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作者: Xiue Ma 1, Liming Gao 2, Rucun Ge 3, Tianyou Yuan 4, Bowen Lin 5, Lixiao Zhen 6 (Affiliations 1 School of Medicine, Tongji University, Shanghai, 200092, China. 2 Department of Cardiology, Ji'an Hospital, Shanghai East Hospital, Ji'an, 343000, Jiangxi, China. 3 Shandong Provincial Third Hospital, Shandong University, Jinan, 250012, Shandong, China. 4 Department of Cardiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China. tianyou_yuan@163.com. 5 School of Medicine, Tongji University, Shanghai, 200092, China. bowenlin0512@163.com. 6 Shandong Provincial Third Hospital, Shandong University, Jinan, 250012, Shandong, China. zlxiao56@163.com.)
出处: In vitro cellular & developmental biology. Animal 2024
关键词: AKT;CDC-like kinase 3;Cardiomyocyte apoptosis;Hypoxia.
摘要: Hypoxia-induced cardiomyocyte apoptosis is one major pathological change of acute myocardial infarction (AMI), but the underlying mechanism remains un ...
作者: Qingqing Zhang 1 2, Bingye Zhu 3, Hongyan Yang 4, Fei Li 1 2, Ying Qu 1 2, Lungen Lu 1 2, Qidi Zhang 1 2 (Affiliations 1 Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 Shanghai Key Laboratory of Pancreatic Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 3 Department of Urology, Affiliated Nantong Hospital of Shanghai University, The Sixth People's Hospital of Nantong, Nantong, Jiangsu Province, China. 4 Nursing Department, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.)
出处: The journal of gene medicine 2024
关键词: YBX1;liver hepatocellular carcinoma;prognosis;single-cell and bulk sequencing analysis;tumor immunity.
摘要: Background: Y-box binding protein 1 (YBX1) plays a variety of roles in progression of multiple tumors. However, the role of YBX1 in prognostic value a ...
作者: Siteng Chen 1, Feng Gao 2, Tuanjie Guo 3, Liren Jiang 2, Ning Zhang 4, Xiang Wang 3, Junhua Zheng 1 (Affiliations 1 Department of Urology, Renji Hospital. 2 Department of Pathology. 3 Department of Urology, Shanghai General Hospital. 4 Department of Urology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.)
出处: International journal of surgery (London, England) 2024
摘要: Background: Although separate analysis of individual factor can somewhat improve the prognostic performance, integration of multimodal information int ...
作者: Mengchen Wu 1, Yingxiang Hao 1, Xinwan Wu 1, Minmin Zhu 1 2, Xiangyuan Chen 1, Jie Qi 1, Zhuang Yu 1, Hongjiao Xu 1 (Affiliations 1 Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, China. 2 Department of Anesthesiology, Department of Oncology, Fudan University Shanghai Cancer Center, Shanghai Medical College, Fudan University, Shanghai 200032, China.)
出处: Acta biochimica et biophysica Sinica 2024
关键词: diabetic nephropathy;endothelial-to-mesenchymal transition;glomerular endothelial cell, SirT7.
摘要: Diabetic nephropathy (DN) is the main cause of end-stage renal disease worldwide. It is reported that the endothelial-to-mesenchymal transition (EndMT ...
作者: Lingxuan Zhu 1, Weiming Mou 2, Jiarui Xie 3, Peng Luo 3, Rui Chen 4 (Affiliations 1 Department of Urology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, 160 Pujian Road, Shanghai, 200127, China; Department of Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China. 2 Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 3 Department of Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China. 4 Department of Urology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, 160 Pujian Road, Shanghai, 200127, China. Electronic address: drchenrui@foxmail.com.)
出处: Resuscitation 2024
作者: Bing Zhuang 1, Liangying Gan 2, Bin Liu 3, Weijie Yuan 4, Ming Shi 5, Ai Peng 6, Lihua Wang 7, Xiaolan Chen 8, Tongqiang Liu 9, Shiying Zhang 10, Song Wang 11, Qing Gao 12, Baoxing Wang 13, Huixiao Zheng 14, Changhua Liu 15, Yuan Luo 1, Hong Ye 1, Hongli Lin 16, Yiwen Li 17, Qiang He 17, Feng Zheng 18, Ping Luo 19, Gang Long 20, Wei Lu 21, Kanghui Li 22, Junwei Yang 1, Yingxue Cathy Liu 23, Zhizheng Zhang 23, Xiaolin Li 23, Weifeng Zhang 23, Li Zuo 2 (Affiliations 1 Center for Kidney Disease, Second Affiliated Hospital, Nanjing Medical University, Nanjing, China. 2 Department of Nephrology, Peking University People's Hospital, Beijing, China. 3 Nephrology Department, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China. 4 Nephrology Department, Shanghai General Hospital, Shanghai, China. 5 Nephrology Department, Renmin Hospital of Wuhan University, Wuhan, China. 6 Nephrology Department, Shanghai Tenth Hospital, Shanghai, China. 7 Nephrology Department, The Second Hospital of Shanxi Medical University, Taiyuan, China. 8 Nephrology Department, Affiliated Hospital of Nantong University, Nantong, China. 9 Nephrology Department, Changzhou No. 2 People's Hospital, Changzhou, China. 10 Nephrology Department Jilin Province People's Hospital, Changchun, China. 11 Nephrology Department, Peking University Third Hospital, Beijing, China. 12 Department of Nephrology, Zhongshan Hospital of Xiamen University School of Medicine, Xiamen, China. 13 Nephrology Department, The Third Hospital of Hebei Medical University, Shijiazhuang, China. 14 Nephrology Department, The Second Affiliated Hospital of Xingtai Medical College, Xingtai, China. 15 Nephrology Department, Northern Jiangsu People's Hospital, Yangzhou, China. 16 Nephrology Department, The First Hospital of Dalian Medical University, Dalian, China. 17 Department of Nephrology, Zhejiang Provincial People's Hospital, Hangzhou, China. 18 Nephrology Department, The Second Hospital of Dalian Medical University, Dalian, China. 19 Nephrology Department, The Second Hospital of Jilin University, Changchun, China. 20 Department of Nephrology, Tianjin Union Medical Center, Tianjin, China. 21 Department of Nephrology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. 22 Nephrology Department, The Affiliated Hospital of Guilin Medical University, Guilin, China. 23 Shanghai Alebund Pharmaceuticals Limited, Shanghai, China.)
出处: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2024
关键词: VS-505;clinical study;hemodialysis;hyperphosphatemia;phosphate binder.
摘要: Background: VS-505 (AP301), an acacia and ferric oxyhydroxide polymer, is a novel fiber-iron-based phosphate binder. This two-part phase 2 study evalu ...
作者:
Xiaobin Zhu1;Liu Liu2,3;Shixiong Tian4;Guijun Zhao5;Erlei Zhi6;Qian Chen1;Feng Zhang7;Aijun Zhang1
出处: Molecular Genetics and Genomics 2024
关键词: Male infertility;Asthenoteratospermia;Whole-exome sequencing;FAM71D;ICSI
摘要: Asthenoteratospermia is a significant cause of male infertility. FAM71D (Family with sequence similarity 71, member D), as a novel protein exclusively ...
作者: Mingxing Xia 1, Zhenyang Shen 2, Haiming Zheng 3, Lin Yuan 4, Jiangfeng Hu 2, Yi Zhao 1, Dongxun Zhou 1, Xianghui Bai 1, Junjun Wang 2, Xiaoman Li 2, Weiming Dai 2, Mei Kang 5, Hui Zhou 2, Rong Wan 2, Lungen Lu 2, Bing Hu 1, Xinjian Wan 3, Xiaobo Cai 2 (Affiliations 1 Department of Gastroenterology and Endoscopy, The Third Affiliated Hospital of Naval Medical University, Shanghai. 2 Department of Gastroenterology, Shanghai general Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 3 Department of Gastroenterology, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai. 4 Department of Pathology, Shanghai general Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai. 5 Clinical Research Center, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai.)
出处: The American journal of gastroenterology 2024
摘要: Objectives: Although cytologic examination of biliary stricture brushings obtained via endoscopic retrograde cholangiopancreatography (ERCP) is common ...
作者: Wen Yang # 1 2 3, Longmei Wu # 1 2 4, Guanjian Li # 1 2 3, Lan Shi # 1 2 3, Junqiang Zhang # 1 2 3, Liting Liu 1 2 3, Yuge Chen 1 2 3, Hui Yu 1 2 3, Kai Wang 1 2 3, Lei Xin 1 2 3, Dongdong Tang 1 2 3, Qunshan Shen 1 2 3, Chuan Xu 1 2 3, Hao Geng 1 2 3, Huan Wu 1 2 3, Zongliu Duan 1 2 3, Yunxia Cao 1 2 3, Xiaojin He 5 6 (Affiliations 1 Reproductive Medicine Center, Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Anhui, 230022, China. 2 NHC Key Laboratory of Study On Abnormal Gametes and Reproductive Tract (Anhui Medical University), Anhui, 230032, China. 3 Key Laboratory of Population Health Across Life Cycle (Anhui Medical University), Ministry of Education of the People's Republic of China, Anhui, 230032, China. 4 Department of Obstetrics and Gynecology, Anhui Public Health Clinical Center, Hefei, China. 5 Reproductive Medicine Center, Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. xiaojinhe@sjtu.edu.cn. 6 NHC Key Laboratory of Study On Abnormal Gametes and Reproductive Tract (Anhui Medical University), Anhui, 230032, China. xiaojinhe@sjtu.edu.cn.)
出处: Environmental science and pollution research international 2024
关键词: Epididymis;Microplastics (MPs);Prostate;Semen;Seminal vesicle;Source of exposure;Testis;pyrolysis-gas chromatography/mass spectrometry (Py-GC/MS).
摘要: Regarding the impact of microplastics (MPs) on the male reproductive system, previous studies have identified a variety of MPs in both human semen and ...
作者: Hang Zhao 1, Wenhua Li 2, Xin Zhou 3, Liang Pan 3, Yun Feng 4, Pingyu Gao 5, Jie Ji 6, Huanyan Zhang 6, Kai Zhao 3, Chi Wang 7, Zhanjun Lu 3 4 (Affiliations 1 Department of Gastroenterology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai, China. 2 Department of Gastroenterology, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 3 Department of Gastroenterology, Jintan Hospital, Jiangsu University, Changzhou, China. 4 Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 5 Pathology Center, Jintan Hospital, Jiangsu University, Zhenjiang, China. 6 Clinical Laboratory, Jintan Hospital, Jiangsu University, Zhenjiang, China. 7 Department of Precision Mechanical Engineering, Shanghai University, Shanghai, China.)
出处: Journal of innate immunity 2024
关键词: CXCL1;Colitis;Gut microbiota;Inflammation;Neutrophil.
摘要: Introduction: C-X-C motif chemokine ligand 1 (CXCL1) is a potent neutrophil chemoattractant that plays a pivotal role in recruiting neutrophils during ...
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