作者： C R Wang  ¹, M Kang  ², J Xu  ¹, Y Lyu  ¹, Y F Jiang  ¹, M X Sun  ¹, D Q Zuo  ¹, J K Shen  ¹, X J Ma  ¹, W Sun  ¹, Y Q Hua  ², Zhengdong Cai  ¹ （Affiliations ¹ Department of Bone Tumor, Shanghai General Hospital, Shanghai 200080, China. ² Department of Bone Tumor, Shanghai General Hospital, Shanghai 200080, China Shanghai Cell Therapy Clinical Transformation Engineering Technology Research Center, Shanghai 200080, China.）

出处： Zhonghua yi xue za zhi 2022

摘要： Objective: To explore the safety and efficacy of tumor-infiltrating lymphocytes (TILs) extracted from tumor tissue in patients with pulmonary metastas ...

作者： Tianyu Qin ^{#  1   2}, Junpeng Fan ^{#  1   2}, Funian Lu  ^{1   2}, Li Zhang  ^{1   2}, Chen Liu  ^{1   2   3}, Qiyue Xiong  ^{1   2}, Yang Zhao  ⁴, Gang Chen  ^{5   6}, Chaoyang Sun  ^{7   8} （Affiliations ¹ Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Research building of Tongji Hospital, No.2 Jiankang Avenue, Caidian Street, Caidian District, Wuhan, 430030, China. ² Cancer Biology Research Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. ³ Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai, 200000, China. ⁴ Department of Plastic Cosmetic and Burn Surgery, Taihe Hospital, Hubei University of Medicine, Shiyan, 442008, China. ⁵ Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Research building of Tongji Hospital, No.2 Jiankang Avenue, Caidian Street, Caidian District, Wuhan, 430030, China. gumpc@126.com. ⁶ Cancer Biology Research Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. gumpc@126.com. ⁷ Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Research building of Tongji Hospital, No.2 Jiankang Avenue, Caidian Street, Caidian District, Wuhan, 430030, China. suncydoctor@gmail.com. ⁸ Cancer Biology Research Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. suncydoctor@gmail.com.）

出处： Journal of experimental & clinical cancer research : CR 2022

关键词： Genetically engineered mouse models;Ovarian cancer;Patient-derived organoids;Patient-derived xenograft;Personalised medicine;Preclinical models

摘要： Ovarian cancer (OC) is a heterogeneous malignancy with various etiology, histopathology, and biological feature. Despite accumulating understanding of ...

作者： H D Zou  ¹, L N Lu  ¹, Y Xu  ¹, S L Lin  ¹ （Affiliation ¹ Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai Vision Health Center & Shanghai Children Myopia Institute, Division of Ophthalmology Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai 200040, China.）

出处： [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 2022

摘要： Due to factors such as medical resources, public awareness, funding for general screening, or optimized screening models, community-based screening is ...

作者： T Li  ¹, C H Yang  ², H D Zou  ¹ （Affiliations ¹ Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai Vision Health Center & Shanghai Children Myopia Institute, Division of Ophthalmology Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai 200040, China. ² The Pediatric Hospital Affiliated to Fudan University, Shanghai 201102, China.）

出处： [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 2022

摘要： Two adolescents with T1DM participated in the Shanghai Children and Adolescent DM Eye study (SCADE) 2017-2018. The previous T1DM history of the 2 chil ...

作者： Björn Hegner  ^{1   2}, Tobias Kretzschmar  ³, Nan Zhu  ^{1   4}, Gunnar Kleinau  ⁵, Hongfan Zhao  ¹, Julian Kamhieh-Milz  ⁶, Julia Hilger  ⁷, Ralf Schindler  ^{1   8}, Patrick Scheerer  ^{5   9}, Gabriela Riemekasten  ¹⁰, Aurélie Philippe  ^{1   11}, Rusan Catar  ¹ （Affiliations ¹ Department of Nephrology and Critical Care Medicine, Campus Virchow Klinikum, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany. ² Vitanas Hospital for Geriatric Medicine, Berlin, Germany. ³ Department of Internal Medicine Emergency Care, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany. ⁴ Shanghai general hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China. ⁵ Institute of Medical Physics and Biophysics, Group Protein X-ray Crystallography and Signal Transduction, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany. ⁶ Department of Transfusion Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany. ⁷ Department of Rheumatology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany. ⁸ Nierenzentrum Zehlendorf, Berlin, Germany. ⁹ DZHK (German Centre for Cardiovascular Research), partner site Berlin. ¹⁰ Department of Rheumatology and Clinical Immunology, Universitätsklinikum Schleswig-Holstein, Lübeck, Germany. ¹¹ BIH Biomedical Innovation Academy, Berlin Institute of Health at Charité - Universitätsmedizin Berlin (BIH), Berlin, Germany.）

出处： Rheumatology (Oxford, England) 2022

关键词： G-protein coupled receptors;Scleroderma renal crisis;agonistic autoantibodies;receptor hypersensitization

摘要： Objectives: Scleroderma renal crisis (SRC) is a rare vascular complication of systemic sclerosis with substantial risks for end-stage renal disease an ...

作者： Zhenzhen Wei  ^{1   2}, Jing Zhou  ¹, Hao Yu  ¹, Yunzhou Pu  ¹, Yuelei Cheng  ¹, Yi Zhang  ¹, Qing Ji  ¹, Huirong Zhu  ¹ （Affiliations ¹ Department of Medical Oncology & Cancer Institute of Integrative Medicine, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. ² Medical Experiment Center, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201803, China.）

出处： Evidence-based complementary and alternative medicine : eCAM 2022

摘要： Background: Oxaliplatin (L-OHP) is a common chemotherapy drug used in the treatment of colorectal cancer (CRC). Our previous work showed that Zuo Jin ...

作者： Xiushi Ni  ¹, Fang Wu  ², Juan Song  ³, Lina An  ¹, Qianwen Jiang  ², Tingting Bai  ², Jianye Wang  ⁴, Pulin Yu  ⁴, Cuntai Zhang  ⁵, Jinhui Wu  ³, Geriatrics Branch of the Chinese Medical Association; Expert Group of the Chinese Expert Consensus on Assessment of Cognitive Impairment in the Elderly （Affiliations ¹ Department of Geriatrics Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine Shanghai China. ² Department of Geriatrics Ruijin Hospital, Shanghai Jiao Tong University School of Medicine Shanghai China. ³ Center of Gerontology and Geriatrics, National Clinical Research Center for Geriatrics West China Hospital, Sichuan University Chengdu China. ⁴ Beijing Hospital Beijing China. ⁵ Department of Geriatrics, Tongji Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China.）

出处： Aging medicine (Milton (N.S.W)) 2022

关键词： assessment;cognitive impairment;elderly;expert consensus.

摘要： Cognitive impairment is a term that refers to the impairment of one or more cognitive domains to varying degrees caused by a variety of reasons. It is ...

作者： Biao Wang  ¹, Rongzhu Tang  ², Shaohong Wu  ³, Ming Liu  ⁴, Fariha Kanwal  ⁵, Muhammad Fayyaz Ur Rehman  ⁶, Fang Wu  ⁷, Jianping Zhu  ³ （Affiliations ¹ Department of Gastrointestinal Surgery, Renmin Hospital, Hubei University of Medicine, No. 39, Chaoyang Middle Road, Shiyan 442000, China. ² Department of Gastroenterology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, No. 358, Datong Road, Pudong New District, Shanghai 200137, China. ³ Department of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China. ⁴ Department of Emergency, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China. ⁵ Med-X Research Institute, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China. ⁶ Institute of Chemistry, University of Sargodha, Sargodha 40100, Pakistan. ⁷ Department of Gynecology, Obstetrics and Gynae Hospital, Fudan University, Shanghai 200437, China.）

出处： Diagnostics (Basel, Switzerland) 2022

关键词： CD64 index;abdominal infection;acute pancreatitis;neutrophil.

摘要： Objective: To study the clinical diagnostic value of neutrophil CD64 index, PCT, and CRP in patients with acute pancreatitis with abdominal infection. ...

作者： Lu Cheng  ^{1   2}, Jing Hu  ^{1   2}, Ling Zhang  ^{1   2}, Ning Shen  ^{1   2}, Hui Chen  ^{1   2   3   4}, Fang Zhang  ^{1   2   3   4} （Affiliations ¹ National Clinical Research Center for Eye Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. ² Shanghai Key Laboratory of Fundus Diseases, Shanghai 200080, China. ³ Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai 200080, China. ⁴ Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai 200080, China.）

出处： Pharmaceuticals (Basel, Switzerland) 2022

关键词： Lenvatinib;orbital adipose tissue;thyroid eye disease;vascular endothelial growth factor receptor.

摘要： Thyroid eye disease (TED) is the most common orbital disease in adults. Targeting expanded orbital adipose tissue (OAT) removed by surgery has therape ...

作者： Yufan Zheng  ^{1   2}, Wenrui Sun  ², Zhengyang Wang  ³, Jiaying Liu  ², Cong Shan  ¹, Chenxi He  ⁴, Borui Li  ², Xiao Hu  ³, Wenjia Zhu  ², Liyan Liu  ⁵, Fei Lan  ⁴, Changtao Jiang  ⁶, Chao Zhao  ², Xiaobo Li  ², Ning Sun  ^{1   2} （Affiliations ¹ Wuxi School of Medicine, Jiangnan University, Jiangsu, China. ² Department of Physiology and Pathophysiology, State Key Laboratory of Medical Neurobiology, School of Basic Medical Sciences, Fudan University, Shanghai, China. ³ Department of Pathology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China. ⁴ Shanghai Key Laboratory of Medical Epigenetics, International Laboratory of Medical Epigenetics and Metabolism, Ministry of Science and Technology, Institutes of Biomedical Sciences, Fudan University and Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China. ⁵ General Practice/International Medical Care Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁶ Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, China.）

出处： Research (Washington, D.C.) 2022

摘要： Pancreatitis is the leading cause of hospitalization in gastroenterology, and no medications are available for treating this disease in current clinic ...