作者： Hanjun Li  ¹, Jing Lu  ², Shudan Tan  ³, Ting Jiang  ², Xin He  ⁴, Wen Qiao  ⁵, Cegui Hu  ⁶, Sumiya Dalangood  ⁵, Jinzhong Lin  ³, Jun Gui  ⁷ （Affiliations ¹ Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. ² Shanghai RNACure Biopharma Co., Ltd, Shanghai, China. ³ School of Life Sciences, Fudan University, Shanghai, China. ⁴ Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. ⁵ Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, China. ⁶ School of Medicine, Shanghai Jiao Tong University, China. ⁷ Shanghai Jiao Tong University, Shanghai, China.）

出处： Cancer immunology research 2025

摘要： Local immunotherapy stimulates immune responses against tumors while avoiding adverse effects associated with systemic administration. However, curren ...

作者： Yiwei Wang ^{#  1}, Yang Liu ^{#  1}, Xuezeng ^{#  1}, Mengen Zhai  ¹, Xin Meng  ², Ping Jin  ¹, Fanglin Lu  ³, Jian Yang  ⁴ （Affiliations ¹ Department of Cardiovascular Surgery, Xijing Hospital, Air Force Medical University, 127 Changle West Road, Xi'an, 710032, Shaanxi, China. ² Department of Ultrasound Medicine, Xijing Hospital, Air Force Medical University, Xi'an, 710032, Shaanxi, China. ³ Department of Cardiovascular Surgery, Shanghai General Hospital, Shanghai Jiaotong University, 100 Haining Road, Shanghai, 201620, China. drlufanglin@yeah.net. ⁴ Department of Cardiovascular Surgery, Xijing Hospital, Air Force Medical University, 127 Changle West Road, Xi'an, 710032, Shaanxi, China. yangjian1212@hotmail.com.）

出处： Cardiovascular drugs and therapy 2025

关键词： Hospitalization;Severe tricuspid regurgitation;TRI-SCORE;Totally thoracoscopic beating-heart tricuspid valve surgery;Transcatheter tricuspid valve replacement.

摘要： Purpose: Totally thoracoscopic and beating-heart techniques used in tricuspid valve surgery (TTC-TVS) show favorable outcomes. Transcatheter tricuspid ...

作者： Yi Zhang ^{#  1   2}, Kaisai Tian ^{#  2   3}, Liying Zheng ^{#  2   3}, Gaohan Zhu  ^{1   2}, Runyu Zhao  ^{2   3}, Enhui Zhou  ², Xiaocheng Xue  ², Shuixian Huang  ², Xiaoping Chen  ⁴, Baoji Hu  ^{5   6}, Wenhao Yao  ⁷ （Affiliations ¹ School of Gongli Hospital Medical Technology, University of Shanghai for Science and Technology, Shanghai, 200093, China. ² Department of Otorhinolaryngology Head and Neck Surgery, Gongli Hospital of Shanghai Pudong New Area, 219 Miao Pu Road, Shanghai, 200135, China. ³ Postgraduate Training Base at Shanghai Gongli Hospital, Ningxia Medical University, Shanghai, 200135, China. ⁴ Department of Otorhinolaryngology Head and Neck Surgery, Gongli Hospital of Shanghai Pudong New Area, 219 Miao Pu Road, Shanghai, 200135, China. chen_xp2000@163.com. ⁵ School of Gongli Hospital Medical Technology, University of Shanghai for Science and Technology, Shanghai, 200093, China. selfconfidence2005@sina.com. ⁶ Department of Anesthesiology, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, 2800 Gongwei Rd. Pudong New District, Shanghai, 201399, China. selfconfidence2005@sina.com. ⁷ Department of Otolaryngology Head and Neck Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. wenhao.yao@hotmail.com.）

出处： European journal of medical research 2025

关键词： EMT;HPV11 E6/E7;JAK2/STAT3;Nasal hyperplastic diseases;Nasal inverted papilloma.

摘要： Objectives: Nasal mucosal epithelial hyperplasia can cause nasal hyperplastic diseases, more studies have confirmed that different subtypes of HPV inf ...

作者： Dandan Zhao  ¹, Huimin Li  ², Yongdi Lin  ², Lizhen Liu  ³, Lina Xu  ², Dan Zhang  ⁴, Yu Fu  ², Jiang Hong  ², Congliang Miao  ⁵ （Affiliations ¹ Department of Internal and Emergency Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China; Department of Emergency Medicine, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, China. ² Department of Internal and Emergency Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. ³ Department of Pediatrics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. ⁴ Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201800, China. ⁵ Department of Internal and Emergency Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. Electronic address: mcl15917908206@163.com.）

出处： Heart & lung : the journal of critical care 2025

关键词： B-type natriuretic peptide;Cardiac troponin I;Mortality;Prognostic value;Sepsis.

摘要： Background: Sepsis is a global health challenge with high mortality rates. It demands timely risk identification and biomarker-based strategies to opt ...

作者： Lin-Yi Shen  ¹, Li Sun  ², Wei-Xing Li  ¹, Qian-Ru Li  ¹, Yi-Xin Wen  ³, Yi-Wen Hu  ², Yang Sun  ¹, Ji-Wu Chen  ⁴, Hong-Yun Li  ⁵ （Affiliations ¹ Sports Medicine Institution of Fudan University; Department of Sports Medicine and Arthroscopy Surgery, Huashan Hospital, Fudan University, Shanghai, China, 200040. ² Department of Radiology and Institute of Medical Functional and Molecular Imaging, Huashan Hospital, Fudan University, Shanghai, China, 200040. ³ Department of Orthopedics, Wuhan Fifth Hospital, Jianghan University, Wuhan, China, 430050. ⁴ Department of Sports Medicine, Shanghai General Hospital, Shanghai Jiao Tong University; School of Medicine, Shanghai Jiao Tong University, Shanghai, China, 200080. ⁵ Sports Medicine Institution of Fudan University; Department of Sports Medicine and Arthroscopy Surgery, Huashan Hospital, Fudan University, Shanghai, China, 200040. Electronic address: lieaoon@126.com.）

出处： Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association 2025

摘要： Purpose: To explore the healing status of interportal capsulotomies without repair after arthroscopy in patients with femoroacetabular impingement syn ...

作者： Gayathri Swaminathan  ¹, Yu-Chu Lin  ¹, Jianbo Ni  ², Asna Khalid  ¹, Cheng-Yu Tsai  ¹, Ying Ding  ³, Na Bo  ³, Judy-April Murayi  ⁴, Thottala Jayaraman  ⁵, Ronald Poropatich  ⁶, Rita Bottino  ⁷, Georgios I Papachristou  ⁸, Sunil G Sheth  ⁹, Li Wen  ¹⁰, Monique T Barakat  ¹¹, Adam R Frymoyer  ¹², Mang Yu  ¹³, Sohail Z Husain  ¹⁴ （Affiliations ¹ Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Stanford University, School of Medicine, Stanford, CA, USA. ² Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Stanford University, School of Medicine, Stanford, CA, USA; Department of Gastroenterology and Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ Department of Biostatistics, University of Pittsburgh, Pittsburgh, PA, USA. ⁴ Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Nationwide Children's Hospital, Columbus, OH, USA. ⁵ Department of Oral and Craniofacial Sciences, School of Dental Medicine, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA. ⁶ University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA. ⁷ Imagine Islet Center, Imagine Pharma, 1401 Forbes Avenue, Pittsburgh, PA, USA. ⁸ The Ohio State University Wexner Medical Center, Columbus, OH, USA. ⁹ Beth Israel Deaconess Medical Center, Boston, MA, USA. ¹⁰ Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China. ¹¹ Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Stanford University, School of Medicine, Stanford, CA, USA; Division of Gastroenterology and Hepatology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA. ¹² Division of Neonatology, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA. ¹³ Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Stanford University, School of Medicine, Stanford, CA, USA. Electronic address: myu2045@gmail.com. ¹⁴ Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Stanford University, School of Medicine, Stanford, CA, USA. Electronic address: sohail.husain@stanford.edu.）

出处： Pancreatology : official journal of the International Association of Pancreatology (IAP) ... 2025

关键词： Diclofenac;Pharmacokinetics;Post-ERCP pancreatitis;Rectal.

摘要： Objective: Acute pancreatitis is a frequent, burdensome adverse event of endoscopic retrograde cholangiography (ERCP). Rectal nonsteroidal anti-inflam ...

作者： Hui Wang¹;Zijian Wang¹;Jin Ma²;Jian Chen³;Hong Li¹;Weiju Hao¹;Qingyuan Bi¹;Shuning Xiao¹;Jinchen Fan¹CA1;Guisheng Li^1,2 （¹School of Materials and Chemistry, University of Shanghai for Science and Technology, Shanghai 200093, China;²Department of Chemistry, Shanghai Normal University, 100 Guilin Rd., Shanghai 200234, China;³Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, Shanghai 200080, China）

出处： Journal of Colloid and Interface Science 2025

摘要： As a kind of promising oxygen evolution reaction (OER) catalysts, metal–organic frameworks (MOF) are often constrained by their inherent poor electroc ...

作者： Xiao-Yu Wu^1,2;Shi Peng^1,2;Xin-Tao Li^3,2;Song-Wen Chen¹;Yong Wei¹;Yu-Tong Ye¹;Chang-Zuan Zhou¹;Zi-Kan Zhong¹;Long-Zhe Gao¹;Chen-Yang Jin¹;De-Ping Kong⁴;Shao-Wen Liu¹CA1;Gen-Qing Zhou¹CA2 （¹Department of Cardiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200000, China;²These authors contributed equally to this work.;³Department of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou 215006, China;⁴Precision Research Center for Refractory Diseases, Institute for Clinical Research, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200000, China）

出处： Biochimica et Biophysica Acta - Molecular Basis of Disease 2025

关键词： PFKP;Hypertrophy;Myocyte, cardiac;EIF2S2;Protein synthesis

摘要： Metabolic reprogramming precedes most alterations during pathological cardiac hypertrophy and heart failure (HF). Recent studies have revealed that Ph ...

作者： Kainan Guo¹;Kangkang Ou¹CA1;Md All Amin Newton¹;Jun Zhang¹;Hui Xu²;Jinyi Li¹;Binjie Xin¹CA2;Yinjun Huang³CA3 （¹School of Textiles and Fashion, Shanghai University of Engineering Science, Shanghai 201620, PR China;²Henan Key Laboratory of Medical and Protective Products, Xinxiang 453400, PR China;³Department of Trauma Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201600, PR China）

出处： Journal of Colloid and Interface Science 2025

摘要： Chronic wounds often produce a significant volume of exudate, posing a substantial obstacle to healing. Consequently, there is a pressing demand for a ...

作者： Zhong Chen^1,2;Da-Wei Geng²;Tang-Bo Yuan²;Chen Yu²;Da-Wei Cai²;Yong Yin³CA1;Qiang Shen¹CA2 （¹Department of Orthopaedics, Shanghai General Hospital of Nanjing Medical University, Shanghai, China;²Department of Orthopaedics, Sir Run Run Hospital, Nanjing Medical University, Nanjing, China;³Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China）

出处： Bioorganic & Medicinal Chemistry Letters 2025

摘要： Novel N-substituent diphenylamine derivatives as tubulin inhibitors targeting colchicine-binding site have been designed based on structural simplific ...