作者： Jinghan Song  ¹, Xiong Ye  ², Hui Xiao  ¹ （Affiliations ¹ Department of Respiratory and Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: xiaohui771210@163.com. ² School of Clinical Medicine, Shanghai University of Medicine & Health Sciences, Shanghai, China.）

出处： Critical reviews in oncology/hematology 2025

关键词： Antineoplastic treatment;Cancer screening;Clinical application;Liquid biopsy;Metastasis;Recurrence.

摘要： In recent years, liquid biopsy has gained prominence as an emerging biomarker in cancer research, providing critical insights into tumor biology and m ...

作者： Min Zhang  ^{1   2}, Jiali Wu  ^{1   2}, Yimin Wang  ³, Yidong Wu  ^{1   2}, Xiaoling Wan  ^{1   2}, Mei Jiang  ^{1   2}, Qiyu Bo  ^{1   2}, Jieqiong Chen  ^{1   2}, Xiaodong Sun  ^{1   2   4   5} （Affiliations ¹ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China. ² National Clinical Research Center for Ophthalmic Diseases, Shanghai, China. ³ Department of Ophthalmology, Zhongshan Hospital, Fudan University, Shanghai, China. ⁴ Shanghai Key Laboratory of Fundus Diseases, Shanghai, China. ⁵ Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China.）

出处： Aging cell 2025

关键词： EndMT;VASH1;circSIRT2;miR‐542‐3p;subretinal fibrosis.

摘要： Neovascular age-related macular degeneration (nAMD), characterized by choroidal neovascularization (CNV), is one of the leading causes of severe visua ...

作者： Qinqin Cai^1,2;Qiao Zhao^1,2;Qingxia Yang¹;Min Zhu¹;Fufen Meng¹CA1;Jihong Jiang³CA2 （¹Department of Anesthesiology, Xinjiang Medical University Affiliated Cancer Hospital, Urumqi, Xinjiang, China;²These authors contributed equally to this work.;³Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China）

出处： Experimental Cell Research 2025

关键词： Ku70;Ku86;P300;Diabetic kidney injury;Glomerular endothelial cell

摘要： Endothelial inflammation caused by hyperglycemia contributes to cardiovascular complications in patients with diabetes. Diabetic kidney injury (DKI) i ...

作者： Huibiao Deng  ¹, Peng Wang  ², Minxing Liu  ³ （Affiliations ¹ Department of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China. ² Department of Emergency, The First Affiliated Hospital of Soochow University, No.899, Pinghai Road, Gusu District, Suzhou City, Jiangsu Province, 215031, China. ³ Department of Emergency, The First Affiliated Hospital of Soochow University, No.899, Pinghai Road, Gusu District, Suzhou City, Jiangsu Province, 215031, China. minxingliu0921@163.com.）

出处： Journal of cardiothoracic surgery 2025

关键词： Intensive care unit;Prognostic value;Pulmonary hypertension.

摘要： Background: The impact of pulmonary hypertension (PH) on critically ill patients has not been fully understood. Our objective was to explore the possi ...

作者： Meng-Qi Zhao  ^{1   2   3}, Miao-Yan Fan  ^{2   3}, Meng-Yan Cui  ^{2   3}, Su-Min Chen  ¹, Jing-Jing Wang  ³, Ying-Ying Lu  ^{4   5}, Qiao-Li Jiang  ⁶ （Affiliations ¹ Department of Gastroenterology, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 800 Huangjiahuayuan Road, Shanghai, 201803, China. ² Department of Gastroenterology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 201620, China. ³ Shanghai Key Laboratory of Pancreatic Diseases, Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China. ⁴ Department of Gastroenterology, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 800 Huangjiahuayuan Road, Shanghai, 201803, China. le_voyageur@sjtu.edu.cn. ⁵ Department of Gastroenterology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 201620, China. le_voyageur@sjtu.edu.cn. ⁶ Department of Gastroenterology, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 800 Huangjiahuayuan Road, Shanghai, 201803, China. mqzh0547@sjtu.edu.cn.）

出处： Gut pathogens 2025

关键词： Acute pancreatitis;Candida;Fungal diversity;Fungi;Gut microbiota.

摘要： Objective: The gut is involved in the development of acute pancreatitis (AP). Increased focus is being given to the role of gut microbiota in the path ...

作者： Junying Wei  ¹, Heshan Cao  ², Mingling Peng  ¹, Yinzhou Zhang  ³, Sibei Li  ⁴, Wuhua Ma  ⁵, Yuhui Li  ⁵ （Affiliations ¹ First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China. ² Department of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China. ³ Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China. ⁴ Department of Anesthesiology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China. ⁵ Department of Anesthesiology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.）

出处： PloS one 2025

摘要： Background: Ventilator-associated pneumonia (VAP) is a common nosocomial infection in ICU, significantly associated with poor outcomes. However, there ...

作者： Ruqiang Yuan ^{#  1}, Mingjing Gao ^{#  2   3}, Hu Xu ^{#  4}, Qing Liang  ¹, Lei Qian  ¹, Yali Wang  ¹, Houli Zhang  ⁵, Erjiao Qiang  ⁶, Weijing Yun  ⁷ （Affiliations ¹ Advanced Institute for Medical Sciences, Dalian Medical University, Dalian, 116044, China. ² Department of Pharmacy, Dalian Port Hospital, Dalian, 116001, China. ³ College of Pharmacy, Dalian Medical University, Dalian, 116044, China. ⁴ Wuhu Hospital and Health Science Center, East China Normal University, Shanghai, 200241, China. ⁵ College of Pharmacy, Dalian Medical University, Dalian, 116044, China. houlizh@163.com. ⁶ Department of Pathology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, China. qiangerjiao@126.com. ⁷ Advanced Institute for Medical Sciences, Dalian Medical University, Dalian, 116044, China. yunweijing@dmu.edu.cn.）

出处： BMC cardiovascular disorders 2025

关键词： Calcium influx;Alantolactone;Hypertension;Voltage-gated Calcium Channels.

摘要： Background: The dried root of Inula helenium L., known as Inulae Radix in Mongolian medicine, is a widely used heat-clearing plant drug within the Ast ...

作者： Ying Zhang ^{#  1   2   3}, Yan Ma ^{#  1   2}, Yu-Ke Ji ^{#  1   2}, Yi-Fei Jiang  ^{1   2}, Duo Li  ^{1   2}, Wan Mu  ⁴, Mu-Di Yao  ⁵, Jin Yao  ^{6   7}, Biao Yan  ⁸ （Affiliations ¹ The Affiliated Eye Hospital, Nanjing Medical University, Nanjing, 210000, China. ² The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, 210000, China. ³ Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200080, China. ⁴ Eye Institute, Department of Ophthalmology, Eye and ENT Hospital, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, 200030, China. ⁵ Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200080, China. mudiyao@163.com. ⁶ The Affiliated Eye Hospital, Nanjing Medical University, Nanjing, 210000, China. jinyao1972@126.com. ⁷ The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, 210000, China. jinyao1972@126.com. ⁸ Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200080, China. yanbiao@sjtu.edu.cn.）

出处： Cell communication and signaling : CCS 2025

关键词： Ischemic/reperfusion injury;Müller cells;Reactive gliosis;Retinal ganglion cells;tsRNA.

摘要： Ischemic retinopathies are the major causes of blindness, yet effective early-stage treatments remain limited due to an incomplete understanding of th ...

作者： Jiandong Zhou  ¹, Yunshan Guo  ¹, Xuan Liu  ¹, Weijie Yuan  ¹ （Affiliation ¹ Department of Nephrology, Shanghai General Hospital of Nanjing Medical University, Shanghai, China.）

出处： Adipocyte 2025

关键词： Secretory proteins;adipose tissue;bioinformatics;epigenetics;metabolic syndrome.

摘要： The objective of this study was to identify key secretory protein-encoding differentially expressed genes (SP-DEGs) in adipose tissue in female metabo ...

作者： Wei Chen  ¹, Yuanjun Tang  ², Yachen Si  ¹, Boxiang Tu  ³, Fuchuan Xiao  ⁴, Xiaolu Bian  ¹, Ying Xu  ¹, Yingyi Qin  ³ （Affiliations ¹ Department of Nephrology, Shanghai Changhai Hospital, Shanghai 200433, China. ² Department of Clinical Pharmacy, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200240, China. ³ Department of Military Health Statistics, Naval Medical University, Shanghai 200433, China. ⁴ Navy No. 929 Hospital, Shanghai 200433, China.）

出处： Journal of translational internal medicine 2025

关键词： all-cause mortality;chronic kidney disease;life’s essential 8.

摘要： Background and objectives: The association between chronic kidney disease (CKD) and cardiovascular disease has been previously evaluated. This study a ...