作者： Min Tang^1,2,3;Xiaohui Wei^1,3;Yunqin Ma^1,3;Yijiong Tan⁴;Han Cao^5,6;Shuangshuang Yao¹;Jiaqi Wang¹;Hua Yang²;Fang Liu¹;Yongde Peng^1,5CA1;Nengguang Fan¹CA2 （¹Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;²Department of Endocrinology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China;³These authors contributed equally to this work.;⁴Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;⁵Department of Endocrinology and Metabolism, Shanghai General Hospital of Nanjing Medical University, Shanghai, China;⁶Department of Endocrinology, Songjiang District Central Hospital, Shanghai, China）

出处： Life Sciences 2025

摘要： Objective The role of ubiquitin-specific protease 13 (USP13) in metabolic dysfunction-associated steatohepatitis (MASH) remains unclear. This study ai ...

作者： Meng Gu  ¹, Jiajun Fang  ², Zhongmei Shao  ³, Hui Yu  ¹, Senchao Guo  ¹, Yang Gao  ¹, Xiaojin He  ⁴, Yuping Xu  ⁵, Mingrong Lv  ⁶ （Affiliations ¹ Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, No 218 Jixi Road, Hefei, Anhui 230022, China; NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract (Anhui Medical University), No 81 Meishan Road, Hefei, Anhui 230032, China; Key Laboratory of Population Health Across Life Cycle (Anhui Medical University), Ministry of Education of the People's Republic of China, No 81 Meishan Road, Hefei, Anhui 230032, China. ² The First Clinical Medical College of Anhui Medical University, Hefei 230032, China. ³ Anhui No. 2 Provincial People's Hospital, Hefei, Anhui 230012, China. ⁴ NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract (Anhui Medical University), No 81 Meishan Road, Hefei, Anhui 230032, China; Reproductive Medicine Center, Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁵ Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, No 218 Jixi Road, Hefei, Anhui 230022, China; NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract (Anhui Medical University), No 81 Meishan Road, Hefei, Anhui 230032, China; Key Laboratory of Population Health Across Life Cycle (Anhui Medical University), Ministry of Education of the People's Republic of China, No 81 Meishan Road, Hefei, Anhui 230032, China. Electronic address: allin0701@126.com. ⁶ Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, No 218 Jixi Road, Hefei, Anhui 230022, China; NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract (Anhui Medical University), No 81 Meishan Road, Hefei, Anhui 230032, China; Key Laboratory of Population Health Across Life Cycle (Anhui Medical University), Ministry of Education of the People's Republic of China, No 81 Meishan Road, Hefei, Anhui 230032, China. Electronic address: lvmingrong2016@163.com.）

出处： Gene 2025

关键词： Assisted reproductive technology;ERCC6;FOXL2;Female infertility;Premature ovarian insufficiency.

摘要： Premature ovarian insufficiency (POI) is the main cause of infertility in women. Some cases of POI are thought to be caused by genetic defects and the ...

作者： Y. Hu^1,2;G. Zhou^3,2;S. Jiang⁴;L. Gao³;Y. Yu⁵;Q. Wang¹;J. Chen¹CA1;J. Zhang⁵CA2 （¹Department of Radiology, Dongtai People's Hospital, Kangfuxi Rd, Yancheng, China;²Dr. Y. Hu and Dr. G. Zhou contributed equally to this study.;³Department of Cardiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;⁴Department of Clinical and Technical Support, Philips Healthcare, China;⁵Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, #85 Wujin Rd, Shanghai, China）

出处： Clinical Radiology 2025

摘要： Aim To analyze epicardial adipose tissue (EAT) radiomics and assess the impact of risk factors on different types of atrial fibrillation (AF). Materia ...

作者： Lingxuan Zhu^1,2;Weiming Mou^1,3;Peng Luo² （¹Authors share first authorship.;²Department of Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou, China;³Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China）

出处： Clinical Gastroenterology and Hepatology 2025

作者： Yu Lv^1,2,3;Xia Wang^1,3;Youjie Zeng⁴;Zizhao Tang^1,5;Fangqin Nie^1,6;Ren Guo¹CA1 （¹Department of Pharmacy, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, China;²Department of Orthopaedics, Shanghai Bone Tumor Institute, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China;³These authors contributed equally to this work.;⁴Department of Anesthesiology, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, China;⁵Department of Pharmacy, The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;⁶Department of Pharmacy, Hospital/School Of Stomatology, Zunyi Medical University, Zunyi, Guizhou 563000, China）

出处： Tissue and Cell 2025

摘要： Introduction The phenotypic transition of vascular smooth muscle cells (VSMCs) from a quiescent, contractile type to a secretory phenotype with high p ...

作者： Bingxin Li  ¹, Xiaoyun Feng  ¹, Yihan Zhang  ¹, Yunhong Huang  ¹, Mingyu Gu  ¹, Haiyan Sun  ¹, Wenqian Ren  ¹, Qin Zhen  ¹, Tingting Shen  ¹, Ling Pan  ¹, Tingting Fan  ¹, Qin Qin  ¹, Fang Liu  ¹, Yongde Peng  ¹, Yufan Wang  ¹, Huanbai Xu  ¹ （Affiliation ¹ Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghais, China.）

出处： Virulence 2025

关键词： COVID-19;COVID-19 vaccines;Hashimoto Thyroiditis;clinical chemistry tests;hypothyroidism;thyroid function tests.

摘要： The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread rapidly, leading to an Omicron outbreak in Shanghai in mid-December after adju ...

作者： Jingjing Li  ¹, Zhicheng Dai  ², Zhengwei Zhang  ³, Chen Chen  ⁴, Xuehui Xiong  ⁵, Falin Xu  ¹ （Affiliations ¹ Department of Neonatal, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China. ² Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ Department of Pathology, Changzheng Hospital, Naval Medical University, Shanghai, China. ⁴ Department of Psychiatry, School of Mental Health and Psychological Sciences, Anhui Medical University, Hefei, China. ⁵ Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Expert opinion on drug safety 2025

关键词： FAERS;adverse events;disproportionate analysis;gabapentinoids;psychiatric disorders.

摘要： Background: Gabapentinoids, including gabapentin and pregabalin, are commonly used for neuropathic pain but have safety concerns. This study analyzed ...

作者： Huihui Wu¹;Liang Zhu²;Xia Geng³;Xiaona Guo³;Tingting Wang³;Jingjing Xu³;Linkai Jiang³;Weibo Zhang⁴CA （¹a Department of Anesthesiology, Shanghai General Hospital, Shanghai, China;²b Rehabilitation Medicine Center, West China Hospital, Sichuan University, Chengdu, China;³c Department of Pain, Dongying People’s Hospital, Dongying, Shandong, China;⁴d Department of Anesthesiology, Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, Hangzhou, China）

出处： Neurological Research 2025

关键词： Chronic constriction injury;inflammation;Schwann cell;miRNA;target

摘要： Objectives Due to the complex and unclear pathogenesis of neuropathic pain, there is a lack of effective therapeutic strategy. miR-363-5p was consider ...

作者： Siguo Feng  ^{1   2}, Qiuyang Zhang  ^{1   2}, Qing Liu  ^{1   2}, Chang Huang  ³, Huiying Zhang  ^{1   2}, Fengsheng Wang  ^{1   2}, Yue Zhu  ^{1   2}, Qizhi Jian  ⁴, Xue Chen  ⁵, Qin Jiang  ^{1   2}, Biao Yan  ⁴ （Affiliations ¹ The Affiliated Eye Hospital, Nanjing Medical University, Nanjing, China. ² The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, China. ³ Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China. ⁴ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁵ Department of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing, China.）

出处： Diabetes 2025

摘要： Diabetic vasculopathy, encompassing complications such as diabetic retinopathy, represents a significant source of morbidity, with inflammation playin ...

作者： Runzhi Huang ^{#  1   2   3}, Jiaying Shi ^{#  4}, Yifan Liu ^{#  5}, Shuyuan Xian ^{#  2   3}, Wei Zhang ^{#  2   3}, Yuntao Yao  ⁵, Xinru Wu  ⁴, Yuanan Li  ⁴, Haoyu Zhang  ⁴, Bingnan Lu  ⁵, Jiajie Zhou  ⁴, Yibin Zhou  ⁴, Min Lin  ⁶, Xiaonan Wang  ⁷, Xin Liu  ⁸, Yue Wang  ⁹, Wenfang Chen  ¹⁰, Chongyou Zhang  ¹¹, Erbin Du  ¹², Qing Lin  ¹³, Zongqiang Huang  ¹⁴, Yu Chen  ¹⁵, Jie Zhang  ¹⁶, Jun Liu  ¹⁷, Xihui Chen  ¹⁸, Xiuwu Pan  ¹⁹, Xingang Cui  ²⁰, Shizhao Ji  ^{21   22}, Huabin Yin  ²³ （Affiliations ¹ Department of Orthopedics, School of Medicine, Shanghai General Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 100 Haining Road, Shanghai, China. ² Department of Burn Surgery, the First Affiliated Hospital of Naval Medical University, Shanghai, People's Republic of China. ³ Research Unit of key techniques for treatment of burns and combined burns and trauma injury, Chinese Academy of Medical Sciences, Shanghai, People's Republic of China. ⁴ Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. ⁵ Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China. ⁶ Mental Health Education and Consultation Center, Chongqing Medical University, 61 Daxuecheng Middle Road, Chongqing, 401331, China. linmin_513@163.com. ⁷ Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing, 100069, China. hnaywxn@163.com. ⁸ Department of Rheumatology and Immunology, Second Affiliated Hospital of Naval Medical University, Shanghai, China. lxsmmu@163.com. ⁹ Department of Health Statistics, School of Public Health, Air Force Medical University, Xi'an, 710032, China. wangyuek11@126.com. ¹⁰ Faculty of Medicine, Jinggangshan University, Ji'An, 343009, China. 9919970039@jgs.edu.cn. ¹¹ Basic Medical College, Harbin Medical University, Heilongjiang, 150081, China. cyzhanghmu@sina.com. ¹² Frist Clinical Medical College, Mudanjiang Medical University, Mudanjiang, 157011, China. 1748855216@qq.com. ¹³ Department of Human Anatomy, Laboratory of Clinical Applied Anatomy, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, 350122, China. linqing522@126.com. ¹⁴ Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. gzhuangzq@163.com. ¹⁵ Department of Gynecology and Obstetrics, The First Affiliated Hospital of Naval Medical University, Yangpu District, No. 168 Changhai Road, Shanghai, 200433, China. yueryw@163.com. ¹⁶ Department of Gynecology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, 201204, China. jiezhang@tongji.edu.cn. ¹⁷ Department of Anesthesiology, Shanghai Pulmonary Hospital Affiliated to Tongji University, 507 Zheng Min Road, Shanghai, 200433, China. yirong007@126.com. ¹⁸ Clinical Education Centre, the, First Affiliated Hospital , PLA Naval Medical University, Shanghai, 200433, China. cxh840808@126.com. ¹⁹ Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China. panxiuwu@126.com. ²⁰ Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China. cuixingang@xinhuamed.com.cn. ²¹ Department of Burn Surgery, the First Affiliated Hospital of Naval Medical University, Shanghai, People's Republic of China. shizhaoji2022@163.com. ²² Research Unit of key techniques for treatment of burns and combined burns and trauma injury, Chinese Academy of Medical Sciences, Shanghai, People's Republic of China. shizhaoji2022@163.com. ²³ Department of Orthopedics, School of Medicine, Shanghai General Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 100 Haining Road, Shanghai, China. yinhuabin@aliyun.com.）

出处： BMC psychology 2025

关键词： Empathy;Jefferson Scale of Empathy (JSE);Learning environment (LE);Medical students.

摘要： Background: Empathy of medical students is crucial, yet it tends to decline as students enter later academic years. Empathy appeared to be affected by ...