作者： Zehao Ding ^{1 2 3 4}, Zai Luo ^{3 4}, Liao Zhang ^{3 4}, Shaopeng Zhang ^{3 4}, Renchao Zhang ^{3 4}, Zhengjun Qiu ^{3 4}, Chen Huang ^{1 2 3 4} （Affiliations ¹ Department of Gastrointestinal Surgery The Affiliated Chuzhou Hospital of Anhui Medical University AnHui China. ² Institute of Gastrointestinal Tumor Research The First People's Hospital of Chuzhou AnHui China. ³ Department of Gastrointestinal Surgery Shanghai General Hospital，Shanghai Jiao Tong University School of Medicine Shanghai China. ⁴ Institute of Gastrointestinal Tumor Research Shanghai General Hospital,Shanghai Jiao Tong University School of Medicine Shanghai China.）

出处： MedComm 2026

关键词： biomarkers;circular RNA;immune evasion;metabolic reprogramming;therapeutic targeting;tumorigenesis.

摘要： Circular RNAs (circRNAs) are characterized by their covalently closed structure, remarkable stability, and precise spatiotemporal regulation, evolving ...

作者： Daixi Chen  ^{1   2}, Tianyu Cheng  ^{1   3}, Linlin Du  ¹, Jun Chen  ¹, Xun Xu  ^{1   2}, Xiangui He  ^{1   2}, Jun Qiang  ^{1   3} （Affiliations ¹ Clinical Research Center, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Tongji University, Shanghai, China. ² Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Center of Eye Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China. ³ Optometry Center, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Tongji University, Shanghai, China.）

出处： Strabismus 2026

关键词： Acute acquired comitant esotropia;ophthalmologic surgical procedures;prism tests;strabismus;treatment surgery.

摘要： Purpose: This study evaluated an abbreviated prism adaptation protocol integrated with alternate prism cover testing (APCT) for more precise measureme ...

作者： Shuchang Zhang ^{# 1 2}, Chenhao Yang ^{# 3}, Qingyu An ^{1 2}, Lei Zhong ^{1 2}, Xixuan Zhao ^{1 2}, Xi Qu ^{1 2}, Yiwei Wu ^{1 2}, Haidong Zou ^{4 5} （Affiliations ¹ Department of Ophthalmology, Shanghai General Hospital, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai, China. ² Shanghai Eye Diseases Prevention & Treatment Center, Shanghai Eye Hospital, School of Medicine, Tongji University, Shanghai, China. ³ Department of Ophthalmology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China. ⁴ Department of Ophthalmology, Shanghai General Hospital, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai, China. zouhaidong@sjtu.edu.cn. ⁵ Shanghai Eye Diseases Prevention & Treatment Center, Shanghai Eye Hospital, School of Medicine, Tongji University, Shanghai, China. zouhaidong@sjtu.edu.cn.）

出处： Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2026

关键词： Type 1 diabetes;axial length;bilirubin;children;β-zone peripapillary atrophy (β-PPA).

摘要： Purpose: To investigate the morphological changes and long-term progression of optic disc peripapillary β-zone atrophy (β-PPA) in children with type 1 ...

作者： Lihao Guo  ^{1   2   3}, Youbin Zheng  ⁴, Shuxiang Xu  ¹, Bingbing Feng  ¹, Kan Wang  ⁵, Rou Huang  ², Gandong Zhou  ^{1   2}, Chutong Liu  ^{1   2}, Rawan Omar  ⁶, Danyao Qu  ⁶, Jinbao Li  ⁷, Min Zhang  ⁸, Weiwei Wu  ³, Guangjian Zhang  ⁹, Lina Huang  ^{1   7}, Hossam Haick  ^{4   6}, Miaomiao Yuan  ¹ （Affiliations ¹ Precision Research Center for Refractory Diseases, Shanghai Jiao Tong University Pioneer Research Institute for Molecular and Cell Therapies, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² School of Advanced Materials and Nanotechnology, Xidian University, Xi'an, China. ³ School of Information Mechanics and Sensing Engineering, Xidian University, Xi'an, China. ⁴ Department of Medicine, Laboratory for Life Sciences and Technology (LiST), Faculty of Medicine and Dentistry, Danube Private University, Krems, Austria. ⁵ School of Automation and Intelligent Sensing, Shanghai Jiao Tong University, Shanghai, China. ⁶ Department of Chemical Engineering and Russell Berrie Nanotechnology Institute, Technion-Israel Institute of Technology, Haifa, Israel. ⁷ Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁸ School of Chemistry and Molecular Engineeringin Situ Devices Research Center, East China Normal University, Shanghai, China. ⁹ Department of Thoracic Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, P. R. China.）

出处： Advanced materials (Deerfield Beach, Fla.) 2026

关键词： biopolymer;biosecurity;fibrotic lesion;microneedle;sensor.

摘要： Long-term monitoring of electrolyte dynamics is essential for managing chronic diseases. Conventional diagnostic tests are steadily evolving toward gr ...

作者： Anqi Lin¹;Yuquan Zhang²;Aimin Jiang³;Lingxuan Zhu⁴;Weiming Mou⁴⁵;Quan Cheng⁶⁷;Jian Zhang⁴;Pengpeng Zhang⁸CA1;Bufu Tang⁹CA2;null;Peng Luo¹CA3 （¹Donghai County People’s Hospital (Affiliated Kangda College of Nanjing Medical University), Department of Oncology, Zhujiang Hospital, Southern Medical University, Lianyungang, China;²School of Clinical Medicine, Hangzhou Medical College, Hangzhou, Zhejiang, China;³Department of Urology, Changhai hospital, Naval Medical University (Second Military Medical University), Shanghai, China;⁴Department of Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou, China;⁵Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;⁶Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, China;⁷National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China;⁸Department of Lung Cancer, Tianjin Lung Cancer Center, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin’s Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China;⁹Department of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, China）

出处： Communications Medicine 2026

摘要： Digital health tools are becoming essential for evaluating and supporting the mental well-being of individuals with cancer. Here, we analyze advanced ...

作者： Jiaxuan Liu ^{# 1 2 3}, Meng Zhang ^{# 4}, Jialing Li ^{# 5}, Yu Tian ⁶, Jinyan Zhao ⁷, Xue Liu ⁸ （Affiliations ¹ Provincial Key Laboratory of Digital Medicine and Biomechanics & Guangdong Engineering Research Center for Translation of Medical 3D Printing Application, Guangzhou, China. ² National Virtual & Reality Experimental Education Center for Medical Morphology, Southern Medical University, Guangzhou, China. ³ Key Discipline of Human Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China. ⁴ Department of Hepatobiliary Surgery, Affiliated Hospital of Hebei University, Baoding, China. ⁵ Department of Family and Community Medicine, University of Illinois College of Medicine Rockford, Rockford, IL, USA. ⁶ Science Research Center, the Huizhou Central People's Hospital, Guangdong Medical University, 41 E Ling North Road, Huizhou, Guangdong, China. Tian_Yu@ben.edu. ⁷ Department of Laboratory Medicine, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, No. 85/86 Wujin Road, Shanghai, China. jingy1213@163.com. ⁸ Department of Interventional Radiology, Eastern Hepatobiliary Surgery Hospital, Third Affiliated Hospital of Naval Medical University, No. 700 Moyu North Road, Shanghai, China. 19830701liu@sina.com.）

出处： Cellular and molecular life sciences : CMLS 2026

关键词： Biomarker;FOXK;Hepatocellular carcinoma;KIF20A;Kinesin family members;Wnt/β-catenin signaling pathway.

摘要： Liver cancer ranks sixth in incidence and third in mortality worldwide, with hepatocellular carcinoma (HCC) accounting for 90% of cases. Kinesin famil ...

作者： Yifei Xu ¹, Xuehua Min ¹, Zihan Zhang ¹, Yulin Zhang ¹, Xiaoting Chen ¹, Xinyu Wang ¹, Caixia Zhu ¹, Erle Robertson ², Qunling Zhang ³, Yin Tong ⁴, Liming Zhang ⁵, Yuyan Wang ⁶, Qiliang Cai ⁷ （Affiliations ¹ MOE/NHC/CAMS Key Laboratory of Medical Molecular Virology, Shanghai Institute of Infections Disease and Biosecurity, Shanghai Frontiers Science Center of Pathogenic Microorganism and Infection, School of Basic Medical Science, Qidong-Fudan Innovative Institute of Medical Science, Shanghai Medical College, Fudan University, Shanghai 200032, P. R. China. ² Department of Otorhinolaryngology-Head and Neck Surgery, and Abramson Comprehensive Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia 19104, USA. ³ Department of Oncology, Shanghai Cancer Hospital, Shanghai 200032, P. R. China. Electronic address: zhangqunling@fudan.edu.cn. ⁴ Department of Hematology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 100 Haining Road, Shanghai 200080, P.R. China. Electronic address: tongyin_cn2@hotmail.com. ⁵ Department of Public Health, Jiangxi Cancer Hospital, Nanchang 330029, P. R. China. Electronic address: zhangliming@ncmc.edu.cn. ⁶ MOE/NHC/CAMS Key Laboratory of Medical Molecular Virology, Shanghai Institute of Infections Disease and Biosecurity, Shanghai Frontiers Science Center of Pathogenic Microorganism and Infection, School of Basic Medical Science, Qidong-Fudan Innovative Institute of Medical Science, Shanghai Medical College, Fudan University, Shanghai 200032, P. R. China. Electronic address: yuyanss@fudan.edu.cn. ⁷ MOE/NHC/CAMS Key Laboratory of Medical Molecular Virology, Shanghai Institute of Infections Disease and Biosecurity, Shanghai Frontiers Science Center of Pathogenic Microorganism and Infection, School of Basic Medical Science, Qidong-Fudan Innovative Institute of Medical Science, Shanghai Medical College, Fudan University, Shanghai 200032, P. R. China; Expert Workstation, Baoji Central Hospital, Baoji 721008, P. R. China. Electronic address: qiliang@fudan.edu.cn.）

出处： Molecular therapy : the journal of the American Society of Gene Therapy 2026

摘要： Cancer metabolic reprogramming generates a hostile tumor microenvironment (TME) characterized by lactate-driven acidosis, fostering tumor progression. ...

作者： Juan Shi ^{# 1 2}, Cong Liu ^{# 1 2}, Jiahang Hu ^{# 1 2}, Yuancheng Dai ^{# 3}, Ying Peng ^{# 1 2}, Fengmei Xu ^{# 4}, Haonan Shi ⁵, Yunsong Li ⁶, Jun Li ⁷, Zunhai Zhou ⁸, Chunfang Wen ⁹, Shan Huang ¹⁰, Yi Shu ¹¹, Xiaolin Ye ¹², Aifang Wang ¹³, Hongxia Zhao ¹⁴, Ping Feng ¹⁵, Shengli Wu ¹⁶, Dandan Wang ¹⁷, Ping Liu ¹⁸, Yi Shi ⁵, Shuhui Yang ¹⁹, Weiwei Tu ²⁰, Lei Chen ²¹, Chaoli Yu ²², Guang Ning ^{1 2}, Yufan Wang ²³, Zhiyun Zhao ^{24 25}, Yifei Zhang ^{26 27}, Weiqing Wang ^{28 29} （Affiliations ¹ Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ Department of Internal Medicine of Traditional Chinese Medicine, Sheyang Diabetes Hospital, Yancheng, China. ⁴ Department of Endocrinology and Metabolism, Hebi Coal (Group) Ltd. General Hospital, Hebi, China. ⁵ School of Artificial Intelligence, State Key Laboratory for Novel Software Technology, Nanjing University, Nanjing, China. ⁶ Department of Endocrine and Metabolic Diseases, Tengchong People's Hospital, Baoshan, China. ⁷ Department of Endocrinology and Metabolism, People's Hospital of Suiping, Zhumadian, China. ⁸ Department of Endocrinology, Yangpu Hospital, Tongji University School of Medicine, Shanghai, China. ⁹ Department of Endocrinology, The People's Hospital of Mengzi, Mengzi, China. ¹⁰ Department of Endocrinology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ¹¹ Department of Endocrinology, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan, China. ¹² Department of Endocrinology, Hangzhou First People's Hospital Tonglu Campus, Hangzhou, China. ¹³ Department of Endocrinology, The People's Hospital of Yuhuan, Taizhou, China. ¹⁴ Department of Endocrinology and Metabolism, Linyi People's Hospital, Dezhou, China. ¹⁵ Department of Endocrinology, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, China. ¹⁶ Endocrine and Metabolism Center, Karamay Municipal Integrated Traditional Chinese Medicine and Western Medicine Hospital (People's Hospital), Karamay, China. ¹⁷ Department of Metabolic Disease Management Center, Zhecheng County People's Hospital, Shangqiu, China. ¹⁸ Department of Endocrinology, Xi'an NO.3 Hospital, the Affiliated Hospital of Northwest University, Xi'an, China. ¹⁹ Department of Endocrinology, Shantou Central Hospital, Shantou, China. ²⁰ Artificial Productivity, Beijing, China. ²¹ Department of Endocrinology, Suzhou Municipal Hospital Affiliated to Nanjing Medical University, Suzhou, China. ²² Department of Endocrinology, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, China. ²³ Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. yyffwang@sina.com. ²⁴ Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. zzybrad@hotmail.com. ²⁵ Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. zzybrad@hotmail.com. ²⁶ Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. feifei-a@163.com. ²⁷ Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. feifei-a@163.com. ²⁸ Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. wqingw@shsmu.edu.cn. ²⁹ Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. wqingw@shsmu.edu.cn.）

出处： Communications medicine 2026

摘要： Background: Cardiorenal-protective sodium-glucose cotransporter-2 inhibitors (SGLT-2i) and glucagon-like peptide-1 receptor agonists (GLP-1RA) lack se ...

作者： Yi-Fan Li ¹, Chen-Qiong Wu ², Yang Long ³, Qi-Feng Yu ², Wei Xu ⁴, Jian-Jie Zhao ⁵, Xiang-Yang Zhang ¹, Zhi-Kun Li ⁶ （Affiliations ¹ Department of Orthopedics, Tong Ren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200336, China. ² Department of Spine, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University, Shanghai 200080, China. ³ Wuxi School of Medicine, Jiangnan University, Wuxi 214122, Jiangsu Province, China. ⁴ Department of Spine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. ⁵ Department of Sport Medicine, Ganzhou Hospital-Nanfang Hospital, Southern Medical University, Ganzhou 341000, Jiangxi Province, China. ⁶ Department of Spine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. lizhikun@shsmu.edu.cn.）

出处： World journal of orthopedics 2026

关键词： COVID-19;Cough;Normalized prevention and control;Osteoporotic vertebral compression fracture;Risk factor.

摘要： Background: Some scholars believe that there is a certain correlation between coronavirus disease 2019 (COVID-19) infection and the occurrence of oste ...

作者： Xiaoqian Zhang ¹, Yanling Song ¹, Xiaofei Huang ¹, Xuan Wang ¹, Weijie Yuan ², Nan Zhu ¹ （Affiliations ¹ Department of Nephrology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of Nephrology, Jintan Affiliated Hospital of Jiangsu University, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Changzhou, China.）

出处： FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026

关键词： DN;DNA methylation;DNMT1;NF2;YAP.

摘要： Aberrant DNA methylation patterns have been linked to diverse pathological conditions, including chronic kidney diseases. However, it remains unclear ...