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作者: Zhengzhe Han1;Lili Deng2;Shiyan Chen2CA;Huaping Wang2CA;Yinjun Huang3CA1Department of Orthopedic Surgery, and Shanghai Institute of Microsurgery on Extremities, Shanghai Sixth People's Hospital , 600 Yishan Road, Shanghai 200233, P.R. China;2State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University , Shanghai 201620, P.R. China;3Department of Trauma Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai, 201600, P.R. China)

出处: Burns & Trauma 2023

关键词: Hydrogel;Mechanical properties;Biocompatibility;Angiogenic effects;Wound healing

摘要: Background Wound healing is a process that requires angiogenesis and antibacterial activities and it remains a challenge for both experimental and cl ...

作者: Xu Quan1;Ying Xin2;He-Ling Wang3;Yingjie Sun4;Chanchan Chen5;Jiangying Zhang41Department of Stomatology, Shanghai General Hospital, Shanghai, China;2Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi’an Jiaotong University, Xi’an, Shaanxi, China;3Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, Lørenskog, Norway;4Xiangya School of Stomatology, Central South University, Changsha, Hunan, China;5Department of Stomatology, Shenzhen Children’s Hospital, Shenzhen, Guangdong, China)

出处: PeerJ 2023

关键词: Sirtuin;Metabolic regulation;Oral cancer

摘要: Sirtuins (SIRTs 1-7) are a group of histone deacetylase enzymes with a wide range of enzyme activities that target a range of cellular proteins in the ...

作者: Haowei Bai1;Yanwei Sha2;Yueqiu Tan3;Peng Li1;Yuxiang Zhang1;Junwei Xu1;Shuai Xu1;Zhiyong Ji1;Xiaobo Wang1;Wei Chen1;Jianxiong Zhang1;Chencheng Yao1;Zheng Li1;Erlei Zhi11Department of Andrology, Center for Men’s Health, Department of ART, Institute of Urologic Medical Center, Shanghai General Hospital, Shanghai Key Lab of Reproductive Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China;2Department of Andrology, Women and Children’s Hospital, School of Medicine, Xiamen University, Xiamen, Fujian, China;3Institute of Reproductive and Stem Cell Engineering, School of Basic Medical Science, Central South University, Changsha, China)

出处: Frontiers in Endocrinology 2023

关键词: TAF7L;hemizygous variant;oligoasthenoteratozoospermia;ICSI;male infertility

摘要: IntroductionOligoasthenoteratozoospermia (OAT) is a major cause of infertility in males. Only a few pathogenic genes of OAT have been clearly identifi ...

作者: Nengneng Li1;Nengneng Li2;Shiquan Xu1;Shiquan Xu2;Shuaishuai Zhang1;Shuaishuai Zhang2;Qiang Zhu1;Qiang Zhu2;Xiaole Meng1;Xiaole Meng2;Wenbin An1;Wenbin An2;Baoqing Fu1;Baoqing Fu2;Baoqing Fu3;Mengya Zhong4;Yan Yang2;Zeyang Lin5;Xueni Liu6;Junjie Xia2;Jie Wang1;Jie Wang2;Tingting You1;Tingting You2;Changxiu Yan2;Huamei Tang7;Guohong Zhuang2;Zhihai Peng1;Zhihai Peng2;Zhihai Peng81Department of Organ Transplantation, Xiang’an Hospital, Xiamen University, Xiamen, Fujian, China;2Fujian Provincial Key Laboratory of Organ and Tissue Regeneration, Organ Transplantation Institute of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China;3Department of Laboratory Medicine, Xiang’an Hospital, Xiamen University, Xiamen, Fujian, China;4Cancer Research Center, School of Medicine, Xiamen University, Xiamen, Fujian, China;5Department of Pathology, Zhongshan Hospital, Xiamen University, Xiamen, Fujian, China;6Department of General Surgery, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China;7Department of Pathology, Xiang’an Hospital, School of Medicine, Xiamen University, Xiamen, Fujian, China;8Organ Transplantation Clinical Medical Center of Xiamen University, Xiamen, Fujian, China)

出处: Frontiers in Immunology 2023

关键词: inflammatory bowel disease;intestinal microbiota;Musashi2;group 3 innate lymphoid cells;Lactobacillaceae

摘要: BackgroundThe etiology and pathogenesis of inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn’s disease (CD), are generally ...

作者: Shengli Li12;Li Yuan134;Zhi-Yuan Xu134;Jing-Li Xu5;Gui-Ping Chen6;Xiaoqing Guan1;Guang-Zhao Pan1;Can Hu5;Jinyun Dong1;Yi-An Du134;Li-Tao Yang134;Mao-Wei Ni1;Rui-Bin Jiang1;Xiu Zhu1;Hang Lv7;Han-Dong Xu5;Sheng-Jie Zhang1;Jiang-Jiang Qin134CA1;Xiang-Dong Cheng134CA21Department of Gastric Surgery, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institutes of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, 310022, China;2Precision Research Center for Refractory Diseases, Institute for Clinical Research, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China;3Zhejiang Provincial Research Center for Upper Gastrointestinal Tract Cancer, Zhejiang Cancer Hospital, Hangzhou, 310022, China;4Zhejiang Key Lab of Prevention, Diagnosis and Therapy of Upper Gastrointestinal Cancer, Zhejiang Cancer Hospital, Hangzhou, 310022, China;5First Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, 310053, China;6Department of Gastrointestinal Surgery, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310006, China;7Biological Sample Bank, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310006, China)

出处: Nature Communications 2023

摘要: The incidence of adenocarcinoma of the esophagogastric junction (AEG) has been rapidly increasing in recent decades, but its molecular alterations and ...

作者: Renyuan Wang  1, Chang Jiang  2, Zhaoyi Wu  3, Zhe Wang  2, Ying Peng  1, Zhuoxuan Li  1, Zhiyang Zhang  2, Haodong Lin  4, Zixian Chen  5 (Affiliations 1 Trauma center, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, China. 2 Department of Orthopedics, Shanghai Zhongshan Hospital, Fudan University, Shanghai, 200080, China. 3 Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. 4 Trauma center, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, China. Electronic address: haodonglin@hotmail.com. 5 Department of Orthopedics, Shanghai Zhongshan Hospital, Fudan University, Shanghai, 200080, China. Electronic address: chen.zixian@zs-hospital.sh.cn.)

出处: The journal of pain 2023

关键词: Fecal microbiota transplantation;Gut microbiota;Microbiota community;Pain-related behaviors;Postmenopausal allodynia.

摘要: Higher sensitivity to pain is a common clinical symptom in postmenopausal females. The gut microbiota (GM) has recently been identified as participati ...

作者: Qingnan Zhao123;Jiemiao Hu3;Lingyuan Kong3;Shan Jiang4;Xiangjun Tian5;Jing Wang5;Rintaro Hashizume6;Zhiliang Jia3;Natalie Wall Fowlkes7;Jun Yan8;Xueqing Xia3;Sofia F. Yi3;Long Hoang Dao3;David Masopust9;Amy B. Heimberger5;Shulin Li3CA11Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200020, China;2Shanghai Key Laboratory of Pancreatic Disease, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China;3Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA;4Uaub Institute for Research on Alzheimer’s Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, 77030, USA;5Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA;6Department of Neurological Surgery, Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA;7Department of Veterinary Medicine & Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA;8Beijing Institute of Brain Disorders, Capital Medical University, Beijing, 100069, China;9Department of Microbiology, Center for Immunology, University of Minnesota, Minneapolis, MN, 55455, USA)

出处: Nature Communications 2023

摘要: Although tissue-resident memory T (TRM) cells specific for previously encountered pathogens have been characterized, the induction and recr ...

作者: Senlin Lin #  1, Bijun Zhu #  2, Ting Wang  3, Hong Wang  3, Xian Xu  2, Shanshan Wang  2, Yao Yin  4, Zhaoyu Xiang  2, Yu Qian  2, Zhang Zhang  2, Lipu Cui  2, Haidong Zou  5   2, Xiangui He  5, Jianfeng Zhu  5, Yingyan Ma  5   2 (Affiliations 1 Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China. 2 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Fundus Diseases, National Clinical Research Center for Eye Diseases, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China. 3 Department of Preventive Ophthalmology, Yangpu District Kongjiang Hospital, Shanghai, China. 4 Department of Ophthalmology, Fengcheng Hospital, Shanghai, China. 5 Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China mYy_29@163.com jfzhu1974@hotmail.com xianhezi@163.com zouhaidong@sjtu.edu.cn.)

出处: The British journal of ophthalmology 2023

关键词: Epidemiology;Optics and Refraction;Public health.

摘要: Background/aims: We aim to explore the effect of sympathetic nervous system (SNS) on choroid thickness (ChT) and axial length (AL). Methods: Students ...

作者: Zhaohui Ni  1, Renhua Lu  2, Xudong Xu  3, Xueyan Bian  4, Zhihong Zhou  5, Junwei Yang  6, Qun Luo  7, Menghua Chen  8, Chaosheng Chen  9, Xiuli Sun  10, Lei Yu  11, Qiang He  12, Hong Jiang  13, Weijie Yuan  14, Yi Li  15, Rong Zhou  16, Jianqin Wang  17, Xinzhou Zhang  18, Li Zuo  19, Xiangwen Meng  20, Zhiren Chang  21, June Zhao  22, Peter Wessman  23, Peng Xiang  20; DIALIZE China Study Group (Affiliations 1 Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: profnizh@126.com. 2 Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 3 Central Hospital of Minhang District, Shanghai, China. 4 Ningbo First Hospital, Ningbo, China. 5 The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, China. 6 The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China. 7 Ningbo Huamei Hospital, University of Chinese Academy of Sciences, Ningbo, China. 8 General Hospital of Ningxia Medical University, Yinchuan, China. 9 The First Affiliated Hospital of Wenzhou College, Wenzhou, China. 10 Baotou City Central Hospital, Baotou, China. 11 Inner Mongolia People's Hospital, Hohhot, China. 12 Zhejiang Traditional Chinese Medicine Hospital, Hangzhou, China. 13 People's Hospital of Xinjiang Uygur Autonomous Region, Xinjiang, China. 14 Shanghai General Hospital, Shanghai, China. 15 Dongguan People's Hospital, Dongguan, China. 16 Shanghai Yangpu District Central Hospital, Shanghai, China. 17 Lanzhou University Second Hospital, Lanzhou, China. 18 Shenzhen People's Hospital, Shenzhen, China. 19 Peking University People's Hospital, Beijing, China. 20 Global R&D (China), AstraZeneca, Shanghai, China. 21 Global R&D (China), AstraZeneca, Beijing, China. 22 BioPharmaceuticals Clinical, AstraZeneca R&D, Gaithersburg, Maryland. 23 BioPharmaceuticals Clinical, AstraZeneca R&D, Gothenburg, Sweden.)

出处: Clinical therapeutics 2023

关键词: DIALIZE;dialysis;hyperkalemia;sodium zirconium cyclosilicate.

摘要: Purpose: The DIALIZE China study (Reduce Incidence of Pre-Dialysis Hyperkalaemia With Sodium Zirconium Cyclosilicate in Chinese Subjects) (NCT04217590 ...

作者: Desheng Chen  1, Yichao Lou  1, Jing Lu  1, Xuhui Fan  2, Qi Zhu  1, Hongcheng Sun  1 (Affiliations 1 Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. 2 Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.)

出处: International journal of molecular sciences 2023

关键词: TMEM201;hepatocellular carcinoma;immune landscape;prognosis;transmembrane protein.

摘要: Aberrant transmembrane protein (TMEM) expression is implicated in tumor progression, but its functional role in hepatocellular carcinoma (HCC) is uncl ...

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