作者： Yu Lv^1,2,3;Xia Wang^1,3;Youjie Zeng⁴;Zizhao Tang^1,5;Fangqin Nie^1,6;Ren Guo¹CA1 （¹Department of Pharmacy, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, China;²Department of Orthopaedics, Shanghai Bone Tumor Institute, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China;³These authors contributed equally to this work.;⁴Department of Anesthesiology, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, China;⁵Department of Pharmacy, The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;⁶Department of Pharmacy, Hospital/School Of Stomatology, Zunyi Medical University, Zunyi, Guizhou 563000, China）

出处： Tissue and Cell 2025

摘要： Introduction The phenotypic transition of vascular smooth muscle cells (VSMCs) from a quiescent, contractile type to a secretory phenotype with high p ...

作者： Bingxin Li  ¹, Xiaoyun Feng  ¹, Yihan Zhang  ¹, Yunhong Huang  ¹, Mingyu Gu  ¹, Haiyan Sun  ¹, Wenqian Ren  ¹, Qin Zhen  ¹, Tingting Shen  ¹, Ling Pan  ¹, Tingting Fan  ¹, Qin Qin  ¹, Fang Liu  ¹, Yongde Peng  ¹, Yufan Wang  ¹, Huanbai Xu  ¹ （Affiliation ¹ Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghais, China.）

出处： Virulence 2025

关键词： COVID-19;COVID-19 vaccines;Hashimoto Thyroiditis;clinical chemistry tests;hypothyroidism;thyroid function tests.

摘要： The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread rapidly, leading to an Omicron outbreak in Shanghai in mid-December after adju ...

作者： Jingjing Li  ¹, Zhicheng Dai  ², Zhengwei Zhang  ³, Chen Chen  ⁴, Xuehui Xiong  ⁵, Falin Xu  ¹ （Affiliations ¹ Department of Neonatal, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China. ² Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ Department of Pathology, Changzheng Hospital, Naval Medical University, Shanghai, China. ⁴ Department of Psychiatry, School of Mental Health and Psychological Sciences, Anhui Medical University, Hefei, China. ⁵ Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Expert opinion on drug safety 2025

关键词： FAERS;adverse events;disproportionate analysis;gabapentinoids;psychiatric disorders.

摘要： Background: Gabapentinoids, including gabapentin and pregabalin, are commonly used for neuropathic pain but have safety concerns. This study analyzed ...

作者： Huihui Wu¹;Liang Zhu²;Xia Geng³;Xiaona Guo³;Tingting Wang³;Jingjing Xu³;Linkai Jiang³;Weibo Zhang⁴CA （¹a Department of Anesthesiology, Shanghai General Hospital, Shanghai, China;²b Rehabilitation Medicine Center, West China Hospital, Sichuan University, Chengdu, China;³c Department of Pain, Dongying People’s Hospital, Dongying, Shandong, China;⁴d Department of Anesthesiology, Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, Hangzhou, China）

出处： Neurological Research 2025

关键词： Chronic constriction injury;inflammation;Schwann cell;miRNA;target

摘要： Objectives Due to the complex and unclear pathogenesis of neuropathic pain, there is a lack of effective therapeutic strategy. miR-363-5p was consider ...

作者： Siguo Feng  ^{1   2}, Qiuyang Zhang  ^{1   2}, Qing Liu  ^{1   2}, Chang Huang  ³, Huiying Zhang  ^{1   2}, Fengsheng Wang  ^{1   2}, Yue Zhu  ^{1   2}, Qizhi Jian  ⁴, Xue Chen  ⁵, Qin Jiang  ^{1   2}, Biao Yan  ⁴ （Affiliations ¹ The Affiliated Eye Hospital, Nanjing Medical University, Nanjing, China. ² The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, China. ³ Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China. ⁴ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁵ Department of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing, China.）

出处： Diabetes 2025

摘要： Diabetic vasculopathy, encompassing complications such as diabetic retinopathy, represents a significant source of morbidity, with inflammation playin ...

作者： Runzhi Huang ^{#  1   2   3}, Jiaying Shi ^{#  4}, Yifan Liu ^{#  5}, Shuyuan Xian ^{#  2   3}, Wei Zhang ^{#  2   3}, Yuntao Yao  ⁵, Xinru Wu  ⁴, Yuanan Li  ⁴, Haoyu Zhang  ⁴, Bingnan Lu  ⁵, Jiajie Zhou  ⁴, Yibin Zhou  ⁴, Min Lin  ⁶, Xiaonan Wang  ⁷, Xin Liu  ⁸, Yue Wang  ⁹, Wenfang Chen  ¹⁰, Chongyou Zhang  ¹¹, Erbin Du  ¹², Qing Lin  ¹³, Zongqiang Huang  ¹⁴, Yu Chen  ¹⁵, Jie Zhang  ¹⁶, Jun Liu  ¹⁷, Xihui Chen  ¹⁸, Xiuwu Pan  ¹⁹, Xingang Cui  ²⁰, Shizhao Ji  ^{21   22}, Huabin Yin  ²³ （Affiliations ¹ Department of Orthopedics, School of Medicine, Shanghai General Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 100 Haining Road, Shanghai, China. ² Department of Burn Surgery, the First Affiliated Hospital of Naval Medical University, Shanghai, People's Republic of China. ³ Research Unit of key techniques for treatment of burns and combined burns and trauma injury, Chinese Academy of Medical Sciences, Shanghai, People's Republic of China. ⁴ Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. ⁵ Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China. ⁶ Mental Health Education and Consultation Center, Chongqing Medical University, 61 Daxuecheng Middle Road, Chongqing, 401331, China. linmin_513@163.com. ⁷ Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing, 100069, China. hnaywxn@163.com. ⁸ Department of Rheumatology and Immunology, Second Affiliated Hospital of Naval Medical University, Shanghai, China. lxsmmu@163.com. ⁹ Department of Health Statistics, School of Public Health, Air Force Medical University, Xi'an, 710032, China. wangyuek11@126.com. ¹⁰ Faculty of Medicine, Jinggangshan University, Ji'An, 343009, China. 9919970039@jgs.edu.cn. ¹¹ Basic Medical College, Harbin Medical University, Heilongjiang, 150081, China. cyzhanghmu@sina.com. ¹² Frist Clinical Medical College, Mudanjiang Medical University, Mudanjiang, 157011, China. 1748855216@qq.com. ¹³ Department of Human Anatomy, Laboratory of Clinical Applied Anatomy, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, 350122, China. linqing522@126.com. ¹⁴ Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. gzhuangzq@163.com. ¹⁵ Department of Gynecology and Obstetrics, The First Affiliated Hospital of Naval Medical University, Yangpu District, No. 168 Changhai Road, Shanghai, 200433, China. yueryw@163.com. ¹⁶ Department of Gynecology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, 201204, China. jiezhang@tongji.edu.cn. ¹⁷ Department of Anesthesiology, Shanghai Pulmonary Hospital Affiliated to Tongji University, 507 Zheng Min Road, Shanghai, 200433, China. yirong007@126.com. ¹⁸ Clinical Education Centre, the, First Affiliated Hospital , PLA Naval Medical University, Shanghai, 200433, China. cxh840808@126.com. ¹⁹ Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China. panxiuwu@126.com. ²⁰ Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China. cuixingang@xinhuamed.com.cn. ²¹ Department of Burn Surgery, the First Affiliated Hospital of Naval Medical University, Shanghai, People's Republic of China. shizhaoji2022@163.com. ²² Research Unit of key techniques for treatment of burns and combined burns and trauma injury, Chinese Academy of Medical Sciences, Shanghai, People's Republic of China. shizhaoji2022@163.com. ²³ Department of Orthopedics, School of Medicine, Shanghai General Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 100 Haining Road, Shanghai, China. yinhuabin@aliyun.com.）

出处： BMC psychology 2025

关键词： Empathy;Jefferson Scale of Empathy (JSE);Learning environment (LE);Medical students.

摘要： Background: Empathy of medical students is crucial, yet it tends to decline as students enter later academic years. Empathy appeared to be affected by ...

作者： Jinghan Song  ¹, Xiong Ye  ², Hui Xiao  ¹ （Affiliations ¹ Department of Respiratory and Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: xiaohui771210@163.com. ² School of Clinical Medicine, Shanghai University of Medicine & Health Sciences, Shanghai, China.）

出处： Critical reviews in oncology/hematology 2025

关键词： Antineoplastic treatment;Cancer screening;Clinical application;Liquid biopsy;Metastasis;Recurrence.

摘要： In recent years, liquid biopsy has gained prominence as an emerging biomarker in cancer research, providing critical insights into tumor biology and m ...

作者： Min Zhang  ^{1   2}, Jiali Wu  ^{1   2}, Yimin Wang  ³, Yidong Wu  ^{1   2}, Xiaoling Wan  ^{1   2}, Mei Jiang  ^{1   2}, Qiyu Bo  ^{1   2}, Jieqiong Chen  ^{1   2}, Xiaodong Sun  ^{1   2   4   5} （Affiliations ¹ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China. ² National Clinical Research Center for Ophthalmic Diseases, Shanghai, China. ³ Department of Ophthalmology, Zhongshan Hospital, Fudan University, Shanghai, China. ⁴ Shanghai Key Laboratory of Fundus Diseases, Shanghai, China. ⁵ Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China.）

出处： Aging cell 2025

关键词： EndMT;VASH1;circSIRT2;miR‐542‐3p;subretinal fibrosis.

摘要： Neovascular age-related macular degeneration (nAMD), characterized by choroidal neovascularization (CNV), is one of the leading causes of severe visua ...

作者： Qinqin Cai^1,2;Qiao Zhao^1,2;Qingxia Yang¹;Min Zhu¹;Fufen Meng¹CA1;Jihong Jiang³CA2 （¹Department of Anesthesiology, Xinjiang Medical University Affiliated Cancer Hospital, Urumqi, Xinjiang, China;²These authors contributed equally to this work.;³Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China）

出处： Experimental Cell Research 2025

关键词： Ku70;Ku86;P300;Diabetic kidney injury;Glomerular endothelial cell

摘要： Endothelial inflammation caused by hyperglycemia contributes to cardiovascular complications in patients with diabetes. Diabetic kidney injury (DKI) i ...

作者： Huibiao Deng  ¹, Peng Wang  ², Minxing Liu  ³ （Affiliations ¹ Department of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China. ² Department of Emergency, The First Affiliated Hospital of Soochow University, No.899, Pinghai Road, Gusu District, Suzhou City, Jiangsu Province, 215031, China. ³ Department of Emergency, The First Affiliated Hospital of Soochow University, No.899, Pinghai Road, Gusu District, Suzhou City, Jiangsu Province, 215031, China. minxingliu0921@163.com.）

出处： Journal of cardiothoracic surgery 2025

关键词： Intensive care unit;Prognostic value;Pulmonary hypertension.

摘要： Background: The impact of pulmonary hypertension (PH) on critically ill patients has not been fully understood. Our objective was to explore the possi ...