作者： Li Xu¹;Yihua Xu¹;Yaoxu Jiang²;Jingjing Jiang¹;Shimei Chen¹;Dandan Sun¹;Shenping Li¹;Fang Wei^1,3CA1;Hong Zhu^1,3CA2 （¹Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;²School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China;³National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Disease, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China）

出处： Experimental Eye Research 2024

摘要： Mitochondria-associated ER membranes (MAMs) are contact sites that enable bidirectional communication between the ER (endoplasmic reticulum) and mitoc ...

作者： Guanran Zhang ^{#  1   2   3}, Yanlin Qu ^{#  1   2   3}, Zhenyu Wu  ^{4   5}, Wenjia Liu  ^{1   2   3}, Huihuan Luo  ⁴, Renjie Chen  ⁴, Huixun Jia  ^{1   2   3   4}, Xiaodong Sun  ^{1   2   3} （Affiliations ¹ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai, China. ³ National Clinical Research Center for Eye Diseases, Shanghai, China. ⁴ School of Public Health, Fudan University, Shanghai, China. ⁵ Department of Biostatistics, School of Public Health, Key Laboratory of Public Health Safety and Collaborative Innovation Center of Social Risks Governance in Health, Fudan University, Shanghai, China.）

出处： Journal of global health 2024

摘要： Background: Low lung function is associated with an increased risk of age-related diseases. However, the relationship between age-related macular dege ...

作者： Ren-Guo Xie  ^{1   2} （Affiliations ¹ Department of Hand Surgery, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, 650 New Songjiang Road, Songjiang, Shanghai, 201620, China. 13862906768@163.com. ² Department of Hand Surgery, Affiliated Hospital of Nantong University, 20 West Temple Road, Nantong, Jiangsu, 226001, China. 13862906768@163.com.）

出处： BMC musculoskeletal disorders 2024

关键词： In vivo;Non-contact regions;Scaphoid;Wrist position.

摘要： Introduction: Fractures of the scaphoid are the most common carpal injuries, account for 80-90% of all carpal fractures. 5-15% nonunion of scaphoid fr ...

作者： Di Wang  ¹, Yue Chang  ¹, Weijin Nan  ^{1   2}, Yan Zhang  ^{1   2} （Affiliations ¹ Department of Ophthalmology, The Second Hospital of Jilin University, Changchun, China. ² Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Frontiers in bioengineering and biotechnology 2024

关键词： Scheimpflug;anisometropia;corneal biomechanics;corneal topography;myopia.

摘要： Purpose: This study aims to investigate the differences in binocular corneal parameters and their interrelation with binocular biometric parameters as ...

作者： Man Zhao¹;Luni Zhang²;Jing Chen²;Shiyao Gu²;Rong Wu¹;Caixia Jia² （¹School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China;²Department of Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China）

出处： Ultrasonography 2024

关键词： high-frame-rate vector flow imaging;carotid plaque shape;ischemic stroke;mild carotid stenosis

摘要： Purpose This cross-sectional cohort-comparison observational study investigated the value of high-frame-rate vector flow (V Flow) imaging for evaluati ...

作者： Lingxuan Zhu, MD¹;Weiming Mou, MD²;Peng Luo, MD¹ （¹Department of Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou, China ; ²Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China）

出处： JAMA Internal Medicine 2024

作者： Sihan Du  ¹, Ximin Shen  ², Yi Sun  ², Jia Li  ², Juan Wang  ², Yiting Cai  ³, He Li  ⁴ （Affiliations ¹ Department of Laboratory Medicine, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200080, China; Department of Laboratory Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China. ² Department of Laboratory Medicine, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200080, China. ³ Department of Laboratory Medicine, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200080, China. Electronic address: caiyitingd@qq.com. ⁴ Department of Laboratory Medicine, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200080, China. Electronic address: lihe@bjmu.edu.cn.）

出处： Clinics and research in hepatology and gastroenterology 2024

关键词： Alanine aminotransferase;HBV e antigen;Hepatitis B;PreS1;Viral hepatitis.

摘要： Background and aim: Hepatitis B virus (HBV) infection presents with indicators of varying clinical significance. We aimed to evaluate the correlation ...

作者： Enci Dai  ¹, Wei Wang  ², Yingying Li  ³, Defeng Ye  ⁴, Yanli Li  ⁵ （Affiliations ¹ Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 650 Xinsongjiang Road, Shanghai, 201600, China. Electronic address: daiencixixi@sjtu.edu.cn. ² Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 650 Xinsongjiang Road, Shanghai, 201600, China. Electronic address: wangwei980423@sjtu.edu.cn. ³ Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 650 Xinsongjiang Road, Shanghai, 201600, China. Electronic address: liyingying1119@sjtu.edu.cn. ⁴ Department of Thoracic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 100 Haining Road, Hongkou District, Shanghai, 200080, China. Electronic address: yardphone0326@sjtu.edu.cn. ⁵ Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 650 Xinsongjiang Road, Shanghai, 201600, China. Electronic address: liecho121@126.com.）

出处： Cancer letters 2024

摘要： There is growing evidence that lactate can have a wide range of biological impacts in addition to being a waste product of metabolism. Because of the ...

作者： Wan Sun  ¹, Juan Wang  ², Caiying Liu  ¹, Furong Gao  ¹, Qingjian Ou  ³, Haibin Tian  ¹, Jingying Xu  ¹, Jieping Zhang  ³, Jiao Li  ⁴, Jie Xu  ⁴, Song Jia  ⁴, Jingfa Zhang  ⁵, GuoTong Xu  ⁶, Jian Huang  ⁷, Caixia Jin  ⁸, Lixia Lu  ⁹ （Affiliations ¹ Department of Ophthalmology of Shanghai Tongji Hospital and Laboratory of Clinical Visual Science of Tongji Eye Institute, Tongji University, Shanghai 200065, China; Department of Biochemistry and Molecular Biology, School of Medicine, Tongji University, Shanghai 200065, China. ² Department of Ophthalmology of Shanghai Tongji Hospital and Laboratory of Clinical Visual Science of Tongji Eye Institute, Tongji University, Shanghai 200065, China; Department of Medical Genetics, School of Medicine, Tongji University, Shanghai 200065, China. ³ Department of Ophthalmology of Shanghai Tongji Hospital and Laboratory of Clinical Visual Science of Tongji Eye Institute, Tongji University, Shanghai 200065, China; Department of Pharmacology, School of Medicine, Tongji University, Shanghai 200065, China. ⁴ Department of Biochemistry and Molecular Biology, School of Medicine, Tongji University, Shanghai 200065, China. ⁵ Department of Ophthalmology, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai 200025, China. ⁶ Department of Ophthalmology of Shanghai Tongji Hospital and Laboratory of Clinical Visual Science of Tongji Eye Institute, Tongji University, Shanghai 200065, China; Department of Pharmacology, School of Medicine, Tongji University, Shanghai 200065, China. Electronic address: gtxu@tongji.edu.cn. ⁷ Department of Biochemistry and Molecular Cell Biology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China. Electronic address: jyhuanj@shsmu.edu.cn. ⁸ Department of Ophthalmology of Shanghai Tongji Hospital and Laboratory of Clinical Visual Science of Tongji Eye Institute, Tongji University, Shanghai 200065, China; Department of Biochemistry and Molecular Biology, School of Medicine, Tongji University, Shanghai 200065, China. Electronic address: 12060@tongji.edu.cn. ⁹ Department of Ophthalmology of Shanghai Tongji Hospital and Laboratory of Clinical Visual Science of Tongji Eye Institute, Tongji University, Shanghai 200065, China; Department of Biochemistry and Molecular Biology, School of Medicine, Tongji University, Shanghai 200065, China. Electronic address: lulixia@tongji.edu.cn.）

出处： International journal of biological macromolecules 2024

关键词： Glia maturation factor-β (GMFB);Hyperglycemia;Protein stability;Retinal pigment epithelial cells;SUMOylation.

摘要： Background: Glia maturation factor beta (GMFB) is a growth and differentiation factor that acts as an intracellular regulator of signal transduction p ...

作者： Shuchang Zhang  ¹, Shimei Chen  ¹, Dandan Sun  ¹, Shenping Li  ¹, Jun Sun  ¹, Qing Gu  ¹, Peiyu Liu  ¹, Xiaoqian Wang  ¹, Hong Zhu  ¹, Xun Xu  ¹, Huiming Li  ², Fang Wei  ³ （Affiliations ¹ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, National Clinical Research Center for Eye Diseases, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China. ² Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: li_huiming73@163.com. ³ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, National Clinical Research Center for Eye Diseases, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China. Electronic address: weifang73@hotmail.com.）

出处： Cellular signalling 2024

关键词： Diabetic retinopathy;Mitophagy;Senescence;TIN2;mTOR.

摘要： The telomere-associated protein TIN2 localizes to both telomeres and mitochondria. Nevertheless, the impact of TIN2 on retinal pigment epithelial (RPE ...