作者： Meiling Wang  ¹, Qiqi Zhang  ², Jing Wang  ¹ （Affiliations ¹ Department of Gastroenterology, Songjiang Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Journal of gastroenterology and hepatology 2025

关键词： PCED1A;colorectal cancer;diagnostic marker;hepatocellular carcinoma;immune infiltration.

摘要： Background: Hepatocellular carcinoma (HCC) and colorectal cancer (CRC) pose a significant threat to human health worldwide, characterized by intricate ...

作者： Yuepeng An ^{#  1}, Fu Zhao ^{#  2}, Hongling Jia ^{#  3}, Siyu Meng  ⁴, Ziwei Zhang ^{#  5}, Shuxiao Li ^{#  6   7}, Jiusi Zhao ^{#  8} （Affiliations ¹ The First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, 150040, China. ² Shandong University of Traditional Chinese Medicine, Jinan, 250014, China. ³ The First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, 250014, Shandong, China. ⁴ Northeast International Hospital, Shenyang, 110180, China. ⁵ Department of Plastic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China. andreavaimukas@sjtu.edu.cn. ⁶ Department of Burns and Plastic Reconstructive Surgery, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, 533000, Guangxi Province, China. 977817863@qq.com. ⁷ Life Science and Clinical Medicine Research Center, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, 533000, Guangxi Province, China. 977817863@qq.com. ⁸ The First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, 150040, China. zjs_0807999@163.com.）

出处： Discover oncology 2025

关键词： Macrophages;Melanoma;Oxidative phosphorylation;Programmed cell death;Single-cell RNA sequencing;Tumor metastasis.

摘要： Melanoma is an aggressive type of skin cancer that arises from melanocytes, the cells responsible for producing skin pigment. In contrast to non-melan ...

作者： Shiyi He  ¹, Chenxi Wang  ², Wenqing Shi  ³, Chunyan Zhou  ⁴, Chenxi Liu  ¹, Ying Xu  ⁵, Xinhui Jiang  ¹, Yaxing Gui  ⁶, Guorong Fan  ⁷ （Affiliations ¹ Chongqing Medical University, School of Pharmacy, No.1 Yixueyuan Road, Yuzhong District, Chongqing, 400016, PR China, Chongqing, CHINA. ² Shanghai Fourth People's Hospital Affiliated to Tongji University: Shanghai Fourth People's Hospital, Department of Clinical Pharmacy, No.1279 Sanmen Road, Shanghai 200434, PR China, Shanghai, CHINA. ³ Shanghai Fourth People's Hospital Affiliated to Tongji University: Shanghai Fourth People's Hospital, Department of Pharmacy, No.1279 Sanmen Road, Shanghai 200434, PR China, Shanghai, CHINA. ⁴ Kunming Medical University, School of Pharmacy, No. 1168 Chunrong West Road, Yuhua Street, Chenggong District, Yunnan, Yunnan, CHINA. ⁵ Shanghai General Hospital, Department of Neurology,, 85 Wujin Road, Hongkou District, Shanghai, Shanghai, CHINA. ⁶ Shanghai General Hospital, Department of Neurology, 85 Wujin Road, Hongkou District, Shanghai, Shanghai, CHINA. ⁷ Shanghai General Hospital, department of clinical Pharmacy, 85 Wujin Road, Hongkou District, Shanghai, 200080, Shanghai, CHINA.）

出处： Chemistry & biodiversity 2025

关键词： UPLC-Q-TOF-MS/MS;lotus;molecular docking;network pharmacology;sleep.

摘要： Lotus leaves (LL), petals (LP), and seeds (LS) are believed to have properties that can improve sleep. However, their efficacy in improving sleep has ...

作者： Longmei Wu  ^{1   2}, Huayan Yin  ¹, Lingfang Guan  ¹, Guanjian Li  ^{1   3   4   5}, Junqiang Zhang  ^{1   3   4   5}, Qunshan Shen  ^{1   3   4   5}, Xiaoqing Ni  ^{1   3   4   5}, Chao Wang  ^{1   3   4   5}, Tianjuan Wang  ^{1   3   4   5}, Hao Geng  ^{1   3   4   5}, Chuan Xu  ^{1   3   4   5}, Yunxia Cao  ^{6   7   8   9}, Xiaojin He  ^{10   11   12}, Bing Song  ^{13   14   15   16} （Affiliations ¹ Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China. ² Department of Obstetrics and Gynecology, Anhui Public Health Clinical Center, Hefei, 230032, China. ³ NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei, 230032, China. ⁴ Anhui Province Key Laboratory of Reproductive Health and Genetics, Hefei, 230032, China. ⁵ Biopreservation and Artificial Organs, Anhui Provincial Engineering Research Center, Anhui Medical University, Hefei, 230032, China. ⁶ Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China. caoyunxia6@126.com. ⁷ NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei, 230032, China. caoyunxia6@126.com. ⁸ Anhui Province Key Laboratory of Reproductive Health and Genetics, Hefei, 230032, China. caoyunxia6@126.com. ⁹ Biopreservation and Artificial Organs, Anhui Provincial Engineering Research Center, Anhui Medical University, Hefei, 230032, China. caoyunxia6@126.com. ¹⁰ Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China. hxj0117@126.com. ¹¹ NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei, 230032, China. hxj0117@126.com. ¹² Reproductive Medicine Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. hxj0117@126.com. ¹³ Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China. songbing060907@126.com. ¹⁴ NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei, 230032, China. songbing060907@126.com. ¹⁵ Anhui Province Key Laboratory of Reproductive Health and Genetics, Hefei, 230032, China. songbing060907@126.com. ¹⁶ Biopreservation and Artificial Organs, Anhui Provincial Engineering Research Center, Anhui Medical University, Hefei, 230032, China. songbing060907@126.com.）

出处： Scientific reports 2025

关键词： Embryo transfer;In vitro fertilization;Ovarian stimulation;rhFSH-CTP.

摘要： We assessed the safety and efficacy of rhFSH-CTP, a novel long-acting FSH agent, in controlled ovarian hyperstimulation for patients undergoing ART. A ...

作者： Ting Shen  ^{1   2   3}, Samran Sheriff  ⁴, Yanlin Qu  ⁵, Vivek K Gupta  ⁴, Stuart L Graham  ^{4   6}, Alexander Klistorner  ^{4   6}, Huixun Jia  ^{7   8}, Xiaodong Sun  ⁹, Yuyi You  ^{10   11} （Affiliations ¹ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China. drshenting@126.com. ² Macquarie Medical School, Macquarie University, Sydney, NSW, Australia. drshenting@126.com. ³ Save Sight Institute, The University of Sydney, Sydney, NSW, Australia. drshenting@126.com. ⁴ Macquarie Medical School, Macquarie University, Sydney, NSW, Australia. ⁵ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China. ⁶ Save Sight Institute, The University of Sydney, Sydney, NSW, Australia. ⁷ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China. jiahuixun@163.com. ⁸ School of Public Health, Key Laboratory of Public Health Safety and Collaborative Innovation Center of Social Risks Governance in Health, Fudan University, Shanghai, China. jiahuixun@163.com. ⁹ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China. xdsun@sjtu.edu.cn. ¹⁰ Macquarie Medical School, Macquarie University, Sydney, NSW, Australia. yuyi.you@gmail.com. ¹¹ Save Sight Institute, The University of Sydney, Sydney, NSW, Australia. yuyi.you@gmail.com.）

出处： Brain imaging and behavior 2025

关键词： Axonal loss;Demyelination;Multiple sclerosis;Post-mortem;Quantitative MRI.

摘要： Magnetic resonance imaging (MRI) is frequently used to monitor disease progression in multiple sclerosis (MS). This study aims to systematically evalu ...

作者： Neng Chio Wong  ¹, Zhishan Hu  ², Wenhong Cheng  ^{1   3   4} （Affiliations ¹ Department of Child and Adolescent Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Neuroimaging Core, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ Department of Psychological Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁴ Shanghai Key Laboratory of Emotions and Affective Disorders, Shanghai, China.）

出处： PsyCh journal 2025

摘要： Using functional near-infrared spectroscopy technique, this study identified lower brain network efficiency in children with anxiety and/or depression ...

作者： Wei Liu ^{#  1   2   3}, Yufeng Zhu ^{#  4}, Wu Ye ^{#  4}, Junjun Xiong  ⁴, Haofan Wang  ⁴, Yu Gao  ⁴, Shixue Huang  ⁵, Yinuo Zhang  ⁵, Xin Zhou  ⁵, Xuhui Zhou  ^{6   7   8}, Xuhui Ge  ^{9   10   11}, Weihua Cai  ¹², Xingdong Zheng  ^{13   14} （Affiliations ¹ Department of Orthopedics, The Second Affiliated Hospital of Naval Medical University, Shanghai, 200003, China. liuweiorth@njmu.edu.cn. ² Department of Orthopedics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, Jiangsu, China. liuweiorth@njmu.edu.cn. ³ Department of Stress Medicine, Faculty of Psychology, Naval Medical University, Shanghai, 200433, China. liuweiorth@njmu.edu.cn. ⁴ Department of Orthopedics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, Jiangsu, China. ⁵ Department of Orthopedics, The Second Affiliated Hospital of Naval Medical University, Shanghai, 200003, China. ⁶ Department of Orthopedics, The Second Affiliated Hospital of Naval Medical University, Shanghai, 200003, China. zhouxuhui@smmu.edu.cn. ⁷ Department of Stress Medicine, Faculty of Psychology, Naval Medical University, Shanghai, 200433, China. zhouxuhui@smmu.edu.cn. ⁸ Translational Research Centre of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. zhouxuhui@smmu.edu.cn. ⁹ Department of Orthopedics, The Second Affiliated Hospital of Naval Medical University, Shanghai, 200003, China. georthopedics@163.com. ¹⁰ Department of Orthopedics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, Jiangsu, China. georthopedics@163.com. ¹¹ Department of Stress Medicine, Faculty of Psychology, Naval Medical University, Shanghai, 200433, China. georthopedics@163.com. ¹² Department of Orthopedics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, Jiangsu, China. caiwhspine@njmu.edu.cn. ¹³ Translational Research Centre of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. zhengxingdong2020@163.com. ¹⁴ Total Quality Management Institute, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. zhengxingdong2020@163.com.）

出处： Cell death and differentiation 2025

摘要： Ferroptosis is one of the cell death programs occurring after spinal cord injury (SCI) and is driven by iron-dependent phospholipid peroxidation. Howe ...

作者： Xixuan Zhao ^{#  1   2   3   4}, Yajun Peng ^{#  1}, Tao Yu ^{#  1}, Senlin Lin  ⁵, Hao Chen  ^{6   7}, Dan Qian  ⁸, Jianfeng Zhu  ¹, Yingnan Jia  ^{9   10}, Haidong Zou  ^{11   12   13   14}, Yingyan Ma  ^{15   16   17   18} （Affiliations ¹ Department of Eye Disease Control and Prevention, Shanghai Eye Disease Prevention & Treatment Center/Shanghai Eye Hospital, School of Medicine, Tongji University, No. 1440, Hongqiao Road, Shanghai, 200336, China. ² Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 100, Haining Road, Shanghai, 200080, China. ³ National Clinical Research Center for Eye Diseases, Shanghai, China. ⁴ Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China. ⁵ Department of Eye Disease Control and Prevention, Shanghai Eye Disease Prevention & Treatment Center/Shanghai Eye Hospital, School of Medicine, Tongji University, No. 1440, Hongqiao Road, Shanghai, 200336, China. woodylin@yeah.net. ⁶ Key Lab of Public Health Safety of the Ministry of Education, School of Public Health, Fudan University, 130 Dongan Road, Shanghai, 200032, China. ⁷ Health Communication Institute, Fudan University, Shanghai, 200032, China. ⁸ Eye and Dental Diseases Prevention and Treatment Center of Pudong New Area, Shanghai, China. ⁹ Key Lab of Public Health Safety of the Ministry of Education, School of Public Health, Fudan University, 130 Dongan Road, Shanghai, 200032, China. jyn@fudan.edu.cn. ¹⁰ Health Communication Institute, Fudan University, Shanghai, 200032, China. jyn@fudan.edu.cn. ¹¹ Department of Eye Disease Control and Prevention, Shanghai Eye Disease Prevention & Treatment Center/Shanghai Eye Hospital, School of Medicine, Tongji University, No. 1440, Hongqiao Road, Shanghai, 200336, China. zouhaidong@sjtu.edu.cn. ¹² Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 100, Haining Road, Shanghai, 200080, China. zouhaidong@sjtu.edu.cn. ¹³ National Clinical Research Center for Eye Diseases, Shanghai, China. zouhaidong@sjtu.edu.cn. ¹⁴ Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China. zouhaidong@sjtu.edu.cn. ¹⁵ Department of Eye Disease Control and Prevention, Shanghai Eye Disease Prevention & Treatment Center/Shanghai Eye Hospital, School of Medicine, Tongji University, No. 1440, Hongqiao Road, Shanghai, 200336, China. mYy_29@163.com. ¹⁶ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 100, Haining Road, Shanghai, 200080, China. mYy_29@163.com. ¹⁷ National Clinical Research Center for Eye Diseases, Shanghai, China. mYy_29@163.com. ¹⁸ Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China. mYy_29@163.com.）

出处： European journal of pediatrics 2025

关键词： Astigmatism;Children;Insufficient sleep;Refractive error.

摘要： The aim of this study is to examine the association between insufficient sleep and astigmatism, as well as its related refractive components, in presc ...

作者： Mengfei Wang ^{#  1}, Qin Yan ^{#  1}, Yunfeng Song ^{#  1}, Zhenbo Zhang  ², Xiaojun Chen  ³, Kun Gao  ⁴, Xiaoping Wan  ^{5   6} （Affiliations ¹ Department of Gynecology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, 201204, China. ² Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, 200080, China. ³ Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, 200011, China. ⁴ Department of Clinical Laboratory, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, 201204, China. kungao@tongji.edu.cn. ⁵ Department of Gynecology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, 201204, China. Wanxiaoping@tongji.edu.cn. ⁶ Shanghai Key Laboratory of Maternal and Fetal Medicine, Shanghai First Maternity and Infant Hospital, Shanghai, China. Wanxiaoping@tongji.edu.cn.）

出处： Oncogene 2025

作者： Wenyi Gan  ^{1   2}, Jianfeng Ouyang  ¹, Guorong She  ², Zhaowen Xue  ², Lingxuan Zhu  ³, Anqi Lin  ³, Weiming Mou  ⁴, Aimin Jiang  ⁵, Chang Qi  ⁶, Quan Cheng  ⁷, Peng Luo  ³, Hua Li  ⁸, Xiaofei Zheng  ² （Affiliations ¹ Department of Joint Surgery and Sports Medicine, Zhuhai People's Hospital Zhuhai hospital affiliated with Jinan University, Zhuhai, Guangdong, China. ² Department of Bone and Joint Surgery and Sports Medicine Center, The First Affiliated Hospital, The First Affiliated Hospital of Jinan University, Guangzhou, China. ³ Department of Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China. ⁴ Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁵ Department of Urology, Changhai hospital, Naval Medical University (Second Military Medical University), Shanghai, China. ⁶ The University of Hong Kong, Hong Kong, China. ⁷ Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, China. ⁸ Department of Orthopaedic, Jishuitan Hospital, Capital Medical University, Beijing, China.）

出处： International journal of surgery (London, England) 2025

摘要： Background: Recent advancements in artificial intelligence (AI) like ChatGPT have expanded possibilities for patient education, yet its impact on peri ...