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作者: Yihua Bei  1   2, Wenjing Peng  1   2, Juan Zhao  1   2, Chen Chen  1   2, Xuan Deng  3, Feifei Hu  3, Yong Zhou  4, Junjie Xiao  5   6 (Affiliations 1 Institute of Geriatrics (Shanghai University), Affiliated Nantong Hospital of Shanghai University (The Sixth People\'s Hospital of Nantong), School of Medicine, Shanghai University, Nantong, 226011, China. 2 Cardiac Regeneration and Ageing Lab, Institute of Cardiovascular Sciences, Shanghai Engineering Research Center of Organ Repair, School of Life Science, Shanghai University, 333 Nan Chen Road, Shanghai, 200444, China. 3 Clinical Research Institute, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 85 Wu Jin Road, Shanghai, 200080, China. 4 Clinical Research Institute, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 85 Wu Jin Road, Shanghai, 200080, China. yongzhou78214@163.com. 5 Institute of Geriatrics (Shanghai University), Affiliated Nantong Hospital of Shanghai University (The Sixth People\'s Hospital of Nantong), School of Medicine, Shanghai University, Nantong, 226011, China. junjiexiao@shu.edu.cn. 6 Cardiac Regeneration and Ageing Lab, Institute of Cardiovascular Sciences, Shanghai Engineering Research Center of Organ Repair, School of Life Science, Shanghai University, 333 Nan Chen Road, Shanghai, 200444, China. junjiexiao@shu.edu.cn.)

出处: Journal of cardiovascular translational research 2022

关键词: Cardiovascular diseases;Cohort study;Mortality;Physical activity;Risk factors.

摘要: Physical inactivity has been known as an independent risk factor for cardiovascular diseases (CVDs). The "Physical Activity in Cardiovascular Outcomes ...

[外文期刊] ZCL-082, a boron-containing compound, induces apoptosis of non-Hodgkin\'s lymphoma via targeting p90 ribosomal S6 kinase 1/NF-κB signaling pathway.
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作者: Ma, Chunmin1,2;Liu, Meng1;Zhang, Jiong3;Cai, Haiyan1;Wu, Yunzhao1;Zhang, Ying4;Ji, Yanjie1;Shan, Huizhuang1;Zou, Zhihui1;Yang, Li1;Liu, Ligen1;Xu, Hanzhang1;Lei, Hu1;Liu, Chuanxu5;Zhou, Li6;Cao, Yang7;Zhou, Huchen1,3;Wu, Yingli1 (1 Hongqiao International Institute of Medicine, Shanghai Tongren Hospital / Faculty of Basic Medicine, Chemical Biology Division of Shanghai Universities E-Institutes, Key Laboratory of Cell Differentiation and Apoptosis of the Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China 2 Department of Rehabilitation, Shanghai General Hospital, Shanghai Jiao Tong University, No. 100, Haining Road, Shanghai, 200080, China 3 State Key Laboratory of Microbial Metabolism, School of Pharmacy, Shanghai Jiao Tong University, 200240, Shanghai, China 4 Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China 5 Department of Hematology, Xin-Hua Hospital, Shanghai Jiao Tong University School of Medicine, No.197, Ruijin Er Road, Shanghai, China 6 Department of Hematology, Rui-Jin Hospital, Shanghai Jiao Tong University School of Medicine, No.197, Ruijin Er Road, Shanghai, China 7 Department of Hematology, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu Province, 213003, PR China)

出处: Chemico-Biological Interactions 2022 Vol.351

关键词: Boron-containing compound;Lymphoma;NF-κB;RSK1;ZCl-082

摘要: Despite the rapid progress in the diagnosis and treatment, the prognosis of some types of non-Hodgkin\'s lymphoma (NHL), especially those with double- ...

[外文期刊] Lidocaine Ameliorates Psoriasis by Obstructing Pathogenic CGRP Signaling-Mediated Sensory Neuron-Dendritic Cell Communication
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作者: Qianqian Yin  1, Libo Sun  1, Xiaojie Cai  1, Fangzhou Lou  1, Yang Sun  1, Bin Wang  2, Bowen Jiang  2, Lan Bao  2, Xia Li  3, Ningjing Song  4, Sibei Tang  1, Jing Bai  1, Zhikai Wang  1, Yue Wu  1, Hong Zhou  1, Hong Wang  1, Buwei Yu  5, Qifang Li  5, Honglin Wang  6 (Affiliations 1 Shanghai Institute of Immunology, Precision Research Center for Refractory Diseases, Shanghai General Hospital, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China. 2 State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences. 3 Department of Dermatology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai, China. 4 Department of Dermatology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 5 Department of Anesthesiology, Ruijin Hospital and Luwan Branch, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai, China. 6 Shanghai Institute of Immunology, Precision Research Center for Refractory Diseases, Shanghai General Hospital, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China. Electronic address: honglin.wang@sjtu.edu.cn.)

出处: The Journal of investigative dermatology 2022

摘要: Psoriasis is a chronic immune-mediated skin disorder with the nervous system contributing to its pathology. The neurogenic mediators of psoriasis are ...

[外文期刊] Effects of Kinesio taping on skin deformation during knee flexion and extension: a preliminary study
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作者: Fei He #  1   2, Xiaoxuan Wang #  1   3, Menglian Yu  1, Yiyi Chen  2, Bo Yu  2, Jianqiang Lu  4 (Affiliations 1 Key Laboratory of Exercise and Health Science of Ministry of Education, School of Kinesiology, Shanghai University of Sport, No. 200 Hengren Road, Yangpu District, 200438, Shanghai, China. 2 Department of Rehabilitation Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 3 Department of Rehabilitation Medicine, Shanghai Jiao Tong University Affiliated Sixth People\'s Hospital, Shanghai, China. 4 Key Laboratory of Exercise and Health Science of Ministry of Education, School of Kinesiology, Shanghai University of Sport, No. 200 Hengren Road, Yangpu District, 200438, Shanghai, China. lujianqiang@sus.edu.cn.)

出处: BMC musculoskeletal disorders 2022 Vol.23 No.1 P187

关键词: Kinesio taping;Motion capture systems;Skin biomechanics;Skin deformation.

摘要: Background: Kinesio Taping (KT) is proved useful to many musculoskeletal disorders. But the mechanism remains unclear. The kinesio tape works by stick ...

[外文期刊] The possible mechanism of Hippophae fructus oil applied in tympanic membrane repair identified based on network pharmacology and molecular docking
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作者: Juntao Huang  1   2, Bing Mei Teh  3   4   5, Ziqian Xu  6, Zhechen Yuan  1   2, Chongchang Zhou  1   2, Yunbin Shi  1   2, Yi Shen  1   2 (Affiliations 1 Department of Otolaryngology Head and Neck Surgery, Ningbo Medical Center (Ningbo Lihuili Hospital), The Affiliated Lihuili Hospital of Ningbo University, Ningbo, China. 2 School of Medicine, Ningbo University, Ningbo, China. 3 Department of Ear Nose and Throat, Head and Neck Surgery, Eastern Health, Box Hill, Victoria, Australia. 4 Department of Otolaryngology, Head and Neck Surgery, Monash Health, Clayton, Victoria, Australia. 5 Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia. 6 Department of Dermatology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.)

出处: Journal of clinical laboratory analysis 2022 Vol.36 No.1 Pe24157

关键词: Hippophae fructus;molecular docking;network pharmacology;tympanic membrane perforation;wound healing.

摘要: Objective: This study aimed to explore the mechanisms of Hippophae fructus oil (HFO) in the treatment of tympanic membrane (TM) perforation through ne ...

作者: Xu Dai #  1, Yang Hou #  2, Chunxiang Tang  3, Zhigang Lu  4, Chengxing Shen  4, Longjiang Zhang  3, Jiayin Zhang  5 (Affiliations 1 Institute of Diagnostic and Interventional Radiology, Shanghai Jiao Tong University Affiliated Sixth People\'s Hospital, Shanghai, China. 2 Department of Radiology, Shengjing Hospital of China Medical University, Shenyang, China. 3 Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, China. 4 Department of Cardiology, Shanghai Jiao Tong University Affiliated Sixth People\'s Hospital, Shanghai, China. 5 Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.)

出处: Quantitative imaging in medicine and surgery 2022 Vol.12 No.1 P752-765

关键词: Coronary artery disease (CAD);computed tomography (CT);fat attenuation index (FAI);fractional flow reserve (FFR);prognosis.

摘要: Background: To investigate the serial changes of computed tomography (CT) fractional flow reserve (CT-FFR) and fat attenuation index (FAI), and explor ...

作者: Chunjie Jiang  1, Shibiao Wan  2, Peng Hu  3, Yongsheng Li  4, Shengli Li  5 (Affiliations 1 Department of Medicine, Division of Diabetes, Endocrinology and Metabolism, Baylor College of Medicine, Houston, TX, United States. 2 Center for Applied Bioinformatics, St. Jude Children\'s Research Hospital, Memphis, TN, United States. 3 College of Fisheries and Life Science, Shanghai Ocean University, Shanghai, China. 4 Key Laboratory of Tropical Translational Medicine of Ministry of Education, College of Biomedical Information and Engineering, Hainan Medical University, Haikou, China. 5 Precision Research Center for Refractory Diseases, Institute for Clinical Research, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.)

出处: Frontiers in genetics 2022 Vol.13 P845697

关键词: immunology;metabolism;next-generation sequencing;transcription factor;transcriptional regulation.

作者: Tianwei Qian #  1   2   3   4   5   6, Qiaoyun Gong #  1   2   3   4   5, Hangqi Shen  1   2   3   4   5, Caihua Li  7, Gao Wang  6, Xun Xu  1   2   3   4   5, Isabelle Schrauwen  8, Weijun Wang  9   10   11   12   13 (Affiliations 1 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, No. 100 Haining Rd, Shanghai, 200080, China. 2 National Clinical Research Center for Eye Diseases, Shanghai, China. 3 Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai, China. 4 Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China. 5 Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Disease, Shanghai, China. 6 Department of Neurology, Columbia University Medical Center, 630W 168th St, New York, 10032, USA. 7 Genesky Biotechnologies Inc, Shanghai, China. 8 Department of Neurology, Columbia University Medical Center, 630W 168th St, New York, 10032, USA. is2632@cumc.columbia.edu. 9 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, No. 100 Haining Rd, Shanghai, 200080, China. weij719@126.com. 10 National Clinical Research Center for Eye Diseases, Shanghai, China. weij719@126.com. 11 Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai, China. weij719@126.com. 12 Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China. weij719@126.com. 13 Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Disease, Shanghai, China. weij719@126.com.)

出处: BMC ophthalmology 2022 Vol.22 No.1 P69

关键词: Frameshift deletion;Fundus albipunctatus;Missense variants;RDH5 gene.

摘要: Background: The aim of this study is to identify the genetic defects in a Chinese family with fundus albipunctatus. Methods: Complete ophthalmic exami ...

[外文期刊] Higher-order aberrations and their association with axial elongation in highly myopic children and adolescents
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作者: Yupeng Xu  1   2, Junjie Deng  2, Bo Zhang  1, Xian Xu  2, Tianyu Cheng  2, Jingjing Wang  1, Shuyu Xiong  2, Mengli Luan  1, Haidong Zou  1   2, Xiangui He  3   2, Chun Tang  3, Xun Xu  1   2 (Affiliations 1 Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China. 2 Department of Ophthalmology, Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China. 3 Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China xianhezi@163.com tangchuntc@shsyf.com.)

出处: The British journal of ophthalmology 2022

关键词: epidemiology;ocular surface;optics and refraction;public health;visual pathway.

摘要: Background: Vision-dependent mechanisms play a role in myopia progression in childhood. Thus, we investigated the distribution of ocular and corneal h ...

[外文期刊] Qici Sanling Decoction Suppresses Glutamine Consumption and Bladder Cancer Cell Growth through Inhibiting c-Myc Expression
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作者: Weihua Chen  1, Weifeng Wang  2, Jun Zhang  2   3, Guoqiang Liao  2, Jie Bai  2   3, Bo Yang  2, Mingyue Tan  4   5, Hua Gong  2 (Affiliations 1 Department of Urology, Shanghai East Hospital, Tongji University, Shanghai 200120, China. 2 Department of Urology, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai 201318, China. 3 Graduate School, Shanghai University of Traditional Chinese Medicine, Shanghai 201318, China. 4 Department of Urology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. 5 Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.)

出处: Journal of oncology 2022 Vol.2022 P7985468

摘要: Traditional Chinese medicine (TCM) is widely used as an alternative therapy for cancer treatment in China. Glutamine catabolism plays an important rol ...

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