作者： Xintao Li ¹, Man Li ², Liuliu Cao ³, Shangsong Shi ¹, Ningning Zheng ¹, Shi Peng ¹, Bo Guan ⁴, Tingbo Jiang ¹, Shaowen Liu ⁵, Gary Tse ⁶, Bin Jiang ¹, Shouling Wu ⁷, Lin Ling ⁸, Jia Lin ⁹ （Affiliations ¹ Department of Cardiology, The First Affiliated Hospital of Soochow University, Jiangsu 215000, China. ² Department of Intensive Care Unit, The First Affiliated Hospital of Jinan University, Guangzhou 510632, China. ³ Department of Emergency, The Affiliated Hospital of North China University of Science and Technology, Hebei, China. ⁴ Department of Geriatrics, Suzhou Municipal Hospital, Jiangsu 215000, China. ⁵ Department of Cardiology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. ⁶ School of Nursing and Health Sciences, Hong Kong Metropolitan University, Hong Kong, China. ⁷ Department of Cardiology, Kailuan General Hospital, Tangshan 063000, China. Electronic address: drwusl@163.com. ⁸ Department of Cardiology, The First Affiliated Hospital of Soochow University, Jiangsu 215000, China. Electronic address: joylinling@126.com. ⁹ Department of Cardiology, The First Affiliated Hospital of Soochow University, Jiangsu 215000, China. Electronic address: linjia1234@suda.edu.cn.）

出处： Heart rhythm 2026

关键词： Atrioventricular block;Cardiac conduction block;Cohort study;Left bundle branch block;Remnant cholesterol;Right bundle branch block;Risk factor.

摘要： Background: Elevated remnant cholesterol (RC) is recognized as a risk factor for atherosclerotic cardiovascular disease. However, its association with ...

作者： Yan Xia ¹, Xiaoqing Zhang ², Yuan Liu ³, Jinxin Sheng ⁴, Shijie Hu ¹, Jiarong Li ⁵, Liyun Yuan ⁶, Song Zhu ⁷, Hong Li ⁵, Xiangsong Wu ^{8 9}, Junwei Fan ^{1 7} （Affiliations ¹ Department of General Surgery, Shanghai General Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of Pharmacy, The International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁴ Department of General Surgery, Nantong Haimen People's Hospital, Jiangsu, China. ⁵ Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China. ⁶ Bio-Med Big Data Center, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China. ⁷ Department of General Surgery, Shidong Hospital Affiliated to University of Shanghai for Science and Technology, Shanghai, China. ⁸ Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁹ Department of General Surgery, Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.）

出处： International journal of surgery (London, England) 2026

关键词： PRDX1;gallbladder adenomyomatosis;gallbladder carcinoma;macrophage;single-cell RNA sequencing;tumor microenvironment.

摘要： Background: While the inflammation-to-carcinoma transition in gallbladder carcinogenesis is well recognized, the molecular pathogenesis of gallbladder ...

作者： Xin Zhang ^{# 1}, Jianan Zhe ^{# 1}, Changling Duan ^{# 2}, Xinyi Wei ¹, Zhong He ^{1 3}, Chengran Shi ¹, Lei Yuan ⁴, Hao Wen ⁵, Wei Bao ^{6 7}, Qiong Fan ⁸ （Affiliations ¹ Department of Gynecologic Oncology, Shanghai Key Laboratory of Embryo Original Diseases, The International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, No. 910, Hengshan Road, Shanghai, 200030, China. ² Department of Gynecologic Oncology, Shanghai Geriatric Medical Center, Shanghai, 201100, China. ³ Department of Obstetrics and Gynecology, SongJiang Matertity and Child Health Hospital, No. 1010, Xilin North Road, Shanghai, 201620, China. ⁴ Department of Gynecologic Oncology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, 200001, China. ⁵ Department of Gynecologic Oncology, Fudan University Shanghai Cancer Center, Shanghai, 200032, China. ⁶ Department of Gynecology, Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, 200092, China. forever_chipper@hotmail.com. ⁷ Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 100, Haining Road, Shanghai, 200080, China. forever_chipper@hotmail.com. ⁸ Department of Gynecologic Oncology, Shanghai Key Laboratory of Embryo Original Diseases, The International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, No. 910, Hengshan Road, Shanghai, 200030, China. sailajoan@hotmail.com.）

出处： Cell communication and signaling : CCS 2026

关键词： Apoptotic bodies;Biogenesis and regulation;Blebbisomes;Cargo and function;Drug delivery vehicles;Exophers;Immune evasion;Immunotherapy targets;Large extracellular vesicles;Large oncosomes;Liquid biopsy;Local invasion;Microvesicles;Midbody remnants;Migrasomes;Tumor immunology;Tumor microenvironment.

摘要： Large extracellular vesicles (lEVs), particularly the recently identified blebbisomes, are emerging as critical mediators of tumor progression and int ...

作者： Leheng Liu ^{#  1   2}, Xi Zhang ^{#  3   4}, Chuanyang Wang ^{#  1   2}, Kena Zhou  ^{1   2}, Jingpiao Bao  ^{1   2}, Zhiyuan Cheng  ^{1   2}, Haoran Sun  ^{1   2}, Chengying Zhu  ^{1   2}, Ge Yu  ^{1   2}, Wenqin Xiao  ^{1   2}, Rong Wan  ^{1   2} （Affiliations ¹ Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Shanghai Key Laboratory of Pancreatic Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ School of Basic Medical Science, Center for Big Data and Population Health of Institute of Health and Medicine (IHM), Anhui Medical University, Hefei, China. ⁴ Institute of Health and Medicine, Hefei Comprehensive National Science Center, Hefei, China.）

出处： Frontiers in immunology 2026

关键词： MGB axis;anxiety;chronic pancreatitis;depression;gut microbiota.

摘要： Background: Anxiety and depression are common psychological complications in patients with chronic pancreatitis (CP). This study aims to investigate t ...

作者： Yingjia Xu  ¹, Min Xiao  ², Qin Zhu  ², Wutao Wang  ², Danrui Wang  ², Dadong Liu  ², Zongying Yu  ³ （Affiliations ¹ Department of Cardiology, The Fifth People's Hospital of Wujiang District, Suzhou, Jiangsu, China. ² Department of Critical Care Medicine, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China. ³ Department of Critical Care Medicine, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： PloS one 2026

摘要： Background: CXCR4hi neutrophil mobilization is a key cause of myocardial damage after acute myocardial infarction (AMI). 6-Phosphofructo-2-kinase/fruc ...

作者： Chun Bi¹;Wen Fei²;Haoquan Zhang²;Jian Song²CA1;Shixing Chen²;Yanzhi Dou^3,4;Shiping Song^3,4CA2;Yifu Zhuang¹CA3;Lei Cao¹CA4 （¹Department of Orthopedics Trauma, Trauma Center, Shanghai General Hospital, Shanghai 201620, PR China;²School of Microelectronics, Shanghai University, Shanghai 201800, PR China;³Institute of Materiobiology, College of Science, Shanghai University, Shanghai 200444, China;⁴Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China）

出处： JACS Au 2026

关键词： sweat;carbon nanotubes;electrochemical biosensor;uric acid;glucose;personalized healthcare

摘要： High Resolution Image Download MS PowerPoint Slide Wearable sweat sensors have emerged as promising tools for noninvasive health monitoring, yet the l ...

作者： Chenliang Pan ^{#  1}, Dingding Xu ^{#  2}, Zixin Wang ^{#  1}, Jia Wen  ¹, Lili Ma  ³, Yajuan Zhang  ¹ （Affiliations ¹ Department of Nursing, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of Nursing, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ Department of Nursing, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.）

出处： Frontiers in medicine 2026

关键词： NICU;diaphragm thickening fraction;mNUTRIC score;mechanical ventilation;nursing assessment.

摘要： Background: Critically ill neurosurgical patients on prolonged mechanical ventilation rapidly develop muscle wasting and malnutrition that hinder wean ...

作者： Wenjing Tang ^{#  1   2}, Wenjie Chen ^{#  1}, Na Li ^{#  1}, Wei Li ^{#  3}, Zhigang Lei ^{#  1}, Wenhui Sun  ¹, Xuan Xie  ¹, Yihong Jiang  ¹, Ying Chen  ¹, Lei Xu  ¹, Jifeng Zhu  ¹, Yalin Li  ¹, Jiahao Sha  ⁴, Yang Dai  ⁵, Sha Zhou  ¹, Xiaojun Chen  ⁶, Chuan Su  ¹ （Affiliations ¹ State Key Laboratory of Reproductive Medicine and Offspring Health, National Vaccine Innovation Platform of Nanjing Medical University, Key Laboratory for Pathogen Infection and Control of Jiangsu Province, Department of Pathogen Biology and Immunology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, Jiangsu, China. ² Reproductive Medicine Center, Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ Department of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China. ⁴ State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, Jiangsu, China. ⁵ National Health Commission Key Laboratory of Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Provincial Medical Key Laboratory, Jiangsu Institute of Parasitic Diseases, Wuxi, Jiangsu, China. ⁶ Key Laboratory for Pathogen Infection and Control of Jiangsu Province, Department of Pathogen Biology and Immunology, School of Basic Medical Sciences, the Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Nanjing, Jiangsu, China.）

出处： Frontiers in immunology 2026

关键词： CXCL9 and CXCL10;TRIM21;infection-induced orchitis;lactylation;macrophage.

摘要： Introduction: Infection-induced orchitis, a leading cause of acquired male infertility affecting 8%-12% of couples globally, is driven by unresolved i ...

作者： Yining Tao  ¹, Qi Zhang  ¹, Haoyu Wang  ¹, Binghui Yang  ¹, Haoran Mu  ¹, Kaiyuan Liu  ¹, Weisong Zhao  ¹, Xiyu Yang  ¹, Bowen Zhao  ², Dongqing Zuo  ³, Liu Yang  ¹, Zhengdong Cai  ⁴, Zongyi Wang  ¹, Hongsheng Wang  ⁵, Yingqi Hua  ⁶, Wei Sun  ¹ （Affiliations ¹ Shanghai Jiao Tong University Shanghai China. ² Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University Shanghai China. ³ Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine Shanghai China. ⁴ Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China Shanghai China. ⁵ Shanghai General Hospital Shanghai China. ⁶ Shanghai First People's Hospital Shanghai China.）

出处： Cancer research 2026

摘要： MYC genomic amplification and pathway activation is associated with aggressive behavior and poor prognosis in osteosarcoma (OS). However, a discordanc ...

作者： Jiuliang Yan  ^{1   2}, Hanguang Dong  ^{1   2}, Chuntao Wu  ^{1   2}, Haitao Gu  ^{1   2}, Zihao Qi  ^{1   2}, Tao Chen  ^{1   2}, Beiyuan Hu  ^{1   2}, Huijiang Zhou  ^{1   2}, Jiang Long  ^{1   2} （Affiliations ¹ Department of Pancreatic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Shanghai Key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Frontiers in oncology 2026

关键词： AK112;PD-1;VEGF-A;bispecific antibody;chemotherapy;locally advanced pancreatic cancer.

摘要： Background: Pancreatic ductal adenocarcinoma (PDAC) is one of the most malignant tumors. Most patients are diagnosed at advanced or metastatic stages, ...