作者： Wenrui Zhang  ^{1   2}, Lu Cao  ³, Jian Yang  ⁴, Shuai Zhang  ⁵, Jianyi Zhao  ^{1   2}, Zhonggang Shi  ^{1   2}, Keman Liao  ¹, Haiwei Wang  ⁶, Binghong Chen  ⁷, Zhongrun Qian  ⁸, Haoping Xu  ³, Linshi Wu  ⁹, Hua Liu  ¹⁰, Hongxiang Wang  ⁵, Chunhui Ma  ¹¹, Yongming Qiu  ¹, Jianwei Ge  ⁴, Jiayi Chen  ³, Yingying Lin  ^{1   2} （Affiliations ¹ Brain Injury Center, Shanghai Institute of Head Trauma and. ² Shanghai Cancer Institute, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ Department of Radiation Oncology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁴ Department of Neurosurgery, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁵ Department of Neurosurgery, Shanghai Changhai Hospital, Naval Medical University, Shanghai, China. ⁶ Fujian Key Laboratory for Prenatal Diagnosis and Birth Defects, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China. ⁷ Department of Neurosurgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China. ⁸ Department of Neurosurgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Anhui, China. ⁹ Department of Biliary-Pancreatic Surgery and. ¹⁰ Department of General Surgery, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ¹¹ Department of Orthopedics, Shanghai General Hospital of Shanghai Jiao Tong University, Shanghai, China.）

出处： The Journal of clinical investigation 2023

关键词： Oncology;Proteases.

摘要： Oxygen and nutrient deprivation are common features of solid tumors. Although abnormal alternative splicing (AS) has been found to be an important dri ...

作者： Lei Tang  ¹, Guo-Tong Xu  ¹, Jing-Fa Zhang  ² （Affiliations ¹ Department of Ophthalmology of Tongji Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China. ² Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University; National Clinical Research Center for Eye Diseases; Shanghai Key Laboratory of Ocular Fundus Diseases; Shanghai Engineering Center for Visual Science and Photomedicine; Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China.）

出处： Neural regeneration research 2023

关键词： Müller cells;anti-inflammation therapy;anti-vascular endothelial growth factor;diabetic retinopathy;hyperreflectivity foci;inflammation;inflammatory cells;inflammatory cytokines;leukostasis;microglia.

摘要： Diabetic retinopathy, characterized as a microangiopathy and neurodegenerative disease, is the leading cause of visual impairment in diabetic patients ...

作者： Chong Chen  ¹, Guangyi Hu, Feng'e Chen, Kun Liu, Suqin Yu, Xun Xu （Affiliation ¹ Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China.）

出处： Retina (Philadelphia, Pa.) 2023

摘要： Carbon fiber microelectrodes and carbon fiber composite minielectrodes (CFM/CFCM) have been generally used for measurements of nitric oxide (NO) conce ...

作者： Shien Shen;Ge Yu;Xingya Guo;Guanzhao Zong;Chuanyang Wang;Jingpiao Bao;Jiahui Chen;Zhiyuan Cheng;Wenqin Xiao;Jie Shen;Weiliang Jiang;Rong Wan （Affiliations ¹ Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 85 Wujin Road, Shanghai, 200080, China. ² Shanghai General Hospital of Nanjing Medical University, Nanjing, China. ³ Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 85 Wujin Road, Shanghai, 200080, China. doctorwanrong1970@126.com. ⁴ Shanghai General Hospital of Nanjing Medical University, Nanjing, China. doctorwanrong1970@126.com.）

出处： Esophagus : official journal of the Japan Esophageal Society 2023

关键词： Follow-up;Gastroesophageal reflux;Medigus Ultrasonic Surgical Endostapler (MUSE);Proton pump inhibitor;Transoral incisionless fundoplication.

摘要： Background: To evaluate the long-term efficacy of transoral incisionless fundoplication (TIF) with Medigus Ultrasonic Surgical Endostapler (MUSE) for ...

作者： Xin Li;Tian-Kui Ma;Min Wang;Xiao-Dan Zhang;Tian-Yan Liu;Yue Liu;Zhao-Hui Huang;Yong-Hong Zhu;Shuang Zhang;Li Yin;Yan-Yan Xu;Hong Ding;Cong Liu;Hang Shi;Qiu-Ling Fan （Affiliations ¹ Department of Nephrology, First Hospital of China Medical University, Shenyang, China. ² Department of Nephrology, Fourth Hospital of China Medical University, Shenyang, China. ³ Department of General Surgery, First Hospital of Harbin Medical University, Harbin, China. ⁴ Department of Intensive Care Unit, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, China. ⁵ Department of Nephrology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Frontiers in pharmacology 2023

关键词： ARAP1;HIF-1α;LncRNA-ARAP1-AS2;PKM2;diabetic kidney disease;fibrosis;glycolysis.

摘要： Objectives: Dimeric pyruvate kinase (PK) M2 (PKM2) plays an important role in promoting the accumulation of hypoxia-inducible factor (HIF)-1α, mediati ...

作者： Yiyang Shu;Fuxiang Ye;Haiyun Liu;Jin Wei;Xiaodong Sun （Affiliations ¹ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. ² National Clinical Research Center for Eye Diseases, Shanghai, China. ³ Shanghai Key Laboratory of Ocular Fundus Disease, Shanghai, China. ⁴ Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China. ⁵ Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China. ⁶ Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁷ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. drliuhaiyun@126.com. ⁸ National Clinical Research Center for Eye Diseases, Shanghai, China. drliuhaiyun@126.com. ⁹ Shanghai Key Laboratory of Ocular Fundus Disease, Shanghai, China. drliuhaiyun@126.com. ¹⁰ Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China. drliuhaiyun@126.com. ¹¹ Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China. drliuhaiyun@126.com.）

出处： BMC ophthalmology 2023

关键词： Age-related macular degeneration;Images marker;Optical coherence tomography;Pigment epithelial detachment;Polypoidal choroidal vasculopathy.

摘要： Background: To determine the predictive value of quantitative morphological parameters for pigment epithelial detachment (PED) of neovascular age-rela ...

作者： Chufeng Gu;Yujie Wang;Yan Jiang;Feiping Xu;Shasha Wang;Rui Liu;Wen Yuan;Nurbiyimu Abudureyimu;Ying Wang;Yulan Lu;Xiaolong Li;Tao Wu;Li Dong;Yuzhong Chen;Bin Wang;Yuncheng Zhang;Wen Bin Wei;Qinghua Qiu;Zhi Zheng;Deng Liu;Jili Chen （Affiliations ¹ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine; National Clinical Research Center for Eye Diseases; Key Laboratory of Ocular Fundus Diseases; Engineering Center for Visual Science and Photomedicine; Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China. ² Department of Ophthalmology, Shibei Hospital of Jing'an District, Shanghai, China. ³ Department of Ophthalmology, Bachu County Traditional Chinese Medicine Hospital of Kashgar, Xinjiang, China. ⁴ Department of Ophthalmology, Bachu Country People's Hospital of Kashgar, Xinjiang, China. ⁵ Department of Ophthalmology, Linfen Community Health Service Center of Jing'an District, Shanghai, China. ⁶ Department of Ophthalmology, Pengpu New Village Community Health Service Center of Jing'an District, Shanghai, China. ⁷ Department of Ophthalmology, Pengpu Town Community Health Service Center of Jing'an District, Shanghai, China. ⁸ Beijing Tongren Eye Center, Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Ophthalmology & Visual Sciences Key Lab, Medical Artificial Intelligence Research and Verification Key Laboratory of the Ministry of Industry and Information Technology, Capital Medical University, Beijing, China. ⁹ Beijing Airdoc Technology Co., Ltd, Beijing, China. ¹⁰ Department of Ophthalmology, Tong Ren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China corneachen@163.com liud11@163.com zzheng88@sjtu.edu.cn qiuqh9@shsmu.edu.cn. ¹¹ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine; National Clinical Research Center for Eye Diseases; Key Laboratory of Ocular Fundus Diseases; Engineering Center for Visual Science and Photomedicine; Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China corneachen@163.com liud11@163.com zzheng88@sjtu.edu.cn qiuqh9@shsmu.edu.cn. ¹² Bachu Country People's Hospital of Kashgar, Xinjiang, China corneachen@163.com liud11@163.com zzheng88@sjtu.edu.cn qiuqh9@shsmu.edu.cn. ¹³ Shanghai No. 3 Rehabilitation Hospital, Shanghai, China. ¹⁴ Department of Ophthalmology, Shibei Hospital of Jing'an District, Shanghai, China corneachen@163.com liud11@163.com zzheng88@sjtu.edu.cn qiuqh9@shsmu.edu.cn.）

出处： The British journal of ophthalmology 2023

关键词： Diagnostic tests/Investigation;Public health;Retina.

摘要： Background/aims: This study evaluates the performance of the Airdoc retinal artificial intelligence system (ARAS) for detecting multiple fundus diseas ...

作者： Wenlu Niu;Leheng Liu;Xiaowan Wu;Tiancheng Mao;Zhixia Dong;Xinjian Wan;Hui Zhou;Jing Wang （Affiliations ¹ Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of Gastroenterology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China. ³ Department of Pathology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Scandinavian journal of gastroenterology 2023

关键词： Reactive hyperplasia;diagnosis;grade intraepithelial neoplasia;magnifying endoscopy;narrow-band imaging.

摘要： Background and purpose: Gastric reactive hyperplasia (RH) is a common benign lesion of the gastric mucosa that can be resolved by conservative treatme ...

作者： Sun, Na;Qiao, Wenli;Xing, Yan;Wang, Taisong;Zhao, Jinhua （¹Department of Nuclear Medicine, Shanghai General Hospital, Shanghai JiaoTong University School of Medicine, 200080, Shanghai, China）

出处： Annals of Hematology 2023

关键词： 18F-FDG;Follicular lymphoma;PET/CT;R-CHOP

摘要： Purpose: The prognostic value of interim 18F-FDG PET/CT (I-PET) for follicular lymphoma (FL) is controversial, and may be related to the lack of stric ...

作者： Zhenzhen Wei;Ziyuan Wang;Qiong Chai;Zan Li;Mengjie Zhang;Yuli Zhang;Lu Zhang;Qingfeng Tang;Huirong Zhu;Hua Sui （Affiliations ¹ Medical Experiment Center, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201803, P.R. China. ² Department of Medical Oncology, Shuguang Hospital, Shanghai 201203, P.R. China. ³ Department of Pathology, Shuguang Hospital, Shanghai 201203, P.R. China. ⁴ Office of Academic Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, P.R. China. ⁵ Department of Integrated Chinese and Western Medicine, The Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital, Zhengzhou, Henan 450008, P.R. China.）

出处： Experimental and therapeutic medicine 2023

关键词： cancer stem cell;cetuximab;colorectal cancer;exosome;resistance.

摘要： The anti-EGFR antibody cetuximab is used as a first-line targeted therapeutic drug in colorectal cancer. It has previously been reported that the effi ...