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作者: Zhicheng Dai  1, Yanan Chen  1, Enjun He  1, Hongjie Wang  1, Weihong Guo  1, Zhenkai Wu  2, Kai Huang  3, Qinghua Zhao  1 (Affiliations 1 Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 Department of Pediatric Orthopaedics, Shanghai Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 3 Department of Orthopedics, Zhabei Central Hospital of Jing'an District, Shanghai, China.)

出处: Bone & joint research 2023

摘要: Aims: Osteoporosis is characterized by decreased trabecular bone volume, and microarchitectural deterioration in the medullary cavity. Interleukin-19 ...

作者: Bing Wei  1, Jiadong Zhao  2, Jun Li  1, Junnan Feng  1, Manman Sun  2, Zhizhong Wang  1, Chao Shi  1, Ke Yang  1, Yue Qin  2, Jing Zhang  2, Jie Ma  1, Hui Dong  3 (Affiliations 1 Department of Molecular Pathology, Henan Key Laboratory of Molecular Pathology, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, Henan, China. 2 Nanjing Shenyou Institute of Genome Research, Nanjing, Jiangsu, China. 3 Department of Gastroenterology, Shanghai Key Laboratory of Pancreatic Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.)

出处: Cancer medicine 2023

关键词: BRCA1;TP53;Chinese;germline variants;lung cancer.

摘要: Backgroud: Multiple studies have identified pathogenic germline variants in cancer susceptibility genes (CSGs) in Chinese lung cancer patients; howeve ...

作者: Ying Xiao;Yu Qian;Chenhao Yang;Haidong Zou (1Department of Ophthalmology, Children’s Hospital of Fudan University, National Children’s Medical Center, 399 Wanyuan Road, 201102, Shanghai, China;2Department of Ophthalmology, Shanghai General Hospital (Shanghai First People’s Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China;3Shanghai Key Laboratory of Fundus Diseases, Shanghai, China;4Shanghai Eye Diseases Prevention & Treatment Center, Shanghai Eye Hospital, Shanghai, China;5National Clinical Research Center for Eye Diseases, Shanghai, China;6Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China)

出处: BMC Ophthalmology 2023

关键词: T1DM children;Lens thickness;Lens power;Myopia

摘要: Background This study compares the ocular biometry with or without myopia in children with type 1 diabetes mellitus (T1DM) and healthy children in Ch ...

作者: Yuying Liu;Lu Liu;Mingming Liu;Xuetong Wang;Chengcheng Jin;Bingbing Ni;Bilian Ke (Affiliations 1 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 National Clinical Research Center for Eye Diseases, Shanghai, China. 3 Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai, China. 4 Shanghai Engineering Center for Visual Science and Photo Medicine, Shanghai, China. 5 Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China. 6 Department of Electronic Engineering, Shanghai Jiao Tong University, Shanghai, China.)

出处: Acta ophthalmologica 2023

关键词: accommodation;augmented reality;choroidal blood perfusion;pupil diameter;three-dimension.

摘要: Purpose: The purpose of the study was to investigate the changes of choroidal blood perfusion in different layers and quadrants and its possible relat ...

作者: Xichen Wan;Songjiao Zhao;Yiqin Dai;Jing Zhang;Yan Shen;Lan Gong;Qihua Le (Affiliations 1 Department of Ophthalmology, Eye, Ear, Nose and Throat Hospital of Fudan University, Fudan, China. 2 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 3 Research Centre, Eye, Ear, Nose and Throat Hospital of Fudan University, Fudan, China. 4 Myopia Key Laboratory of Ministry of Health, Eye, Ear, Nose and Throat Hospital of Fudan University, Fudan, China.)

出处: Cell proliferation 2023

摘要: Our previous finding revealed that WNT16b promoted the proliferation of human limbal epithelial stem cells (hLESCs) through a β-catenin independent pa ...

作者: Xiangui He;Jingjing Wang;Zhuoting Zhu;Kaidi Xiang;Xinzi Zhang;Bo Zhang;Jun Chen;Jinliuxing Yang;Linlin Du;Chunjin Niu;Mei Leng;Jiannan Huang;Kun Liu;Haidong Zou;Mingguang He;Xun Xu (Affiliations 1 Department of Clinical Research, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai Vision Health Center and Shanghai Children Myopia Institute, Shanghai, China. 2 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai Center of Eye Shanghai Key Laboratory of Ocular Fundus Diseases, Engineering Center for Visual Science and Photomedicine, Shanghai, China. 3 State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China. 4 Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia. 5 Division of Ophthalmology, Department of Surgery, University of Melbourne, Melbourne, Victoria, Australia. 6 Department of Ophthalmology Prevention, Changning Center for Disease Control and Prevention, Shanghai, China. 7 Department of Teaching and Research, Changning Institute of Education, Shanghai, China.)

出处: JAMA network open 2023

摘要: Importance: Myopia is a global concern, but effective prevention measures remain limited. Premyopia is a refractive state in which children are at hig ...

作者: Wen Su;Zhanhua Liang;Wei Mao;Ming Shao;Xingyue Hu;Yuncheng Wu;Wenshi Wei;Zhenguo Liu;Kezhong Zhang;Beisha Tang;Shuai Cao;Zhuolun Song;Haibo Chen (Affiliations 1 Department of Neurology, Beijing Hospital, Beijing, 100730, China. 2 National Center of Gerontology, Beijing, 100730, China. 3 Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, 100730, China. 4 Department of Neurology, The First Affiliated Hospital of Dalian Medical University, Dalian, 116011, China. 5 Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, 100032, China. 6 Department of Neurology, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, 510000, China. 7 Department of Neurology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 133000, China. 8 Department of Neurology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. 9 Department of Neurology, Huadong Hospital Affiliated to Fudan University, Shanghai, 20040, China. 10 Department of Neurology, Xinhua Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, 200092, China. 11 Department of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China. 12 Department of Neurology, Xiangya Hospital, Central South University, Changsha, 410008, China. 13 Department of China Drug Development, Lundbeck (Beijing) Pharmaceutical Consulting Co, Ltd., Beijing, 100020, China. 14 Department of Neurology, Beijing Hospital, Beijing, 100730, China. dr_chenhaibo@126.com. 15 National Center of Gerontology, Beijing, 100730, China. dr_chenhaibo@126.com. 16 Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, 100730, China. dr_chenhaibo@126.com.)

出处: Drug safety 2023

摘要: Introduction: Rasagiline is indicated for treating idiopathic Parkinson's disease (PD) as monotherapy and adjunct therapy to levodopa in patients. Obj ...

作者: Xu Dai;Ziting Lan;Runjianya Ling;Yarong Yu;Lihua Yu;Zhigang Lu;Chengxing Shen;Kakuya Kitagawa;Yuehua Li;Wenyi Yang;Jiayin Zhang (Affiliations 1 Institute of Diagnostic and Interventional Radiology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, #600, Yishan Rd, Shanghai, China. 2 Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, #85 Wujin Rd, Shanghai, 200080, China. 3 Department of Cardiology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, #600, Yishan Rd, Shanghai, China. 4 Department of Advanced Diagnostic Imaging, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan. 5 Department of Cardiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, #85 Wujin Rd, Shanghai, 200080, China. wenyi.yang@shgh.cn. 6 Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, #85 Wujin Rd, Shanghai, 200080, China. andrewssmu@msn.com.)

出处: European radiology 2023

关键词: Computed tomography angiography;Cost-benefit analysis;Myocardial ischemia;Myocardial perfusion imaging;Prognosis.

摘要: Objectives: To compare the financial and clinical outcomes of CT myocardial perfusion imaging (CT-MPI) + coronary CT angiography (CCTA)-guided versus ...

作者: Jiecheng Qian;Yankun Guo;Youfa Xu;Xinyu Wang;Jianming Chen;Xin Wu (Affiliations 1 Department of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou, China. 2 Department of Pharmacy, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, China. 3 Department of Pharmacy, Organization Department, Shanghai General Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. 4 Shanghai Wei Er Lab, Shanghai, China. 5 Department of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou, China. chenjm0711@163.com. 6 Shanghai Wei Er Lab, Shanghai, China. chenjm0711@163.com. 7 Department of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou, China. wuxin007@126.com. 8 Shanghai Wei Er Lab, Shanghai, China. wuxin007@126.com. 9 Key Laboratory of Smart Drug Delivery of MOE, School of Pharmacy, Fudan University, Shanghai, China. wuxin007@126.com.)

出处: Drug delivery and translational research 2023

关键词: Composite carrier;Drug delivery;Liposome;Micelle;Nanoformulation.

摘要: Among various nanocarriers, liposomes, and micelles are relatively mature drug delivery systems with the advantages of prolonging drug half-life, redu ...

作者: Bin Han #  1, Xiaoqian Zhang #  1, Ling Wang  1, Weijie Yuan  1 (Affiliation 1 Department of Nephrology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.)

出处: Microbiology spectrum 2023

关键词: IFNγ+ CD4+ T cell;cardiomyopathy;chronic kidney disease;gut microbiota;uremic cardiomyopathy.

摘要: Uremic cardiomyopathy (UCM) correlates with chronic kidney disease (CKD)-induced morbidity and mortality. Gut microbiota has been involved in the path ...

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