作者： Yiwei Wu  ^{1   2}, Ying Xiao  ³, Lipu Cui  ^{1   2}, Xinran Qin  ^{1   2}, Shuli Chen  ^{1   2}, Qingyu An  ^{1   2}, Tianyi Yuan  ^{1   2}, Qiurong Lin  ⁴, Haidong Zou  ^{1   2   4}, Xiangui He  ⁴, Chenhao Yang  ³, Peiyao Jin  ^{1   2} （Affiliations ¹ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² National Clinical Research Centre for Eye Diseases, Shanghai Clinical Research Centre for Eye Diseases, Shanghai Key Clinical Specialty, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Centre for Visual Science and Photomedicine, Shanghai Engineering Centre for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China. ³ Department of Ophthalmology, Children's Hospital of Fudan University, Shanghai, China. ⁴ Shanghai Eye Diseases Prevention and Treatment Centre, Shanghai Eye Hospital, Shanghai, China.）

出处： Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) 2025

关键词： choroidal thickness;diabetic retinopathy;retinal thickness;swept‐source optical coherence tomography;type 1 diabetes mellitus.

摘要： Purpose: To explore the longitudinal changes in retinal and choroidal thickness and their relation with the onset of type 1 diabetes mellitus (T1DM) i ...

作者： Wanjiao Chen  ¹, Jingyi Huang  ¹, Yankun Guo  ², Xinyv Wang  ³, Zhizhe Lin  ³, Ruting Wei  ¹, Jianming Chen  ^{4   5}, Xin Wu  ^{6   7} （Affiliations ¹ Fujian University of Traditional Chinesemedicine, No. 1 Qiuyang Road, Fuzhou, 350122, China. ² Shanghai General Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 85 Wujin Road, Hongkou District, Shanghai, 200080, China. ³ Shanghai Wei Er Lab, Shanghai, 201707, China. ⁴ Fujian University of Traditional Chinesemedicine, No. 1 Qiuyang Road, Fuzhou, 350122, China. chenjm0711@163.com. ⁵ Shanghai Wei Er Lab, Shanghai, 201707, China. chenjm0711@163.com. ⁶ Fujian University of Traditional Chinesemedicine, No. 1 Qiuyang Road, Fuzhou, 350122, China. wuxin007@126.com. ⁷ Shanghai Wei Er Lab, Shanghai, 201707, China. wuxin007@126.com.）

出处： AAPS PharmSciTech 2025

关键词： Composition development;Intravenous nanocrystals;Oncology applications;Preparation process.

摘要： Intravenous routes of drug delivery are widely used in clinical practice due to the advantages of fast onset of action and avoidance of first-pass eff ...

作者： Xue-Lin Wang  ¹, Yu Chen  ², Jin-Yu Hu  ³, Hong Wei  ³, Qian Ling  ³, Liang-Qi He  ³, Cheng Chen  ³, Yi-Xin Wang  ⁴, Yan-Mei Zeng  ³, Xiao-Yu Wang  ³, Qian-Min Ge  ³, Xu Chen  ⁵, Yi Shao  ^{3   6} （Affiliations ¹ Department of Ophthalmology, the First Affiliated Hospital of Jiangxi Medical College, Shangrao Center Hospital, Eye Hospital of Shangrao City, Shangrao 334000, Jiangxi Province, China. ² Department of Traditional Chinese Medicine, the Second Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang 110000, Liaoning Province, China. ³ Department of Ophthalmology, the First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China. ⁴ School of Optometry and Vision Science, Cardiff University, Cardiff, CF24 4HQ, Wales, UK. ⁵ Ophthalmology Centre of Maastricht University, Maastricht 6200MS, Limburg Provincie, the Netherlands. ⁶ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai 200080, China.）

出处： International journal of ophthalmology 2025

关键词： functional MRI;hypertensive retinopathy;neuroimaging;resting state;voxel-mirrored homotopic connectivity.

摘要： Aim: To analyze whether alterations of voxel mirror homology connectivity (VMHC) values, as determined by resting-state functional magnetic resonance ...

作者： Li-Jun Ji  ¹, Jin-Yu Hu  ^{2   3}, Yan-Mei Zeng  ^{2   3}, Qian Ling  ^{2   3}, Jie Zou  ^{2   3}, Cheng Chen  ^{2   3}, Liang-Qi He  ^{2   3}, Xiao-Yu Wang  ^{2   3}, Hong Wei  ^{2   3}, Xu Chen  ⁴, Yi-Xin Wang  ⁵, Yi Shao  ^{3   6}, Yao Yu  ² （Affiliations ¹ Department of Ophthalmology, Dahua Hospital, Shanghai 200237, China. ² Department of Endocrine and Metabolic, the First Affiliated Hospital of Nanchang University, Jiangxi Clinical Research Centre for Endocrine and Metabolic Disease, Jiangxi Branch of National Clinical Research Center for metabolic Disease, Nanchang 330006, Jiangxi Province, China. ³ Department of Ophthalmology, the First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China. ⁴ Ophthalmology Centre of Maastricht University, Maastricht 6200MS, Limburg Provincie, the Netherlands. ⁵ School of optometry and vision science, Cardiff University, Cardiff, CF24 4HQ, Wales, UK. ⁶ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai 200080, China.）

出处： International journal of ophthalmology 2025

关键词： Hospital Anxiety and Depression Scale;brain areas;diabetic vitreous hemorrhage;voxel-based morphometry.

摘要： Aim: To elucidate the neuropathological mechanisms underlying diabetic vitreous hemorrhage (DVH) and its correlation with clinical characteristics. Me ...

作者： Wei-Jin Zhang  ¹, Xun-Pei Xu  ¹, Xin-Hua Song  ², Zhan-Rong Zhang  ¹, Xuan-Rui Zhang  ¹, Biao Yang  ¹, Zheng-Bo Tao  ¹, Zheng Zhang  ^{1   3}, Xu-Hui Zhou  ^{1   4} （Affiliations ¹ Department of Orthopedics, Changzheng Hospital, Second Military Medical University (Naval Medical University), Shanghai 200003, China. ² Department of Pharmacy, Changzheng Hospital, Second Military Medical University (Naval Medical University), Shanghai 200003, China. ³ Department of Orthopedic Rehabilitation, Qingdao Special Servicemen Recuperation Center of People's Liberation Army Navy, Qingdao 266000, Shandong Province, China. ⁴ Translational Research Center of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201600, China. zhouxuhui@smmu.edu.cn.）

出处： World journal of hepatology 2025

关键词： Bone metabolism;Citespace;Liver;Non-alcoholic fatty liver disease;Osteoporosis;VOSviewer.

摘要： Background: The liver exerts profound influence on skeletal health, while osseous tissues reciprocally modulate hepatic function. This bidirectional m ...

作者： Huixun Jia  ¹, Xiaodong Sun  ² （Affiliations ¹ National Clinical Research Center for Eye Diseases, Shanghai 200080, China; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² National Clinical Research Center for Eye Diseases, Shanghai 200080, China; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: xdsun@sjtu.edu.cn.）

出处： Lancet (London, England) 2025

作者： Cheng Peng  ¹, Chaoqun You  ^{1   2}, Shuang Cao  ³, Linfei Cheng  ^{1   4}, Jiaji Ren  ^{1   2}, Jiashi Cao  ^{1   5}, Jing Wang  ¹, Tielong Liu  ¹ （Affiliations ¹ Department of Orthopedics, Changzheng Hospital, Naval Medical University, Shanghai 200003, China. ² Department of Orthopedics, Clinical Medical College, Weifang Medical University, Weifang 261053, Shandong, China. ³ Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200021, China. ⁴ School of Medicine, Anhui University of Science and Technology, Huainan 232001, China. ⁵ Department of Orthopedics, No. 455 Hospital of the Chinese People's Liberation Army, The Navy Medical University, Shanghai 200052, China.）

出处： Analytical cellular pathology (Amsterdam) 2025

关键词： gene expression;immune system phenomena;osteosarcoma;prognosis;tumor microenvironment.

摘要： Osteosarcoma (OS), characterized by a complex tumor microenvironment, poses challenges in treatment, metastasis, and therapy resistance. This study ex ...

作者： M Zhang  ¹, Y L Pan  ¹, W P Bao  ¹ （Affiliation ¹ Department of Respiratory and Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.）

出处： Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 2025

摘要： Assessment of bronchial asthma is essential to optimize management and improve patient outcomes. A personalized, precision medicine approach, guided b ...

作者： Yunhe Song  ¹, Lin Xie  ², Xiaomin Zhu  ², Sujie Fan  ³, Aiguo Lv  ³, Guangxian Tang  ⁴, Hengli Zhang  ⁴, Li Tang  ⁵, Yao Zhang  ⁵, Lan Lu  ⁶, Meichun Xiao  ⁶, Huiping Yuan  ⁷, Wulian Song  ⁷, Minwen Zhou  ⁸, Xiaohuan Zhao  ⁸, Zhixuan Wang  ¹, Fengbin Lin  ¹, Xiaohong Liang  ¹, Yuying Peng  ¹, Yu Chen  ¹, Zhenyu Wang  ⁹, Ling Jin  ¹, Ki Ho Park  ¹⁰, Keith Barton  ¹¹, Weirong Chen  ¹, Ningli Wang  ¹², Ying Han  ¹³, Dennis Lam  ¹⁴, Robert Weinreb  ¹⁵, Tin Aung  ¹⁶, Clement C Tham  ¹⁷, Xiulan Zhang  ¹⁸; PVP study group （Affiliations ¹ State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou 510060, China. ² Department of Ophthalmology, the Third Affiliated Hospital of Chongqing Medical University, Chongqing 401120, China. ³ Handan City Eye Hospital, The Third Hospital of Handan, Handan 056001, China. ⁴ Department of Ophthalmology, Shijiazhuang People's Hospital, Shijiazhuang 050000, Hebei Province, China. ⁵ Department of Ophthalmology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China. ⁶ Department of Ophthalmology, Fujian Medical University Union Hospital, Fuzhou 350001, Fujian Province, China. ⁷ Department of Ophthalmology, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, Heilongjiang Province, China. ⁸ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai 200080, China. ⁹ Dermatology Hospital, Southern Medical University, Guangzhou, China. ¹⁰ Department of Ophthalmology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea. ¹¹ NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust, UCL Institute of Ophthalmology, London, UK. ¹² Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China. ¹³ Department of Ophthalmology, University of California San Francisco, San Francisco, California, USA. ¹⁴ CMER International Eye Research Center, The Chinese University of Hong Kong (Shenzhen), Shenzhen, People's Republic of China. ¹⁵ Hamilton Glaucoma Center, Viterbi Family Department of Ophthalmology, and Shiley Eye Institute, University of California San Diego, La Jolla, CA, USA. ¹⁶ Singapore Eye Research Institute, Singapore National Eye Centre, Singapore. ¹⁷ Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China zhangxl2@mail.sysu.edu.cn clemtham@cuhk.edu.hk. ¹⁸ Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China zhangxl2@mail.sysu.edu.cn clemtham@cuhk.edu.hk.）

出处： The British journal of ophthalmology 2025

关键词： Glaucoma;Treatment Surgery;Wound healing.

摘要： Purpose: To report the 2-year effective and safety profile of integrated phacoemulsification with intraocular lens implantation (PEI), goniosynechialy ...

作者： Dandan Zhao  ¹, Huimin Li  ², Yongdi Lin  ², Lizhen Liu  ³, Lina Xu  ², Dan Zhang  ⁴, Yu Fu  ², Jiang Hong  ², Congliang Miao  ⁵ （Affiliations ¹ Department of Internal and Emergency Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China; Department of Emergency Medicine, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, China. ² Department of Internal and Emergency Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. ³ Department of Pediatrics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. ⁴ Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201800, China. ⁵ Department of Internal and Emergency Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. Electronic address: mcl15917908206@163.com.）

出处： Heart & lung : the journal of critical care 2025

关键词： B-type natriuretic peptide;Cardiac troponin I;Mortality;Prognostic value;Sepsis.

摘要： Background: Sepsis is a global health challenge with high mortality rates. It demands timely risk identification and biomarker-based strategies to opt ...