作者： Yannan Jia ^{#  1}, Xinxin Xia ^{#  1}, Jun Yang  ¹, Yu Cai  ¹, Yin Tong  ¹, Huiying Qiu  ¹, Chongmei Huang  ¹, Kun Zhou  ¹, Ying Zhang  ¹, Chang Shen  ¹, Liping Wan  ¹, Xianmin Song  ² （Affiliations ¹ Department of Hematology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of Hematology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. shongxm@sjtu.edu.cn.）

出处： Annals of hematology 2025

关键词： Anti-thymocyte globulin;Graft-versus-host disease;Hematopoietic cell transplantation;Post-transplant cyclophosphamide.

摘要： Our study delved into the clinical outcomes of haploidentical peripheral blood stem cell transplantation (haplo-PBSCT) for older patients, utilizing a ...

作者： Aiqin Zhao ^{#  1}, Sufang Zhou ^{#  2}, Xiaoyi Yang ^{#  3}, Haiying Lu  ¹, Dan Zou  ¹, Xuan Zhang  ¹, Li Liu  ⁴ （Affiliations ¹ The People's Hospital of Suzhou New District, Suzhou, 215129, Jiangsu, China. ² The People's Hospital of Suzhou New District, Suzhou, 215129, Jiangsu, China. zhousuf@sina.com. ³ Department of Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. ⁴ The People's Hospital of Suzhou New District, Suzhou, 215129, Jiangsu, China. 32568353@qq.com.）

出处： Discover oncology 2025

关键词： Immune-related biomarkers;Ovarian cancer;TME;Transcription factor regulation;scRNA-seq.

摘要： Background: Understanding the tumor microenvironment (TME) is essential for the advancement of immunotherapy for ovarian cancer (OC). Nonetheless, pre ...

作者： Peng Lai  ¹, Yichao Ma  ¹, Weilin Sang  ¹, Qiang Zhou  ², Hongjie Chen  ³, Cong Wang  ¹, Jian Yin  ⁴, Tao Wang  ¹, Libo Zhu  ¹, Xiaojun Zhou  ⁵, Chuanglong He  ⁵, Jinzhong Ma  ¹ （Affiliations ¹ Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. ² Department of Otolaryngology, The Third Affiliated Hospital of Wenzhou Medical University (Ruian People's Hospital), Wenzhou 325200, China. ³ The School of Medicine, Nankai University, Tianjin 300071, China. ⁴ Department of Orthopedics, The Affiliated Jiangning Hospital With Nanjing Medical University, Nanjing 211100, China. ⁵ College of Biological Science and Medical Engineering, Donghua University, Shanghai 201620, China.）

出处： ACS applied materials & interfaces 2025

关键词： dimethyl fumarate;liposome;macrophage polarization;osteoarthritis;reactive oxygen species-responsive;targeted delivery.

摘要： The progression of osteoarthritis (OA) is closely linked to synovial inflammation caused by an imbalance between M1 and M2 macrophages. To tackle this ...

作者： Zhaoyang Sheng ^{#  1   2}, Jinshan Xu ^{#  1}, Maoyu Wang ^{#  1}, Xi Xu  ¹, Jinpeng Zhu  ¹, Shuxiong Zeng  ³, Chuanliang Xu  ^{4   5}, Zhensheng Zhang  ⁶ （Affiliations ¹ Department of Urology, Shanghai Changhai Hospital, Naval Medical University, Shanghai, 200433, China. ² Department of Urology, The 904th Hospital, Joint Logistics Support Force, Wuxi, 214000, China. ³ Department of Urology, Shanghai Changhai Hospital, Naval Medical University, Shanghai, 200433, China. zengshuxiong@126.com. ⁴ Department of Urology, Shanghai Changhai Hospital, Naval Medical University, Shanghai, 200433, China. chuanliang_xu@126.comor. ⁵ Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China. chuanliang_xu@126.comor. ⁶ Department of Urology, Shanghai Changhai Hospital, Naval Medical University, Shanghai, 200433, China. 13761178177@163.com.）

出处： BMC cancer 2025

关键词： 16sRNA;BCa;Recurrence;Urinary Microbiome.

摘要： Background: Bladder cancer (BCa) is a common urinary malignancy with high recurrence rates in non-muscle invasive bladder cancer (NMIBC), posing signi ...

作者： Lin-Ping Wang  ¹, Tian-Feng Liu  ¹, Teng-Teng Dai  ², Xin Deng  ³, Lei Tong  ², Qiang-Cheng Zeng  ⁴, Qing He  ⁴, Zhang-Yan Ren  ², Hai-Li Zhang  ⁵, Hai-Sheng Liu  ⁵, Yan-Fang Li  ⁶, Wen-Zhi Li  ⁷, Shuai Zhang  ⁸, Dong-Shu Du  ⁹ （Affiliations ¹ School of Environmental and Chemical Engineering, Shanghai University, Shanghai, China; School of Life Sciences, Shanghai University, Shanghai, China. ² School of Life Sciences, Shanghai University, Shanghai, China. ³ Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Institute of Biomedical Science, Fudan University, Shanghai, China. ⁴ College of Life Sciences, Dezhou University, Dezhou, Shandong, China. ⁵ College of Agriculture and Bioengineering, Heze University, Heze, Shandong, China. ⁶ Department of Preventive Medicine, Heze Medical College, Heze, Shandong, China. ⁷ Department of Urology, School of Medicine, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China. Electronic address: wenchihlee@sina.com. ⁸ International Cooperation Laboratory of Molecular Medicine, Academy of Chinese Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China. Electronic address: szhang@zcmu.edu.cn. ⁹ School of Environmental and Chemical Engineering, Shanghai University, Shanghai, China; School of Life Sciences, Shanghai University, Shanghai, China; College of Life Sciences, Dezhou University, Dezhou, Shandong, China; College of Agriculture and Bioengineering, Heze University, Heze, Shandong, China; Department of Preventive Medicine, Heze Medical College, Heze, Shandong, China; Shaoxing Institute of Shanghai University, Shaoxing, Zhejiang, China. Electronic address: dsdu@shu.edu.cn.）

出处： The Journal of biological chemistry 2025

关键词： Apoptosis;Ferroptosis;Mitochondrial oxidative stress;RVLM;Reactive oxygen species.

摘要： Neuronal hyperexcitability in the rostral ventrolateral medulla (RVLM), driven by oxidative stress, plays a crucial role in stress-induced hypertensio ...

作者： J G Hong  ¹ （Affiliation ¹ Department of Pediatrics, Shanghai General Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.）

出处： Zhonghua er ke za zhi = Chinese journal of pediatrics 2025

摘要： 尽管我国儿童哮喘的诊治水平已有显著提升，但国内关于儿童哮喘的多中心、大样本、对照临床研究仍显不足，尤其是缺乏能够揭示哮喘自然病程及其影响因素的前瞻性队列研究。通过加强多学科合作，开展符合我国儿童哮喘实际情况的临床研究，将有助于进一步提升儿童哮喘的诊治水平，优化治疗方案，推动新疗法的应用，改善患儿的生 ...

作者： Jianli Luan  ¹, Yubin Li  ², Ruipeng Zhang  ³, Yan Gao  ⁴, Heng Zhang  ¹, Jianlie Wu  ¹, Zhenyuan Zhao  ¹, Hongqiao Zhu  ¹, Mingjin Guo  ¹, Junjun Liu  ^{1   5} （Affiliations ¹ Department of Vascular Surgery, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, Shandong, China. ² Department of Vascular Surgery, Linyi Peoples' Hospital, Linyi, Shandong, China. ³ Department of Interventional Vascular Surgery, Qingdao Huang Dao District Central Hospital, Binzhou Medical University, Qingdao, Shandong, China. ⁴ Department of Vascular Surgery, Qingdao Shinan District People's Hospital, Qingdao, Shandong, China. ⁵ Department of Vascular Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 2025

关键词： 2D-digital subtraction angiography;3D-digital subtraction angiography;diagnosis;iliac vein compression syndrome;iliac vein stenosis.

摘要： Purpose: To compare the sensitivity of measuring iliac vein stenosis using two-dimensional digital subtraction angiography (2D-DSA) and three-dimensio ...

作者： Dandan Zhao  ¹, Huimin Li  ², Yongdi Lin  ², Lizhen Liu  ³, Lina Xu  ², Dan Zhang  ⁴, Yu Fu  ², Jiang Hong  ², Congliang Miao  ⁵ （Affiliations ¹ Department of Internal and Emergency Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China; Department of Emergency Medicine, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, China. ² Department of Internal and Emergency Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. ³ Department of Pediatrics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. ⁴ Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201800, China. ⁵ Department of Internal and Emergency Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. Electronic address: mcl15917908206@163.com.）

出处： Heart & lung : the journal of critical care 2025

关键词： B-type natriuretic peptide;Cardiac troponin I;Mortality;Prognostic value;Sepsis.

摘要： Background: Sepsis is a global health challenge with high mortality rates. It demands timely risk identification and biomarker-based strategies to opt ...

作者： Lin-Yi Shen  ¹, Li Sun  ², Wei-Xing Li  ¹, Qian-Ru Li  ¹, Yi-Xin Wen  ³, Yi-Wen Hu  ², Yang Sun  ¹, Ji-Wu Chen  ⁴, Hong-Yun Li  ⁵ （Affiliations ¹ Sports Medicine Institution of Fudan University; Department of Sports Medicine and Arthroscopy Surgery, Huashan Hospital, Fudan University, Shanghai, China, 200040. ² Department of Radiology and Institute of Medical Functional and Molecular Imaging, Huashan Hospital, Fudan University, Shanghai, China, 200040. ³ Department of Orthopedics, Wuhan Fifth Hospital, Jianghan University, Wuhan, China, 430050. ⁴ Department of Sports Medicine, Shanghai General Hospital, Shanghai Jiao Tong University; School of Medicine, Shanghai Jiao Tong University, Shanghai, China, 200080. ⁵ Sports Medicine Institution of Fudan University; Department of Sports Medicine and Arthroscopy Surgery, Huashan Hospital, Fudan University, Shanghai, China, 200040. Electronic address: lieaoon@126.com.）

出处： Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association 2025

摘要： Purpose: To explore the healing status of interportal capsulotomies without repair after arthroscopy in patients with femoroacetabular impingement syn ...

作者： Gayathri Swaminathan  ¹, Yu-Chu Lin  ¹, Jianbo Ni  ², Asna Khalid  ¹, Cheng-Yu Tsai  ¹, Ying Ding  ³, Na Bo  ³, Judy-April Murayi  ⁴, Thottala Jayaraman  ⁵, Ronald Poropatich  ⁶, Rita Bottino  ⁷, Georgios I Papachristou  ⁸, Sunil G Sheth  ⁹, Li Wen  ¹⁰, Monique T Barakat  ¹¹, Adam R Frymoyer  ¹², Mang Yu  ¹³, Sohail Z Husain  ¹⁴ （Affiliations ¹ Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Stanford University, School of Medicine, Stanford, CA, USA. ² Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Stanford University, School of Medicine, Stanford, CA, USA; Department of Gastroenterology and Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ Department of Biostatistics, University of Pittsburgh, Pittsburgh, PA, USA. ⁴ Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Nationwide Children's Hospital, Columbus, OH, USA. ⁵ Department of Oral and Craniofacial Sciences, School of Dental Medicine, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA. ⁶ University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA. ⁷ Imagine Islet Center, Imagine Pharma, 1401 Forbes Avenue, Pittsburgh, PA, USA. ⁸ The Ohio State University Wexner Medical Center, Columbus, OH, USA. ⁹ Beth Israel Deaconess Medical Center, Boston, MA, USA. ¹⁰ Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China. ¹¹ Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Stanford University, School of Medicine, Stanford, CA, USA; Division of Gastroenterology and Hepatology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA. ¹² Division of Neonatology, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA. ¹³ Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Stanford University, School of Medicine, Stanford, CA, USA. Electronic address: myu2045@gmail.com. ¹⁴ Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Stanford University, School of Medicine, Stanford, CA, USA. Electronic address: sohail.husain@stanford.edu.）

出处： Pancreatology : official journal of the International Association of Pancreatology (IAP) ... 2025

关键词： Diclofenac;Pharmacokinetics;Post-ERCP pancreatitis;Rectal.

摘要： Objective: Acute pancreatitis is a frequent, burdensome adverse event of endoscopic retrograde cholangiography (ERCP). Rectal nonsteroidal anti-inflam ...