作者： Ziting Lan ^{#  1}, Xiaoying Ding ^{#  2}, Wenli Yang  ¹, Jiajun Yuan  ¹, Yarong Yu  ¹, Lihua Yu  ¹, Xu Dai  ¹, Yufan Wang  ³, Jiayin Zhang  ^{4   5} （Affiliations ¹ Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. yyffwang@sina.com. ⁴ Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. andrewssmu@msn.com. ⁵ Faculty of Medical Imaging Technology, College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine, Shanghai, China. andrewssmu@msn.com.）

出处： European radiology 2025

关键词： Atherosclerosis;Computed tomography angiography;Coronary;Diabetes mellitus;Lipoprotein (a).

摘要： Objectives: To explore the association between baseline Lp (a) levels and high-risk plaques, plaque volume, and plaque progression in patients with di ...

作者： Ningyao Cao ^{#  1   2}, Lili Feng ^{#  1   2}, Wei Xu ^{#  3}, Fanglin He ^{#  1   2}, Caiwen Xiao  ^{1   2}, Yan Liu  ^{1   2}, Weirong Xu  ⁴, Jingjing Cui  ⁴, Yuqian Guo  ⁵, Lianqing Yao  ⁶, Wenwen Xia  ⁷, Fei Chen ^{#  8}, Yong Li ^{#  9}, Chuandi Zhou ^{#  10   11   12}, Xiaofang Xu ^{#  13   14} （Affiliations ¹ Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, No. 639 Zhizaoju Road, Shanghai, 200011, China. ² Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, China. ³ Department of Cooperation and Exchange, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁴ Department of Anesthesiology and Operating Room, The Ninth People's Hospital of Shanghai, Jiao Tong University School of Medicine, No. 639 Zhizaoju Road, Shanghai, 200011, China. ⁵ Department of General Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁶ Department of Ophthalmology & Otolaryngology, Qiaojia County Traditional Chinese Medicine Hospital, Zhaotong, Yunnan, China. ⁷ Department of Pathology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁸ Department of Anesthesiology and Operating Room, The Ninth People's Hospital of Shanghai, Jiao Tong University School of Medicine, No. 639 Zhizaoju Road, Shanghai, 200011, China. CHENF2106@sh9hospital.org.cn. ⁹ Department of Ophthalmology, The Calmette Affiliated Hospital of Kunming Medical University, No. 1228 Beijing Road, Panlong District, Kunming, 650021, Yunnan, China. liyong@kmmu.edu.cn. ¹⁰ Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, No. 639 Zhizaoju Road, Shanghai, 200011, China. chuandi.zhou@shgh.cn. ¹¹ Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, China. chuandi.zhou@shgh.cn. ¹² Innovative Research Team of High-Level Local Universities in Shanghai, Shanghai, China. chuandi.zhou@shgh.cn. ¹³ Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, No. 639 Zhizaoju Road, Shanghai, 200011, China. xuxu0139@hotmail.com. ¹⁴ Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, China. xuxu0139@hotmail.com.）

出处： International journal of retina and vitreous 2025

关键词： Cross-sectional study;Diabetes;Diabetic retinopathy;Tear glucose.

摘要： Purpose: To examine the association between tear glucose (TG) and the presence and severity of diabetic retinopathy (DR) in patients with type 2 diabe ...

作者： Siyu Han ^{#  1}, Shiyu Zhao ^{#  1}, Ran Zhong ^{#  1}, Heyang Liu  ¹, Li Liu  ², Yongji Yan  ³ （Affiliations ¹ Department of Urology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100000, China. ² Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200000, China. ³ Department of Urology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100000, China. yyjdzm@163.com.）

出处： Urolithiasis 2025

关键词： Burden of disease;Disability-adjusted life-years;Incidence;Mortality;Urolithiasis.

摘要： This report analyzes the patterns of urolithiasis in China, India, the United States, and globally from 1990 to 2021 using data from the Global Burden ...

作者： Lin Peng  ¹, Yuhe Liu  ², Wenqian Wu  ², Yong Zhou  ³, Xin Huang  ⁴ （Affiliations ¹ Department of Dermatology, Hair Medical Center of Shanghai Tongji Hospital, Tongji Hospital, School of Medicine, Tongji University, Shanghai, 200065, China. ² Clinical Research Institute, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No.85 Wujin Road, Shanghai, 200080, China. ³ Clinical Research Institute, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No.85 Wujin Road, Shanghai, 200080, China. yongzhou78214@163.com. ⁴ Department of Dermatology, Hair Medical Center of Shanghai Tongji Hospital, Tongji Hospital, School of Medicine, Tongji University, Shanghai, 200065, China. alida_huang@163.com.）

出处： BMC public health 2025

关键词： Community-based study;Diet;Female androgenetic alopecia;Lifestyle;Prevalence.

摘要： Background: To explore unhealthy diet and lifestyle factors associated with female androgenetic alopecia (FAGA) in a community-based study. Methods: A ...

作者： Di Pan  ^{1   2}, Xiaoling Dai  ³, Pan Li  ⁴, Luan Xue  ¹ （Affiliations ¹ Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of China. ² Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China. ³ Shanghai Putuo Traditional Chinese Medicine Hospital, Shanghai, People's Republic of China. ⁴ Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of China.）

出处： International journal of chronic obstructive pulmonary disease 2025

关键词： Mendelian randomization;ankylosing spondylitis;causal relationship;chronic obstructive pulmonary disease.

摘要： Background: Previous studies have found an association between ankylosing spondylitis (AS) and chronic obstructive pulmonary disease (COPD); however, ...

作者： Kuokuo Li  ^{1   2   3}, Yuge Chen  ^{1   2   3}, Yuying Sheng  ^{1   2   3}, Dongdong Tang  ^{1   2   3}, Yunxia Cao  ^{1   2   3}, Xiaojin He  ⁴ （Affiliations ¹ Department of Obstetrics and Gynecology, Reproductive Medicine Center, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China. ² NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei, Anhui, China. ³ Engineering Research Center of Biopreservation and Artificial Organs, Ministry of Education, Hefei, Anhui, China. ⁴ Department of Obstetrics and Gynecology, Reproductive Medicine Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Human reproduction update 2025

关键词： cis-acting element;infertility;mRNA splicing;non-canonical splicing variant;splicing variant prediction and validation;therapy;trans-acting factor.

摘要： Background: mRNA splicing is a fundamental process in the reproductive system, playing a pivotal role in reproductive development and endocrine functi ...

作者： Pengtao Shi  ¹, Shen Rui  ², Qingyou Meng  ^{3   4} （Affiliations ¹ Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, 214122, China. ² School of Pharmacy, China Medical University, Shenyang, 110122, China. 2024110394@cmu.edu.cn. ³ Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, 214122, China. mengqy@163.com. ⁴ Department of Cardiovascular Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. mengqy@163.com.）

出处： BMC cardiovascular disorders 2025

关键词： 28-Day Mortality;Cardiac Surgery;Creatinine to Albumin Ratio;MIMIC-IV Database.

摘要： Background: Creatinine-to-albumin ratio (CAR) has been recognized as a predictive indicator in the postoperative setting. However, its relationship wi ...

作者： Yue Wu ^{#  1}, Siyuan Wu ^{#  1}, Yinghai Yu ^{#  2   3}, Xiaojun Hu  ², Ting Zhao  ¹, Yan Jiang  ¹, Bilian Ke  ¹ （Affiliations ¹ Department of Ophthalmology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai, China. ³ School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.）

出处： Frontiers in cell and developmental biology 2025

关键词： blinking pattern;children;deep learning system;orthokeratology;tear film.

摘要： Purpose: Using deep learning model to observe the blinking characteristics and evaluate the changes and their correlation with tear film characteristi ...

作者： Nana Wang  ^{1   2}, Yan Hou  ³, Lili Lin  ², Shihui Xu  ³, Kyubae Lee  ⁴, Yingjun Yang  ⁵, Yazhou Chen  ⁶, Yachun Li  ², Xiuhui Wang  ⁷, Yongtao Wang  ², Tao Chen  ¹ （Affiliations ¹ Department of Orthopedic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. ² Department of Pediatrics, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 200080, China. ³ School of Medicine, Shanghai University, Shanghai, 200444, China. ⁴ Department of Biomedical Materials, Konyang University, Daejeon, 35365, Republic of Korea. ⁵ Materials Institute of Atomic and Molecular Science, Shaanxi University of Science and Technology, Xi'an, 710021, China. ⁶ Henan Institute of Advanced Technology, Zhengzhou University, Zhengzhou, 450003, China. ⁷ Institute of Translational Medicine, Shanghai University, Shanghai, 200444, China.）

出处： Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025

关键词： advanced microarrays;force‐sensing mechanotransduction;heterogeneous focal adhesion;mechanical remodeling;nuclear configuration.

摘要： Integrin and focal adhesion can regulate cytoskeleton distribution to govern actin-related force remodeling and play an important role in nuclear conf ...

作者： Hongyuan Song ^{#  1   2   3   4}, Qing Li ^{#  5   6}, Xiao Gui ^{#  5   7}, Ziyu Fang ^{#  8}, Wen Zhou ^{#  5}, Mengzhu Wang  ⁵, Yuxin Jiang  ^{9   10}, Ajun Geng  ^{11   12}, Xi Shen  ¹³, Yongxuan Liu  ⁵, Haorui Zhang  ⁵, Zheng Nie  ⁵, Lin Zhang  ⁵, Huimin Zhu  ⁵, Feng Zhang  ¹⁴, Xuri Li  ¹⁴, Fanyan Luo  ¹⁵, Hongjian Zhang  ^{16   17}, Wei Shen  ¹⁸, Xiaodong Sun  ^{19   20   21} （Affiliations ¹ Department of Ophthalmology, Shanghai Changhai Hospital, Shanghai, China. hongyuansong@hotmail.com. ² Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. hongyuansong@hotmail.com. ³ National Clinical Research Center for Ophthalmic Diseases, Shanghai, China. hongyuansong@hotmail.com. ⁴ Oriental Pan-Vascular Devices Innovation College, University of Shanghai for Science and Technology, Shanghai, China. hongyuansong@hotmail.com. ⁵ Department of Ophthalmology, Shanghai Changhai Hospital, Shanghai, China. ⁶ The Affiliated Eye Hospital of Nanjing Medical University, Nanjing, China. ⁷ Department of Ophthalmology, Yuanwang Hospital, Wuxi, China. ⁸ Department of Urology, Shanghai Changhai Hospital, Shanghai, China. ⁹ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ¹⁰ Shanghai Key Laboratory of Fundus Diseases, Shanghai, China. ¹¹ Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, Hangzhou, China. ¹² New Cornerstone Science Laboratory, State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China. ¹³ Department of Ophthalmology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ¹⁴ State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China. ¹⁵ Department of Cardiac Surgery, Xiangya Hospital, Central South University, Changsha, China. drlfy@csu.edu.cn. ¹⁶ Oriental Pan-Vascular Devices Innovation College, University of Shanghai for Science and Technology, Shanghai, China. hongjian_zhang@usst.edu.cn. ¹⁷ Shidong Hospital Affiliated to University of Shanghai for Science and Technology, 999 Shiguang Road, Shanghai, China. hongjian_zhang@usst.edu.cn. ¹⁸ Department of Ophthalmology, Shanghai Changhai Hospital, Shanghai, China. shenwei@smmu.edu.cn. ¹⁹ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. xdsun@sjtu.edu.cn. ²⁰ National Clinical Research Center for Ophthalmic Diseases, Shanghai, China. xdsun@sjtu.edu.cn. ²¹ Shanghai Key Laboratory of Fundus Diseases, Shanghai, China. xdsun@sjtu.edu.cn.）

出处： Nature communications 2025

摘要： Pathological retinal neovascularization (RNV) is one of the leading causes of blindness worldwide; however, its underlying mechanism remains unclear. ...