作者： Yanzheng Chen  ¹, Xueliang Zhang  ¹, Qing Wang  ², Chang Du  ^{3   4}, Chang-Ming Dong  ¹ （Affiliations ¹ School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240, P. R. China. cmdong@sjtu.edu.cn. ² Department of Stomatology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 200080, P. R. China. ³ Clinical Cancer Institute, Center for Translational Medicine, Naval Military Medical University, Shanghai, 200433, P. R. China. cdu@shsci.org. ⁴ State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200240, P. R. China.）

出处： Biomaterials science 2024

摘要： Regulating the wound microenvironment to promote proliferation, vascularization, and wound healing is challenging for hemostats and wound dressings. H ...

作者： Lijuan Huang^1,2;Xueqing Bai²;Yan Xie²;Yunyu Zhou²;Jin Wu²;Ningdong Li^1,2,3CA1 （¹Department of Ophthalmology, The Second Affiliated Hospital of Fujian Medical University, 362000, Quanzhou, China;²Department of Ophthalmology, Beijing Children’s Hospital, Capital Medical University, 100045, Beijing, China;³Department of Ophthalmology, Shanghai General Hospital, 200940, Shanghai, China）

出处： Orphanet Journal of Rare Diseases 2024

关键词： Congenital stationary night blindness;Myopia;Strabismus;Mutation

摘要： Background Congenital stationary night blindness (CSNB) is an inherited retinal disorder. Most of patients have myopia. This study aims to describe t ...

作者： Changling Duan^1,2;Zhongxin Yan^1,2;Cailiang Wu²;Xuexin Zhou²;Wei Bao²CA1 （¹Contributed equally.;²Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 200080, Shanghai, China）

出处： Heliyon 2024

关键词： Methylation;Chemotherapy resistance;Ovarian cancer;DDR2;OPCML

摘要： Objective The high mortality rate of epithelial ovarian cancer (EOC) is often attributed to the frequent development of chemoresistance. DNA methylati ...

作者： Sibei Tang¹;Junxun Zhang²;Fangzhou Lou¹;Hong Zhou¹;Xiaojie Cai¹;Zhikai Wang²;Libo Sun¹;Yang Sun¹;Xiangxiao Li¹;Li Fan¹;Yan Li¹;Xinping Jin²;Siyu Deng¹;Qianqian Yin²;Jing Bai¹;Hong Wang²;Honglin Wang¹CA1 （¹Precision Research Center for Refractory Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 201610, Shanghai, China;²Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, 200025, Shanghai, China）

出处： EMBO Reports 2024

关键词： LncRNA Encoded Micropeptide;Autoimmunity;Treg Cell;Dleu2;Smad3

摘要： Micropeptides encoded by short open reading frames (sORFs) within long noncoding RNAs (lncRNAs) are beginning to be discovered and characterized as re ...

作者： Yong Zhu ^{#  1}, Xiaoxiao Meng ^{#  1}, Xian Zhu ^{#  1}, Jiaxiang Zhang  ¹, Hui Lv  ¹, Feiyao Wang  ¹, Jinfeng Wang  ¹, Cheng Chen  ¹, Mengting Chen  ¹, Dapeng Wang  ², Wei Jin  ³, Rui Tian  ⁴, Ruilan Wang  ⁵ （Affiliations ¹ Department of Critical Care Medicine, School of Medicine, Shanghai General Hospital, Shanghai Jiaotong University, 650 Xinsongjiang Road, Shanghai, 201620, China. ² Department of Intensive Care Medicine, Wuxi People's Hospital, Nanjing Medical University, Wuxi, 214021, Jiangsu, China. ³ Department of Critical Care Medicine, School of Medicine, Shanghai General Hospital, Shanghai Jiaotong University, 650 Xinsongjiang Road, Shanghai, 201620, China. jw1230123@126.com. ⁴ Department of Critical Care Medicine, School of Medicine, Shanghai General Hospital, Shanghai Jiaotong University, 650 Xinsongjiang Road, Shanghai, 201620, China. thunder021@hotmail.com. ⁵ Department of Critical Care Medicine, School of Medicine, Shanghai General Hospital, Shanghai Jiaotong University, 650 Xinsongjiang Road, Shanghai, 201620, China. wangyusun@hotmail.com.）

出处： Archives of toxicology 2024

关键词： CDK8;Circular RNA MKLN1;Epithelial-mesenchymal transition;Pulmonary fibrosis;miR-26a/b.

摘要： Pulmonary fibrosis involves destruction of the lung parenchyma and extracellular matrix deposition. Effective treatments for pulmonary fibrosis are la ...

作者： Jiuliang Yan ^{#  1}, Xiaofeng Wang ^{#  2}, Zongyu Fan ^{#  3}, Yiqing Xu  ⁴, Yingzi Zhang  ⁴, Yi Liu  ⁴, Lei Guo  ⁵, Dongli Liu  ⁶ （Affiliations ¹ Department of Pancreatic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. ² Department of Medical Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. ³ Department of Oral and Maxillofacial-Head and Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China. ⁴ Department of Radiation Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No.85, Wujin Road, Hongkou District, Shanghai, 200080, China. ⁵ Department of Liver Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Fudan University, Shanghai, 200032, China. guo.lei@zs-hospital.sh.cn. ⁶ Department of Radiation Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No.85, Wujin Road, Hongkou District, Shanghai, 200080, China. loveliudongli@163.com.）

出处： Apoptosis : an international journal on programmed cell death 2024

关键词： Circ_0098823;DNM1L;ERBB3;Hepatocellular carcinoma;IGF2BP3;Mitochondrial fission.

摘要： Hepatocellular carcinoma (HCC) is highly metastatic and invasive. CircRNA participates in gene regulation of multiple tumor metastases, but little is ...

作者： Tung-Liang Hsia  ^{1   2   3   4   5   6   7}, Zhikai Lin  ^{1   2   3   4   5   6}, Yiru Xia  ^{1   2   3   4   5   6}, Rong Shu  ^{1   2   3   4   5   6}, Yufeng Xie  ^{1   2   3   4   5   6   8   9} （Affiliations ¹ Department of Periodontology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² College of Stomatology, Shanghai Jiao Tong University, Shanghai, China. ³ National Center for Stomatology, Shanghai, China. ⁴ National Clinical Research Center for Oral Diseases, Shanghai, China. ⁵ Shanghai Key Laboratory of Stomatology, Shanghai, China. ⁶ Shanghai Research Institute of Stomatology, Shanghai, China. ⁷ Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁸ Department of Periodontology, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, China. ⁹ Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Shanghai, China.）

出处： Journal of periodontal research 2024

关键词： hyaluronic acid;hydrogels;periodontal regeneration;recombinant human amelogenin.

摘要： Objectives: In order to evaluate the effect of methacrylated hyaluronic acid (HAMA) hydrogels containing the recombinant human amelogenin (rhAm) in vi ...

作者： Zi-mei Liu¹;Ying Yuan¹;Lei Jin^2,3CA1 （¹Department of Oncology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, 200336, Shanghai, China;²Department of Rheumatology and Immunology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, 200336, Shanghai, China;³Department of Rheumatology, Immunology & Allergy, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 200080, Shanghai, China）

出处： Discover Oncology 2024

关键词： Anlotinib;Synovial Sarcoma;FAM83D;Proliferation;Apoptosis

摘要： Objective Synovial Sarcoma (SS), a highly malignant mesenchymal neoplasm, typically carries a grim prognosis for patients presenting with high-grade ...

作者： Yun Bai¹;Zi-Chen An¹;Fan Li¹;Lian-Fang Du¹;Tian-Wu Xie²CA1;Xi-Peng Zhang³CA2;Ying-Yu Cai¹CA3 （¹Department of Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 85/86 Wujin Road, 200080, Shanghai, China;²Institute of Radiation Medicine, Fudan University, No. 2094 Xietu Road, 200032, Shanghai, China;³School of Computer Science and Technology, Taiyuan Normal University, No. 319 Daxue Street, 030619, Taiyuan, China）

出处： World Journal of Urology 2024

关键词： Kidney neoplasms;Artificial intelligence;Deep learning;Nuclear grade;Classification;Contrast-enhanced ultrasound

摘要： Purpose To assess the effectiveness of a deep learning model using contrastenhanced ultrasound (CEUS) images in distinguishing between low-grade (gra ...

作者： Peiyao Jiang  ¹, Fangfang Yu  ¹, Xiao Zhou  ¹, Huizhong Shi  ¹, Qiaomei He  ², Xianmin Song  ³ （Affiliations ¹ Shanghai General hospital,Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of Hematology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, China. ³ Department of Hematology, Shanghai General hospital,Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Blood advances 2024

摘要： Causal relationships between gut microbiota, inflammatory cytokines and diffuse large B-cell lymphoma (DLBCL) remain elusive. In addressing this gap, ...