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作者: Jian Lin;Zhanjun Lu;Gengfeng Li;Cui Zhang;Huiying Lu;Sheng Gao;Ruixin Zhu;Hailiang Huang;Konrad Aden;Jianhua Wang;Yingzi Cong;Huili Wu;Zhanju Liu (1Department of Gastroenterology, Shanghai Tenth People’s Hospital of Tongji University School of Medicine, Shanghai, China;2Department of Gastroenterology, Affiliated Hospital of Putian University, Putian, China;3Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;4Department of Bioinformatics, School of Life Sciences and Technology, Tongji University, Shanghai, China;5Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA;6Department of Internal Medicine I, Institute of Clinical Molecular Biology, Christian-Albrechts-University, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany;7Storr Liver Unit, Westmead Millennium Institute, Westmead Hospital, University of Sydney, Sydney, New South Wales, Australia;8Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA;9Department of Gastroenterology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China)
出处: Journal of Innate Immunity 2023
关键词: MCPIP-1;Neutrophils;Acute bacterial peritonitis;Liver injury;Bacterial infection
摘要: Monocyte chemotactic protein-1-induced protein-1 (MCPIP-1) is highly expressed in activated immune cells and negatively regulates immune responses, wh ...
作者: Aoyuan Fan;Genbin Wu;Jianfang Wang;Laiya Lu;Jingyi Wang;Hanjing Wei;Yuxi Sun;Yanhua Xu;Chunyang Mo;Xiaoying Zhang;Zhiying Pang;Zhangyi Pan;Yiming Wang;Liangyu Lu;Guojian Fu;Mengqiu Ma;Qiaoling Zhu;Dandan Cao;Jiachen Qin;Feng Yin;Rui Yue (1Department of Joint Surgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200092, China;2Department of Orthopedic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200240, China;3Institute for Regenerative Medicine, Shanghai East Hospital, Frontier Science Center for Stem Cell Research, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China;4Department of Cardiology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, 200072, China;5Shanghai Institute of Stem Cell Research and Clinical Translation, Shanghai, 200120, China;6Shanghai Clinical Research Center for Aging and Medicine, Shanghai, 200040, China)
出处: Bone Research 2023
摘要: Fibroblast activation protein (Fap) is a serine protease that degrades denatured type I collagen, α2-antiplasmin and FGF21. Fap is highly expressed in ...
作者: Hongmiao Wang;Huixun Jia;Yang Gao;Haosong Zhang;Jin Fan;Lijie Zhang;Fandong Ren;Yandong Yin;Yuping Cai;Ji Zhu;Zheng-Jiang Zhu (1Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 200032, China;2University of Chinese Academy of Sciences, Beijing, 100049, China;3Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China;4Department of Biostatistics, Fudan University Shanghai Cancer Center, Shanghai, 200032, China;5Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, 310005, China;6Institute of Cancer and Basic Medicine, Chinese Academy of Sciences, Hangzhou, 310000, China;7Zhejiang Key Laboratory of Radiation Oncology, Hangzhou, 310000, China;8Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, 200032, China;9Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200031, China;10Shanghai Key Laboratory of Radiation Oncology, Shanghai, 200032, China;11Shanghai Key Laboratory of Aging Studies, Shanghai, 201210, China)
出处: Nature Communications 2023
作者: Fangfei Zhang;Jianyong Yin;Li Liu;Shuiying Liu;Guangyuan Zhang;Yiwei Kong;Yajun Wang;Niansong Wang;Xiangmei Chen;Feng Wang (Affiliations 1 Department of Rheumatology, Immunology and Allergy, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 Department of Nephrology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China. Electronic address: yinjianyong09@163.com. 3 Department of Urology, Zhongda Hospital, Southeast University, Nanjing, China. 4 Biomedical School, Medical College of Wisconsin, Milwaukee, Wisconsin, USA. 5 Department of Nephrology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China. 6 State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing, China. 7 Department of Rheumatology, Immunology and Allergy, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: zyzwq1030@hotmail.com.)
出处: EBioMedicine 2023
关键词: Acute kidney injury;Diabetic nephropathy;IL-17C;Ischemia/reperfusion injury.
摘要: Background: Interleukin-17C (IL-17C), a member of the IL-17 cytokine family, plays a pathogenic role in kidney diseases. Our previous studies have sho ...
作者: Meirong Yu;Shuang Wu;Chao Gong;Lianhua Chen (Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ; Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ; Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ; Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.)
出处: Frontiers in Pharmacology 2023
关键词: Neuregulin-1β;C2C12 myotubes;glucose uptake;GLUT4 translocation;PI3K/AKT
摘要: Insulin resistance (IR) is a feature of type 2 diabetes (T2DM) accompanied by reduced glucose uptake and glucose transporter 4 (GLUT4) translocation b ...
作者: Yinuo Wang;Junyao Zhang;Yingying Zhang;Junyan Yao (Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ; Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ; Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ; Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.)
出处: Frontiers in Endocrinology 2023
关键词: Ketogenic Diet;Neurological Diseases;bibliometric analysis;hotspots;Citespace;VOSviewer
摘要: BackgroundThe protective effects of Ketogenic Diet Therapies (KDTs) on neurological diseases have been extensively studied over the past two decades. ...
作者: Yan Zhou1;Yali Qiu2;Wuping Bao1;Lei Han1;Yishu Xue1;Yingying Zhang1;Xue Tian1;Qiang Fu1;Chengjian Lv1;Dongning Yin1;Min Zhang2 (1Department of Respiratory and Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;2Department of Respiratory and Critical Care Medicine, Shanghai General Hospital of Nanjing Medical University, Shanghai, China)
出处: Frontiers in Immunology 2023
关键词: vitamin D;airway inflammation;airway resistance;asthma endotypes;T2-low asthma
摘要: IntroductionAsthma is primarily divided into two categories: type 2 (T2-high) and non-type 2 (T2-low). A relationship between asthma severity and vita ...
作者: Jun Zhu1;Yingchi Shan1;Yihua Li1;Jiaqi Liu1;Xiang Wu1;Guoyi Gao1;Guoyi Gao2 (1Department of Neurosurgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;2Shanghai Head Trauma Institute, Shanghai, China)
出处: Frontiers in Physiology 2023
关键词: traumatic brain injury;prognosis;intracranial pressure;parameter;spindle wave
摘要: Objective: Intracranial pressure (ICP) monitoring is an integral part of the multimodality monitoring system in the neural intensive care unit. The pr ...
作者: Zeyi Wang;Zhengnan Huang;Xiangqian Cao;Fang Zhang;Jinming Cai;Pengfei Tang;Chenkai Yang;Shengzhou Li;Dong Yu;Yilin Yan;Bing Shen (Department of Urology, Shanghai General Hospital of Nanjing Medical University, Shanghai, 200080, China Department of Urology, Tongji Hospital, School of Medicine, Tongji University, Shanghai, 200065, China Department of Urology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, China Department of Precision Medicine, Center of Translation Medicine, Naval Medical University, Shanghai, 200082, China Department of Urology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, China)
出处: BMC Urology 2023
关键词: Bladder cancer;Necroptosis;Tumor immune microenvironment;Prognostic model;Immunotherapy;Chemotherapy
摘要: Bladder cancer, one of the most prevalent malignant cancers, has high rate of recurrence and metastasis. Owing to genomic instability and high-level h ...
作者:
Zhenguo Zi1,2;Shujuan Du3,2;Liming Zhang4,2;Yuebo Wang1;Ling Ding3;Chongqi Zhang1;Huanyu Wang1;Jan Pawlicki5;Yuan Cai6;Yazhou Yao7;Feng Zhou8;Yin Tong9;James L. Riley5;Qiliang Cai3
出处: Blood Advances 2023
关键词: Golgi membrane protein 1 (GOLM1);anaplastic large cell lymphoma (ALCL);anaplastic lymphoma kinase (ALK) ALCL;apoptosis;B-cell lymphoma-extra-large protein (BCL-XL)
摘要: Golgi membrane protein 1 (GOLM1) is aberrantly expressed in many types of solid tumors and contributes to cancer development; however, its role in hem ...
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