作者： Jingliang He^1,2,3;Fang Zheng^1,2,3;Li Zhang^1,2,3;Jiangxiong Cai⁴;Yoko Ogawa⁵;Kazuo Tsubota^5,6;Shan Liu^7,8;Xiuming Jin^1,2,3CA1 （¹Eye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, China;²Zhejiang Provincial Key Laboratory of Ophthalmology, Zhejiang Provincial Clinical Research Center for Eye Diseases, China;³Zhejiang Provincial Engineering Institute on Eye Diseases, Hangzhou, Zhejiang, China;⁴School of Medicine, Zhejiang University, China;⁵Department of Ophthalmology, Keio University, School of Medicine, Tokyo, Japan;⁶Tsubota Laboratory, Inc., Tokyo, Japan;⁷Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China;⁸Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai, China）

出处： The Ocular Surface 2024

摘要： Purpose To investigate the global transcriptional landscape of lacrimal gland cell populations in the GVHD mouse model. Methods Single-cell RNA sequen ...

作者： Lingxuan Zhu ^{#  1}, Yancheng Lai ^{#  1}, Weiming Mou ^{#  2}, Haoran Zhang  ¹, Anqi Lin  ¹, Chang Qi  ³, Tao Yang  ⁴, Liling Xu  ¹, Jian Zhang  ⁵, Peng Luo  ⁶ （Affiliations ¹ Department of Oncology, Zhujiang Hospital, Southern Medical University, 253 Industrial Avenue, 510282, Guangzhou, Guangdong, China. ² Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ Institute of Logic and Computation, TU Wien, Wien, Austria. ⁴ Department of Medical Oncology, National Clinical Research Center for Cancer /Cancer Hospital, National Cancer Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. ⁵ Department of Oncology, Zhujiang Hospital, Southern Medical University, 253 Industrial Avenue, 510282, Guangzhou, Guangdong, China. zhangjian@i.smu.edu.cn. ⁶ Department of Oncology, Zhujiang Hospital, Southern Medical University, 253 Industrial Avenue, 510282, Guangzhou, Guangdong, China. luopeng@smu.edu.cn.）

出处： Journal of hematology & oncology 2024

关键词： Academic integrity;Artificial intelligence;ChatGPT;DALL-E;Experimental images;Large language model;Western Blot.

摘要： The rapid advancements in large language models (LLMs) such as ChatGPT have raised concerns about their potential impact on academic integrity. While ...

作者： Yifan Zhu  ^{1   2   3}, Chenyu Jiang  ^{1   2   3}, Jian He  ⁴, Chen He  ⁵, Xingliang Zhou  ^{1   2   3}, Xu Huang  ^{1   2   3}, Yi Shen  ^{1   2   3}, Liwei Wu  ^{1   2   3}, Yongnan Li  ⁶, Bei Feng  ^{1   3}, Yi Yan  ^{1   3}, Jun Li  ⁷, Hao Zhang  ^{1   2   3}, Yiwei Liu  ^{1   2   3} （Affiliations ¹ Heart Center and Shanghai Institute of Pediatric Congenital Heart Disease, Shanghai Children's Medical Center, National Children's Medical Center. ² Department of Cardiothoracic Surgery, Shanghai Children's Medical Center, National Children's Medical Center, and. ³ Shanghai Clinical Research Center for Rare Pediatric Diseases, Shanghai Children's Medical Center, National Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, China. ⁴ State Key Laboratory of Oncogenes and Related Genes, Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁵ Department of Cardiology, The Guangxi Zhuang Autonomous Region Workers' Hospital, Nanning, China. ⁶ Department of Cardiovascular Surgery, The Second Affiliated Hospital of Lanzhou University, Lanzhou, China. ⁷ Department of Cardiology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.）

出处： The Journal of clinical investigation 2024

关键词： Cardiovascular disease;Transplantation.

摘要： Hypothermia is commonly used to protect donor hearts during transplantation. However, patients transplanted with aged donor hearts still have severe m ...

作者： Ruiqi Han ^{#  1}, Huimin Zhong ^{#  2}, Yang Zhang ^{#  1}, Huan Yu  ¹, Yumeng Zhang  ¹, Shouyue Huang  ¹, Zijian Yang  ³, Yisheng Zhong  ^{4   5} （Affiliations ¹ Department of Ophthalmology, Ruijin Hospital Affiliated Medical School, Shanghai Jiaotong University, 197 Ruijin Er Road, Shanghai, 200025, China. ² Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. ³ Department of Ophthalmology, Ruijin Hospital Affiliated Medical School, Shanghai Jiaotong University, 197 Ruijin Er Road, Shanghai, 200025, China. dyangzj@163.com. ⁴ Department of Ophthalmology, Ruijin Hospital Affiliated Medical School, Shanghai Jiaotong University, 197 Ruijin Er Road, Shanghai, 200025, China. yszhong68@126.com. ⁵ Department of Ophthalmology, Wuxi Branch of Ruijin Hospital Affiliated Medical School, Shanghai Jiaotong University, 197 Zhixian Road, Wuxi, China. yszhong68@126.com.）

出处： Journal of translational medicine 2024

关键词： miR-146a;Fibrosis;Glaucoma;Glaucoma filtration surgery;Rat Tenon’s fibroblasts;TGF.

摘要： Purpose: To explore the impact of microRNA 146a (miR-146a) and the underlying mechanisms in profibrotic changes following glaucoma filtering surgery ( ...

作者： Yongai Li ^{#  1}, Runzhi Huang ^{#  2}, Jianxin Ye  ¹, Xiaying Han  ³, Tong Meng  ⁴, Dianwen Song  ⁵, Huabin Yin  ⁶ （Affiliations ¹ Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China. ³ Department of General Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. ⁴ Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. mengtong@medmail.com.cn. ⁵ Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. songdianwen@msn.com. ⁶ Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. yinhuabin@aliyun.com.）

出处： BMC musculoskeletal disorders 2024

关键词： Bioinformatics analysis;CTNNB1;IVDD;eRNA.

摘要： Background: Intervertebral disc degeneration (IVDD) is a common degenerative condition leading to abnormal stress distribution under load, causing int ...

作者： Jun Zhang  ¹, Zai Luo  ¹, Renchao Zhang  ¹, Zehao Ding  ^{1   2}, Yuan Fang  ¹, Chao Han  ¹, Weidong Wu  ¹, Gang Cen  ², Zhengjun Qiu  ¹, Huang Chen  ^{1   2} （Affiliations ¹ Department of Gastrointestinal Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. ² The Affiliated Chuzhou Hospital of Anhui Medical University, Anhui, 239000, China.）

出处： International journal of surgery (London, England) 2024

摘要： Background: Proficient surgical skills are essential for surgeons, making surgical training an important part of surgical education. The development o ...

作者： Zhichao Zhang  ¹, Fuming Wang  ², Jinsong Zhang  ² （Affiliations ¹ Department of Orthopedics, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200240, People's Republic of China. ² State Key Laboratory of Tea Plant Biology and Utilization, School of Tea & Food Science, Anhui Agricultural University, Hefei, Anhui 230036, People's Republic of China.）

出处： ACS nano 2024

作者： Xinran Qin ^{#  1}, Ying Xiao ^{#  2}, Lipu Cui ^{#  1}, Shuli Chen  ¹, Qingyu An  ¹, Tianyi Yuan  ¹, Yiwei Wu  ¹, Qiurong Lin  ³, Chenhao Yang  ⁴, Haidong Zou  ^{5   6   7   8   9} （Affiliations ¹ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of Ophthalmology, Children's Hospital of Fudan University, No. 399 Wanyuan Road, Shanghai, 201102, China. ³ Shanghai Eye Diseases Prevention & Treatment Center, Shanghai Eye Hospital, No.100 Haining Road, Shanghai, 200080, China. ⁴ Department of Ophthalmology, Children's Hospital of Fudan University, No. 399 Wanyuan Road, Shanghai, 201102, China. ychben@hotmail.com. ⁵ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. zouhaidong@sjtu.edu.cn. ⁶ Shanghai Eye Diseases Prevention & Treatment Center, Shanghai Eye Hospital, No.100 Haining Road, Shanghai, 200080, China. zouhaidong@sjtu.edu.cn. ⁷ Shanghai Key Laboratory of Fundus Diseases, Shanghai, China. zouhaidong@sjtu.edu.cn. ⁸ National Clinical Research Center for Eye Diseases, Shanghai, China. zouhaidong@sjtu.edu.cn. ⁹ Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China. zouhaidong@sjtu.edu.cn.）

出处： Acta diabetologica 2024

关键词： Diabetic retinopathy;Optical coherence tomography angiography;Type 1 diabetes.

摘要： Purpose: To evaluate longitudinal changes in optical coherence tomography angiography (OCTA) metrics in children and adolescents with type 1 diabetes ...

作者： Anqi Lin  ¹, Lingxuan Zhu  ^{1   2}, Weiming Mou  ^{1   3}, Zizhi Yuan  ¹, Quan Cheng  ^{4   5}, Aimin Jiang  ⁶, Peng Luo  ¹ （Affiliations ¹ Department of Oncology, Zhujiang Hospital, Southern Medical University, 253 Industrial Avenue, Guangzhou, Guangdong, China. ² Department of Etiology and Carcinogenesis, National Cancer Center/ National Clinical Research Center for Cancer/Cancer Hospital, Changping laboratory, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. ³ Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁴ Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, China. ⁵ National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China. ⁶ Department of Urology, Changhai hospital, Naval Medical University (Second Military Medical University), Shanghai, China.）

出处： International journal of surgery (London, England) 2024

作者： Jiani Lu  ¹, Zhengshan Tang  ^{2   3}, Miaomiao Xu  ^{4   5   6}, Jianqiang Lu  ⁴, Fengmei Wang  ⁷, Xin Ni  ^{2   3}, Changnan Wang  ⁸, Bo Yu  ¹ （Affiliations ¹ Department of Rehabilitation, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China. ² National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, People's Republic of China. ³ National International Joint Research Center for Medical Metabolomics, Xiangya Hospital, Central South University, Changsha, People's Republic of China. ⁴ School of Exercise and Health, Shanghai University of Sport, Shanghai, People's Republic of China. ⁵ School of Physical Education and Health, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China. ⁶ South China Research Center for Acupuncture and Moxibustion, Medical College of Acu-Moxi and Re-Habilitation, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China. ⁷ Department of Obstetrics and Gynecology, 900th Hospital of Joint Logistics Support Force, Fujian Medical University, Fuzhou, People's Republic of China. ⁸ School of Life Sciences, Shanghai University, Shanghai, People's Republic of China.）

出处： Redox report : communications in free radical research 2024

关键词： Cystathionine γ-lyase;ferroptosis;high-fat diet;insulin resistance;oxidative stress;skeletal muscle.

摘要： Objectives: The objective of this study was to investigate whether skeletal muscle cystathionine γ-lyase (CTH) contributes to high-fat diet (HFD)-indu ...