作者： Yang Li  ¹, Jun Cao  ^{1   2}, Jianfeng Wang  ¹, Weidong Wu  ¹, Liren Jiang  ³, Xing Sun  ¹ （Affiliations ¹ Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of General Surgery, Shanghai Jiangqiao Hospital, Shanghai General Hospital Jiading Branch, Shanghai, China. ³ Department of Pathology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Cancer 2023

关键词： IGF2BP3;brain metastasis;breast cancer;prognosis;tumor progression.

摘要： Background: This study aimed to determine the role of insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3), an N⁶ -methyladinosine ...

作者： Jingwen Chen ^{#  1}, Rong Cao ^{#  1}, Shengyin Jiao  ², Yunpeng Dong  ², Zilong Wang  ², Hua Zhu  ¹, Qian Luo  ¹, Lei Zhang  ¹, Han Wang  ¹, Xiaorui Yin  ¹ （Affiliations ¹ Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of R&D, VoxelCloud, Shanghai, China.）

出处： Quantitative imaging in medicine and surgery 2023

关键词： Artificial intelligence (AI);computer-aided diagnosis (CAD);convolutional neural network;nodule detection;pulmonary nodule.

摘要： Background: Computer-aided diagnosis (CAD) systems can help reduce radiologists' workload. This study assessed the value of a CAD system for the detec ...

作者： Feifan Chen ^{#  1}, Yinshi Huang ^{#  1}, Congying Chen  ¹, Yajing Zhang  ¹, Yiyi Zhang  ¹, Rong Wan  ¹, Min Xu  ¹ （Affiliation ¹ Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiaotong University, 200080, Shanghai, P.R. China.）

出处： Neuro endocrinology letters 2023

摘要： Objectives: To evaluate the magnetic resonance imaging (MRI) and computed tomography (CT) findings along with other surgical and pathologic features a ...

作者： Kun Wang  ¹, Yanan Lyu  ², Alexander V Tschulakow  ^{1   3}, Douglas E Brash  ^{4   5}, Ulrich Schraermeyer  ^{1   3} （Affiliations ¹ Division of Experimental Vitreoretinal Surgery, Centre for Ophthalmology, University of Tuebingen, Tuebingen 72076, Germany. ² Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200020, China. ³ Ocutox, Preclinical Drug Assessment, Hechingen 72379, Germany. ⁴ Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520-8040. ⁵ Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, CT 06520-8028.）

出处： Proceedings of the National Academy of Sciences of the United States of America 2023

作者： Bing Li  ¹, Jing-Yi Liu  ¹, Dong-Li He  ², Xin-Jian Wan  ³, Rong Wan  ⁴, Li-Qing Yao  ¹, Qiang Shi  ¹, Shi-Lun Cai  ¹, Zhi-Peng Qi  ¹, Zhong Ren  ¹, Ming-Yan Cai  ¹, Ping-Hong Zhou  ⁵, Yun-Shi Zhong  ⁶ （Affiliations ¹ Endoscopy Center, Zhongshan Hospital of Fudan University, Shanghai, China; Endoscopy Research Institute of Fudan University, Shanghai, China; Shanghai Collaborative Innovation Center of Endoscopy, Shanghai, China. ² Endoscopy Center, Xuhui Hospital, Zhongshan Hospital of Fudan University, Shanghai, China. ³ Department of Gastroenterology, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁴ Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁵ Endoscopy Center, Zhongshan Hospital of Fudan University, Shanghai, China; Endoscopy Research Institute of Fudan University, Shanghai, China; Shanghai Collaborative Innovation Center of Endoscopy, Shanghai, China. Electronic address: zhou.pinghong@zs-hospital.sh.cn. ⁶ Endoscopy Center, Zhongshan Hospital of Fudan University, Shanghai, China; Endoscopy Research Institute of Fudan University, Shanghai, China; Shanghai Collaborative Innovation Center of Endoscopy, Shanghai, China. Electronic address: zhongyunshi@yahoo.com.）

出处： Gastrointestinal endoscopy 2023

关键词： clinical score model;endoscopic submucosal dissection;model update;prospective validation;technical difficulty.

摘要： Background and aims: The Zhongshan CR-ESD Score model was proposed to grade the technical difficulty of colorectal endoscopic submucosal dissection (C ...

作者： Tong Zhu  ^{1   2}, Yingao Li  ^{1   2}, Lilin Zhu  ^{1   2}, Jinyuan Xu  ^{1   2}, Zijun Feng  ², Hao Chen  ³, Si Shi  ^{1   2}, Caiying Liu  ^{1   2}, Qingjian Ou  ^{1   4}, Furong Gao  ^{1   2}, Jieping Zhang  ^{1   4}, Caixia Jin  ^{1   2}, Jingying Xu  ^{1   2}, Jiao Li  ², Jingfa Zhang  ⁵, Yanlong Bi  ¹, Guo-Tong Xu  ^{1   4}, Juan Wang  ^{1   6}, Haibin Tian  ^{1   2}, Lixia Lu  ^{1   2} （Affiliations ¹ Department of Ophthalmology of Shanghai Tongji Hospital, Laboratory of Clinical Visual Science of Tongji Eye Institute, School of Medicine, Tongji University, Shanghai, China. ² Department of Biochemistry and Molecular Biology, Tongji University School of Medicine, Shanghai, China. ³ Department of Ophthalmology of Shanghai Tenth People's Hospital, Tongji University, Shanghai, China. ⁴ Department of Pharmacology, Tongji University School of Medicine, Shanghai, China. ⁵ Department of Ophthalmology of Shanghai First People's Hospital, Shanghai Jiaotong University, Shanghai, China. ⁶ Department of Human Genetics, Tongji University School of Medicine, Shanghai, China.）

出处： Glia 2023

关键词： diabetic retinopathy;glia maturation factor β;retinal degeneration.

摘要： Retinal degeneration, characterized by Müller cell gliosis and photoreceptor apoptosis, is considered an early event in diabetic retinopathy (DR). Our ...

作者： Yuanyuan Liu ^{#  1}, Xing Wang ^{#  2   3}, Yuying Liu ^{#  1}, Jianqiang Yang  ⁴, Wei Mao  ¹, Chen Feng  ¹, Xiaoliang Wu  ⁵, Xinwei Chen  ⁶, Lixiao Chen  ⁷, Pin Dong  ⁸ （Affiliations ¹ Department of Otolaryngology: Head and Neck Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. ² Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, 330046, China. ³ Centre for Medical Research and Translation, Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, 330006, China. ⁴ Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, School of Medicine, Atlanta, GA, 30322, USA. ⁵ Department of Oncology, Shenzhen Hospital of Southern Medical University, Shenzhen, 510086, China. ⁶ Department of Otolaryngology: Head and Neck Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. xinwei.chen@shgh.cn. ⁷ Department of Otolaryngology: Head and Neck Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. Chenlixiao1201@163.com. ⁸ Department of Otolaryngology: Head and Neck Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. dongpin64@aliyun.com.）

出处： Cell death & disease 2023

摘要： N4-acetylcytidine (ac4C) is a post-transcriptional RNA modification that regulates in various important biological processes. However, its role in hum ...

作者： Zhicheng Dai  ¹, Yanan Chen  ¹, Enjun He  ¹, Hongjie Wang  ¹, Weihong Guo  ¹, Zhenkai Wu  ², Kai Huang  ³, Qinghua Zhao  ¹ （Affiliations ¹ Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of Pediatric Orthopaedics, Shanghai Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ Department of Orthopedics, Zhabei Central Hospital of Jing'an District, Shanghai, China.）

出处： Bone & joint research 2023

摘要： Aims: Osteoporosis is characterized by decreased trabecular bone volume, and microarchitectural deterioration in the medullary cavity. Interleukin-19 ...

作者： Hao Wu ^{#  1   2}, Yicheng Lu ^{#  2}, Zhenzhen Duan ^{#  2}, Jingni Wu  ², Minghui Lin  ², Yangjun Wu  ³, Siyang Han  ⁴, Tongqi Li  ⁴, Yuqi Fan  ⁵, Xiaoyuan Hu  ⁶, Hongyan Xiao  ⁷, Jiaxuan Feng  ⁸, Zhiqian Lu  ⁹, Deping Kong  ¹⁰, Shengli Li  ¹¹ （Affiliations ¹ Department of Cardiovascular Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Precision Research Center for Refractory Diseases, Institute for Clinical Research, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ Department of Gynecological Oncology, Fudan University Shanghai Cancer Center, Shanghai, China. ⁴ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁵ North Cross School Shanghai, Shanghai, China. ⁶ H. Milton Stewart School of Industrial and Systems Engineering, College of Engineering, Geogia Institute of Technology, Atlanta, GA, USA. ⁷ Department of Cardiac Surgery, Wuhan Asia Heart Hospital, Wuhan University of Science and Technology, Wuhan, China. ⁸ Department of Vascular Surgery and Intervention Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁹ Department of Cardiovascular Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. 18930177678@163.com. ¹⁰ Precision Research Center for Refractory Diseases, Institute for Clinical Research, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. deping.kong@shsmu.edu.cn. ¹¹ Precision Research Center for Refractory Diseases, Institute for Clinical Research, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. shengli.li@sjtu.edu.cn.）

出处： Communications biology 2023

摘要： Vascular smooth muscle cells (VSMCs) are the major contributor to vascular repair and remodeling, which showed high level of phenotypic plasticity. Ab ...

作者： Yaxin Fan ^{#  1   2   3}, Kaiting Zhang ^{#  1   2   3}, Mengting Chen  ^{1   2   3}, Nanyang Li  ⁴, Xiaofen Liu  ^{1   2   3}, Minjie Yang  ^{1   2   3}, Xiaoyu Liang  ^{1   2   3}, Jufang Wu  ^{1   2   3   4}, Beining Guo  ^{1   2   3}, Huajun Zheng  ⁵, Yongqiang Zhu  ⁵, Fengying Zhang  ⁶, Jingqing Hang  ⁶, Huifang Zhang  ⁷, Ruilan Wang  ⁷, Qing Yuan  ⁸, Xiaolian Song  ⁸, Shengbin Wu  ⁹, Bo Shen  ⁹, Jing Zhang  ^{1   2   3} （Affiliations ¹ Institute of Antibiotics, Huashan Hospital, Fudan University , Shanghai, China. ² Key Laboratory of Clinical Pharmacology of Antibiotics, National Population and Family Planning Commission , Shanghai, China. ³ National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University , Shanghai, China. ⁴ Phase I Clinical Research Center, Huashan Hospital, Fudan University , Shanghai, China. ⁵ Shanghai-MOST Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center at Shanghai and Shanghai Institute for Biomedical and Pharmaceutical Technologies , Shanghai, China. ⁶ Department of Pulmonary Medicine, Shanghai Putuo District People's Hospital , Shanghai, China. ⁷ Emergency and Critical Care Department, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai, China. ⁸ Department of Respiratory and Critical Care Medicine, Tenth People's Hospital of Tongji University , Shanghai, China. ⁹ Department of Nephrology, Shanghai Ninth People's Hospital , Shanghai, China.）

出处： mSphere 2023

关键词： ST5;ST764;efficacy;methicillin-resistant Staphylococcus aureus;vancomycin.

摘要： This study compared the impact of sequence type 5 (ST5) and ST764, on the efficacy of vancomycin treatment in methicillin-resistant Staphylococcus aur ...