作者： Jaafar Abdul-Aziz Mehrez,^a  ;Xiyu Chen,^a  ;Min Zeng,*^a  ;Jianhua Yang, ^a  ;Nantao Hu, ^a  ;Tao Wang,^a  ;Ruili Liu, ^a  ;Lin Xu,^b  ;Yorexis González-Alfaro^c  and ;Zhi Yang *^a   （* Corresponding authors ^a Key Laboratory of Thin Film and Microfabrication (Ministry of Education), Department of Micro/Nano Electronics, School of Electronics Information and Electrical Engineering, Shanghai Jiao Tong University, Shanghai 200240, People's Republic of China E-mail: minzeng@sjtu.edu.cn, zhiyang@sjtu.edu.cn ^b Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, National Clinical Research Centre for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Centre for Visual Science and Photomedicine, Shanghai 200080, People's Republic of China ^c Centre for Advanced Studies of Cuba, Havana, Cuba）

出处： Physical Chemistry Chemical Physics 2023

摘要： Vertical van der Waals (vdW) heterostructures have shown potential for gas sensing owing to their remarkable sensitivity. However, the optimization pr ...

作者： Lanting Yu  ^{1   2}, Jiawei Lu  ^{1   2}, Ni Xie  ^{1   2}, Lutong Fang  ³, Sumin Chen  ⁴, Ying Wu  ^{1   2}, Xingpeng Wang  ^{1   2}, Baiwen Li  ^{1   2} （Affiliations ¹ Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, China. ² Shanghai Key Laboratory of Pancreatic Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, China. ³ The First Affiliated Hospital of Anhui Medical University, Anhui 230022, China. ⁴ Department of Gastroenterology, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201803, China.）

出处： Journal of Cancer 2023

关键词： DVL2;METTL16;Pancreatic ductal adenocarcinoma;Wnt/β-catenin signaling;m6A.

摘要： Pancreatic cancer is a formidable cause of cancer-related deaths worldwide and has witnessed a more than twofold increase in incidence over the last 2 ...

作者： Weijin Nan  ¹, Yuxi He  ², Sitong Shen  ², Meiliang Wu  ², Shurong Wang  ³, Yan Zhang  ⁴ （Affiliations ¹ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China; Corneal Refraction Department, The Second Hospital of Jilin University, Changchun, 130000, China. ² Corneal Refraction Department, The Second Hospital of Jilin University, Changchun, 130000, China. ³ Department of Ophthalmology, China-Japan Union Hospital of Jilin University, Changchun, 130000, China. ⁴ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China; Corneal Refraction Department, The Second Hospital of Jilin University, Changchun, 130000, China. Electronic address: ahzhangyolanda@163.com.）

出处： Experimental eye research 2023

关键词： Bone morphogenetic protein 4;Corneal neovascularization;Inflammation;Neutrophil extracellular traps;Stalk cells;Tip cells.

摘要： Corneal neovascularization (CNV) can lead to impaired corneal transparency, resulting in vision loss or blindness. The primary pathological mechanism ...

作者： Shuyi Zhou  ¹, Xixi Hou  ², Ling Li  ³, LiHao Guo  ¹, Huili Wang  ⁴, Longfei Mao  ⁵, Leilei Shi  ⁶, Miaomiao Yuan  ⁷ （Affiliations ¹ Precision Research Center for Refractory Diseases in Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China. ² Key Laboratory of Green Chemical Media and Reactions (Ministry of Education), Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan 453007, China. ³ Department of Pharmacology, the Eighth Affiliated Hospital, Sun Yat-sen University, Joint Laboratory of Guangdong-Hong Kong-Macao Universities for Nutritional Metabolism and Precise Prevention and Control of Major Chronic Diseases, Shenzhen, China. ⁴ University of North Carolina Hospitals, 101 Manning Dr, Chapel Hill, Orange County, NC27599, USA. ⁵ Key Laboratory of Green Chemical Media and Reactions (Ministry of Education), Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan 453007, China; College of Basic Medicine and Forensic Medicine, Henan University of Science and Technology, 263 Kaiyuan Road, Luoyang 471003, China. Electronic address: longfeimao1988@163.com. ⁶ Precision Research Center for Refractory Diseases in Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China. Electronic address: leilei.shi@shgh.cn. ⁷ Precision Research Center for Refractory Diseases in Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China. Electronic address: miaomiaoyuan2023@shsmu.edu.cn.）

出处： Bioorganic chemistry 2023

关键词： 1,2,3-triazole;DNA damage;Dolutegravir derivatives;Prostate cancer.

摘要： Prostate cancer (PCa) is the second most frequently diagnosed cancer among men, causing a huge number of deaths each year. Traditional chemotherapy fo ...

作者： Zheng Wang¹;Dan Zhang²;Peng Zhang²;Wenhao Zhou²;Liyuan Hu²;Laishuan Wang²;Guoqiang Cheng³CA1 （¹Department of Neonatology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 201600, Shanghai, China;²Department of Neonatology, Children’s Hospital of Fudan University, 200032, Shanghai, China;³Department of Fujian Key Laboratory of Neonatal Diseases, Xiamen Key Laboratory of Neonatal Diseases, 361000, Fujian, China）

出处： BMC Pediatrics 2023

关键词： Neonatal;Mild;Hypoxic-ischemic encephalopathy;Therapeutic hypothermia

摘要： Background Though there has been an increase in the number of neonates with hypoxic-ischemic encephalopathy (HIE) treated by therapeutic hypothermia ...

作者： Mengxia Chen¹;Yanqiu Weng^1,2;Jingwen Zhang¹;Liyan Gu³;Wenyao Chen^1,2;Mengting Qiao¹;Mengdi Wang¹;Xiaorong Huang⁴;Lan Chen⁵CA1;Lingjuan Zhang^1,2CA2 （¹Education and Scientific Research Department of Clinical Nursing, The First Affiliated Hospital of Naval Medical University, Shanghai, China;²Shanghai Quality Control Center of Geriatric Care, Shanghai, China;³Department of Neurology, No. 905 Hospital of PLA Navy, Shanghai, China;⁴Department of Nursing, Huzhou University, Huzhou, Zhejiang, China;⁵Department of Nursing, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China）

出处： BMC Oral Health 2023

关键词： Nurse;Attitude;Oral hygiene;Geriatric care facilities

摘要： Background The world’s population is getting older. This issue is accompanied by a rise in the number of older people suffering from dementia and dis ...

作者： Shuwei Hu  ¹, Yingdong Zhu  ², Xiaojie Zhao  ³, Rui Li  ³, Guangze Shao  ³, Dongxu Gong  ³, Chencheng Hu  ³, Hongjun Liu  ³, Kexin Xu  ⁴, Chenxi Liu  ³, Minghuan Xu  ³, Zhonghua Zhao  ³, Tao Li  ⁵, Zhigang Hu  ⁶, Mengle Shao  ⁷, Jun- Liu  ⁴, Xinwei Li  ⁸, Huijuan Wu  ³, Jing Li  ⁹, Yanyong Xu  ¹⁰ （Affiliations ¹ School of Basic Medical Sciences, Fudan University Shanghai, Shanghai 200032, China; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH 44272, USA. ² Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH 44272, USA. ³ Department of Pathology, School of Basic Medical Sciences, Fudan University Shanghai, Shanghai 200032, China. ⁴ Department of Nephrology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. ⁵ Department of Hepatobiliary Surgery, Peking University People's Hospital Xizhimen South Street, West District, Beijing 100044, China. ⁶ Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing 210023, China. ⁷ Center for Microbes, Development and Health, CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai 200031, China. ⁸ State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun 130062, China. ⁹ Department of Endocrinology, Beijing Chao-yang Hospital, Capital Medical University, Beijing 100020, China. Electronic address: s-a-sally@163.com. ¹⁰ Key Laboratory of Metabolism and Molecular Medicine of the Ministry of Education, Department of Pathology of School of Basic Medical Sciences, Frontier Innovation Center, Fudan University Shanghai, Shanghai 200032, China; Diabetes, Obesity and Metabolism Research Center, Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH 44272, USA. Electronic address: yanyong_xu@fudan.edu.cn.）

出处： Developmental cell 2023

关键词： HDL metabolism;Lcn2;SR-BI ubiquitination;atherosclerosis.

摘要： High-density lipoprotein (HDL) metabolism is regulated by complex interplay between the scavenger receptor group B type 1 (SR-BI) and multiple signali ...

作者： Ming Zhao  ^{1   2   3}, Zhi Guo  ⁴, Ying-Hua Zou  ⁵, Xiao Li  ⁶, Zhi-Ping Yan  ⁷, Min-Shan Chen  ⁸, Wei-Jun Fan  ⁹, Hai-Liang Li  ¹⁰, Ji-Jin Yang  ¹¹, Xiao-Ming Chen  ¹², Lin-Feng Xu  ¹³, Yue-Wei Zhang  ¹⁴, Kang-Shun Zhu  ¹⁵, Jun-Hui Sun  ¹⁶, Jia-Ping Li  ¹⁷, Yong Jin  ¹⁸, Hai-Peng Yu  ⁴, Feng Duan  ¹⁹, Bin Xiong  ²⁰, Guo-Wen Yin  ²¹, Hai-Lan Lin  ²², Yi-Long Ma  ²³, Hua-Ming Wang  ²⁴, Shan-Zhi Gu  ²⁵, Tong-Guo Si  ⁴, Xiao-Dong Wang  ²⁶, Chang Zhao  ²³, Wen-Chang Yu  ²², Jian-Hai Guo  ²⁶, Jian Zhai  ²⁷, Yong-Hui Huang  ²⁸, Wei-Yu Wang  ²⁹, Hai-Feng Lin  ³⁰, Yang-Kui Gu  ⁹, Jin-Zhang Chen  ³¹, Jian-Peng Wang  ³², Yi-Min Zhang  ³³, Jun-Zhe Yi  ³³, Ning Lyu  ^{9   34   35} （Affiliations ¹ Department of Minimally Invasive Interventional Therapy, Liver Cancer Study and Service Group, Sun Yat-Sen University Cancer Center, Guangzhou, China. drmingzhao@outlook.com. ² State Key Laboratory of Oncology in South China, 651 Dongfeng East Road, Guangzhou, 510060, Guangdong, China. drmingzhao@outlook.com. ³ Collaborative Innovation Center for Cancer Medicine, 651 Dongfeng East Road, Guangzhou, 510060, Guangdong, China. drmingzhao@outlook.com. ⁴ Department of Interventional Therapy, Tianjin Medical University Cancer Institute & Hospital, Tianjin, China. ⁵ Department of Interventional and Vascular Surgery, Peking University First Hospital, Beijing, China. ⁶ Department of Interventional Therapy, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. ⁷ Department of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, China. ⁸ Department of Liver Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, China. ⁹ Department of Minimally Invasive Interventional Therapy, Liver Cancer Study and Service Group, Sun Yat-Sen University Cancer Center, Guangzhou, China. ¹⁰ Department of Radiology, Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, China. ¹¹ Department of Interventional Radiology, Changhai Hospital, Second Military Medical University, Shanghai, China. ¹² Department of Interventional Radiology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China. ¹³ Department of Interventional Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China. ¹⁴ Hepatopancreatbiliary Center, Tsinghua University Affiliated Beijing Tsinghua Changgung Hospital, Beijing, China. ¹⁵ Department of Minimally Invasive Interventional Radiology and Department of Radiology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. ¹⁶ Division of Hepatobiliary and Pancreatic Surgery, Hepatobiliary and Pancreatic Interventional Treatment Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. ¹⁷ Department of Interventional Oncology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China. ¹⁸ The Interventional Therapy Department, The Second Affiliated Hospital of Soochow University, Suzhou, China. ¹⁹ Department of Interventional Radiology, The General Hospital of Chinese People's Liberation Army, Beijing, China. ²⁰ Department of Interventional Radiology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. ²¹ Department of Interventional Radiology, Jiangsu Cancer Hospital and Jiangsu Institute of Cancer Research, The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China. ²² Department of Interventional Oncology, Fujian Medical University Cancer Hospital, Fujian Cancer Hospital, Fuzhou, China. ²³ Department of Interventional Therapy, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, China. ²⁴ Department of Interventional Therapy, The Fifth Medical Center of the Chinese PLA General Hospital, Beijing, China. ²⁵ Department of Interventional Therapy, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, China. ²⁶ Departments of Interventional Oncology, Peking University Cancer Hospital and Institute, Beijing, China. ²⁷ Department of Interventional Radiology, Eastern Hepatobiliary Surgery Hospital, Shanghai, China. ²⁸ Department of Interventional Radiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China. ²⁹ Department of Interventional Oncology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. ³⁰ Department of Medical Oncology, The Second Affiliated Hospital of Hainan Medical University, Haikou, China. ³¹ Department of Infectious Diseases and Hepatology Unit, Nanfang Hospital, Southern Medical University, Guangzhou, China. ³² Department of Oncology, First People's Hospital of Foshan, Foshan Hospital of Sun Yat-Sen University, Foshan, China. ³³ Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China. ³⁴ State Key Laboratory of Oncology in South China, 651 Dongfeng East Road, Guangzhou, 510060, Guangdong, China. ³⁵ Collaborative Innovation Center for Cancer Medicine, 651 Dongfeng East Road, Guangzhou, 510060, Guangdong, China.）

出处： Hepatology international 2023

关键词： Consensus;FOLFOX;Hepatic arterial infusion chemotherapy;Hepatocellular carcinoma.

摘要： Hepatocellular carcinoma (HCC) is one of the most common malignancies and the third leading cause of cancer-related deaths globally. Hepatic arterial ...

作者： Lianhui Sun¹²;Yuan Zhang¹;Boyu Yang³;Sijun Sun¹;Pengshan Zhang¹;Zai Luo¹;Tingting Feng⁴;Zelin Cui⁵;Ting Zhu²;Yuming Li⁶;Zhengjun Qiu¹;Guangjian Fan²CA1;null;Chen Huang¹CA2 （¹Department of Gastrointestinal Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China;²Precision Research Center for Refractory Diseases, Institute for Clinical Research, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China;³Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China;⁴Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China;⁵Department of Laboratory Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China;⁶Department of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China）

出处： Nature Communications 2023

摘要： Cuproptosis, caused by excessively high copper concentrations, is urgently exploited as a potential cancer therapeutic. However, the mechanisms underl ...

作者： Qian-Qian Tang¹;Yuanyuan Wu¹;Qiang Tao¹;Yanan Shen¹;Xiaohu An¹;Di Liu²CA1;null;Zifeng Xu¹CA2 （¹Department of Anesthesiology, the International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, 910 Hengshan Road, Shanghai, China;²Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China）

出处： Neuropsychopharmacology 2023

摘要： The comorbidity of chronic pain and mental dysfunctions such as anxiety disorders has long been recognized, but the underlying mechanisms remained poo ...