作者： Yi-Zhe Ren ^{# 1}, Ming-Na Zhao ^{# 1}, Feng-Lin Du ², Lei Wu ¹, Lin Wang ³, Jia-Tao Lou ⁴ （Affiliations ¹ Department of Laboratory Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² School of Life Sciences, Bengbu Medical University, Bengbu, China. ³ Department of Laboratory Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. wanglin987654321@126.com. ⁴ Department of Laboratory Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. loujiatao@sjtu.edu.cn.）

出处： Oncogene 2026

摘要： Bone metastasis is a devastating complication of non-small cell lung cancer (NSCLC), critically impairing patient survival. Nevertheless, the underlyi ...

作者： Qihang Yao ¹, Binbin Cao ², Zihan Guo ³, Chenglin Gong ⁴ （Affiliations ¹ Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of Cardiology, The First Affiliated Hospital of Ningbo University, Key Laboratory of Precision Medicine for Atherosclerotic Diseases of Zhejiang Province, Ningbo, Zhejiang 315010, China. ³ Department of General Surgery, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁴ Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: woosa777@163.com.）

出处： Ecotoxicology and environmental safety 2026

关键词： 6PPD-Q;Ferroptosis;HCC;Progression;ZXDC.

摘要： Tire antioxidant degradation product N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine quinone (6PPD-Q), an emerging environmental pollutant, has bee ...

作者： Shu Li ^{# 1}, Linying An ^{# 1}, Shuai Shao ², Tong Wei ², Yin Tong ¹, Yin Tong ³ （Affiliations ¹ Department of Hematology, Shanghai General HospitalShanghai Jiao Tong University School of Medicine, No. 100 Haining Road, Shanghai, 200080, China. ² Department of Cardiology, Shanghai General Hospital, Shanghai Jiao tong University School of medicine, No.100 Haining Road, Shanghai, 200080, China. ³ Department of Hematology, Shanghai General HospitalShanghai Jiao Tong University School of Medicine, No. 100 Haining Road, Shanghai, 200080, China. 18616909158@163.com.）

出处： Clinical and experimental medicine 2026

关键词： Acute myeloid leukemia;Alternative splicing;Prognosis;SpliceSeq;TCGA.

摘要： Alternative splicing (AS) plays critical roles in acute myeloid leukemia (AML), but the prognostic values of AS events are rarely studied. In this stu ...

作者： Yiou Lei ^{1 2 3}, Jiaqi Yang ^{1 2 3}, Ying Li ^{1 2 3}, Bingqing Xiao ^{1 2 3}, Dongwei Lai ^{2 3}, Qinghua Qiu ⁴ （Affiliations ¹ Xiangya School of Medicine, Central South University, Changsha, PR China. ² Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China. ³ National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, PR China. ⁴ Department of Ophthalmology, Tong Ren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.）

出处： Current eye research 2026

关键词： AMD;anti-VEGF;epimacular brachytherapy;radiotherapy;stereotactic radiotherapy.

摘要： Purpose: Anti-vascular endothelial growth factor (anti-VEGF) drugs have limitations in the treatment of neovascular age-related macular degeneration ( ...

作者： Chunyu Liu ^{# 1}, Chaofeng Tu ^{# 2 3}, Peng Li ^{# 4}, Huan Wu ^{# 5 6 7}, Feng Wan ^{# 8 9}, Yong Lu ^{# 10}, Shuyan Tang ¹, Xin Li ¹¹, Kuokuo Li ^{5 6 7}, Jiaxiong Wang ^{12 13}, Yang Gao ^{5 6 7}, Xinyan Geng ¹, Lanlan Meng ^{2 3}, Dapeng Zhou ¹, Yiling Zhou ¹, Zixue Zhou ¹, Haibin Guo ^{8 9}, Yunxia Cao ^{5 6 7}, Li Jin ¹⁴, Zheng Li ⁴, Xiaojin He ¹⁵, Yue-Qiu Tan ^{16 17}, Qiang Sun ^{18 19 20 21}, Feng Zhang ^{22 23 24} （Affiliations ¹ International Peace Maternity and Child Health Hospital, Shanghai Key Laboratory of Embryo Original Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China. ² Institute of Reproductive and Stem Cell Engineering, NHC Key Laboratory of Human Stem Cell and Reproductive Engineering, Xiangya School of Basic Medical Science, Central South University, Changsha, 410013, China. ³ Clinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive and Genetic Hospital of CITIC-XIANGYA, Changsha, 410205, China. ⁴ Department of Andrology, Center for Men's Health, Institute of Urology, Urologic Medical Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. ⁵ Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China. ⁶ NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei, 230032, China. ⁷ Key Laboratory of Population Health Across Life Cycle, Anhui Medical University, Ministry of Education of the People's Republic of China, Hefei, 230032, China. ⁸ Reproductive Medicine Center, Henan Provincial People's Hospital, Zhengzhou, 450003, China. ⁹ Reproductive Medicine Center, People's Hospital of Zhengzhou University, Zhengzhou, 450003, China. ¹⁰ Institute of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Neuroscience, Chinese Academy of Sciences, Shanghai, 200031, China. ¹¹ Department of Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. ¹² State Key Laboratory of Reproductive Medicine, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, 215008, China. ¹³ Suzhou Municipal Hospital, Suzhou, 215002, China. ¹⁴ State Key Laboratory of Genetics and Development of Complex Phenotypes, Institute of Medical Genetics and Genomics, Fudan University, Shanghai, 200438, China. ¹⁵ Reproductive Medicine Center, Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. hxj0117@126.com. ¹⁶ Institute of Reproductive and Stem Cell Engineering, NHC Key Laboratory of Human Stem Cell and Reproductive Engineering, Xiangya School of Basic Medical Science, Central South University, Changsha, 410013, China. tanyueqiu@csu.edu.cn. ¹⁷ Clinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive and Genetic Hospital of CITIC-XIANGYA, Changsha, 410205, China. tanyueqiu@csu.edu.cn. ¹⁸ Institute of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, State Key Laboratory of Neuroscience, Chinese Academy of Sciences, Shanghai, 200031, China. qsun@ion.ac.cn. ¹⁹ Shanghai Center for Brain Science and Brain-Inspired Technology, Shanghai, 201602, China. qsun@ion.ac.cn. ²⁰ National Key Laboratory of Genetic Evolution and Animal Model, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, 650201, China. qsun@ion.ac.cn. ²¹ University of Chinese Academy of Sciences, Beijing, 101408, China. qsun@ion.ac.cn. ²² International Peace Maternity and Child Health Hospital, Shanghai Key Laboratory of Embryo Original Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China. zhangfeng@fudan.edu.cn. ²³ State Key Laboratory of Genetics and Development of Complex Phenotypes, Institute of Medical Genetics and Genomics, Fudan University, Shanghai, 200438, China. zhangfeng@fudan.edu.cn. ²⁴ The Second Affiliated Hospital, Institute of Biomedical Innovation, Jiangxi Academy of Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China. zhangfeng@fudan.edu.cn.）

出处： Science China. Life sciences 2026

关键词： TFDP3;apoptosis;cynomolgus monkeys;oligoasthenoteratozoospermia;primate-specific gene.

摘要： Primate-specific genes (PSGs), important contributors to the origin of adaptive evolutionary novelties, are abundantly expressed in the testis. Howeve ...

作者： Yuhang Ma ¹, Yi Lin ¹, Xiaoying Ding ¹, Yongde Peng ¹ （Affiliation ¹ Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.）

出处： Endocrinology, diabetes & metabolism 2026

关键词： diabetes mellitus;hypoglycaemic agents;meta‐analysis;metformin;sodium‐glucose transporter 2 inhibitors;systematic review.

摘要： Aims: To compare up-to-date efficacy and safety data of sodium-glucose cotransporter-2 inhibitors (SGLT-2is) versus other metformin-containing oral du ...

作者： Jia Yang ^{# 1}, Yi Zhang ^{# 1}, Qinqin Yu ¹, Xinxing Hu ¹, Qian Luo ¹, Lei Zhang ¹ （Affiliation ¹ Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Quantitative imaging in medicine and surgery 2026

关键词： Cardiac magnetic resonance (CMR);T1 mapping;T2 mapping;feature-tracking (FT);premature ventricular contractions (PVCs).

摘要： Background: Although standard cardiac magnetic resonance (CMR) findings are typically normal in patients with idiopathic premature ventricular contrac ...

作者： Wei Zhou ^{# 1}, Xiao-Bin Liu ^{# 1}, Zhen Du ^{# 2}, Shao-Lin Ma ³, Feng Zhu ⁴ （Affiliations ¹ Department of Critical Care Medicine, Shanghai East Hospital, Tongji University School of Medicine, 150 JiMo Road, Shanghai, 200120, China. ² Department of Cardiovascular Surgery, Shanghai First People's Hospital, Shanghai, 200433, China. ³ Department of Critical Care Medicine, Shanghai East Hospital, Tongji University School of Medicine, 150 JiMo Road, Shanghai, 200120, China. mslin@sohu.com. ⁴ Department of Critical Care Medicine, Shanghai East Hospital, Tongji University School of Medicine, 150 JiMo Road, Shanghai, 200120, China. alexzhujunchi@hotmail.com.）

出处： General thoracic and cardiovascular surgery 2026

关键词： Cardiac surgery;Cardiac valve;Preoperative;Risk assessment.

作者： Jianbo Ni  ¹, Guanhao Su  ¹, Kai Xu  ¹, Xiaoyuan Gong  ¹, Baiwen Li  ¹ （Affiliation ¹ Department of Gastroenterology and Digestive Endoscopy, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Endoscopy 2026

作者： Xin Li ^{#  1}, Chenwang Zhang ^{#  2   3}, Chencheng Yao  ², Xiaobo Wang  ², Liren Jiang  ⁴, Zheng Li  ², Peng Li  ^{2   5}, Rong Wu  ¹ （Affiliations ¹ Department of Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of Andrology, the Center for Men's Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ State Key Lab of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China. ⁴ Department of Pathology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁵ Department of Urology, Ningde Municipal Hospital of Ningde Normal University, Ningde, China.）

出处： Translational andrology and urology 2026

关键词： Johnsen score;Rete testis thickness (RTT);microdissection testicular sperm extraction (micro-TESE).

摘要： Background: Microdissection testicular sperm extraction (micro-TESE) is an important technique for retrieving sperm in cases of non-obstructive azoosp ...