作者： Ying Peng  ¹, Zhuoxuan Li  ¹, Zhiyang Zhang  ², Yinglun Chen  ³, Renyuan Wang  ¹, Nixi Xu  ², Yuanwu Cao  ², Chang Jiang  ², Zixian Chen  ², Haodong Lin  ¹ （Affiliations ¹ Trauma Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of Orthopedics, Zhongshan Hospital, Fudan University, Shanghai, China. ³ Department of Rehabilitation Medicine, Shanghai Geriatric Medical Center, Shanghai, China.）

出处： Neural regeneration research 2024

关键词： bromocriptine;central nervous system;cytosolic phospholipase A2;high-content screening;lipid droplet;lipid metabolism;lipotoxicity;mitogen-activated protein kinase;spinal cord injury;spinal cord neurons.

摘要： Recent studies have revealed that lipid droplets accumulate in neurons after brain injury and evoke lipotoxicity, damaging the neurons. However, how l ...

作者： Hengxing Zhou  ¹, Yongfu Lou  ², Lingxiao Chen  ³, Yi Kang  ⁴, Lu Liu  ⁵, Zhiwei Cai  ⁶, David B Anderson  ⁷, Wei Wang  ⁸, Chi Zhang  ⁸, Jinghua Wang  ⁹, Guangzhi Ning  ⁴, Yanzheng Gao  ¹⁰, Baorong He  ⁵, Wenyuan Ding  ¹¹, Yisheng Wang  ¹², Wei Mei  ¹³, Yueming Song  ¹⁴, Yue Zhou  ¹⁵, Maosheng Xia  ¹⁶, Huan Wang  ¹⁷, Jie Zhao  ¹⁸, Guoyong Yin  ¹⁹, Tao Zhang  ²⁰, Feng Jing  ²¹, Rusen Zhu  ²², Bin Meng  ²³, Li Duan  ²⁴, Zhongmin Zhang  ²⁵, Desheng Wu  ²⁶, Zhengdong Cai  ²⁷, Lin Huang  ²⁸, Zhanhai Yin  ²⁹, Kainan Li  ³⁰, Shibao Lu  ³¹, Shiqing Feng  ³² （Affiliations ¹ Department of Orthopedics, The Second Hospital, Cheeloo College of Medicine; Department of Orthopedics, Shandong University Center for Orthopedics, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Shandong, China. ² Department of Orthopedics, The Second Hospital, Cheeloo College of Medicine, Shandong University, Shandong; Department of Orthopedics, Tianjin Medical University General Hospital, International Science and Technology Cooperation Base of Spinal Cord Injury, Tianjin Key Laboratory of Spine and Spinal Cord, Tianjin, China. ³ Department of Orthopedics, Shandong University Center for Orthopedics, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Shandong, China; Faculty of Medicine and Health, The Back Pain Research Team, Sydney Musculoskeletal Health, The Kolling Institute, University of Sydney, Sydney, NSW, Australia. ⁴ Department of Orthopedics, Tianjin Medical University General Hospital, International Science and Technology Cooperation Base of Spinal Cord Injury, Tianjin Key Laboratory of Spine and Spinal Cord, Tianjin, China. ⁵ Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi Province, China. ⁶ Department of Burns and Plastic Surgery, The Fourth Medical Center of Chinese PLA General Hospital, Beijing, China. ⁷ Faculty of Medicine and Health, School of Health Sciences, University of Sydney; Sydney Spine Institute, Burwood, Sydney, NSW, Australia. ⁸ Department of Orthopedics, Shandong University Center for Orthopedics, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Shandong, China. ⁹ Laboratory of Epidemiology, Tianjin Neurological Institute, Department of Neurology, Tianjin Medical University General Hospital & Tianjin Neurological Institute, Key Laboratory of Post-Neuroinjury Neuro-repair and Regeneration in Central Nervous System, Ministry of Education and Tianjin City, Tianjin, China. ¹⁰ Department of Orthopedics, Henan Provincial People's Hospital, Zhengzhou, Henan Province, China. ¹¹ Department of Spinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, China. ¹² Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China. ¹³ Department of Spine Surgery, Zhengzhou Orthopedics Hospital, Zhengzhou, Henan Province, China. ¹⁴ Department of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China. ¹⁵ Department of Orthopedics, Xinqiao Hospital, Army Medical University, Chongqing, China. ¹⁶ Department of Orthopedics, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning Province, China. ¹⁷ Department of Spinal Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China. ¹⁸ Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ¹⁹ Department of Orthopedics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China. ²⁰ Department of Spinal Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China. ²¹ Department of Spinal Surgery, Tianjin Hospital, Tianjin, China. ²² Department of Spine Surgery, Tianjin Union Medical Center, Tianjin, China. ²³ Department of Orthopedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China. ²⁴ Department of Orthopedics, Shenzhen Intelligent Orthopedics and Biomedical Innovation Platform, Guangdong Artificial Intelligence Biomedical Innovation Platform, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, Guangdong Province, China. ²⁵ Department of Orthopedics, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong Province, China. ²⁶ Department of Spine Surgery, Shanghai East Hospital Affiliated to Tongji University School of Medicine, Shanghai, China. ²⁷ Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ²⁸ Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong Province, China. ²⁹ Department of Orthopedics, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi Province, China. ³⁰ Department of Orthopedic Surgery, Affiliated Hospital of Chengdu University, Chengdu, Sichuan Province, China. ³¹ Department of Orthopedics, Beijing Xuanwu Hospital, Capital Medical University, Beijing, China; National Geriatric Diseases Research Center, Beijing, China. ³² Department of Orthopedics, The Second Hospital, Cheeloo College of Medicine; Department of Orthopedics, Shandong University Center for Orthopedics, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Shandong; Department of Orthopedics, Tianjin Medical University General Hospital, International Science and Technology Cooperation Base of Spinal Cord Injury, Tianjin Key Laboratory of Spine and Spinal Cord, Tianjin, China.）

出处： Neural regeneration research 2024

关键词： China;clinical features;costs;epidemiology;methylprednisolone;methylprednisolone sodium succinate;retrospective study;traumatic spinal cord injury;treatment.

摘要： Traumatic spinal cord injury is potentially catastrophic and can lead to permanent disability or even death. China has the largest population of patie ...

作者： Xiao-Ping Wang;Bo Wang （Affiliations ¹ Jiading Branch of Shanghai General Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China. ² Zhongshan Hospital, Fudan University, Shanghai, China.）

出处： Frontiers in pain research (Lausanne, Switzerland) 2023

关键词： VSL#3;abdominal and pelvic pain;acupuncture;endometriosis;irritable bowel syndrome;neuropathy.

摘要： This paper provides a description and evaluation of the main features of John Wilson's approach to moral education. In the first section we analyse th ...

作者： Yuhang Ma;Ying Zhang;Yi Lin;Xiaoying Ding;Yuntao Zhang （Affiliations ¹ Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. ² School of Digital Construction, Shanghai Urban Construction Vocational College, Shanghai, 201999, China.）

出处： Open medicine (Warsaw, Poland) 2023

关键词： biomechanical property;bone mineral density;histomorphometry;osteogenic growth peptide C-terminal pentapeptide;osteoporosis.

摘要： This study aimed to explore the effects of osteogenic growth peptide C-terminal pentapeptide (G36G), and its analog G48A on bone modeling in rats with ...

作者： Jiawei Lu;Pusheng Yang;Lanting Yu;Ni Xie;Ying Wu;Baiwen Li （Affiliations ¹ Department of Gastroenterology, Shanghai Key Laboratory of Pancreatic Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, China. ² Department of Obstetrics and Gynecology, Shanghai Key Laboratory of Gynecology Oncology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.）

出处： Diagnostics (Basel, Switzerland) 2023

关键词： immune infiltration;lncRNA;m7G;overall survival;pancreatic adenocarcinoma;prognostic signature.

摘要： N7-Methylguanosine (m7G) modification holds significant importance in regulating posttranscriptional gene expression in epigenetics. Long non-coding R ...

作者： Shan Huang ^{#  1}, Qimin Zhang ^{#  1}, Manyu Zhao  ¹, Xing Wang  ^{2   3}, Yilei Zhang  ⁴, Boyi Gan  ⁵, Peijing Zhang  ¹ （Affiliations ¹ Department of Oncology, National Engineering Research Center for Nanomedicine, Key Laboratory of Molecular Biophysics of Ministry of Education, College of Life Science and Technology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China. ² Translational Medicine Center, Shanghai General Hospital, Shanghai JiaoTong University School of Medicine , Shanghai, China. ³ Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College , Nanchang, China. ⁴ Department of Biochemistry and Molecular Biology, The Institute of Molecular and Translational Medicine, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, China. ⁵ Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.）

出处： The Journal of cell biology 2023

摘要： The dependency of cancer cells on iron increases their susceptibility to ferroptosis, thus providing new opportunities for patients with treatment-res ...

作者： Jinrong Lin ^{#  1}, Shurong Zhang ^{#  1}, Enhui Xin ^{#  2}, Meng Liang  ³, Liqin Yang  ⁴, Jiwu Chen  ⁵ （Affiliations ¹ Department of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, 200040, People's Republic of China. ² Department of Radiology, Huashan Hospital, Fudan University, 12 Wulumuqi Middle Road, Jing'an District, Shanghai, 200040, People's Republic of China. ³ Botnar Institute of Musculoskeletal Sciences, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, OX3 7LD, UK. ⁴ Department of Radiology, Huashan Hospital, Fudan University, 12 Wulumuqi Middle Road, Jing'an District, Shanghai, 200040, People's Republic of China. mozi001_ren@sina.com. ⁵ Department of Sports Medicine, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, 100 Haining Road, Hongkou District, Shanghai, 200080, People's Republic of China. jeevechen@gmail.com.）

出处： Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA 2023

关键词： 3D MRI;Anterior cruciate ligament;Anterior cruciate ligament reconstruction;Femoral footprint.

摘要： Purpose: This study aimed to evaluate the morphology of the anterior cruciate ligament (ACL) femoral footprint with three-dimensional magnetic resonan ...

作者： Wenxin Zhu  ¹, Ping'an Pan  ¹, Yonghua Huang  ¹, Wei Chen  ², Sha Han  ², Zheng Li  ², Jinsheng Cheng  ³ （Affiliations ¹ Institute of Refrigeration and Cryogenics, Shanghai Jiao Tong University, Shanghai 200240, P. R. China. ² Department of Andrology, Center for Men's Health, Institute of Urology, Urologic Medical Center, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai 200080, P. R. China. ³ Shanghai Tofflon Medical Equipment Co., Ltd, Shanghai 201108, P. R. China.）

出处： Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 2023

关键词： Cell cryopreservation;Laser warming;Solid surface vitrification;Vitrification.

摘要： Ultra-rapid cooling and rewarming rate is a critical technical approach to achieve ice-free cells during the freezing and melting process. A set of ul ...

作者： J X Fan  ¹, M Zhang  ², W Y Zhao  ³, Y Han  ⁴, W T Hu  ³, H X Jia  ², X D Sun  ² （Affiliations ¹ Information Department, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. ² Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai 200080, China. ³ Shanghai Phoebus Medical Technology Co., Ltd, Shanghai 200070, China. ⁴ Health Economics Research Institute, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.）

出处： [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 2023

摘要： Objective: To perform a health economic evaluation of telemedicine diabetic retinopathy (DR) examination with a non-mydriatic fundus camera in China a ...

作者： Lianhui Sun  ¹;Xing Wang  ²;Lixiao Chen  ³;Zheng Gao  ⁴;Songhui Xu  ⁵;Chen Hu  ¹;Guangjian Fan  ¹;Baoxin Wang  ³;Tingting Feng  ⁶;Wang Wang  ⁷;Xinjiang Ying  ³ （Affiliations ¹ Precision Research Center for Refractory Diseases, Institute for Clinical Research, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. ² Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, China. ³ Department of Otolaryngology Head and Neck Surgery, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 201620, China. ⁴ State Key Laboratory of Protein and Plant Gene Research, Peking-Tsinghua Center for Life Sciences, School of Advanced Agriculture Sciences, Peking University, Beijing, 100871, China. ⁵ Department of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China. ⁶ Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁷ School of Cell and Gene Therapy，Shanghai Jiaotong University School of Medicine, Shanghai, 201600, China.）

出处： Cell insight 2023

摘要： Hypopharyngeal squamous cell carcinoma (HSCC) is a highly aggressive malignancy that constitutes approximately 95% of all hypopharyngeal carcinomas, a ...