mao1;Tiancheng Mao2;Lungen Lu1;Lungen Lu2;Xinjian Wan3;Hui Zhou1;Hui Zhou2 （1Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;2Shanghai Key Laboratory of Pancreatic Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, China;3Department of Gastroenterology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China;4Department of Gastroenterology, Shanghai Tong Ren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;5School of Mechanical Engineering, Nanjing University of Science and Technology, Nanjing, China;6Department of Pathology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China）
出处： Frontiers in Oncology 2023
关键词： deep learning;suspected superficial lesions;magnifying endoscopy with narrow band imaging (ME-NBI);gastric neoplastic lesions;convolutional neural network (CNN)
摘要： BackgroundEndoscopically visible gastric neoplastic lesions (GNLs), including early gastric cancer and intraepithelial neoplasia, should be accurately ...
Nan Li1;Chenxing Huang2;Jie Zhang3;Junyue Zhang1;Jia Huang2;Shangshang Li1;Xue Xia1;Ziyu Wu1;Chenglong Chen1;Shuwan Tang1;Xiangyu Xiao1;Hui Gong2;Yuxiang Dai2
出处： ACS Nano 2023
关键词： ischemia-reperfusion injury;nanomotors;nitric oxide;hydrogen sulfide;targeted delivery
摘要： Recombinant granulocyte colony-stimulating factor (G-CSF), with a direct repair effect on injured cardiomyocytes against myocardial infarction ischemi ...
Zhengzhe Han1;Lili Deng2;Shiyan Chen2
出处： Burns & Trauma 2023
关键词： Hydrogel;Mechanical properties;Biocompatibility;Angiogenic effects;Wound healing
摘要： Background Wound healing is a process that requires angiogenesis and antibacterial activities and it remains a challenge for both experimental and cl ...
作者： Xu Quan1;Ying Xin2;He-Ling Wang3;Yingjie Sun4;Chanchan Chen5;Jiangying Zhang4 （1Department of Stomatology, Shanghai General Hospital, Shanghai, China;2Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi’an Jiaotong University, Xi’an, Shaanxi, China;3Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, Lørenskog, Norway;4Xiangya School of Stomatology, Central South University, Changsha, Hunan, China;5Department of Stomatology, Shenzhen Children’s Hospital, Shenzhen, Guangdong, China）
出处： PeerJ 2023
关键词： Sirtuin;Metabolic regulation;Oral cancer
摘要： Sirtuins (SIRTs 1-7) are a group of histone deacetylase enzymes with a wide range of enzyme activities that target a range of cellular proteins in the ...
作者： Haowei Bai1;Yanwei Sha2;Yueqiu Tan3;Peng Li1;Yuxiang Zhang1;Junwei Xu1;Shuai Xu1;Zhiyong Ji1;Xiaobo Wang1;Wei Chen1;Jianxiong Zhang1;Chencheng Yao1;Zheng Li1;Erlei Zhi1 （1Department of Andrology, Center for Men’s Health, Department of ART, Institute of Urologic Medical Center, Shanghai General Hospital, Shanghai Key Lab of Reproductive Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China;2Department of Andrology, Women and Children’s Hospital, School of Medicine, Xiamen University, Xiamen, Fujian, China;3Institute of Reproductive and Stem Cell Engineering, School of Basic Medical Science, Central South University, Changsha, China）
出处： Frontiers in Endocrinology 2023
关键词： TAF7L;hemizygous variant;oligoasthenoteratozoospermia;ICSI;male infertility
摘要： IntroductionOligoasthenoteratozoospermia (OAT) is a major cause of infertility in males. Only a few pathogenic genes of OAT have been clearly identifi ...