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作者: Tiewen Li #  1, Zeng Zhou #  1, Zhiwen Xie #  1, Xuhui Fan  2, Yichen Zhang  1, Yu Zhang  1, Xiaodong Song  1, Yuan Ruan  3 (Affiliations 1 Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Wujin Road 85, Shanghai, 200080, China. 2 Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Wujin Road 85, Shanghai, 200080, China. 3 Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Wujin Road 85, Shanghai, 200080, China. yuanruan@163.com.)

出处: Journal of cancer research and clinical oncology 2023

关键词: Biochemical recurrence;Cancer-associated fibroblast;Immunotherapy;Prostate cancer;Tumor immune microenvironment.

摘要: Background: Cancer-associated fibroblasts (CAFs) are an essential component of the tumor immune microenvironment that are involved in extracellular ma ...

作者: Wei Gong #  1   2, Jingjing Wang #  1, Bo Zhang  1, Xian Xu  2, Haidong Zou  1   2, Kun Liu  2, Xun Xu  1   2, Xiangui He  3   4, Jiannan Huang  5 (Affiliations 1 Department of Clinical Research, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai Vision Health Center & Shanghai Children Myopia Institute, Shanghai, China. 2 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Center of Eye Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China. 3 Department of Clinical Research, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai Vision Health Center & Shanghai Children Myopia Institute, Shanghai, China. xianhezi@163.com. 4 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Center of Eye Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China. xianhezi@163.com. 5 Department of Clinical Research, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai Vision Health Center & Shanghai Children Myopia Institute, Shanghai, China. miller23@126.com.)

出处: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2023

关键词: Astigmatism;Axial length;Children and adolescents;Cylinder power;Myopia.

摘要: Purpose: To describe the association of refraction development and axial length (AL) in young children and provide new insights into the progression o ...

作者: De-Wei An #  1   2   3, Tine W Hansen #  2   4, Lucas S Aparicio  5, Babangida Chori  2   6   7, Qi-Fang Huang  1, Fang-Fei Wei  8, Yi-Bang Cheng  1, Yu-Ling Yu  2   3, Chang-Sheng Sheng  1, Natasza Gilis-Malinowska  9, José Boggia  10, Wiktoria Wojciechowska  11, Teemu J Niiranen  12   13, Valérie Tikhonoff  14, Edoardo Casiglia  14, Krzysztof Narkiewicz  9, Katarzyna Stolarz-Skrzypek  11, Kalina Kawecka-Jaszcz  11, Antti M Jula  12   13, Wen-Yi Yang  15, Angela J Woodiwiss  16, Jan Filipovský  17, Ji-Guang Wang  1, Marek W Rajzer  11, Peter Verhamme  18, Tim S Nawrot  3   6, Jan A Staessen #  19, Yan Li #  1; International Database of Central Arterial Properties for Risk Stratification Investigators‡ (Affiliations 1 Department of Cardiovascular Medicine, Shanghai Key Laboratory of Hypertension, Shanghai Institute of Hypertension, State Key Laboratory of Medical Genomics, National Research Centre for Translational Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, China (D.-W.A., Q.-F.H., Y. B.C., C. S.S., J. G.W., Y.L.). 2 Non-Profit Research Association Alliance for the Promotion of Preventive Medicine, Belgium (D.-W.A, T.W.H, B.C., Y.-L.Y., J.A.S.). 3 Research Unit Environment and Health, Department of Public Health and Primary Care, University of Leuven, Belgium (D.-W.A, Y.-L.Y., T.S.N.). 4 The Steno Diabetes Center Copenhagen, Herlev, and Center for Health, Capital Region of Denmark, Copenhagen (T.W.H.). 5 Servicio de Clínica Médica, Sección Hipertensión Arterial, Hospital Italiano de Buenos Aires, Argentina (L.S.A.). 6 Centre for Environmental Sciences, Hasselt University, Belgium (B.C., T.S.N.). 7 Department of Internal Medicine, Faculty of Clinical Sciences, College of Health Sciences, University of Abuja, Nigeria (B.C.). 8 Department of Cardiology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China (F.-F.W.). 9 Hypertension Unit, Department of Hypertension and Diabetology, Medical University of Gdańsk, Poland (N.G.-M., K.N.). 10 Centro de Nefrología and Departamento de Fisiopatología, Hospital de Clínicas, Universidad de la República, Montevideo, Uruguay (J.B.). 11 First Department of Cardiology, Interventional Electrocardiology and Hypertension, Jagiellonian University Medical College, Kraków, Poland (W.W., K.S.-S., M.R., K.K.-J). 12 Department of Chronic Disease Prevention, Finnish Institute for Health and Welfare, Turku, Finland (T.J.N., A.M.J.). 13 Department of Medicine, Turku University Hospital and University of Turku, Finland (T.J.N., A.M.J.). 14 Department of Medicine, University of Padova, Italy (V.T., E.C.). 15 Department of Cardiology, Shanghai General Hospital, China (W.-Y.Y.). 16 School of Physiology, University of the Witwatersrand, Johannesburg, South Africa (A.W.). 17 Faculty of Medicine, Charles University, Pilsen, Czech Republic (J.F.). 18 Center for Molecular and Vascular Biology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Belgium (P.V.). 19 Biomedical Science Group, Faculty of Medicine, University of Leuven, Belgium (J.A.S.).)

出处: Hypertension (Dallas, Tex. : 1979) 2023

关键词: aortic pulse wave velocity;cardiovascular disease;hypertension;metabolic syndrome;type-2 diabetes.

摘要: Background: Aortic pulse wave velocity (PWV) predicts cardiovascular events (CVEs) and total mortality (TM), but previous studies proposing actionable ...

作者: Yuanyuan Zhang #  1, Tong Ge #  1, Meijuan Huang  1, Yun Qin  2, Tianjiao Liu  3, Wei Mu  1, Gaoxiang Wang  1, Lijun Jiang  1, Tongjuan Li  1, Lei Zhao  1, Jue Wang  1 (Affiliations 1 Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China. 2 Department of Hematology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China. 3 Department of Hematology, Harbin Medical University Cancer Hospital, Harbin, People's Republic of China.)

出处: International journal of nanomedicine 2023

关键词: CD19 antigen;chimeric antigen receptor T-cell;extracellular vesicles;immunotherapy.

摘要: Background: CAR-T cell therapy is effective in the treatment of certain hematological malignancies, and the expansion and functional persistence of CA ...

作者: Yihan Zhang1;Ying Chen2;Ruihua Chen1;Hong Zhou1;Yi Lin1;Bingxin Li1;Huaidong Song3;Guoqiang Zhou4CA1;Mei Dong3CA2;Huanbai Xu1CA31Department of Endocrinology and Metabolism, Center for Microbiota and Immunological Diseases, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China;2Department of Endocrinology and Metabolism, Changhai Hospital of Shanghai, Shanghai, China;3Department of Molecular Diagnostics & Endocrinology, The Core Laboratory in Medical Center of Clinical Research, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;4Department of General Surgery, The Affiliated Changshu Hospital of Xuzhou Medical University, Changshu, China)

出处: BMC Cancer 2023

关键词: m6A RNA methylation regulators;YTHDF3;Thyroid cancer;Biomarkers;Immune infiltration

摘要: Purpose Thyroid cancer (TC) is one of the most common endocrine malignancies, and its morbidity continues to rise. N6-methyladenosine (m

作者: Jian Shen  1, Bimeng Zhang  2, Xiajun Xie  3, Jiajia Lv  4 (Affiliations 1 Department of Pediatrics, Yueyang Hospital of Chinese Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200047, China. Electronic address: shenjian_78@shutcm.edu.cn. 2 Department of Acupuncture and Moxibustion, Shanghai General Hospital, Jiaotong University School of Medicine, Shanghai, 200080, China. Electronic address: pjzhtiger08@aliyun.com. 3 Guangzhong Road Street Community Health Service Center, Hongkou District, Shanghai, China. Electronic address: bluejunjun@163.com. 4 Department of Pediatrics, Yueyang Hospital of Chinese Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200047, China. Electronic address: yoka620@163.com.)

出处: Asian journal of surgery 2023

关键词: Graded treatment;Medical resource sharing;Traditional Chinese medicine.

作者: Keru Gu  1, Shengyi Feng  2, Xinyue Zhang  1, Yuanyuan Peng  1, Peipei Sun  1, Wenchi Liu  1, Yi Wu  1, Yun Yu  1, Xijian Liu  1, Xiaohui Liu  1, Guoying Deng  3, Jun Zheng  4, Bo Li  5, Linjing Zhao  6 (Affiliations 1 College of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai, 201620, China. 2 Center of Traumatology and Orthopedics, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China. 3 Trauma Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China. 4 Center of Traumatology and Orthopedics, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China. Electronic address: dudu8238@163.com. 5 Center of Traumatology and Orthopedics, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China. Electronic address: libo@shutcm.edu.cn. 6 College of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai, 201620, China. Electronic address: ljzhao@sues.edu.cn.)

出处: Journal of ethnopharmacology 2023

关键词: Antifungal activity;Candida albicans;Cinnamomum cassia;Essential oil;Greedy algorithm;Microbial metabolomics;Molecular docking;Network pharmacology.

摘要: Ethnopharmacological relevance: Fungal pathogens can cause deadly invasive infections and have become a major global public health challenge. There is ...

作者: Huiyun Lin  1, Yihui Song  1, Lingjun Song  2, Zilong Geng  1, Runtan Cheng  1, Yinrui Lei  1, Fang Guo  1 (Affiliations 1 Key Laboratory of Systems Biomedicine, Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, 800 Dong chuan Road, Shanghai 200240, China. 2 Pathology Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 100 Hai-Ning Road, Shanghai 200080, China.)

出处: International journal of biological sciences 2023

关键词: H3K9 acetylation;cancer therapy;heat shock;hyperthermia.

摘要: Heat stress, clinically known as hyperthermia, is a promising adjunctive modality in cancer treatment. However, the efficacy of hyperthermia as a mono ...

作者: Shi-Wei Liu  1   2   3, Jia-Qiang Luo  1   3, Liang-Yu Zhao  4, Ning-Jing Ou  1   2   3, Chao-Yang  5, Yu-Xiang Zhang  1   3, Hao-Wei Bai  1   3, Hong-Fang Sun  1   3, Jian-Xiong Zhang  1   3, Chen-Cheng Yao  1   3, Peng Li  1   3, Ru-Hui Tian  1   3, Zheng Li  1   3, Zi-Jue Zhu  1   3 (Affiliations 1 Department of Andrology, Center for Men's Health, Urologic Medical Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. 2 State Key Lab of Reproductive Medicine, Nanjing Medical University, Nanjing 211166, China. 3 Shanghai Key Lab of Reproductive Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. 4 Department of Urology, Guangdong Provincial Key Laboratory of Biomedical Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai 519000, China. 5 Department of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.)

出处: Asian journal of andrology 2023

摘要: The regulation of spermatogonial proliferation and apoptosis is of great significance for maintaining spermatogenesis. The single-cell RNA sequencing ...

作者: Jaafar Abdul-Aziz Mehrez,a  ;Xiyu Chen,a  ;Min Zeng,*a  ;Jianhua Yang, a  ;Nantao Hu, a  ;Tao Wang,a  ;Ruili Liu, a  ;Lin Xu,b  ;Yorexis González-Alfaroc  and ;Zhi Yang *a   (* Corresponding authors a Key Laboratory of Thin Film and Microfabrication (Ministry of Education), Department of Micro/Nano Electronics, School of Electronics Information and Electrical Engineering, Shanghai Jiao Tong University, Shanghai 200240, People's Republic of China E-mail: minzeng@sjtu.edu.cn, zhiyang@sjtu.edu.cn b Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, National Clinical Research Centre for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Centre for Visual Science and Photomedicine, Shanghai 200080, People's Republic of China c Centre for Advanced Studies of Cuba, Havana, Cuba)

出处: Physical Chemistry Chemical Physics 2023

摘要: Vertical van der Waals (vdW) heterostructures have shown potential for gas sensing owing to their remarkable sensitivity. However, the optimization pr ...

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