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[外文期刊] Publisher Correction: Toripalimab or placebo plus chemotherapy as first-line treatment in advanced nasopharyngeal carcinoma: a multicenter randomized phase 3 trial
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作者: Hai-Qiang Mai #  1, Qiu-Yan Chen #  1, Dongping Chen  2, Chaosu Hu  3, Kunyu Yang  4, Jiyu Wen  5, Jingao Li  6, Ying-Rui Shi  7, Feng Jin  8, Ruilian Xu  9, Jianji Pan  10, Shenhong Qu  11, Ping Li  12, Chunhong Hu  13, Yi-Chun Liu  14, Yi Jiang  15, Xia He  16, Hung-Ming Wang  17, Wan-Teck Lim  18, Wangjun Liao  19, Xiaohui He  20, Xiaozhong Chen  21, Zhigang Liu  22, Xianglin Yuan  23, Qi Li  24, Xiaoyan Lin  25, Shanghua Jing  26, Yanju Chen  27, Yin Lu  28, Ching-Yun Hsieh  29, Muh-Hwa Yang  30, Chia-Jui Yen  31, Jens Samol  32   33, Hui Feng  34   35, Sheng Yao  34   35, Patricia Keegan  35, Rui-Hua Xu  36 (Affiliations 1 Department of Nasopharyngeal Carcinoma, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China. 2 Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, China. 3 Fudan University Cancer Center, Shanghai, China. 4 Union Hospital Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. 5 Affiliated Hospital of Guangdong Medical University, Zhanjiang, China. 6 Jiangxi Cancer Hospital, Nanchang, China. 7 Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Changsha, China. 8 Guizhou Cancer Hospital of Guizhou Medical University, Guiyang, China. 9 Shenzhen People\'s Hospital, Shenzhen, China. 10 Fujian Provincial Cancer Hospital, Fuzhou, China. 11 The People\'s Hospital of Guangxi Zhuang Autonomous Region, Nanning, China. 12 West China Hospital of Sichuan University, Chengdu, China. 13 The Second Xiangya Hospital of Central South University, Changsha, China. 14 Taichung Veterans General Hospital, Taichung, Taiwan. 15 Cancer Hospital of Shantou University Medical College, Shantou, China. 16 Jiangsu Cancer Hospital, Nanjing, China. 17 Chang Gung Memorial Hospital, Taoyuan, Taiwan. 18 National Cancer Centre, Singapore City, Singapore. 19 Nanfang Hospital, Guangzhou, China. 20 Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. 21 Zhejiang Cancer Hospital, Hangzhou, China. 22 The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, China. 23 Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. 24 Shanghai General Hospital, Shanghai, China. 25 Fujian Medical University Union Hospital, Fuzhou, China. 26 The Fourth Hospital of Hebei Medical University Hebei Cancer Hospital, Shijiazhuang, China. 27 Hainan General Hospital, Haikou, China. 28 Liuzhou Worker\'s Hospital, Liuzhou, China. 29 China Medical University Hospital, Taichung, Taiwan. 30 Taipei Veterans General Hospital, Taipei, Taiwan. 31 National Cheng Kung University, Tainan, Taiwan. 32 Tan Tock Seng Hospital, Singapore City, Singapore. 33 Johns Hopkins University, Baltimore, MD, USA. 34 Shanghai Junshi Biosciences, Shanghai, China. 35 TopAlliance Biosciences, Rockville, MD, USA. 36 Department of Medical Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China. xurh@sysucc.org.cn.)

出处: Nature medicine 2022

[外文期刊] Decreased preoperative urinary uromodulin as a predictor of acute kidney injury and perioperative kidney dysfunction in patients undergoing cardiac surgery: a prospective cohort study
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作者: Hang Zhang  1, Hong Lang  2, Mengqing Ma  2, Min Yu  3, Hao Chai  1, Yuntao Hu  1, Wen Chen  4, Xin Chen  5 (Affiliations 1 Department of Thoracic and Cardiovascular Surgery, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing 210006, China. 2 Department of Nephrology, Sir Run Run Hospital, Nanjing Medical University, No. 109 Longmian Road, Nanjing 211166, China. 3 Department of Cardiovascular Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 100 Haining Road, Shanghai 200080, China. 4 Department of Thoracic and Cardiovascular Surgery, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing 210006, China. Electronic address: cxacf@163.com. 5 Department of Thoracic and Cardiovascular Surgery, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing 210006, China. Electronic address: stevecx@njmu.edu.cn.)

出处: Clinica chimica acta; international journal of clinical chemistry 2022

关键词: Acute kidney injury;Cardiac surgery;Kidney function;Uromodulin.

摘要: Background: Acute kidney injury (AKI) is a major complication following cardiac surgery that substantially increases mortality. We explored the clinic ...

[外文期刊] Combinatorial targeting of Hippo-STRIPAK and PARP elicits synthetic lethality in gastrointestinal cancers
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作者: Liwei An  1, Zhifa Cao  2, Pingping Nie  2, Hui Zhang  3, Zhenzhu Tong  2, Fan Chen  2, Yang Tang  1, Yi Han  1, Wenjia Wang  3, Zhangting Zhao  3, Qingya Zhao  4, Yuqin Yang  4, Yuanzhi Xu  5, Gemin Fang  6, Lei Shi  7, Huixiong Xu  1, Haiqing Ma  8, Shi Jiao  3, Zhaocai Zhou  3 (Affiliations 1 Department of Medical Ultrasound, Shanghai Tenth People\'s Hospital, Tongji University School of Medicine, Shanghai, China. 2 CAS Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China. 3 State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China. 4 Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 5 Department of Stomatology, Shanghai Tenth People\'s Hospital, Tongji University School of Medicine, Shanghai, China. 6 Institutes of Physical Science and Information Technology, Anhui University, Hefei, China. 7 Department of Biochemistry and Molecular Biology, Tianjin Medical University, Tianjin, China. 8 Department of Oncology, Guangdong Academy of Medical Sciences, Guangzhou, China.)

出处: The Journal of clinical investigation 2022 Pe155468

关键词: Cell Biology;Drug therapy;Gastric cancer;Gastroenterology;Molecular biology.

摘要: The striatin-interacting phosphatase and kinase (STRIPAK) complexes integrate extracellular stimuli to result in intracellular activities. Previously, ...

[外文期刊] Bi-allelic SPATA22 Variants Cause Premature Ovarian Insufficiency and Non-obstructive Azoospermia Due to Meiotic Arrest
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作者: Chencheng Yao #  1   2, Dong Hou #  3, Zhiyong Ji  1   2   4, Dongmei Pang  5, Peng Li  1, Ruhui Tian  1, Yuxiang Zhang  1, Ningjing Ou  1   2   4, Haowei Bai  1, Erlei Zhi  1, Yuhua Huang  1, Yingying Qin  3, Jingpeng Zhao  4, Chenchen Wang  6, Zhi Zhou  2, Ting Guo  3, Zheng Li  1   4 (Affiliations 1 Department of Andrology, Center for Men\'s Health, Department of ART, Institute of Urology, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 School of Life Science and Technology, ShanghaiTech University, Shanghai, China. 3 Center for Reproductive Medicine, Shandong University, National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Key laboratory of Reproductive Endocrinology of Ministry of Education, and Shandong Provincial Clinical Medicine Research Center for Reproductive Health, Jinan, China. 4 State Key Lab of Reproductive Medicine, Nanjing Medical University, Nanjing, China. 5 Jimo Hospital of Traditional Chinese Medicine Affiliated to Shandong University of Traditional Chinese Medicine, Qingdao, China. 6 Shanghai Advanced Research Institute, Stem Cell and Reproductive Biology Laboratory, Chinese Academy of Sciences, Shanghai, China.)

出处: Clinical genetics 2022

关键词: Meiosis;Gene variants;NOA;POI;SPATA22.

摘要: The genetic causes of idiopathic premature ovarian insufficiency (POI) and non-obstructive azoospermia (NOA) remain unclear. We performed whole-exome ...

作者: Wei-Jing Gong1,2,3;Peng Cao1,2,3;Qi-Lin Zhang1,2;Xiao-Yu Han4,5;Shuo-Wen Wang6;Yi-Fei Huang1,2;San-Lan Wu1,2;Qiang Li1,2;Rui Zhang1,2;Shuang-Bing Xu7;Ya-Ni Liu1,2;Shao-Jun Shi1,2;Yu Zhang1,2CA1 (1 Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; 2 Hubei Province Clinical Research Center for Precision Medicine for Critical Illness, Wuhan 430022, China; 3 These authors contributed equally to this work.; 4 Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; 5 Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China; 6 Department of Clinical Pharmacy, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, No. 100 Haining Road, Shanghai 200080, China; 7 Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China)

出处: Translational Oncology 2022 Vol.19 P101393

关键词: Lung adenocarcinoma;Pemetrexed plus platinum;Metabolomics;Prediction model

摘要: Background Pemetrexed plus platinum doublet chemotherapy regimen remains to be the standard first-line treatment for lung adenocarcinoma patients. Ho ...

[外文期刊] Severe eosinophilic asthma in Chinese C-BIOPRED asthma cohort
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作者: Qingling Zhang  1, Xiuhua Fu  2, Changzheng Wang  3, Huahao Shen  4, Lei Zhu  5, Guochao Shi  6, Zhongmin Qiu  7, Zhongguang Wen  8, Wei Gu  9, Wei Luo  1, Lina Zhao  10, Yunqin Chen  10, Sam Lim  10, Chang Xiao  10, Jian Kang  11, Yunhui Zhang  12, Mao Huang  13, Jinfu Xu  14, Kewu Huang  15, Qiang Li  16, Xiangyan Zhang  17, Jianping Zhao  18, Xiaoxia Liu  19, Shenghua Sun  20, Huaping Tang  21, Bei He  22, Shaoxi Cai  23, Ping Chen  24, Chunhua Wei  25, Guangfa Wang  26, Ping Chen  27, Lixin Xie  28, Jiangtao Lin  29, Yuling Tang  30, Zhihai Han  31, Kian Fan Chung  32, Nanshan Zhong  1, C-BIOPRED consortium  1 (Affiliations 1 Department of pulmonary and Critical Care Medicine, Guangzhou Institute of Respiratory Health, National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, State Key Laboratory of Respiratory Diseases, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. 2 Department of Respiratory Medicine, The Affiliated Hospital of Inner Mongolia Medical University, Huhhot, China. 3 Department of Respiratory Medicine, Xinqiao Hospital, Army Military Medical University, Chongqing, China. 4 Department of Respiratory Medicine, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China. 5 Department of Respiratory Medicine, Zhongshan Hospital, Shanghai, China. 6 Department of Respiratory Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. 7 Department of Respiratory Medicine, Shanghai Tongji Hospital, Shanghai, China. 8 Department of Respiratory Medicine, The First Affiliated Hospital of PLA General Hospital, Beijing, China. 9 Department of Respiratory, Nanjing First Hospital, Nanjing Medical University, Nanjing, China. 10 AstraZeneca, Shanghai, China. 11 Department of Respiratory Medicine, The First Hospital of China Medical University, Shenyang, China. 12 Department of Respiratory Medicine, The First People\'s Hospital of Yunnan Province, Kunming, China. 13 Department of Respiratory Medicine, Jiangsu Province Hospital, Nanjing, China. 14 Department of Respiratory Medicine, Shanghai Pulmonary Hospital, Shanghai, China. 15 Department of Respiratory Medicine, Beijing Chao-Yang Hospital, Beijing, China. 16 Department of Respiratory Medicine, Shanghai General Hospital, Shanghai, China. 17 Department of Respiratory Medicine, Guizhou Province People\'s Hospital, Guiyang, China. 18 Department of Respiratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. 19 Department of Respiratory Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing, China. 20 Department of Respiratory Medicine, The Third Xiangya Hospital of Central South University, Changsha, China. 21 Department of Respiratory Medicine, Qingdao Municipal Hospital, Qingdao, China. 22 Department of Respiratory Medicine, Peking University Third Hospital, Beijing, China. 23 Department of Respiratory Medicine, Nanfang Hospital of Southern Medical University, Guangzhou, China. 24 Department of Respiratory Medicine, The General Hospital of Shenyang Military, Shenyang, China. 25 Department of Respiratory Medicine, Weifang Asthma hospital, Weifang, China. 26 Department of Respiratory Medicine, Peking University First Hospital, Beijing, China. 27 Department of Respiratory Medicine, The Second Xiangya Hospital of Central South University, Changsha, China. 28 College of Pulmonary and Critical Care Medicine, Chinese PLA General Hospital, Beijing, China. 29 Department of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China. 30 Department of Respiratory Medicine, The First Hospital of Changsha, Changsha, China. 31 Department of Respiratory Medicine, Navy General Hospital, Beijing, China. 32 National Heart and Lung Institute, Imperial College London, & Royal Brompton & Harefield NHS Foundation Trust, London, SW3, UK.)

出处: Clinical and translational medicine 2022 Vol.12 No.2 Pe710

关键词: blood eosinophil count;cigarette smoking;exacerbations;fractional exhaled nitric oxide;severe asthma.

摘要: Dear Editor, In China, asthma affects 45.7 million adults with a prevalence of 4.2%, 1 while that of severe asthma ranges from 3.4% to 8.3% among a ...

作者: Jiangtao Lin #  1, Wenya Wang #  2, Huaping Tang  3, Jianmin Huo  4, Yuhai Gu  5, Rongyu Liu  6, Ping Chen  7, Yadong Yuan  8, Xiaohong Yang  9, Jianying Xu  10, Dejun Sun  11, Najia Li  12, Shujuan Jiang  13, Yiqiang Chen  14, Changzheng Wang  15, Lan Yang  16, Xiaoju Liu  17, Dong Yang  18, Wei Zhang  19, Zhuochang Chen  20, Qichang Lin  21, Chuntao Liu  22, Jianying Zhou  23, Xin Zhou  24, Chengping Hu  25, Ping Jiang  26, Wei Zhou  27, Jie Zhang  28, Shaoxi Cai  29, Chen Qiu  30, Mao Huang  31, Yijiang Huang  32, Huiguo Liu  33, China Asthma Research Collaboration Network (Affiliations 1 Department of Pulmonary and Critical Care Medicine, National Clinical Research Center of Respiratory Disease, China-Japan Friendship Hospital, Beijing, China. jiangtao_l@263.net. 2 Department of Pulmonary and Critical Care Medicine, National Clinical Research Center of Respiratory Disease, China-Japan Friendship Hospital, Beijing, China. 3 Department of Pulmonary and Critical Care Medicine, Qingdao Municipal Hospital, Qingdao, China. 4 Department of Respiratory Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin, China. 5 Department of Respiratory Medicine, Qinghai Provincial People\'s Hospital, Xi\'ning, China. 6 Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, China. 7 Department of Respiratory Medicine, General Hospital of Northern Theater Command, Shenyang, China. 8 Department of Respiratory Medicine, The Second Hospital of Hebei Medical University, Shijiazhuang, China. 9 Department of Pulmonary and Critical Care Medicine, Xinjiang Uiger Municipal People\'s Hospital, Urumqi, China. 10 Department of Pulmonary and Critical Care Medicine, Shanxi Bethune Hospital, Shanxi, China. 11 Department of Pulmonary and Critical Care Medicine, Inner Mongolia People\'s Hospital, Hohhot, China. 12 Department of Respiratory Medicine, Daqing Oilfield General Hospital, Daqing, China. 13 Department of Pulmonary and Critical Care Medicine, Shandong Provincial Hospital, Jinan, China. 14 Department of Respiratory Medicine, The First Affiliated Hospital of Guangxi Medical University, Guangxi, China. 15 Department of Respiratory Medicine, Xinqiao Hospital of Army Medical University, Chongqing, China. 16 Department of Pulmonary and Critical Care Medicine, First Affiliated Hospital of Xi\'an Jiaotong University, Xi\'an, China. 17 Department of Geriatric Respiration, The First Hospital of Lanzhou University, Lanzhou, China. 18 Department of Respiration, Zhongshan Hospital Fudan University, Shanghai, China. 19 Department of Respiratory Medicine, The First Affiliated Hospital of Nanchang University, Nanchang, China. 20 Department of Respiratory Medicine, Henan Provincial People\'s Hospital, Zhengzhou, China. 21 Department of Respiratory Medicine, The First Affiliated Hospital of Fujian Medical University, Xiamen, China. 22 Department of Respiratory Medicine, West China Hospital, Sichuan University, Chengdu, China. 23 Department of Respiratory Medicine, The First Affiliated Hospital, College of Medicine, Zhejiang University, The First Hospital of Zhejiang Province, Hangzhou, China. 24 Department of Respiratory Medicine, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China. 25 Department of Pulmonary and Critical Care Medicine, Xiangya Hospital Central South University, Changsha, China. 26 Department of Respiratory Medicine, Tianjin First Central Hospital, Tianjin, China. 27 Department of Pulmonary and Critical Care Medicine, General Hospital of Ningxia Medical University, Ningxia, China. 28 Department of Pulmonary and Critical Care Medicine, The Second Hospital of Jilin University, Changchun, China. 29 Department of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern University of Science and Technology, Guangzhou, China. 30 Department of Pulmonary and Critical Care Medicine, Shenzhen People\'s Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, China. 31 Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China. 32 Department of Pulmonary and Critical Care Medicine, Hainan General Hospital, Hainan, China. 33 Department of Respiratory Medicine, Tongji Hospital, Tongji Medical college Huazhong University of Science and Technology, Wuhan, China.)

出处: Allergy, asthma & immunology research 2022 Vol.14 No.1 P85-98

关键词: Asthma;internet-based intervention;outpatient monitoring;patient adherence.

摘要: Purpose: As stated in the Global Initiative for Asthma, there are still some asthmatic patients who have not achieved asthma control. Mobile is a usef ...

[外文期刊] Comparison between spleen and liver stiffness measurements by sound touch elastography for diagnosing cirrhosis at different aminotransferase levels: a prospective multicenter study
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作者: Wei Zhang  1, Jinfeng Wang  1, Runze Linghu  2, Xiaoyan Chen  3, Changfeng Dong  4, Shumei Zhang  5, Hao Han  6, Xinping Ren  7, Xiaopan Zou  8, Jiaojiao Ding  9, Suya Ma  10, Xueping Yang  11, Chunlin Tang  12, Qiyu Zhao  13, Yaning Yao  14, Yuying Cai  15, Linsong Wu  16, Long Liu  17, Jing Dong  18, Ruiqing Du  19, Wanying Jia  20, Yongyan Gao  21, Ruifang Zhang  22, Hongyu Zhou  23, Han Yu  24, Zuyi Mao  25, Rongqin Zheng  26, Ping Liang  27 (Affiliations 1 Department of Ultrasound, Guangdong Key Laboratory of Liver Disease Research, Third Affiliated Hospital of Sun Yat-Sen University, 600 Tianhe Road, Guangzhou, 510630, China. 2 Department of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China. 3 Department of Ultrasound, Xiamen Hospital of Traditional Chinese Medicine, Xiamen, China. 4 Department of Medical Ultrasonics, National Clinical Research Center for Infectious Disease, State Key Discipline of Infectious Disease, Shenzhen Third People\'s Hospital, Second Hospital Affiliated to Southern University of Science and Technology, Shenzhen, China. 5 Department of Ultrasound, Guangzhou Eighth People\'s Hospital, Guangzhou Medical University, Guangzhou, China. 6 Department of Ultrasound, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China. 7 Department of Ultrasound, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China. 8 Department of Ultrasound, Mianyang Center Hospital, Mianyang, China. 9 Department of Abdominal Ultrasound, The First Affiliated Hospital of Xinjiang Medical University, Ürümqi, China. 10 Department of Ultrasound, Ningbo Yinzhou No. 2 Hospital, Ningbo, China. 11 Department of Ultrasound, Beijing Ditan Hospital, Capital Medical University, Beijing, China. 12 Department of Ultrasound, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing, China. 13 Department of Ultrasound, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China. 14 Department of Ultrasound, The First Hospital of Lanzhou University, Lanzhou, China. 15 Ultrasound Imaging Department, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, China. 16 Department of Ultrasound, Fuyang People\'s Hospital, Fuyang, China. 17 Department of Medical Ultrasonography, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 18 Department of Ultrasound, Harbin Medical University Cancer Hospital, Harbin, China. 19 Ultrasonography, Shijiazhuang Fifth Hospital, Shijiazhuang, China. 20 Department of Ultrasound, The Second Affiliated Hospital of Xi\'an Jiaotong University, Xi\'an, China. 21 Ultrasound Department, Third Medical Center of PLA General Hospital, Beijing, China. 22 Department of Ultrasound, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China. 23 Department of Ultrasound, The Third Central Hospital of Tianjin, Tianjin, China. 24 Department of Ultrasound, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. 25 Department of Ultrasound, Yichang Central People\'s Hospital, The First College of Clinical Medical Science, China Three Gorges University, Yichang, China. 26 Department of Ultrasound, Guangdong Key Laboratory of Liver Disease Research, Third Affiliated Hospital of Sun Yat-Sen University, 600 Tianhe Road, Guangzhou, 510630, China. zhengrq@mail.sysu.edu.cn. 27 Department of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China. liangping301@126.com.)

出处: European radiology 2022

关键词: Alanine transaminase;Elasticity imaging techniques;Liver cirrhosis;Spleen;Ultrasonography.

摘要: Objectives: To compare the performance of spleen stiffness measurement (SSM) and liver stiffness measurement (LSM) by sound touch elastography (STE) f ...

作者: Peirong Huang  1   2   3, Siddharth Narendran  1   2   4, Felipe Pereira  1   2   5, Shinichi Fukuda  1   2   6, Yosuke Nagasaka  1   2, Ivana Apicella  1   2, Praveen Yerramothu  1   2, Kenneth M Marion  7, Xiaoyu Cai  1   2, Srinivas R Sadda  7   8, Bradley D Gelfand  1   2   9, Jayakrishna Ambati  1   2   10   11 (Affiliations 1 Center for Advanced Vision Science, University of Virginia School of Medicine, Charlottesville, VA, USA. 2 Department of Ophthalmology, University of Virginia School of Medicine, Charlottesville, VA, USA. 3 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 4 Aravind Eye Care System, Madurai, India. 5 Departamento de Oftalmologia e Ciências Visuais, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil. 6 Department of Ophthalmology, University of Tsukuba, Tsukuba, Ibaraki, Japan. 7 Doheny Eye Institute, Los Angeles, CA, USA. 8 Department of Ophthalmology, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA, USA. 9 Department of Biomedical Engineering, University of Virginia School of Medicine, Charlottesville, VA, USA. 10 Department of Pathology, University of Virginia School of Medicine, Charlottesville, VA, USA. 11 Department of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, Charlottesville, VA, USA.)

出处: Translational vision science & technology 2022 Vol.11 No.3 P13

摘要: Purpose: Subretinal injection (SRI) in mice is widely used in retinal research, yet the learning curve (LC) of this surgically challenging technique i ...

[外文期刊] PTPIP51 inhibits non-small-cell lung cancer by promoting PTEN-mediated EGFR degradation
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作者: Minwei He  1, Xing Wang  2, Wei Chen  1, Jianzhi Zhang  3, Ying Xiong  3, Lulu Cao  1, Liyi Zhang  3, Ning Zhao  1, Yue Yang  4, Lu Wang  5 (Affiliations 1 Department of Immunology, School of Basic Medical Sciences, Peking University Health Science Center, Key Laboratory of Medical Immunology of the Ministry of Public Health, Beijing, China. 2 Department of Thoracic Surgery II, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital and Institute, China; Department of Thoracic Surgery, Shanghai General Hospital, Shanghai, China. 3 Department of Thoracic Surgery II, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital and Institute, China. 4 Department of Thoracic Surgery II, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital and Institute, China. Electronic address: zlyangyue@bjmu.edu.cn. 5 Department of Immunology, School of Basic Medical Sciences, Peking University Health Science Center, Key Laboratory of Medical Immunology of the Ministry of Public Health, Beijing, China. Electronic address: wanglu@bjmu.edu.cn.)

出处: Life sciences 2022 P120293

关键词: EGFR;NSCLC;PTEN;PTPIP51.

摘要: Protein tyrosine phosphatase interacting protein 51 (PTPIP51) interacts with two non-receptor tyrosine phosphatases and induces apoptosis. In the pres ...

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