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作者: Jinghan Song 1, Xiong Ye 2, Hui Xiao 1 (Affiliations 1 Department of Respiratory and Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: xiaohui771210@163.com. 2 School of Clinical Medicine, Shanghai University of Medicine & Health Sciences, Shanghai, China.)
出处: Critical reviews in oncology/hematology 2025
关键词: Antineoplastic treatment;Cancer screening;Clinical application;Liquid biopsy;Metastasis;Recurrence.
摘要: In recent years, liquid biopsy has gained prominence as an emerging biomarker in cancer research, providing critical insights into tumor biology and m ...
作者: Min Zhang 1 2, Jiali Wu 1 2, Yimin Wang 3, Yidong Wu 1 2, Xiaoling Wan 1 2, Mei Jiang 1 2, Qiyu Bo 1 2, Jieqiong Chen 1 2, Xiaodong Sun 1 2 4 5 (Affiliations 1 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China. 2 National Clinical Research Center for Ophthalmic Diseases, Shanghai, China. 3 Department of Ophthalmology, Zhongshan Hospital, Fudan University, Shanghai, China. 4 Shanghai Key Laboratory of Fundus Diseases, Shanghai, China. 5 Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China.)
出处: Aging cell 2025
关键词: EndMT;VASH1;circSIRT2;miR‐542‐3p;subretinal fibrosis.
摘要: Neovascular age-related macular degeneration (nAMD), characterized by choroidal neovascularization (CNV), is one of the leading causes of severe visua ...
作者:
Qinqin Cai1,2;Qiao Zhao1,2;Qingxia Yang1;Min Zhu1;Fufen Meng1
出处: Experimental Cell Research 2025
关键词: Ku70;Ku86;P300;Diabetic kidney injury;Glomerular endothelial cell
摘要: Endothelial inflammation caused by hyperglycemia contributes to cardiovascular complications in patients with diabetes. Diabetic kidney injury (DKI) i ...
作者: Huibiao Deng 1, Peng Wang 2, Minxing Liu 3 (Affiliations 1 Department of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China. 2 Department of Emergency, The First Affiliated Hospital of Soochow University, No.899, Pinghai Road, Gusu District, Suzhou City, Jiangsu Province, 215031, China. 3 Department of Emergency, The First Affiliated Hospital of Soochow University, No.899, Pinghai Road, Gusu District, Suzhou City, Jiangsu Province, 215031, China. minxingliu0921@163.com.)
出处: Journal of cardiothoracic surgery 2025
关键词: Intensive care unit;Prognostic value;Pulmonary hypertension.
摘要: Background: The impact of pulmonary hypertension (PH) on critically ill patients has not been fully understood. Our objective was to explore the possi ...
作者: Meng-Qi Zhao 1 2 3, Miao-Yan Fan 2 3, Meng-Yan Cui 2 3, Su-Min Chen 1, Jing-Jing Wang 3, Ying-Ying Lu 4 5, Qiao-Li Jiang 6 (Affiliations 1 Department of Gastroenterology, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 800 Huangjiahuayuan Road, Shanghai, 201803, China. 2 Department of Gastroenterology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 201620, China. 3 Shanghai Key Laboratory of Pancreatic Diseases, Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China. 4 Department of Gastroenterology, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 800 Huangjiahuayuan Road, Shanghai, 201803, China. le_voyageur@sjtu.edu.cn. 5 Department of Gastroenterology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 201620, China. le_voyageur@sjtu.edu.cn. 6 Department of Gastroenterology, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 800 Huangjiahuayuan Road, Shanghai, 201803, China. mqzh0547@sjtu.edu.cn.)
出处: Gut pathogens 2025
关键词: Acute pancreatitis;Candida;Fungal diversity;Fungi;Gut microbiota.
摘要: Objective: The gut is involved in the development of acute pancreatitis (AP). Increased focus is being given to the role of gut microbiota in the path ...
作者: Junying Wei 1, Heshan Cao 2, Mingling Peng 1, Yinzhou Zhang 3, Sibei Li 4, Wuhua Ma 5, Yuhui Li 5 (Affiliations 1 First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China. 2 Department of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China. 3 Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China. 4 Department of Anesthesiology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China. 5 Department of Anesthesiology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.)
出处: PloS one 2025
摘要: Background: Ventilator-associated pneumonia (VAP) is a common nosocomial infection in ICU, significantly associated with poor outcomes. However, there ...
作者: Ruqiang Yuan # 1, Mingjing Gao # 2 3, Hu Xu # 4, Qing Liang 1, Lei Qian 1, Yali Wang 1, Houli Zhang 5, Erjiao Qiang 6, Weijing Yun 7 (Affiliations 1 Advanced Institute for Medical Sciences, Dalian Medical University, Dalian, 116044, China. 2 Department of Pharmacy, Dalian Port Hospital, Dalian, 116001, China. 3 College of Pharmacy, Dalian Medical University, Dalian, 116044, China. 4 Wuhu Hospital and Health Science Center, East China Normal University, Shanghai, 200241, China. 5 College of Pharmacy, Dalian Medical University, Dalian, 116044, China. houlizh@163.com. 6 Department of Pathology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, China. qiangerjiao@126.com. 7 Advanced Institute for Medical Sciences, Dalian Medical University, Dalian, 116044, China. yunweijing@dmu.edu.cn.)
出处: BMC cardiovascular disorders 2025
关键词: Calcium influx;Alantolactone;Hypertension;Voltage-gated Calcium Channels.
摘要: Background: The dried root of Inula helenium L., known as Inulae Radix in Mongolian medicine, is a widely used heat-clearing plant drug within the Ast ...
作者: Ying Zhang # 1 2 3, Yan Ma # 1 2, Yu-Ke Ji # 1 2, Yi-Fei Jiang 1 2, Duo Li 1 2, Wan Mu 4, Mu-Di Yao 5, Jin Yao 6 7, Biao Yan 8 (Affiliations 1 The Affiliated Eye Hospital, Nanjing Medical University, Nanjing, 210000, China. 2 The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, 210000, China. 3 Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200080, China. 4 Eye Institute, Department of Ophthalmology, Eye and ENT Hospital, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, 200030, China. 5 Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200080, China. mudiyao@163.com. 6 The Affiliated Eye Hospital, Nanjing Medical University, Nanjing, 210000, China. jinyao1972@126.com. 7 The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, 210000, China. jinyao1972@126.com. 8 Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200080, China. yanbiao@sjtu.edu.cn.)
出处: Cell communication and signaling : CCS 2025
关键词: Ischemic/reperfusion injury;Müller cells;Reactive gliosis;Retinal ganglion cells;tsRNA.
摘要: Ischemic retinopathies are the major causes of blindness, yet effective early-stage treatments remain limited due to an incomplete understanding of th ...
作者: Jiandong Zhou 1, Yunshan Guo 1, Xuan Liu 1, Weijie Yuan 1 (Affiliation 1 Department of Nephrology, Shanghai General Hospital of Nanjing Medical University, Shanghai, China.)
出处: Adipocyte 2025
关键词: Secretory proteins;adipose tissue;bioinformatics;epigenetics;metabolic syndrome.
摘要: The objective of this study was to identify key secretory protein-encoding differentially expressed genes (SP-DEGs) in adipose tissue in female metabo ...
作者: Wei Chen 1, Yuanjun Tang 2, Yachen Si 1, Boxiang Tu 3, Fuchuan Xiao 4, Xiaolu Bian 1, Ying Xu 1, Yingyi Qin 3 (Affiliations 1 Department of Nephrology, Shanghai Changhai Hospital, Shanghai 200433, China. 2 Department of Clinical Pharmacy, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200240, China. 3 Department of Military Health Statistics, Naval Medical University, Shanghai 200433, China. 4 Navy No. 929 Hospital, Shanghai 200433, China.)
出处: Journal of translational internal medicine 2025
关键词: all-cause mortality;chronic kidney disease;life’s essential 8.
摘要: Background and objectives: The association between chronic kidney disease (CKD) and cardiovascular disease has been previously evaluated. This study a ...
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