作者： Yihan Zhang  ¹, Xin Xie  ², Hong Zhou  ¹, Bingxin Li  ¹, Li Ding  ³, Zhaogen Cai  ³, Huaidong Song  ⁴, Shuangxia Zhao  ⁴, Huanbai Xu  ¹ （Affiliations ¹ Department of Endocrinology and Metabolism, Center for Microbiota and Immunological Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of Endocrinology and Metabolism, Shanghai Traditional Chinese and Medicine Integrated Hospital, Shanghai, China. ³ Department of Pathology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China. ⁴ Department of Molecular Diagnostics & Endocrinology, The Core Laboratory in Medical Center of Clinical Research, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Frontiers in endocrinology 2023

关键词： Hashimoto autoimmune thyroiditis;SERPINA1;gene set enrichment analyses (GSEA);papillary thyroid cancer;weighted gene co- expression network analyses (WGCNA).

摘要： Background: Hashimoto's thyroiditis (HT) is an autoimmune thyroid disease. Papillary thyroid carcinoma (PTC) is the most common endocrine cancer. In r ...

作者： Ye Yang;Jun Liu;Xiaoqin Shi;Min Wang （Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China Department of Pathology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China）

出处： Cancer Control 2023

摘要： Background Papillary thyroid carcinoma (PTC) is the most common subtype of thyroid carcinoma, and Hashimoto’s thyroiditis (HT) has been postulated to ...

作者： Hao Wu¹²;Yicheng Lu²;Zhenzhen Duan²;Jingni Wu²;Minghui Lin²;Yangjun Wu³;Siyang Han⁴;Tongqi Li⁴;Yuqi Fan⁵;Xiaoyuan Hu⁶;Hongyan Xiao⁷;Jiaxuan Feng⁸;Zhiqian Lu¹CA1;Deping Kong²CA2;null;Shengli Li²CA3 （¹Department of Cardiovascular Surgery, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China;²Precision Research Center for Refractory Diseases, Institute for Clinical Research, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;³Department of Gynecological Oncology, Fudan University Shanghai Cancer Center, Shanghai, China;⁴Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;⁵North Cross School Shanghai, Shanghai, China;⁶H. Milton Stewart School of Industrial and Systems Engineering, College of Engineering, Geogia Institute of Technology, Atlanta, GA, USA;⁷Department of Cardiac Surgery, Wuhan Asia Heart Hospital, Wuhan University of Science and Technology, Wuhan, China;⁸Department of Vascular Surgery and Intervention Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China）

出处： Communications Biology 2023

摘要： Vascular smooth muscle cells (VSMCs) are the major contributor to vascular repair and remodeling, which showed high level of phenotypic plasticity. Ab ...

作者： Yingting Zhang¹;Xidai Long²;Xin Ruan¹;Qian Wei¹;Lin Zhang³;Lulu Wo¹;Dongdong Huang¹;Longshuai Lin⁴;Difei Wang¹;Li Xia⁵;Qinghua Zhao⁴;Junling Liu³;Qian Zhao¹CA1;null;Ming He¹CA2 （¹Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China;²Department of Pathology, The Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, China;³Department of Biochemistry and Molecular Cell Biology, Key Laboratory of Cell Differentiation and Apoptosis of the Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China;⁴Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China;⁵Department of Core Facility of Basic Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China）

出处： Cell Discovery 2023

作者： Yuanyuan Liu¹;Xing Wang²³;Yuying Liu¹;Jianqiang Yang⁴;Wei Mao¹;Chen Feng¹;Xiaoliang Wu⁵;Xinwei Chen¹CA1;Lixiao Chen¹CA2;null;Pin Dong¹CA3 （¹Department of Otolaryngology: Head and Neck Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China;²Jiangxi Provincial People’s Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, 330046, China;³Centre for Medical Research and Translation, Jiangxi Provincial People’s Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, 330006, China;⁴Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, School of Medicine, Atlanta, GA, 30322, USA;⁵Department of Oncology, Shenzhen Hospital of Southern Medical University, Shenzhen, 510086, China）

出处： Cell Death & Disease 2023

摘要： N4-acetylcytidine (ac4C) is a post-transcriptional RNA modification that regulates in various important biological processes. However, its role in hum ...

作者： Kangli Ma;Shu Li;Sufang Wu;Jingfen Zhu;Yongbin Yang （Affiliations ¹ Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China. ² School of Public Health, Shanghai Jiao Tong University, Shanghai, People's Republic of China.）

出处： Tobacco induced diseases 2023

关键词： human papillomavirus;normal uterine cervix;persistent infection;smoking.

摘要： Introduction: Smoking has been proven to increase the risk of cervical cancer, but it is still controversial whether smoking reduces women's ability t ...

作者： Fei Shi;Changqing Yang;Qingxin Jiang;Weifang Zhu;Xun Xu;Xinjian Chen;Ying Fan （Affiliations ¹ Electronics and Information Engineering, Soochow University, 1 Shizi Street, Suzhou, 215006, CHINA. ² Soochow University, 1 Shizi Street, Suzhou, Jiangsu, 215006, CHINA. ³ Shanghai General Hospital, No. 100 Haining Road, Shanghai, 200080, CHINA.）

出处： Physics in medicine and biology 2023

关键词： Deep learning;Multi-class segmentation;OCT image;Retinal detachment;Retinoschisis.

摘要： Retinal detachment (RD) and retinoschisis (RS) are the main complications leading to vision loss in high myopia. Accurate segmentation of RD and RS, i ...

作者： Hanhao Dai  ¹, Jun Luo  ², Lili Deng  ³, Chao Song  ¹, Zhibo Deng  ¹, Yijing Wu  ¹, Song Gu  ⁴, Jie Xu  ^{1   2} （Affiliations ¹ Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350000, China. ² Department of Orthopedics, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, 350000, China. ³ State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai, 201620, China. ⁴ Trauma Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China.）

出处： Advanced healthcare materials 2023

关键词： Extracellular vesicle;MicroRNA;Myogenesis;Sarcopenia;Stemness.

摘要： Sarcopenia is a geriatric disease characterized by reduced muscle function and mass. The capacity to self-renew and myogenesis of satellite cells (SCs ...

作者： Yi Zheng¹;Jing Chen¹;Xin-Ran Song²;Mei-Qi Chang³;Wei Feng²;Hui Huang²;Cai-Xia Jia¹;Li Ding⁴CA1;Yu Chen²CA2;Rong Wu¹CA3 （¹Department of Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, PR China;²Materdicine Lab, School of Life Sciences, Shanghai University, Shanghai, 200444, PR China;³Central Laboratory of Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200071, PR China;⁴Department of Medical Ultrasound, Shanghai Tenth People's Hospital, Ultrasound Research and Education Institute, Tongji University Cancer Center, Shanghai Engineering Research Center of Ultrasound Diagnosis and Treatment, Tongji University School of Medicine, Tongji University, Shanghai, 200070, PR China）

出处： Biomaterials 2023

关键词： Antitumor immunotherapy;Innate immunity;Manganese;Synergistic therapy;cGAS-STING pathway

摘要： As the clinical efficacy of immunotherapy for triple-negative breast cancer (TNBC) remains limited, exploring new immunotherapy approaches is still in ...

作者： Senmiao Zhu^1,2,3,4;Lili Chen^1,2,4;Min Wang^1,2,3,4;Jing Zhang²;Gang Chen²;Yinghao Yao⁵;Shihan Song^1,2;Tong Li²;Shenglan Xu²;Zhonghao Yu^1,2;Bingyan Shen^1,2;Duogang Xu⁶;Zai-Long Chi^1,2CA1;Wencan Wu^1,2,3CA2 （¹National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China;²State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China;³Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou, Zhejiang 325000, China;⁴These authors contributed equally to this work.;⁵Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325027, China;⁶Department of General Surgery, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200080, China）

出处： Journal of Controlled Release 2023

关键词： Schwann cells;Optic neuropathy;Small extracellular vesicles;Natural biomaterials;Retinal ganglion cells;CREB signaling pathway

摘要： Optic neuropathy is the leading cause of irreversible blindness and is characterized by progressive degeneration of retinal ganglion cells (RGCs). Sev ...