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作者: Wang, Zi-Haoa;Wang, Jingyib,c;Liu, Fuchend;Sun, Sijunb,e;Zheng, Quanf;Hu, Xiaotiane;Yin, Zihanb,c;Xie, Chengmeib;Wang, Haiyanc;Wang, TianshigCAa;Zhang, ShengjiebCAb;Wang, Yi-Pinga,bCAcaInstitutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, China;bPrecision Research Center for Refractory Diseases, Institute for Clinical Research, Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, China;cDepartment of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, China;dThe Third Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, Third Affiliated Hospital, Naval Medical University, Shanghai, China;eDepartment of Gastrointestinal Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, China;fCenter for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, China;gDepartment of Biochemistry and Molecular Cell Biology, Shanghai Jiao Tong University School of Medicine, China)

出处: FEBS Letters 2024

关键词: histone H3 lysine 4 tri-methylation;liver cancer;mitochondrial respiration;oxidative phosphorylation;SET and MYND domain-containing protein 3;THAP domain-containing 3

摘要: Mitochondria harbor the oxidative phosphorylation (OXPHOS) system to sustain cellular respiration. However, the transcriptional regulation of OXPHOS r ...

作者: Zhou, Zhenga;Hu, Jianhaia;Zhu, Mina;Yu, Jianinga;Liu, Weib;Xu, SudancCAa;Wu, PengbCAbaMedical School, Anhui University of Science and Technology, Anhui, Huainan, China;bDepartment of Orthopedics, Tongji University Tenth People’s Hospital, Shanghai Tenth People’s Hospital, Shanghai, China;cDepartment of Cardiology, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, China)

出处: Medical Science Monitor 2024

关键词: Arthroscopy;Knee;Methylene Blue;Osteoarthritis;Popliteal Cyst

摘要: Background: This retrospective study of 42 patients with popliteal cysts (or Baker cysts) aimed to compare the effects on duration and outcomes of art ...

作者: Zhang, Leia;Sun, Yiwub;Sui, Xina;Zhang, Jiana;Zhao, Jingshuna;Zhou, Runfenga;Xu, Wenjiaa;Yin, Chengkea;He, Zhaoyia;Sun, Yufeia;Liu, Changa;Song, Ailingc;Han, FeiaCAaaDepartment of Anesthesiology, Harbin Medical University Cancer Hospital, Harbin, China;bDepartment of Anesthesiology, Dazhou Central Hospital, Dazhou, China;cDepartment of Anesthesiology, Shanghai Jiao Tong University First People's Hospital (Shanghai General Hospital), Shanghai, China)

出处: ESC Heart Failure 2024

关键词: Acute heart failure;Arterial blood gas;Medical Information Mart for Intensive Care IV;Partial pressure of arterial carbon dioxide

摘要: Aims: Both hypercapnia and hypocapnia are common in patients with acute heart failure (AHF), but the association between partial pressure of arterial ...

作者: Wu, Mingweia;Zeng, Zhaoxiangb;Bao, Xianhaob;Ren, Luxiaa;Feng, Jiaxuanb;Feng, Ruic;Xiong, JiangaCAaaDepartment of Vascular and Endovascular Surgery, Chinese People’s Liberation Army General Hospital, Beijing, China;bDepartment of Vascular Surgery, Changhai Hospital, Navy Medical University, Shanghai, China;cDepartment of Vascular Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China)

出处: Journal of Endovascular Therapy 2024

关键词: blunt thoracic aortic injury;endograft;long-term;multi-center study;thoracic endovascular aneurysm repair

摘要: Objective: This study aimed to assess the long-term outcomes in patients treated by thoracic endovascular aortic repair (TEVAR) for blunt thoracic aor ...

作者: Du, Weia;Li, Yinga;Wang, Xufenga;Xie, Sunzhea;Ci, Hongfeia;Zhou, Jiaminga;Zhu, Ningqia;Chen, Zulea;Zheng, YanbCAa;Jia, Hulianga,cCAbaHepatobiliary Surgery, Department of General Surgery, Huashan Hospital, Fudan University, Shanghai, China;bDepartment of Pancreatic Surgery, Shanghai General Hospital, Shanghai Key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai Jiao Tong University School of Medicine, Shanghai, China;cCancer Metastasis Institute, Fudan University, Shanghai, China)

出处: Cancer Science 2024

关键词: ceRNA;circESYT2;ENO2;hepatocellular carcinoma progression;miR-665

摘要: Circular RNAs (circRNAs) have emerged as crucial regulators in tumor progression, yet their specific role in hepatocellular carcinoma (HCC) remains la ...

作者: Hanqing Liu;Yihui Wang;Qianqian Le;Jiajia Tong;Honglin Wang (Precision Research Center for Refractory Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, P. R. China Shanghai Institute of Immunology, Precision Research Center for Refractory Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China Precision Research Center for Refractory Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China Full correspondence Dr. Honglin Wang, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, China, No. 650 Xin Songjiang Road, Songjiang District, 201620 Shanghai, P. R. China)

出处: European Journal of Immunology 2024

关键词: CD8+ T cells;Cytokine axis;Treatment;Vitiligo

摘要: Vitiligo is a disease featuring distinct white patches that result from melanocyte destruction. The overall pathogenesis of vitiligo remains to be elu ...

作者: Wu, Yuea,b;Liu, Xina,b;Liu, Yuyinga,b;Qian, Wenzhea,b;Huang, Liandia,b;Wu, Yixianga,b;Wang, Xuetonga,b;Yuan, Yinga,b;Ke, Biliana,cCAaaDepartment of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 100 Haining Road, Hongkou District, Shanghai, China;bNational Clinical Research Center for Eye Diseases, Shanghai, China;cDepartment of Ophthalmology, Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China)

出处: Ophthalmology and Therapy 2024

关键词: Anisomyopia;Children;Macular curvature;Microvascularity;Myopia;Optical coherence tomography

摘要: Introduction: To evaluate the intraocular differences in optical coherence tomography (OCT)-based macular curvature index (MCI) among children with an ...

作者: Yan, Weiweia;Xie, Chengmeia;Sun, Sijuna,b;Zheng, Quanc;Wang, Jingyid;Wang, Zihaoe;Man, Cheuk-Himf;Wang, Haiyand;Yang, Yunfang;Wang, Tianshih;Shi, Leileia;Zhang, ShengjieaCAa;Huang, ChenbCAb;Xu, ShuangnianiCAc;Wang, Yi-Pinga,eCAdaPrecision Research Center for Refractory Diseases, Institute for Clinical Research, Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China;bDepartment of Gastrointestinal Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China;cCenter for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China;dDepartment of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China;eInstitutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, 200032, China;fDivision of Haematology, Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong;gDepartment of Cell Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, 250012, China;hDepartment of Biochemistry and Molecular Cell Biology, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China;iDepartment of Hematology, Southwest Hospital, Army Medical University, Chongqing, 400038, China)

出处: EMBO Journal 2024

关键词: FMS-like Tyrosine Kinase 3;Lysine Succinylation;Mitochondrial Biogenesis;Mitochondrial RNA Polymerase;Succinate-CoA Ligase

摘要: Mitochondria are cellular powerhouses that generate energy through the electron transport chain (ETC). The mitochondrial genome (mtDNA) encodes essent ...

作者: Xu, Weiqia;Fei, Xinfenga;Cui, Zeyub;Pan, Dikangc;Liu, YandCAa;Liu, TebCAbaDepartment of Ophthalmology, Shanghai Fourth People’s Hospital, School of Medicine, Tongji University, Shanghai, 200434, China;bShanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Building C, 365 Xiangyang Road, Shanghai, 200031, China;cDepartment of Vascular Surgery, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China;dDepartment of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 100 Haining Road, Shanghai, 200080, China)

出处: Human Cell 2024

关键词: Corneal cryoinjury;DNA methylation;Exosomes;MicroRNA;Murine amniotic fluid mesenchymal stem cells

摘要: Severe corneal cryoinjury can cause permanent corneal swelling and bullous keratopathy, one of the main reason for loss of sight. Mouse amniotic fluid ...

作者: Yang, Xinyua,b;Li, Runhanb;Yang, Xindic;Zhou, Yongd;Liu, Yic;Han, Jing-Dong J.bCAaaSchool of Life Sciences, Peking University, Beijing, 100871, China;bPeking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Center for Quantitative Biology (CQB), Peking University, Beijing, 100871, China;cBeijing Key Lab of Traffic Data Analysis and Mining, School of Computer and Information Technology, Beijing Jiaotong University, Beijing, 100044, China;dClinical Research Institute, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China)

出处: Science China Life Sciences 2024

关键词: age estimation;coordinate-wise monotonic transformation;face point cloud;face verification;privacy

摘要: The human face is a valuable biomarker of aging, but the collection and use of its image raise significant privacy concerns. Here we present an approa ...

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