作者： Guobin Qi  ¹, Xianglong Liu  ^{1   2}, Leilei Shi  ³, Jiahao Zhuang  ¹, Bin Liu  ^{1   2   4} （Affiliations ¹ Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore, 117585, Singapore. ² Joint School of National University of Singapore and Tianjin University, International Campus of Tianjin University, Binhai New City, Fuzhou, 350207, China. ³ Precision Research Center for Refractory Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201600, China. ⁴ Institute for Functional Intelligent Materials, National University of Singapore, Blk S9, Level 9, 4 Science Drive 2, Singapore, 117544, Singapore.）

出处： Advanced materials (Deerfield Beach, Fla.) 2023

关键词： ATRP;bacteria-templated polymer;bacterial infection;target depletion.

摘要： Selective and targeted removal of individual species or strains of bacteria from complex communities can be desirable over traditional and broadly act ...

作者： Bingqiong Wang  ¹, Jialing Zhou  ¹, Xiaoning Wu  ¹, Yameng Sun  ¹, Lei Li  ^{2   3}, Ping Li  ⁴, Minghui Li  ⁵, Wei Jiang  ⁶, Mingyi Xu  ^{7   8}, Bo Feng  ⁹, Xiaoyuan Xu  ¹⁰, Jilin Cheng  ¹¹, Wen Xie  ⁵, Tao Han  ^{12   13}, Xiaozhong Wang  ¹⁴, Hai Li  ¹⁵, Hongxin Piao  ¹⁶, Xinyu Zhao  ¹⁷, Shuyan Chen  ¹, Tongtong Meng  ¹, Qiushuang Guan  ¹, Fandong Meng  ¹⁸, Yuanyuan Kong  ¹⁷, Xiaojuan Ou  ¹, Jidong Jia  ¹, Hong You  ¹ （Affiliations ¹ Liver Research Center, Beijing Friendship Hospital, Capital Medical University, Beijing Key Laboratory of Translational Medicine on Liver Cirrhosis, National Clinical Research Center for Digestive Diseases, Beijing, China. ² Department of Gastroenterology and Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing, China. ³ Department of Gastroenterology and Hepatology, Beijing Jishuitan Hospital, Beijing, China. ⁴ Department of Hepatology, Tianjin Second People's Hospital, Tianjin, China. ⁵ Liver Disease Center, Beijing Ditan Hospital, Capital Medical University, Beijing, China. ⁶ Department of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai, China. ⁷ Department of Gastroenterology and Hepatology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁸ Department of Gastroenterology and Hepatology, Shanghai Dongfang Hospital, Shanghai, China. ⁹ Hepatology Institute, Peking University People's Hospital, Beijing, China. ¹⁰ Department of Infectious Disease, Peking University First Hospital, Beijing, China. ¹¹ Department of Gastroenterology, Shanghai Public Health Clinical Center, Shanghai, China. ¹² Department of Hepatology, Tianjin Third Central Hospital, Tianjin Medical University, Tianjin, China. ¹³ Department of Gastroenterology and Hepatology, Tianjin Union Medical Center Affiliated to Nankai University, Tianjin, China. ¹⁴ Department of Hepatology, Xinjiang Uygur Autonomous Region Traditional Chinese Medicine Hospital, Urumqi, Xinjiang, China. ¹⁵ Department of Gastroenterology, Tianjin Xiqing Hospital, Tianjin, China. ¹⁶ Department of Infectious Diseases, Affiliated Hospital of Yanbian University, Yanji, China. ¹⁷ Department of Clinical Epidemiology and EBM Unit, National Clinical Research Center for Digestive Diseases, Beijing, China; Beijing Friendship Hospital, Capital Medical University. ¹⁸ Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Diseases, Beijing, China.）

出处： The American journal of gastroenterology 2023

摘要： Objectives: Portal hypertension progression can be relieved after controlling the etiology of liver cirrhosis. Whether beta-blockers could additionall ...

作者： Yu-Ling Yu  ^{1   2}, De-Wei An  ^{1   2   3}, Wen-Yi Yang  ⁴, Peter Verhamme  ⁵, Karel Allegaert  ^{6   7   8}, Tim S Nawrot  ^{1   9}, Jan A Staessen  ^{2   10} （Affiliations ¹ Research Unit Environment and Health, KU Leuven Department of Public Health and Primary Care, University of Leuven, Leuven, Belgium. ² Non-Profit Research Association Alliance for the Promotion of Preventive Medicine, Mechelen, Belgium. ³ Department of Cardiovascular Medicine, Shanghai Key Laboratory of Hypertension, Shanghai Institute of Hypertension, State Key Laboratory of Medical Genomics, National Research Centre for Translational Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. ⁴ Department of Cardiology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. ⁵ Center for Molecular and Vascular Biology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium. ⁶ Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium. ⁷ KU Leuven Department of Development and Regeneration, KU Leuven, Leuven, Belgium. ⁸ Department of Hospital Pharmacy, Erasmus Medical Center, Rotterdam, The Netherlands. ⁹ Center for Environmental Sciences, Hasselt University, Diepenbeek, Belgium. ¹⁰ Biomedical Science Group, Faculty of Medicine, University of Leuven, Leuven, Belgium.）

出处： Journal of clinical hypertension (Greenwich, Conn.) 2023

关键词： blood pressure;hypertension;lead;occupational exposure;renal function.

摘要： The Study for Promotion of Health in Recycling Lead (SPHERL) assessed the blood pressure (BP) and renal function (RF) responses for up to 6 years in t ...

作者： Yuxi Zhao  ¹;Zhaoxiang Zeng  ²;Xianhao Bao  ¹;Mingwei Wu  ³;Jiaxuan Feng  ²;Zaiping Jing  ²;Rui Feng  ⁴ （Affiliations ¹ Department of Vascular Surgery, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, China. ² Department of Vascular Surgery, Changhai Hospital, Navy Medical University, Shanghai, China. ³ Department of Vascular and Endovascular Surgery, Chinese PLA General Hospital, Beijing, China. ⁴ Department of Vascular Surgery, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, China - rui.feng@shgn.cn.）

出处： International angiology : a journal of the International Union of Angiology 2023

摘要： Background: The aim of this retrospective study was to investigate the outcomes of combining physician-modified endograft (PMEG) and in-situ fenestrat ...

作者： Liang Guo  ¹;Shaoling Li  ²;Xing Wang  ³;Yuming Zhu  ¹;Juanjuan Li  ⁴ （Affiliations ¹ Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China. ² Department of Pathology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China. ³ Department of Thoracic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁴ Department of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, China.）

出处： The journal of gene medicine 2023

关键词： VEGFA;hypoxia-inducible factor-1;lung adenocarcinomas;prognosis;spread through air spaces.

摘要： Background: Spread through air spaces (STAS), a newly identified pattern of invasion in lung adenocarcinomas (LACs), is an unfavorable prognostic fact ...

作者： Ying Wang  ¹, Fangru Xie  ¹, Zirui He  ¹, Lingbin Che  ², Xi Chen  ¹, Yuan Yuan  ¹, Changsheng Liu  ¹ （Affiliations ¹ Key Laboratory for Ultrafine Materials of Ministry of Education, Frontiers Science Center for Materiobiology and Dynamic Chemistry, Engineering Research Center for Biomaterials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai, 200237, P. R. China. ² Department of Orthopedics, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, P. R. China.）

出处： Small (Weinheim an der Bergstrasse, Germany) 2023

关键词： NAD+-dependent SIRT1-activated nanoplatforms;aged bone healing;multi-delivery;senescence-specific biomarker validation;stem cell senescence delay.

摘要： Age-related bone defects are a leading cause of disability and mortality in elderly individuals, and targeted therapy to delay the senescence of bone ...

作者： Chuan Ma  ¹, Chuanjiang Jian  ², Lihao Guo  ³, Wenting Li  ², Cai Zhang  ², Li Wang  ³, Miaomiao Yuan  ³, Peng Zhang  ⁴, Jinqiao Dong  ⁵, Ping He  ², Leilei Shi  ³ （Affiliations ¹ Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration, Jinan, 250012, China. ² Department of Pharmacology, The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518033, China. ³ Precision Research Center for Refractory Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201600, China. ⁴ Department of Pharmacy, The Third Affiliated Hospital (The Affiliated Luohu Hospital) of Shenzhen University, 47 Youyi Road, Shenzhen, 518001, China. ⁵ School of Chemistry and Chemical Engineering, Frontiers Science Center for Transformative Molecules and State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, Shanghai, 200240, China.）

出处： Small (Weinheim an der Bergstrasse, Germany) 2023

关键词： adipose browning induction;adipose tissue targeting;hybrid nanoparticles;obesity treatment;photodynamic therapy.

摘要： Photodynamic therapy (PDT), as a means of locally and rapidly inducing adipocyte death via light illumination, in combination with adipose browning in ...

作者： Yue Gao¹;Zhijun Ouyang¹;Siyan Shen¹;Hongwei Yu²;Bingyang Jia¹;Han Wang²;Mingwu Shen¹CA1;Xiangyang Shi¹CA2 （¹State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai 201620, China;²Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, China）

出处： ACS Nano 2023

关键词： dendrimers;manganese dioxide nanoparticles;glucose oxidase;cGAMP;tumor immunotherapy

摘要： Development of a nanoscale drug delivery system that can simultaneously exert efficient tumor therapeutic efficacy while creating the desired antitumo ...

作者： Xiaojing Huang;Zhaoxia Yan;Chao Gong;Zheliang Zhou;Hua Xu;Chunhui Qin;Zhenwei Wang （Affiliations ¹ Department of Anesthesiology and Pain Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. ² Department of Anesthesiology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, No. 110, Gan He Road, Hongkou District, Shanghai, 200437, China. ³ Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. ⁴ Department of Anesthesiology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, No. 110, Gan He Road, Hongkou District, Shanghai, 200437, China. chunhuiqin1@163.com. ⁵ Department of Respiration Medicine, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, No. 110, Gan He Road, Hongkou District, Shanghai, 200437, China. luckytcm@126.com.）

出处： BMC medical education 2023

关键词： Lumbar puncture;Mixed reality;Stimulator;Training.

摘要： Background: The simulation is one of the basic methods of medical education, which is often used for procedural skills training. However, the existing ...

作者： Yifan Zhou;|Yan Lu;|Ye Liu;|Yanan Hou;|Xinyi Qian;|Kaiweisa Abuduxukuer;|Minhong Xiang;|Qing Peng;|Jianfeng Luo （Affiliations ¹ Department of Ophthalmology, Putuo People's Hospital, Tongji University, Shanghai, China. ² Office of Party and Government Affairs, Healthcare Services Center, Yichuan Street Community, Putuo, Shanghai, China. ³ Department of Clinical Medicine, School of Medicine, Soochow University, Suzhou, China. ⁴ Department of Biostatistics, School of Public Health, Fudan University, Shanghai, China. ⁵ NHC Key Laboratory of Health Technology Assessment, Fudan University, Shanghai, China. ⁶ Key Laboratory of Public Health Safety of Ministry of Education, Fudan University, Shanghai, China. ⁷ Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁸ Department of Endocrine and Metabolic Diseases, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁹ Department of Geriatric Psychiatry, Shanghai Mental Health Center, Shanghai, China. ¹⁰ Department of Ophthalmology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China. ¹¹ Department of Ophthalmology, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai, China.）

出处： Frontiers in public health 2023

关键词： China health and retirement longitudinal study;life expectancy;life satisfaction;self-rated health;sensory impairment.

摘要： Purpose: To investigate the impacts of sensory impairments (SIs) including single vision impairment (SVI), single hearing impairment (SHI) and dual se ...