作者： Hangwei Chen  ¹, Fan Li  ², Yulong Ge  ¹, Junyi Liu  ¹, Xing Xing  ¹, Min Li  ², Zhilei Ge  ³, Xiaolei Zuo  ^{2   3}, Chunhai Fan  ^{2   3}, Shaopeng Wang  ², Fang Wang  ¹ （Affiliations ¹ Department of Cardiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200800, China. ² Institute of Molecular Medicine, Shanghai Key Laboratory for Nucleic Acids Chemistry and Nanomedicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, China. ³ School of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules, Zhangjiang Institute for Advanced Study and National Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai, 200240, China.）

出处： Advanced materials (Deerfield Beach, Fla.) 2024

关键词： Atrial fibrillation;Dox delivery;radiofrequency catheter ablation;tetrahedral DNA framework.

摘要： Pre-organizing molecular drug within a microenvironment is crucial for the development of efficient and controllable therapeutic systems. Here, we rep ...

作者： Ling Xu  ¹, Yue Xuan Wang  ², Wei Wang  ³, Xue Fan  ⁴, Xue Yu Chen  ⁵, Tian Yun Zhou  ⁶, Yu He Liu  ⁷, Ye Yu  ⁸, Fan Yang  ⁹, Zhen Yu Ju  ⁹, Yong Zhou  ¹⁰, Deng Liang Wang  ¹¹ （Affiliations ¹ Clinical Research Institute, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China;NHC Key Lab of Reproduction Regulation, Shanghai Engineering Research Center of Reproductive Health Drugs and Devices, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Shanghai 200237, China. ² Department of Applied Statistics, Johannes Kepler University Linz, Linz 4040, Austria. ³ Hematology Center, Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Discipline of Pediatrics (Capital Medical University), Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China. ⁴ Clinical Research Institute, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. ⁵ Department of Biostatistics, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan 250012, Shandong, China. ⁶ Clinical Medicine, School of Basic Medicine, Shanghai Medical College Fudan University, Shanghai 200032, China. ⁷ Department of Biochemistry and Molecular Biology, Hengyang Medical School, University of South China, Hengyang 421001, Hunan, China. ⁸ Administrative Office, Total Quality Management Office, Total Quality Management Institute, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. ⁹ The First Affiliated Hospital of Jinan University, Institute of Aging and Regenerative Medicine, Jinan University, Jinan 510632, Guangzhou, China. ¹⁰ Clinical Research Institute, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China;Department of Scientific Research, The First Affiliated Hospital of Huzhou University, Huzhou 313000, Zhejiang, China. ¹¹ Department of Neurosurgery, Neurosurgery Research Institute, The First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, Fujian, China;Department of Neurosurgery, Binhai Branch of National Regional Medical Center, The First Affiliated Hospital, Fujian Medical University, Fuzhou 350209, Fujian, China;Fujian Provincial Institutes of Brain Disorders and Brain Sciences, The First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, Fujian, China;Fujian Provincial Clinical Research Center for Neurological Diseases, The First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, Fujian, China.）

出处： Biomedical and environmental sciences : BES 2024

关键词： Female;Nabothian cyst;Nicotinamide adenine dinucleotide;Risk factor.

摘要： Objective: Little is known about the association between whole-blood nicotinamide adenine dinucleotide (NAD ⁺) levels and nabothian cysts. ...

作者： Zhenyu Yang  ¹, Xiu Shen  ¹, Junyi Jin  ¹, Xiaoyan Jiang  ^{1   2   3}, Wenqi Pan  ⁴, Chenyao Wu  ¹, Dehong Yu  ¹, Ping Li  ¹, Wei Feng  ^{1   2   5}, Yu Chen  ^{1   2   5} （Affiliations ¹ Materdicine Lab, School of Life Sciences, Shanghai University, Shanghai, 200444, P. R. China. ² School of Environmental and Chemical Engineering, Shanghai University, Shanghai, 200444, P. R. China. ³ School of Medicine, Shanghai University, Shanghai, 200444, P. R. China. ⁴ Department of Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, P. R. China. ⁵ Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision, and Brain Health) Wenzhou Institute of Shanghai University, Wenzhou, Zhejiang, 325088, P. R. China.）

出处： Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024

关键词： cyanobacteria;sonoafterglow;sonodynamic therapy ferroptosis;sonosynthesis.

摘要： Photosynthesis, essential for life on earth, sustains diverse processes by providing nutrition in plants and microorganisms. Especially, photosynthesi ...

作者： Yuanyuan Zeng  ¹, Yun Xie  ¹, Daonan Chen  ¹, Ruilan Wang  ¹ （Affiliation ¹ Department of Emergency And Critical Care, Shanghai General Hospital of Nanjing Medical University, Shanghai 201620, China.）

出处： Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 2024

关键词： Euthyroid sick syndrome (ESS);Influencing factors;Prevalence;Prognosis;Sepsis.

摘要： Objective: To evaluate the prevalence of euthyroid sick syndrome (ESS) in sepsis patients and to explore its influencing factors. Methods: In the stud ...

作者： Jun Zhu  ¹, Yingchi Shan  ¹, Yihua Li  ², Xuxu Xu  ³, Xiang Wu  ¹, Yajun Xue  ⁴, Guoyi Gao  ^{5   6} （Affiliations ¹ Department of Neurosurgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201600, China. ² Department of Neurosurgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China. ³ Department of Neurosurgery, Minhang Hospital Fudan University, Shanghai, 201199, China. ⁴ Department of Neurosurgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201600, China. xue_yj@163.com. ⁵ Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100070, China. gao3@sina.com. ⁶ Neurotrauma Laboratory, Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100070, China. gao3@sina.com.）

出处： Intensive care medicine experimental 2024

关键词： Complexity;Intracranial hypertension;Random forest;Traumatic brain injury.

摘要： Background: Treatment and prevention of intracranial hypertension (IH) to minimize secondary brain injury are central to the neurocritical care manage ...

作者： Yanlin Qu  ^{1   2   3}, Guanran Zhang  ^{1   2   3}, Zhenyu Wu  ⁴, Huihuan Luo  ⁴, Renjie Chen  ⁴, Huixun Jia  ^{1   2   3   4}, Xiaodong Sun  ^{1   2   3} （Affiliations ¹ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai, China. ³ National Clinical Research Center for Eye Diseases, Shanghai, China. ⁴ School of Public Health, Fudan University, Shanghai, China.）

出处： Health data science 2024

摘要： Background: The relationship between socioeconomic status (SES) inequity and incident age-related macular degeneration (AMD) remains unclear. We aim t ...

作者： J Z Li  ¹, X B Cai  ², L G Lu  ² （Affiliations ¹ Department of Gastroenterology, Xining Second Hospital, Xining 810006, China. ² Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200080, China.）

出处： Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 2024

关键词： Endoscopic ultrasonography;Liver biopsy;endoscopic ultrasonography-guided liver biopsy.

摘要： Liver biopsy is an important means of clinical diagnosis and treatment of liver diseases, but it is not easily accepted by patients because of its inv ...

作者： Mei Kang^1,2;Hai-peng Li¹;Jia Tang¹;Xin-yu Wang¹;Li-fang Wang³;Guy Baele⁴;Jia-tao Lou⁵;Philippe Lemey⁴;Shuo Su¹1,2 （¹Shanghai Institute of Infectious Disease and Biosecurity, School of Public Health, Fudan University, Shanghai 200030, China;²Clinical Research Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;³National Key Laboratory of Veterinary Public Health Security, College of Veterinary Medicine, China Agricultural University, Beijing, China;⁴Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory for Clinical and Epidemiological Virology, KU Leuven, Leuven, Belgium;⁵Department of Laboratory Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China）

出处： The Lancet Microbe 2024

作者： Greg Petruncio  ¹, Kyung Hyeon Lee  ², Michael Girgis  ³, Zachary Shellnutt  ⁴, Zach Beaulac  ⁴, Jiangdong Xiang  ⁵, Soo Hyeon Lee  ⁶, Xuejun Peng  ⁷, Marie Burdick  ⁸, Schroeder M Noble  ⁹, Yun M Shim  ¹⁰, Mikell Paige  ¹¹ （Affiliations ¹ Department of Chemistry & Biochemistry, George Mason University, 10920 George Mason Circle, Manassas, VA, 20110, United States; Center for Molecular Engineering, George Mason University, 10920 George Mason Circle, Manassas, VA, 20110, United States. Electronic address: gpetrunc@gmu.edu. ² Department of Chemistry & Biochemistry, George Mason University, 10920 George Mason Circle, Manassas, VA, 20110, United States; Center for Molecular Engineering, George Mason University, 10920 George Mason Circle, Manassas, VA, 20110, United States; Bacterial Diseases Branch, Wound Infections Department, Walter Reed Army Institute of Research, 503 Robert Grant Ave, Silver Spring, MD, 20910, United States. ³ Center for Molecular Engineering, George Mason University, 10920 George Mason Circle, Manassas, VA, 20110, United States; Department of Bioengineering, George Mason University, 10920 George Mason Circle, Manassas, VA, 20110, United States. ⁴ Department of Chemistry & Biochemistry, George Mason University, 10920 George Mason Circle, Manassas, VA, 20110, United States. ⁵ Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. ⁶ Bacterial Diseases Branch, Wound Infections Department, Walter Reed Army Institute of Research, 503 Robert Grant Ave, Silver Spring, MD, 20910, United States. ⁷ Bruker Scientific LLC., 101 Daggett Drive, San Jose CA, 95134, United States. ⁸ Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Virginia, P.O. Box 800546, Charlottesville, VA, 22908, United States. ⁹ Bacterial Diseases Branch, Wound Infections Department, Walter Reed Army Institute of Research, 503 Robert Grant Ave, Silver Spring, MD, 20910, United States. Electronic address: schroeder.m.noble.civ@health.mil. ¹⁰ Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Virginia, P.O. Box 800546, Charlottesville, VA, 22908, United States. Electronic address: yss6n@uvahealth.org. ¹¹ Department of Chemistry & Biochemistry, George Mason University, 10920 George Mason Circle, Manassas, VA, 20110, United States; Center for Molecular Engineering, George Mason University, 10920 George Mason Circle, Manassas, VA, 20110, United States. Electronic address: mpaige3@gmu.edu.）

出处： European journal of medicinal chemistry 2024

关键词： Aminopeptidase;Enzyme activation;Leukotriene A(4)hydrolase;Ullmann cross-Coupling.

摘要： Activation of the aminopeptidase (AP) activity of leukotriene A₄ hydrolase (LTA₄H) presents a potential therapeutic strategy for ...

作者： Xiaomin Luo¹;Min Tang¹;Xiaohui Wei¹;Yongde Peng¹CA1 （¹Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Journal of Affective Disorders 2024

摘要： Background The association between magnesium status and sleep quality is unclear. The aim of this study was to determine the relationship between rena ...