作者： Dongjie Chen^{1,2,3 na1};Pengyi Liu^{1,2,3 na1};Xiongxiong Lu^{1,2,3 na1};Jingfeng Li^{1,2,3 na1};Debin Qi^{4 na1};Longjun Zang⁵;Jiayu Lin^1,2,3;Yihao Liu^1,2,3;Shuyu Zhai^1,2,3;Da Fu^1,2,3;Yuanchi Weng^1,2,3;Hongzhe Li ^1,2,3 & …Baiyong Shen^1,2,3 （¹Department of General Surgery, Pancreatic Disease Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China;²Research Institute of Pancreatic Diseases, Shanghai Key Laboratory of Translational Research for Pancreatic Neoplasms, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China;³State Key Laboratory of Oncogenes and Related Genes, Institute of Translational Medicine, Shanghai Jiao Tong University, Shanghai, 200025, China;⁴Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China;⁵Department of General Surgery, Taiyuan Central Hospital, Taiyuan, Shanxi, 030009, China）

出处： Journal of Experimental & Clinical Cancer Research 2024

关键词： Lactate metabolism;Immunotherapy;Survival prognostication;Pan-cancer analysis;scRNA-seq

摘要： Background Immunotherapy has emerged as a potent clinical approach for cancer treatment, but only subsets of cancer patients can benefit from it. Tar ...

作者： Jing Liao¹;Miaomiao Yuan²;Ziqiang Xu³;Youbin Zheng⁴;Zhe Wang⁵;Qitong Huang¹ （¹Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, Key Laboratory of Tissue Engineering of Jiangxi Province, Key Laboratory of Biomedical Sensors of Ganzhou, School of Medical and Information Engineering, School of Pharmacy, Science Research Center, Gannan Medical University, Ganzhou, China;²Precision Research Center for Refractory Diseases in Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;³School of Materials Science and Engineering, Hubei University, Wuhan, China;⁴Department of Electrical Engineering and Electronics, University of Liverpool, Liverpool, United Kingdom;⁵School of Biology and Agricultural Engineering, Jilin University, Changchun, China）

出处： Frontiers in Bioengineering and Biotechnology 2024

关键词： smart nanomaterials;biosensing;nanozyme;cancer therapies;intelligent drug-delivery system;early-diagnosis

作者： Peng Wu ^{#  1}, Yi-Qun Jiang ^{#  2}, Feng-Li Si ^{#  1}, Huan-Ying Wang ^{#  1}, Xiao-Bo Song  ¹, Chun-Feng Sheng  ¹, Xun Xu  ¹, Fan Li  ³, Jing Zhang  ⁴ （Affiliations ¹ Department of Respiratory and Critical Care, Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 201600, China；Songjiang District Central Hospital, Shanghai, 201600, China. ² Department of General Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ Department of Respiratory and Critical Care, Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 201600, China；Songjiang District Central Hospital, Shanghai, 201600, China. lifanking2015@163.com. ⁴ Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China. jingatlas@outlook.com.）

出处： NPJ primary care respiratory medicine 2024

摘要： This study aimed to investigate the real-world standardisation and adherence of medical treatment regimens in patients with chronic obstructive pulmon ...

作者： Kangkang Ou  ¹, Yang Liu  ², Lili Deng  ³, Shiyan Chen  ⁴, Song Gu  ⁵, Baoxiu Wang  ⁶ （Affiliations ¹ School of Textiles and Fashion, Shanghai University of Engineering Science, Shanghai 201620, PR China; State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, PR China. ² School of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai 201620, PR China. ³ State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, PR China. ⁴ State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, PR China. Electronic address: chensy@dhu.edu.cn. ⁵ Trauma Center, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 201620, PR China. Electronic address: song.gu@shgh.cn. ⁶ School of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai 201620, PR China. Electronic address: baoxiu.wang@mail.dhu.edu.cn.）

出处： International journal of biological macromolecules 2024

关键词： Anti-cell adhesion;Antibacterial activity;Bacterial cellulose;Wound dressing.

摘要： Hydrogel-based wound dressings are becoming increasingly important for wound healing. Bacterial cellulose (BC) has been commonly used as wound dressin ...

作者： Fei Shi  ¹, Guiyun Zhang  ¹, Jinshi Li  ², Liang Shu  ³, Cong Yu  ⁴, Dabin Ren  ⁴, Yisong Zhang  ⁴, Ping Zheng  ⁴ （Affiliations ¹ Department of Neurovascular Intervention and Neurosurgery, Shanghai General Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, China. ² Department of Neurology, Shanghai Pudong New area People's Hospital, Shanghai, China. ³ Department of Neurology, Shanghai Ninth People's Hospital, Shanghai, China. ⁴ Department of Neurosurgery, Shanghai Pudong New area People's Hospital, Shanghai, China.）

出处： CNS neuroscience & therapeutics 2024

关键词： LDHB;Mendelian randomization;causal effect;ischemic stroke.

摘要： Aims: Despite the success of single-cell RNA sequencing in identifying cellular heterogeneity in ischemic stroke, clarifying the mechanisms underlying ...

作者： Wei Du  ¹, Ying Li  ¹, Xufeng Wang  ¹, Sunzhe Xie  ¹, Hongfei Ci  ¹, Jiaming Zhou  ¹, Ningqi Zhu  ¹, Zule Chen  ¹, Yan Zheng  ², Huliang Jia  ^{1   3} （Affiliations ¹ Hepatobiliary Surgery, Department of General Surgery, Huashan Hospital, Fudan University, Shanghai, China. ² Department of Pancreatic Surgery, Shanghai General Hospital, Shanghai Key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ Cancer Metastasis Institute, Fudan University, Shanghai, China.）

出处： Cancer science 2024

关键词： ENO2;ceRNA;circESYT2;hepatocellular carcinoma progression;miR‐665.

摘要： Circular RNAs (circRNAs) have emerged as crucial regulators in tumor progression, yet their specific role in hepatocellular carcinoma (HCC) remains la ...

作者： Yang Liu  ¹, Yuanqiong Deng  ², Paul E Constanthin  ³, Fan Li  ¹ （Affiliations ¹ Department of Ultrasound, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. ² Department of Ultrasound, Maternal and Child Health Hospital of Shanghai Jiading District, Shanghai, China. ³ CHU Pellegrin, Service de Neurochirurgie B, Hôpital Pellegrin-Tripode, Place Amélie Raba-Léon, 33 076, Bordeaux Cedex, France.）

出处： Journal of Cancer 2024

关键词： MRI;UTMD;pancreatic cancer;polyethyleneimine nanogels.

摘要： The chemoresistance of pancreatic cancer tumors urgently needs to be addressed. Pancreatic cancer is characterized by an abundant stroma, with signifi ...

作者： Kaiyuan Liu  ¹, Pengfei Zan  ¹, Zihua Li  ², Hengli Lu  ², Peng Liu  ³, Li Zhang  ², Hongsheng Wang  ¹, Xiaojun Ma  ¹, Feng Chen  ⁴, Jing Zhao  ³, Wei Sun  ¹ （Affiliations ¹ Department of Bone Tumor Surgery, Shanghai General Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, 200080, P. R. China. ² School of Medicine, Tongji University, Shanghai, 200072, P. R. China. ³ Scientific Research Center, The Seventh Affiliated Hospital of Sun Yat-sen University, No. 628 Zhenyuan Road, Shenzhen, Guangdong, 518107, China. ⁴ Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Stomatological Hospital and School of Stomatology, Fudan University, Shanghai, P. R. China.）

出处： Advanced healthcare materials 2024

关键词： Osteosarcoma;cGAS‐STING;immunotherapy;mild‐temperature PTT;pyroptosis.

摘要： The immunosuppressive tumor microenvironment (ITME) of osteosarcoma (OS) poses a significant obstacle to the efficacy of existing immunotherapies. Des ...

作者： Chen Ye ^{#  1}, Lin Zhao ^{#  1}, Jiaying Miao ^{#  1}, Chengyu Gong  ², Yuangui Chen  ¹, Shengfei Qin  ³, Nicholas N Tadros  ⁴, Stefan Aufderklamm  ⁵, Wenli Jiang ^{#  2}, Guoying Deng ^{#  6}, Shaoxiong Ming ^{#  1} （Affiliations ¹ Department of Urology, Shanghai Changhai Hospital, Naval Medical University, Shanghai, China. ² Department of Biochemistry and Molecular Biology, College of Basic Medical Sciences, Naval Medical University, Shanghai, China. ³ Department of Urology, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, Shanghai, China. ⁴ Division of Urology, Southern Illinois University, Springfield, IL, USA. ⁵ Department of Urology, Eberhard-Karls University Tübingen, Tübingen, Germany. ⁶ Trauma Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Translational andrology and urology 2024

关键词： Se@SiO2 nanocomposites (Se@SiO2 NPs);antioxidant;hyperoxaluria;kidney stone.

摘要： Background: Nephrolithiasis seriously affects people's health with increasing prevalence and high recurrence rates. However, there is still a lack of ...

作者： Junhao Gu  ¹, Danling Cheng  ¹, Haiyan Li  ², Tao Yu  ¹, Zhenghe Zhang  ¹, Yue Liu  ¹, Xiaoying Wang  ³, Xia Lu  ², Jingchao Li  ¹ （Affiliations ¹ State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai 201620, P. R. China. jcli@dhu.edu.cn. ² Department of Nuclear Medicine, Northern Jiangsu People's Hospital, Clinical Medical College, Yangzhou University, Yangzhou 225001, P. R. China. lxgf2222@163.com. ³ Office of Hospital Infection and Disease Control and Prevention, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, P. R. China. goodwxyz@163.com.）

出处： Journal of materials chemistry. B 2024

摘要： Due to the rapid progression and aggressive metastasis of breast cancer, its diagnosis and treatment remain a great challenge. The simultaneous inhibi ...