作者： Beijie Qi ^{# 1}, Weihan Yu ^{# 2}, Hanyi Wang ^{# 2}, Yuqi Li ², Shuang Deng ¹, Chengqing Yi ¹ （Affiliations ¹ Department of Orthopedics, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, China. ² Department of Sports Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, Shanghai, China.）

出处： Frontiers in cell and developmental biology 2026

关键词： fibrosis;macrophage-myofibroblast transition;multi-omics;periostin;shoulder stiffness.

摘要： Background: Shoulder stiffness (SS) is a fibrotic disease with pain and reduced range of motion (ROM). The pathogenesis of SS remains unclear. Recent ...

作者： Lushun Yuan ^{# 1 2}, Jihee Han ^{# 3}, Shuzhen Cheng ⁴, Frits R Rosendaal ³, Dennis O Mook-Kanamori ^{3 5}, J Wouter Jukema ^{6 7}, Hans Vink ⁸, Bernard M van den Berg ², Ton J Rabelink ², Astrid van Hylckama Vlieg ³, Uwe J F Tietge ^{9 10}, Ko Willems van Dijk ^{11 12 13}, Ruifang Li-Gao ³ （Affiliations ¹ Department of Vascular Surgery, Intervention Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, People's Republic of China (L.Y.). ² Einthoven Laboratory for Vascular and Regenerative Medicine, Department of Internal Medicine, Nephrology (L.Y., B.M.v.d.B., T.J.R.), Leiden University Medical Center, the Netherlands. ³ Department of Clinical Epidemiology (J.H., F.R.R., D.O.M.-K., A.v.H.V., R.L.-G.), Leiden University Medical Center, the Netherlands. ⁴ National Engineering Research Center of Seafood, Collaborative Innovation Center of Seafood Deep Processing (S.C.), Dalian Polytechnic University, People's Republic of China. ⁵ Department of Public Health and Primary Care (D.O.M.-K.), Leiden University Medical Center, the Netherlands. ⁶ Department of Cardiology (J.W.J.), Leiden University Medical Center, the Netherlands. ⁷ Netherlands Heart Institute, Utrecht (J.W.J.). ⁸ Glycocalyx Research Institute, Alpine, UT (H.V.). ⁹ Division of Clinical Chemistry, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden (U.J.F.T.). ¹⁰ Clinical Chemistry, Karolinska University Laboratory, Karolinska University Hospital, Stockholm, Sweden (U.J.F.T.). ¹¹ Department of Human Genetics (K.W.v.D.), Leiden University Medical Center, the Netherlands. ¹² Division of Endocrinology, Department of Internal Medicine (K.W.v.D.), Leiden University Medical Center, the Netherlands. ¹³ Leiden Laboratory for Experimental Vascular Medicine (K.W.v.D.), Leiden University Medical Center, the Netherlands.）

出处： Arteriosclerosis, thrombosis, and vascular biology 2026

关键词： antioxidants;cardiovascular diseases;thrombin;triglycerides;venous thromboembolism.

摘要： Background: Recent evidence points to connections between HDLs (high-density lipoproteins), the coagulation system, and venous thromboembolism occurre ...

作者： Yang Fu ¹, Binqiang Xu ², Wenfei Qin ³, Wei Xiao ⁴, Huizhen Huang ², Jia Hu ², Mengyan Cui ², Qixiang Mei ², Junjie Fan ⁵, Chunlan Huang ⁶, Yue Zeng ⁷ （Affiliations ¹ Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, China; Institute of Pancreatic Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, China; Department of Gastroenterology, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, 225001 China. ² Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, China; Institute of Pancreatic Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, China. ³ School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China. ⁴ School of Health Science and Engineering, Shanghai Engineering Research Center of Food Microbiology, University of Shanghai for Science and Technology, Shanghai 200093, China. ⁵ Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, China; Institute of Pancreatic Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, China. Electronic address: 956937215@qq.com. ⁶ Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, China; Institute of Pancreatic Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, China. Electronic address: chunlan.huang@shgh.cn. ⁷ Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, China; Institute of Pancreatic Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, China. Electronic address: carrie_1004@sjtu.edu.cn.）

出处： Cellular and molecular gastroenterology and hepatology 2026

关键词： Blautia coccoides;acute pancreatitis;bile salt hydrolase;deoxycholic acid;farnesoid X receptor.

摘要： Background & aims: Gut dysbiosis is involved in the pathogenesis of acute pancreatitis (AP), yet therapeutic interventions remain limited. Our previou ...

作者： Xiao Feng ^{# 1}, Yi-Wei Wang ^{# 2}, Si-Jia He ^{3 4}, Qian Huang ⁵ （Affiliations ¹ Cancer Center, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, No. 7 Weiwu Road, Jinshui District, Zhengzhou, 450003, Henan, China. ² Department of Radiation Oncology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Rui Jin Er Road, Huangpu District, Shanghai, 200025, China. ³ Cancer Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 650 Xin Songjiang Road, Songjiang District, Shanghai, 201600, China. he-si-jia@163.com. ⁴ Department of Oncology, Jiuquan Branch of Shanghai General Hospital, No. 9 Fengdian Avenue, Suzhou District, Jiuquan, 735000, Gansu, China. he-si-jia@163.com. ⁵ Molecular Diagnostics Laboratory of Cancer Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 650 Xin Songjiang Road, Songjiang District, Shanghai, 201600, China. qian.huang@shgh.cn.）

出处： Cancer cell international 2026

关键词： Apoptosis;Caspase-3;Non-apoptotic roles;Tumor repopulation;Tumor-promoting roles.

作者： Yao Liu ¹, Xue Han ², Weijie Zhang ¹, Qingguo Pei ³, Shuyu Xu ¹, Haicheng Wang ¹ （Affiliations ¹ Department of Implantology, Stomatological Hospital and Dental School of Tongji University, Shanghai Engineering Research Center of Tooth Restoration and Regeneration, Shanghai, China. ² Department of Pediatric Dentistry, Stomatological Hospital and Dental School of Tongji University, Shanghai Engineering Research Center of Tooth Restoration and Regeneration, Shanghai, China. ³ Department of Stomatology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Frontiers in immunology 2026

关键词： glial cell;immunity;neuroinflammation;nociceptive pain;trigeminal ganglion;ultrasonic therapy.

摘要： Background: Neuroinflammation significantly contributes to trigeminal neuropathic pain (TNP). Low-intensity pulsed ultrasound (LIPUS) showed anti-infl ...

作者： Kaiyuan Liu  ^{1   2}, Ruotong Li  ¹, Li Zhang  ³, Hengli Lu  ², Binhui Yang  ², Qian Hu  ¹, Yining Tao  ², Haoran Mu  ², Jing Han  ², Pengfei Zan  ², Jiakang Shen  ², Dongqing Zuo  ², Hongsheng Wang  ², Wei Sun  ², Xingjun Zhu  ^{1   4} （Affiliations ¹ School of Physical Science and Technology & State Key Laboratory of Advanced Medical Materials and Devices, ShanghaiTech University, Shanghai, P. R. China. ² Department of Bone Tumor Surgery, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, P. R. China. ³ Department of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Shanghai Changzheng Hospital, Naval Medical University, Shanghai, P. R. China. ⁴ Shanghai Clinical Research and Trial Center, Shanghai, China.）

出处： Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026

关键词： aggregation‐induced emission (AIE);alkaline phosphatase (ALP);immunotherapy;osteosarcoma;photothermal/photodynamic therapy (PTT/PDT).

摘要： In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's immunosuppressive nature, maki ...

作者： Fei Lyu ¹, Dai Shi ¹, Kapil Sugand ², Xingguang Tao ³, Jianhong Wu ⁴, Zheng Xu ¹, Huixiang Wang ⁵ （Affiliations ¹ Department of Orthopaedics, Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, China. ² Peripheral Nerve Injury Unit, Royal National Orthopaedic Hospital, Stanmore, UK. ³ Department of Orthopedics, Qingpu Branch of Zhongshan Hospital, Fudan University, Shanghai, China. ⁴ Orthopedic Traumatology, Trauma Center, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. ⁵ Department of Orthopedics, National Orthopedic Center, Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： International journal of surgery (London, England) 2026

关键词： arthroscopic surgery;functional outcome;re-tear;rotator cuff tears;salmon calcitonin.

摘要： Background: Rotator cuff tears (RCTs) are the most common shoulder disorder, which can be effectively treated by arthroscopic technique. However, post ...

作者： Enhui Zhou ^{# 1 2 3}, Feifei Xu ^{# 1 2 3}, Tianjiao Zhou ^{# 1 2 3}, Jingyu Zhang ^{1 2 3}, Fan Song ^{1 2 4}, Jianxiang Li ⁵, Hongliang Yi ^{1 2 3}, Qingliang Wang ⁶, Weijun Huang ^{1 2 3} （Affiliations ¹ Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Shanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, China. ³ Otolaryngology Institute of Shanghai Jiao Tong University, Shanghai, China. ⁴ Department of Otorhinolaryngology Head and Neck Surgery, Shanghai General Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁵ Department of Otolaryngology, Shanghai Sixth People's Hospital Fujian, Jinjiang, China. ⁶ Department of Hepatobiliary-Pancreatic-Splenic Surgery, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.）

出处： Frontiers in oncology 2026

关键词： Bayesian age-period-cohort model;global burden of disease;incidence;mortality;nasopharyngeal carcinoma.

摘要： Background: Nasopharyngeal carcinoma (NPC) exhibits pronounced geographical variation, with a high burden in specific regions. We assessed global, reg ...

作者： Zhipeng Zhu ¹, Lanlan Yuan ², Wen Zhu ³, Jigao Yang ⁴, Lan Shi ¹, Qunshan Shen ⁵, Zhou Zhang ⁶, Peiyu Liang ⁷, Zuowen Liang ⁸, Sun Can ⁹, Zhiwen Tao ⁹, Yong Zhu ⁹, Feng Jiang ¹⁰, Yang Gao ¹¹, Guihua Gong ¹², Xiaojun Wang ¹³, Yichao Huang ¹⁴, Yunxia Cao ³, Yushan Li ¹⁵, Xiaojin He ¹⁶, Mei Zhao ¹⁷, Xinzong Zhang ¹⁸ （Affiliations ¹ Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei 230031, China; NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei 230032, China; Reproductive Medicine Center, Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. ² School of Nursing, Anhui Medical University, Hefei 230032, China. ³ Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei 230031, China; NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei 230032, China. ⁴ Human Sperm Bank, Chongqing Research Institute for Population and Family Planning Science and Technology, Chongqing 400020, China. ⁵ Human Sperm Bank, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China. ⁶ Assisted Reproduction Center, Northwest Women's and Children's Hospital, Xi'an 710003, China. ⁷ Department of Urology, the First Affiliated Hospital of Hainan Medical University, Haikou 570216, China. ⁸ Department of Andrology, First Hospital of Jilin University, Changchun 130061, China. ⁹ Obstetrics and Gynecology Hospital, Institute of Reproduction and Development, Fudan University, Shanghai 200011, China. ¹⁰ Shanghai Ji Ai Genetics and IVF Institute, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China. ¹¹ Reproductive Medicine Center, Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. ¹² Human Sperm Bank of Chifeng Gynecology and Obstetrics Hospital, Chifeng, Inner Mongolia 024050, China. ¹³ Maternal and Child Health Hospital of Urumqi, Urumqi 830001, China. ¹⁴ Key Laboratory of Environmental Toxicology of Anhui Higher Education Institutes, Anhui Medical University, Hefei 230032, China; Department of Toxicology, School of Public Health, Anhui Medical University, Hefei 230032, China. ¹⁵ Henan Human Sperm Bank, the Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, China. ¹⁶ Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei 230031, China; NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei 230032, China; Reproductive Medicine Center, Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. Electronic address: hxj0117@126.com. ¹⁷ School of Nursing, Anhui Medical University, Hefei 230032, China. Electronic address: zhaomei@ahmu.edu.cn. ¹⁸ NHC Key Laboratory of Male Reproduction and Genetics, Guangdong Provincial Reproductive Science Institute, Guangzhou 510600, China. Electronic address: 291928148@qq.com.）

出处： Ecotoxicology and environmental safety 2026

关键词： Adult men;Joint effects;Ozone;Residential greenness;Semen quality.

摘要： Epidemiological studies have linked ambient ozone (O₃) and residential greenness to semen quality, but their interaction has rarely been explored. We ...

作者： Xintao Li ¹, Man Li ², Liuliu Cao ³, Shangsong Shi ¹, Ningning Zheng ¹, Shi Peng ¹, Bo Guan ⁴, Tingbo Jiang ¹, Shaowen Liu ⁵, Gary Tse ⁶, Bin Jiang ¹, Shouling Wu ⁷, Lin Ling ⁸, Jia Lin ⁹ （Affiliations ¹ Department of Cardiology, The First Affiliated Hospital of Soochow University, Jiangsu 215000, China. ² Department of Intensive Care Unit, The First Affiliated Hospital of Jinan University, Guangzhou 510632, China. ³ Department of Emergency, The Affiliated Hospital of North China University of Science and Technology, Hebei, China. ⁴ Department of Geriatrics, Suzhou Municipal Hospital, Jiangsu 215000, China. ⁵ Department of Cardiology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. ⁶ School of Nursing and Health Sciences, Hong Kong Metropolitan University, Hong Kong, China. ⁷ Department of Cardiology, Kailuan General Hospital, Tangshan 063000, China. Electronic address: drwusl@163.com. ⁸ Department of Cardiology, The First Affiliated Hospital of Soochow University, Jiangsu 215000, China. Electronic address: joylinling@126.com. ⁹ Department of Cardiology, The First Affiliated Hospital of Soochow University, Jiangsu 215000, China. Electronic address: linjia1234@suda.edu.cn.）

出处： Heart rhythm 2026

关键词： Atrioventricular block;Cardiac conduction block;Cohort study;Left bundle branch block;Remnant cholesterol;Right bundle branch block;Risk factor.

摘要： Background: Elevated remnant cholesterol (RC) is recognized as a risk factor for atherosclerotic cardiovascular disease. However, its association with ...