作者： Renyuan Wang  ^{1   2}, Song Gu  ², Young Hwa Kim  ³, Aejin Lee  ⁴, Haodong Lin  ², Dongsheng Jiang  ^{1   2   5} （Affiliations ¹ Precision Research Center For Refractory Diseases, Shanghai General Hospital Shanghai Jiao Tong University School of Medicine Shanghai China. ² Trauma Center, Shanghai General Hospital Shanghai Jiao Tong University School of Medicine Shanghai China. ³ Inflamm-Aging Translational Research Center Ajou University Medical Center Suwon Republic of Korea. ⁴ Food and Nutrition Major, Division of Integrative Biosciences Myongji University Yongin Republic of Korea. ⁵ Shanghai Jiao Tong University Pioneer Research Institute For Molecular and Cell Therapies, State Key Laboratory of Innovative Immunotherapy, School of Pharmacy, Shanghai Jiao Tong University Shanghai China.）

出处： MedComm 2025

关键词： animal models;cellular dysfunction;diabetic wounds;emerging therapies;metabolic microenvironment.

摘要： Diabetic wound healing, characterized by persistent inflammation, impaired angiogenesis, and dysfunctional cellular responses, remains a major clinica ...

作者： Haihua Huang ¹, Yi Hu ², Peize Meng ³, Xinyue Yang ⁴, Yanxue Ma ⁵, Yongxin Zhou ⁶, Zheng Ruan ⁷ （Affiliations ¹ Thoracic surgery, Shanghai General Hospital, 650, Shanghai, 200080, CHINA. ² Trauma Center, Shanghai General Hospital, Shanghai Jiaotong University, 650, Shanghai, 201620, CHINA. ³ Department of Thoracic Surgery, Shanghai General Hospital, Shanghai Jiaotong University, 650, Shanghai, 201620, CHINA. ⁴ Donghua University College of Textiles, 2999 Renminbei Rd,Songjiang District,Shanghai, Shanghai, Shanghai, 201620, CHINA. ⁵ Donghua University, 2999 Renminbei Rd,Songjiang district,Shanghai, Shanghai, 201620, CHINA. ⁶ Department of Thoracic Surgery, Tongji Hospital Affiliated to Tongji University, 389，Xincun Road,Putuo District,Shanghai 200065,China, Shanghai, Shanghai, 200065, CHINA. ⁷ Shanghai General Hospital, 650, Shanghai, 200080, CHINA.）

出处： Biomedical materials (Bristol, England) 2025

关键词： CSEM stents;PW stents;degradation;radial support force;tracheal fistula.

摘要： The use of covered self-expandable metal (CSEM) stents for fistulas sealing is a common clinical approach. However, these stents need to be removed on ...

作者： Qinghua Niu  ¹, Shiyun Yang  ¹, Lianfang Du  ¹, Chao Jia  ¹, Gang Li  ¹, Yingyu Cai  ¹, An Chen  ², Fan Li  ³ （Affiliations ¹ Department of Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ Department of Ultrasound, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： The British journal of radiology 2025

关键词： Contrast-enhanced ultrasound;Magnetic resonance imaging;Specificity;Ultrasound;Pathological nipple discharge.

摘要： Objective: To evaluate the auxiliary role of contrast-enhanced ultrasound (CEUS) in the etiological diagnosis of pathological nipple discharge (PND) a ...

作者： Deyuan Chen ¹, Zhikai Wen ^{2 3}, Gang Huang ^{3 4}, Qingqing Ruan ³, Chunmei Wen ³, Jinxia Qi ⁵, Qingqing Zhuang ⁶, Ni Xie ⁷, Xuezhi Yang ⁸, Jie Deng ³ （Affiliations ¹ Department of Pathology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China. ² Department of Hepatopancreatobiliary Surgery, The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, China. ³ Zhejiang Key Laboratory of Intelligent Cancer Biomarker Discovery and Translation, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China. ⁴ Department of Thoracic Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China. ⁵ Biobank, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China. ⁶ Department of Neurology, Wenzhou Central Hospital, Wenzhou, China. ⁷ Department of Gastroenterology, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China. ⁸ Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.）

出处： Phytotherapy research : PTR 2025

关键词： Formosanin C;autophagy;endoplasmic reticulum stress;p38;pancreatic ductal adenocarcinoma;reactive oxygen species.

摘要： PDAC, also known as pancreatic ductal adenocarcinoma, is a highly aggressive form of cancer that currently lacks efficient treatment options. Formosan ...

作者： Hong-Zhen Xu ¹, Nan Lin ², Guan-Nan Bai ³, Yu-Lin Liu ⁴, Xiao-Hui Jia ⁵, Cong Huang ⁶, Liang Hu ⁶, Han-Qing Shao ⁷, Qi-Yun Shang ⁸, Li-Fang Zhang ⁹, Ying-Shuo Wang ⁷, Yuan-Yuan Zhang ⁷, Lan-Fang Tang ⁷, Yun-Lian Zhou ⁷, Guo-Hong Zhu ⁷, Jian-Guo Hong ¹⁰, Zhi-Min Chen ¹¹ （Affiliations ¹ Nursing Department, National Clinical Research Center for Child Health, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, 310052, China. 6184020@zju.edu.cn. ² Nursing Department, National Clinical Research Center for Child Health, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, 310052, China. ³ Department of Child Health Care, National Clinical Research Center for Child Health, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, 310052, China. guannanbai@zju.edu.cn. ⁴ Department of Respiratory, Children's Hospital of Chongqing Medical University, Chongqing, 401122, China. ⁵ Department of Pediatric Respiratory Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325035, China. ⁶ Department of Sports Science, College of Education, Zhejiang University, Hangzhou, 310058, China. ⁷ Department of Pulmonology, National Clinical Research Center for Child Health, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, 310052, China. ⁸ Department of Pediatric Respiratory Disease, Anhui Provincial Children's Hospital, Hefei, 230051, China. ⁹ Department of Respiratory and Critical Care Medicine, Kunming Children's Hospital, Kunming, 650000, China. ¹⁰ Department of Pediatrics, Shanghai General Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, 200080, China. hongjianguo@hotmail.com. ¹¹ Department of Pulmonology, National Clinical Research Center for Child Health, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, 310052, China. zmchen@zju.edu.cn.）

出处： World journal of pediatrics : WJP 2025

关键词： Asthma;Child;Exercise;Exercise-induced bronchoconstriction;Recommendation.

摘要： Background: Bronchial asthma is a common chronic respiratory disease in children. For many years, concerns about exercise-induced bronchoconstriction ...

作者： Mengna Lin ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Feixiang Xu ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Yiyu Deng ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Ying Wei ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Feng Shi ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Yun Xie ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Cuiying Xie ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Chen Chen ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Jianfeng Song ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Yao Shen ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Yiyan Lin ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Hailin Ding ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Yannan Zhou ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Su Lu ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Yumei Chen ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Lulu Lan ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Wenxin Zhao ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Jing Zhu ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Zhongshu Kuang ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Wei Pang ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Sijin Que ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Xiaoyu Fang ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Ran Ji ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Chenyang Dong ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Jiancheng Zhang ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Qi Liu ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Zhaocai Zhang ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Chengjin Gao ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Lei Chen ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Yuanlin Song ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Liying Zhan ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Lihong Huang ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Xueling Wu ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Ruilan Wang ^{1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20}, Zhenju Song ^{21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40};Sepsis and ARDS Clinical Research Collaborative Network of China （Affiliations ¹ Department of Emergency Medicine, Zhongshan Hospital, Fudan University, Shanghai, China. ² Department of Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China. ³ Department of Research and Development, United Imaging Intelligence, Shanghai, China. ⁴ Department of Emergency and Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁵ Department of Emergency Medicine, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁶ Department of Emergency Medicine, Minhang Hospital, Fudan University, Shanghai, China. ⁷ Department of Respiratory and Critical Care Medicine, Pudong Hospital, Fudan University, Shanghai, China. ⁸ Emergency Intensive Care Ward, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China. ⁹ Department of Emergency Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ¹⁰ Department of Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan, Hubei, China. ¹¹ Department of Critical Care Medicine, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. ¹² Department of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. ¹³ Department of Respiratory and Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China. ¹⁴ Shanghai Key Laboratory of Lung Inflammation and Injury, Shanghai, China. ¹⁵ Department of Biostatistics, Zhongshan Hospital, Fudan University, Shanghai, China. ¹⁶ Department of Respiratory and Critical Care Medicine, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ¹⁷ Shanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai, China. ¹⁸ Institute of Emergency Rescue and Critical Care, Fudan University, Shanghai, China. ¹⁹ Contributed equally as first authors. ²⁰ Contributed equally as senior authors. ²¹ Department of Emergency Medicine, Zhongshan Hospital, Fudan University, Shanghai, China song.zhenju@zs-hospital.sh.cn wangyusun@hotmail.com wuxueling76@126.com. ²² Department of Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China song.zhenju@zs-hospital.sh.cn wangyusun@hotmail.com wuxueling76@126.com. ²³ Department of Research and Development, United Imaging Intelligence, Shanghai, China song.zhenju@zs-hospital.sh.cn wangyusun@hotmail.com wuxueling76@126.com. ²⁴ Department of Emergency and Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China song.zhenju@zs-hospital.sh.cn wangyusun@hotmail.com wuxueling76@126.com. ²⁵ Department of Emergency Medicine, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China song.zhenju@zs-hospital.sh.cn wangyusun@hotmail.com wuxueling76@126.com. ²⁶ Department of Emergency Medicine, Minhang Hospital, Fudan University, Shanghai, China song.zhenju@zs-hospital.sh.cn wangyusun@hotmail.com wuxueling76@126.com. ²⁷ Department of Respiratory and Critical Care Medicine, Pudong Hospital, Fudan University, Shanghai, China song.zhenju@zs-hospital.sh.cn wangyusun@hotmail.com wuxueling76@126.com. ²⁸ Emergency Intensive Care Ward, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China song.zhenju@zs-hospital.sh.cn wangyusun@hotmail.com wuxueling76@126.com. ²⁹ Department of Emergency Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China song.zhenju@zs-hospital.sh.cn wangyusun@hotmail.com wuxueling76@126.com. ³⁰ Department of Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan, Hubei, China song.zhenju@zs-hospital.sh.cn wangyusun@hotmail.com wuxueling76@126.com. ³¹ Department of Critical Care Medicine, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China song.zhenju@zs-hospital.sh.cn wangyusun@hotmail.com wuxueling76@126.com. ³² Department of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China song.zhenju@zs-hospital.sh.cn wangyusun@hotmail.com wuxueling76@126.com. ³³ Department of Respiratory and Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China song.zhenju@zs-hospital.sh.cn wangyusun@hotmail.com wuxueling76@126.com. ³⁴ Shanghai Key Laboratory of Lung Inflammation and Injury, Shanghai, China song.zhenju@zs-hospital.sh.cn wangyusun@hotmail.com wuxueling76@126.com. ³⁵ Department of Biostatistics, Zhongshan Hospital, Fudan University, Shanghai, China song.zhenju@zs-hospital.sh.cn wangyusun@hotmail.com wuxueling76@126.com. ³⁶ Department of Respiratory and Critical Care Medicine, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China song.zhenju@zs-hospital.sh.cn wangyusun@hotmail.com wuxueling76@126.com. ³⁷ Shanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai, China song.zhenju@zs-hospital.sh.cn wangyusun@hotmail.com wuxueling76@126.com. ³⁸ Institute of Emergency Rescue and Critical Care, Fudan University, Shanghai, China song.zhenju@zs-hospital.sh.cn wangyusun@hotmail.com wuxueling76@126.com. ³⁹ Contributed equally as first authors song.zhenju@zs-hospital.sh.cn wangyusun@hotmail.com wuxueling76@126.com. ⁴⁰ Contributed equally as senior authors song.zhenju@zs-hospital.sh.cn wangyusun@hotmail.com wuxueling76@126.com.）

出处： The European respiratory journal 2025

摘要： Background: Host responses during ARDS are highly heterogeneous, contributing to inconsistent therapeutic outcomes. Proteome-based phenotyping may ide ...

作者： Ji Wang ^{#  1   2   3}, Jian Chang ^{#  2}, Qing Yu  ^{1   3}, Jun Liu  ^{1   3}, Zhihuang Zheng  ¹, Jinfang Bao  ^{1   3} （Affiliations ¹ Department of Nephrology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China. ² Nursing Department, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China. ³ Peritoneal Dialysis Center of Shanghai General Hospital (South), Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.）

出处： International journal of nephrology and renovascular disease 2025

关键词： end-stage renal disease;fluid volume overload;intelligent platform;novel follow-up mode;nurse-led care;peritoneal dialysis.

摘要： Purpose: To evaluate the effect of a novel follow-up mode integrating specialist nurse-led care and an intelligent platform on fluid volume management ...

作者： Huibiao Deng  ¹, Xiaoyuan Gong  ², Meiling Wang  ³, Qingqing Zhang  ⁴, Fei Li  ⁴, Xiaohong Wu  ⁵, Qidi Zhang  ⁴ （Affiliations ¹ Department of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of Endoscopy Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ Department of Gastroenterology, Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai. ⁴ Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁵ Department of Outpatient Department, Shanghai University of International Business and Economics, Shanghai, China.）

出处： Hepatic oncology 2025

关键词： Second primary malignancy;bile duct cancer;gallbladder cancer;hepatocellular carcinoma;shared etiologic factors.

摘要： Aim: Our aim was to examine two-way increased-risk associations between hepatobiliary cancers and malignancies that develop before/after them. Patient ...

作者： Xin-Xin Sun ^{#  1}, Lin Qi ^{#  2}, Ming-Jun Dai ^{#  2}, Fang-Lin Lu  ³, Yi-Min Xiao  ¹, Wei-Jin Sun  ⁴, Yu Zhuang  ⁵ （Affiliations ¹ Department of Cardiovascular Surgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200120, China. ² Nursing Department, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. ³ Department of Cardiovascular Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. ⁴ Nursing Department, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. weijin.sun@shgh.cn. ⁵ Department of Cardiovascular Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. yu.zhuang@shgh.cn.）

出处： Journal of molecular medicine (Berlin, Germany) 2025

关键词： Apoptosis;Autophagic flux;Myocardial ischemia-reperfusion injury;OTUD4;UBAC1.

摘要： Dysregulated autophagic flux plays a critical role in myocardial ischemia-reperfusion injury (MIRI), complicating cardiac reperfusion therapy. In this ...

作者： Yu Su  ^{1   2}, Chenqi Yang  ^{1   3}, Hong Liao  ⁴, Zhenbo Zhang  ⁵, Yuan Xu  ⁶, Yang Zhao  ⁷, Yanhua Wang  ⁸, Dayong Wang  ⁹, Lei Wang  ¹⁰, Rong Ji  ³, Xiaoli Zhao  ¹¹, Baoshan Xing  ² （Affiliations ¹ Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China. ² Stockbridge School of Agriculture, University of Massachusetts, Amherst, Massachusetts 01003, United States. ³ State Key Laboratory of Water Pollution Control and Green Resource Recycling, School of the Environment, Nanjing University, Nanjing 210023, China. ⁴ Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai 200040, China. ⁵ Tongji Hospital, School of Medicine, Tongji University, Shanghai 200092, China. ⁶ Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200080, China. ⁷ School of Energy and Environment, Southeast University, Nanjing 211189, China. ⁸ School of Geography and Tourism, Shaanxi Normal University, Xi'an 710119, China. ⁹ School of Medicine, Southeast University, Nanjing 210009, China. ¹⁰ College of Environmental Science and Engineering, Nankai University, Tianjin 300350, China. ¹¹ State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China.）

出处： Environment & health (Washington, D.C.) 2025

关键词： assisted reproduction technology;microplastics;optical photothermal infrared imaging;protein corona;scratching damage.

摘要： The global prevalence of infertility boosts the demands for assisted reproduction technology (ART) and medical plasticware for processing human reprod ...