作者： Zhengzhe Han¹;Lili Deng²;Shiyan Chen²CA;Huaping Wang²CA;Yinjun Huang³CA （¹Department of Orthopedic Surgery, and Shanghai Institute of Microsurgery on Extremities, Shanghai Sixth People's Hospital , 600 Yishan Road, Shanghai 200233, P.R. China;²State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University , Shanghai 201620, P.R. China;³Department of Trauma Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai, 201600, P.R. China）

出处： Burns & Trauma 2023

关键词： Hydrogel;Mechanical properties;Biocompatibility;Angiogenic effects;Wound healing

摘要： Background Wound healing is a process that requires angiogenesis and antibacterial activities and it remains a challenge for both experimental and cl ...

作者： Xu Quan¹;Ying Xin²;He-Ling Wang³;Yingjie Sun⁴;Chanchan Chen⁵;Jiangying Zhang⁴ （¹Department of Stomatology, Shanghai General Hospital, Shanghai, China;²Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi’an Jiaotong University, Xi’an, Shaanxi, China;³Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, Lørenskog, Norway;⁴Xiangya School of Stomatology, Central South University, Changsha, Hunan, China;⁵Department of Stomatology, Shenzhen Children’s Hospital, Shenzhen, Guangdong, China）

出处： PeerJ 2023

关键词： Sirtuin;Metabolic regulation;Oral cancer

摘要： Sirtuins (SIRTs 1-7) are a group of histone deacetylase enzymes with a wide range of enzyme activities that target a range of cellular proteins in the ...

作者： Haowei Bai¹;Yanwei Sha²;Yueqiu Tan³;Peng Li¹;Yuxiang Zhang¹;Junwei Xu¹;Shuai Xu¹;Zhiyong Ji¹;Xiaobo Wang¹;Wei Chen¹;Jianxiong Zhang¹;Chencheng Yao¹;Zheng Li¹;Erlei Zhi¹ （¹Department of Andrology, Center for Men’s Health, Department of ART, Institute of Urologic Medical Center, Shanghai General Hospital, Shanghai Key Lab of Reproductive Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China;²Department of Andrology, Women and Children’s Hospital, School of Medicine, Xiamen University, Xiamen, Fujian, China;³Institute of Reproductive and Stem Cell Engineering, School of Basic Medical Science, Central South University, Changsha, China）

出处： Frontiers in Endocrinology 2023

关键词： TAF7L;hemizygous variant;oligoasthenoteratozoospermia;ICSI;male infertility

摘要： IntroductionOligoasthenoteratozoospermia (OAT) is a major cause of infertility in males. Only a few pathogenic genes of OAT have been clearly identifi ...

作者： Nengneng Li¹;Nengneng Li²;Shiquan Xu¹;Shiquan Xu²;Shuaishuai Zhang¹;Shuaishuai Zhang²;Qiang Zhu¹;Qiang Zhu²;Xiaole Meng¹;Xiaole Meng²;Wenbin An¹;Wenbin An²;Baoqing Fu¹;Baoqing Fu²;Baoqing Fu³;Mengya Zhong⁴;Yan Yang²;Zeyang Lin⁵;Xueni Liu⁶;Junjie Xia²;Jie Wang¹;Jie Wang²;Tingting You¹;Tingting You²;Changxiu Yan²;Huamei Tang⁷;Guohong Zhuang²;Zhihai Peng¹;Zhihai Peng²;Zhihai Peng⁸ （¹Department of Organ Transplantation, Xiang’an Hospital, Xiamen University, Xiamen, Fujian, China;²Fujian Provincial Key Laboratory of Organ and Tissue Regeneration, Organ Transplantation Institute of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China;³Department of Laboratory Medicine, Xiang’an Hospital, Xiamen University, Xiamen, Fujian, China;⁴Cancer Research Center, School of Medicine, Xiamen University, Xiamen, Fujian, China;⁵Department of Pathology, Zhongshan Hospital, Xiamen University, Xiamen, Fujian, China;⁶Department of General Surgery, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China;⁷Department of Pathology, Xiang’an Hospital, School of Medicine, Xiamen University, Xiamen, Fujian, China;⁸Organ Transplantation Clinical Medical Center of Xiamen University, Xiamen, Fujian, China）

出处： Frontiers in Immunology 2023

关键词： inflammatory bowel disease;intestinal microbiota;Musashi2;group 3 innate lymphoid cells;Lactobacillaceae

摘要： BackgroundThe etiology and pathogenesis of inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn’s disease (CD), are generally ...

作者： Shengli Li¹²;Li Yuan¹³⁴;Zhi-Yuan Xu¹³⁴;Jing-Li Xu⁵;Gui-Ping Chen⁶;Xiaoqing Guan¹;Guang-Zhao Pan¹;Can Hu⁵;Jinyun Dong¹;Yi-An Du¹³⁴;Li-Tao Yang¹³⁴;Mao-Wei Ni¹;Rui-Bin Jiang¹;Xiu Zhu¹;Hang Lv⁷;Han-Dong Xu⁵;Sheng-Jie Zhang¹;Jiang-Jiang Qin¹³⁴CA1;Xiang-Dong Cheng¹³⁴CA2 （¹Department of Gastric Surgery, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institutes of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, 310022, China;²Precision Research Center for Refractory Diseases, Institute for Clinical Research, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China;³Zhejiang Provincial Research Center for Upper Gastrointestinal Tract Cancer, Zhejiang Cancer Hospital, Hangzhou, 310022, China;⁴Zhejiang Key Lab of Prevention, Diagnosis and Therapy of Upper Gastrointestinal Cancer, Zhejiang Cancer Hospital, Hangzhou, 310022, China;⁵First Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, 310053, China;⁶Department of Gastrointestinal Surgery, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310006, China;⁷Biological Sample Bank, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310006, China）

出处： Nature Communications 2023

摘要： The incidence of adenocarcinoma of the esophagogastric junction (AEG) has been rapidly increasing in recent decades, but its molecular alterations and ...

作者： Renyuan Wang  ¹, Chang Jiang  ², Zhaoyi Wu  ³, Zhe Wang  ², Ying Peng  ¹, Zhuoxuan Li  ¹, Zhiyang Zhang  ², Haodong Lin  ⁴, Zixian Chen  ⁵ （Affiliations ¹ Trauma center, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, China. ² Department of Orthopedics, Shanghai Zhongshan Hospital, Fudan University, Shanghai, 200080, China. ³ Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. ⁴ Trauma center, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, China. Electronic address: haodonglin@hotmail.com. ⁵ Department of Orthopedics, Shanghai Zhongshan Hospital, Fudan University, Shanghai, 200080, China. Electronic address: chen.zixian@zs-hospital.sh.cn.）

出处： The journal of pain 2023

关键词： Fecal microbiota transplantation;Gut microbiota;Microbiota community;Pain-related behaviors;Postmenopausal allodynia.

摘要： Higher sensitivity to pain is a common clinical symptom in postmenopausal females. The gut microbiota (GM) has recently been identified as participati ...

作者： Qingnan Zhao¹²³;Jiemiao Hu³;Lingyuan Kong³;Shan Jiang⁴;Xiangjun Tian⁵;Jing Wang⁵;Rintaro Hashizume⁶;Zhiliang Jia³;Natalie Wall Fowlkes⁷;Jun Yan⁸;Xueqing Xia³;Sofia F. Yi³;Long Hoang Dao³;David Masopust⁹;Amy B. Heimberger⁵;Shulin Li³CA1 （¹Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200020, China;²Shanghai Key Laboratory of Pancreatic Disease, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China;³Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA;⁴Uaub Institute for Research on Alzheimer’s Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, 77030, USA;⁵Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA;⁶Department of Neurological Surgery, Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA;⁷Department of Veterinary Medicine & Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA;⁸Beijing Institute of Brain Disorders, Capital Medical University, Beijing, 100069, China;⁹Department of Microbiology, Center for Immunology, University of Minnesota, Minneapolis, MN, 55455, USA）

出处： Nature Communications 2023

摘要： Although tissue-resident memory T (T_RM) cells specific for previously encountered pathogens have been characterized, the induction and recr ...

作者： Senlin Lin ^{#  1}, Bijun Zhu ^{#  2}, Ting Wang  ³, Hong Wang  ³, Xian Xu  ², Shanshan Wang  ², Yao Yin  ⁴, Zhaoyu Xiang  ², Yu Qian  ², Zhang Zhang  ², Lipu Cui  ², Haidong Zou  ^{5   2}, Xiangui He  ⁵, Jianfeng Zhu  ⁵, Yingyan Ma  ^{5   2} （Affiliations ¹ Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China. ² Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Fundus Diseases, National Clinical Research Center for Eye Diseases, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China. ³ Department of Preventive Ophthalmology, Yangpu District Kongjiang Hospital, Shanghai, China. ⁴ Department of Ophthalmology, Fengcheng Hospital, Shanghai, China. ⁵ Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China mYy_29@163.com jfzhu1974@hotmail.com xianhezi@163.com zouhaidong@sjtu.edu.cn.）

出处： The British journal of ophthalmology 2023

关键词： Epidemiology;Optics and Refraction;Public health.

摘要： Background/aims: We aim to explore the effect of sympathetic nervous system (SNS) on choroid thickness (ChT) and axial length (AL). Methods: Students ...

作者： Zhaohui Ni  ¹, Renhua Lu  ², Xudong Xu  ³, Xueyan Bian  ⁴, Zhihong Zhou  ⁵, Junwei Yang  ⁶, Qun Luo  ⁷, Menghua Chen  ⁸, Chaosheng Chen  ⁹, Xiuli Sun  ¹⁰, Lei Yu  ¹¹, Qiang He  ¹², Hong Jiang  ¹³, Weijie Yuan  ¹⁴, Yi Li  ¹⁵, Rong Zhou  ¹⁶, Jianqin Wang  ¹⁷, Xinzhou Zhang  ¹⁸, Li Zuo  ¹⁹, Xiangwen Meng  ²⁰, Zhiren Chang  ²¹, June Zhao  ²², Peter Wessman  ²³, Peng Xiang  ²⁰; DIALIZE China Study Group （Affiliations ¹ Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: profnizh@126.com. ² Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ Central Hospital of Minhang District, Shanghai, China. ⁴ Ningbo First Hospital, Ningbo, China. ⁵ The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, China. ⁶ The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China. ⁷ Ningbo Huamei Hospital, University of Chinese Academy of Sciences, Ningbo, China. ⁸ General Hospital of Ningxia Medical University, Yinchuan, China. ⁹ The First Affiliated Hospital of Wenzhou College, Wenzhou, China. ¹⁰ Baotou City Central Hospital, Baotou, China. ¹¹ Inner Mongolia People's Hospital, Hohhot, China. ¹² Zhejiang Traditional Chinese Medicine Hospital, Hangzhou, China. ¹³ People's Hospital of Xinjiang Uygur Autonomous Region, Xinjiang, China. ¹⁴ Shanghai General Hospital, Shanghai, China. ¹⁵ Dongguan People's Hospital, Dongguan, China. ¹⁶ Shanghai Yangpu District Central Hospital, Shanghai, China. ¹⁷ Lanzhou University Second Hospital, Lanzhou, China. ¹⁸ Shenzhen People's Hospital, Shenzhen, China. ¹⁹ Peking University People's Hospital, Beijing, China. ²⁰ Global R&D (China), AstraZeneca, Shanghai, China. ²¹ Global R&D (China), AstraZeneca, Beijing, China. ²² BioPharmaceuticals Clinical, AstraZeneca R&D, Gaithersburg, Maryland. ²³ BioPharmaceuticals Clinical, AstraZeneca R&D, Gothenburg, Sweden.）

出处： Clinical therapeutics 2023

关键词： DIALIZE;dialysis;hyperkalemia;sodium zirconium cyclosilicate.

摘要： Purpose: The DIALIZE China study (Reduce Incidence of Pre-Dialysis Hyperkalaemia With Sodium Zirconium Cyclosilicate in Chinese Subjects) (NCT04217590 ...

作者： Desheng Chen  ¹, Yichao Lou  ¹, Jing Lu  ¹, Xuhui Fan  ², Qi Zhu  ¹, Hongcheng Sun  ¹ （Affiliations ¹ Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. ² Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.）

出处： International journal of molecular sciences 2023

关键词： TMEM201;hepatocellular carcinoma;immune landscape;prognosis;transmembrane protein.

摘要： Aberrant transmembrane protein (TMEM) expression is implicated in tumor progression, but its functional role in hepatocellular carcinoma (HCC) is uncl ...