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[外文期刊] Multiparametric MRI and Machine Learning Based Radiomic Models for Preoperative Prediction of Multiple Biological Characteristics in Prostate Cancer SCIE SCI

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作者： Xuhui Fan¹, Ni Xie², Jingwen Chen¹, Tiewen Li³, Rong Cao¹, Hongwei Yu¹, Meijuan He¹, Zilin Wang¹, Yihui Wang¹, Hao Liu⁴, Han Wang^{1 2 5}, Xiaorui Yin¹ （Affiliations 1 Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 Institution for Clinical Research, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 3 Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 4 Department of Research and Development, Yizhun Medical AI Technology Co. Ltd., Beijing, China. 5 Department of Radiology, Jiading Branch of Shanghai General Hospital, Shanghai, China.）

出处： Frontiers in oncology 2022 Vol.12 P839621

关键词： biological characteristics;magnetic resonance imaging;prostate cancer;radiomics;risk stratification.

摘要： Objectives: This study aims to develop and evaluate multiparametric MRI (MP-MRI)-based radiomic models as a noninvasive diagnostic method to predict s ...

[外文期刊] HOXA13 promotes gastric cancer progression partially via the FN1-mediated FAK/Src axis

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作者： Zhiwei Qin¹;Chongzhi Zhou¹CA1 （1 Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 85 Wujin Road, Shanghai, China）

出处： Experimental Hematology & Oncology 2022 Vol.11 No.1

关键词： Gastric cancer;HOXA13;FN1;FAK/Src;miR-449a

摘要： Background Gastric cancer (GC) is one of the most common cancers causing a poor prognosis worldwide. HOXA13, as a member of the homeobox (HOX) family ...

[外文期刊] LncRNA Snhg5 Attenuates Status Epilepticus Induced Inflammation through Regulating NF-κΒ Signaling Pathway SCIE SCI

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作者： Ming Wang¹, Yangmei Xie¹, Yiye Shao², Yinghui Chen¹ （Affiliations 1 Department of Neurology, Huashan Hospital, Fudan University. 2 Department of Neurology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine.）

出处： Biological & pharmaceutical bulletin 2022 Vol.45 No.1 P86-93

关键词： inflammation;microglia;nuclear factor-kappaB (NF-κΒ) signaling pathway;small nucleolar RNA host gene 5;status epilepticus.

摘要： Status epilepticus (SE) induced inflammation plays an important role in the pathogenesis of SE. Long non-coding RNA small nucleolar RNA host gene 5 (l ...

[外文期刊] Comparison of lymphatic contrast-enhanced ultrasound and intravenous contrast-enhanced ultrasound in the preoperative diagnosis of axillary sentinel lymph node metastasis in patients with breast cancer

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作者： Lingling Zhuang¹, Xu Ming², Jun Liu², Chao Jia¹, Yubiao Jin³, Jing Wang³, Qiusheng Shi¹, Rong Wu¹, Lifang Jin¹, Lianfang Du¹ （Affiliations 1 Department of Medical Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China. 2 Department of Breast-Thyroid-Vascular Surgery, Shanghai General Hospital, Shanghai JiaoTong University, School of Medicine, Shanghai, China. 3 Department of Pathology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.）

出处： The British journal of radiology 2022 Vol.95 No.1130 P20210897

摘要： Objectives: This study aimed to compare diagnostic efficiency for axillary sentinel lymph node (SLN) metastasis between lymphatic contrast-enhanced ul ...

[外文期刊] A novel ferroptosis-related gene signature associated with cell cycle for prognosis prediction in patients with clear cell renal cell carcinoma SCIE SCI

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作者： Siteng Chen^#¹, Encheng Zhang^#¹, Tuanjie Guo^#¹, Jialiang Shao¹, Tao Wang¹, Ning Zhang², Xiang Wang³, Junhua Zheng⁴ （Affiliations 1 Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 Department of Urology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. zn12235@rjh.com.cn. 3 Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. seanw_hs@163.com. 4 Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. zhengjh0471@sina.com.）

出处： BMC cancer 2022 Vol.22 No.1 P1

关键词： Cell cycle;Clear cell renal cell carcinoma;Ferroptosis;Nomogram;Prognosis.

摘要： Background: It is of great urgency to explore useful prognostic markers for patients with clear cell renal cell carcinoma (ccRCC). Prognostic models b ...

[外文期刊] Efficacy of Yushen Tongluo Granule Combined with Clomiphene Citrate for Anovulatory Infertility: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial.

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作者： Xu, Huayun¹;Wang, Songpo¹;Gao, Xiaohong²;Wang, Guozeng³ （1 Department of Traditional Chinese Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China 2 Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China 3 Department of Obstetrics and Gynecology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China）

出处： Evidence-based Complementary & Alternative Medicine (eCAM) 2022 P1-7

摘要： Objective. To evaluate the efficacy and safety of Yushen Tongluo Granule (YSTLG) combined with clomiphene citrate (CC) in the treatment of anovulatory ...

[外文期刊] The transcription factor KLF14 regulates macrophage glycolysis and immune function by inhibiting HK2 in sepsis

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作者： Yuan Yuan^#¹, Guangjian Fan^#², Yuqi Liu^#¹, Lu Liu³, Tong Zhang¹, Pengfei Liu¹, Qing Tu¹, Xinyi Zhang¹, Shiyuan Luo⁴, Liangfang Yao⁵, Feng Chen⁶, Jingbao Li⁷ （Affiliations 1 Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 201620, China. 2 Precision Research Center for Refractory Diseases, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 201620, China. 3 Department of Anesthesiology, Weifang Medical University, Weifang, 261000, China. 4 Department of Anesthesiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China. 5 Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 201620, China. yao_elina@163.com. 6 Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 201620, China. smmuchenfeng@163.com. 7 Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 201620, China. lijingbaoshanghai@163.com.）

出处： Cellular & molecular immunology 2022

关键词： Glycolysis;HK2;KLF14;Macrophages;Perhexiline;Sepsis.

摘要： Sepsis is a heterogeneous syndrome induced by a dysregulated host response to infection. Glycolysis plays a role in maintaining the immune function of ...

[外文期刊] Lysophosphatidylcholine acyltransferase 1 promotes epithelial-mesenchymal transition of hepatocellular carcinoma via the Wnt/β-catenin signaling pathway

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作者： Ling Shen¹, Peng Gu², Chen Qiu³, Wen-Tao Ding², Lei Zhang⁴, Wan-Yue Cao², Zu-Yin Li⁵, Bin Yan⁶, Xing Sun⁷ （Affiliations 1 Clinical Medical School, Shanghai General Hospital of Nanjing Medical University, Shanghai, China; Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 3 Institute of Gallstone Disease, Center of Gallbladder Disease, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China. 4 Intervention Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 5 Department of Hepatobiliary Surgery, Peking University Organ Transplantation Institute, Peking University People\'s Hospital, Beijing, China. 6 Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: yanbin8988@sjtu.edu.cn. 7 Clinical Medical School, Shanghai General Hospital of Nanjing Medical University, Shanghai, China; Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: xingsun_sjtu@aliyun.com.）

出处： Annals of hepatology 2022 P100680

关键词： EMT;Hepatocellular carcinoma;LPCAT1;Migration and invasion;Wnt/β-catenin pathway.

摘要： Introduction and objectives: Hepatocellular carcinoma (HCC) is one of the most malignant digestive tumors, and its insidious onset and rapid progressi ...

[外文期刊] Specific knockdown of Y-box binding protein 1 in hepatic progenitor cells inhibits proliferation and alleviates liver fibrosis

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作者： Binghang Li¹, Fei Li¹, Tianyi Gu¹, Yuecheng Guo¹, Bo Shen¹, Xianjun Xu¹, Zhenyang Shen¹, Liuying Chen², Qidi Zhang¹, Hui Dong¹, Xiaobo Cai³, Lungen Lu⁴ （Affiliations 1 Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 201620, China; Shanghai Key Laboratory of Pancreatic Diseases, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 201620, China. 2 Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. 3 Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 201620, China; Shanghai Key Laboratory of Pancreatic Diseases, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 201620, China. Electronic address: caixiaobo19790719@126.com. 4 Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 201620, China; Shanghai Key Laboratory of Pancreatic Diseases, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 201620, China. Electronic address: lungenlu1965@163.com.）

出处： European journal of pharmacology 2022 P174866

关键词： Hepatic progenitor cell;Liver fibrosis;Y-box binding protein 1;p53.

摘要： The proliferation of hepatic progenitor cells (HPCs) contributes to liver regeneration and fibrogenesis during chronic liver injury; however, the mech ...

[外文期刊] Exosomes derived from hepatitis B virus-infected hepatocytes promote liver fibrosis via miR-222/TFRC axis SCIE SCI

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作者： Qidi Zhang^#¹, Ying Qu^#¹, Qingqing Zhang², Fei Li¹, Binghang Li¹, Zhenghong Li¹, Yuwei Dong¹, Lungen Lu³, Xiaobo Cai⁴ （Affiliations 1 Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, No. 650 New Songjiang Road, Shanghai, 201620, China. 2 Department of Gastroenterology, Ruian People\'s Hospital, No. 108 Wansong Road, Ruian, 325200, China. 3 Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, No. 650 New Songjiang Road, Shanghai, 201620, China. lungenlu1965@163.com. 4 Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, No. 650 New Songjiang Road, Shanghai, 201620, China. caixiaobo1979@hotmail.com.）

出处： Cell biology and toxicology 2022

关键词： Exosome;Fe2+;Ferroptosis;Hepatic stellate cell;Hepatitis B virus;Hepatocytes;Lipid ROS;Liver fibrosis;Transferrin receptor;miR-222.

摘要： Exosomal miRNAs activates hepatic stellate cell (HSC) and promote fibrosis. miR-222 was found to be increased in hepatitis B virus (HBV)-infected hepa ...