作者：
Liu, Shiweia,b;Yu, Yanga;Xu, Jiec;Wang, Yia,dCAa;Li, DengaCAb
（aDepartment of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;bDepartment of Urology, Fudan University Shanghai Cancer Center, Shanghai, China;cNursing Department, Wujiang Fifth People's Hospital, Suzhou, China;dDepartment of Urology, Affiliated Hospital of Nantong University, Jiangsu Province, Nantong, China）
摘要：
It was imperative to identify latent biomarkers pertinent to malignancies, given the pivotal role targeted molecular therapies play in tumor treatment
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作者：
Liu, TeaCAa;Wen, Yichaoa;Cui, Zeyua;Chen, Haiyanga;Lin, Jiajiaa;Xu, Jianghongb;Chen, Danpingb;Zhu, Yingb;Yu, Zhihuaa;Wang, ChunxiacCAb;Zhang, BimengdCAc
（aShanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China;bDepartment of Gynaecology, Jingan Hospital of Traditional Chinese Medicine, Shanghai, China;cDepartment of Reproductive Medicine, Henan Province Hospital of Traditional Chinese Medicine, Henan, China;dDepartment of Acupuncture, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China）
出处：
Cell Proliferation 2024
摘要：
The in-depth mechanisms of microRNA regulation of premature ovarian failure (POF) remain unclear. Crispr-cas9 technology was used to construct transge
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作者：
Ma, Jiaqianga;Wu, Yingchenga;Ma, Lifengb;Yang, Xupenga;Zhang, Tianchenga;Song, Guohea;Li, Tengc;Gao, Kea;Shen, Xiaa;Lin, Jiana;Chen, Yaminc;Liu, Xiaoshanc;Fu, Yutingb;Gu, Xixic;Chen, Zechuanc;Jiang, Shanc;Rao, Dongninga;Pan, Jiaomenga;Zhang, Shua;Zhou, Jiana;Huang, Chend;Shi, Sie;Fan, JiaaCAa;Guo, GuojibCAb;Zhang, XiaomingcCAc;Gao, QiangaCAd
（aDepartment of Liver Surgery and Transplantation, Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, 200032, China;bCenter for Stem Cell and Regenerative Medicine, Zhejiang University School of Medicine, Stem Cell Institute, Zhejiang University, Hangzhou, 310058, China;cThe Center for Microbes, Development and Health, Key Laboratory of Immune Response and Immunotherapy, Shanghai Institute of Immunity and Infection, Chinese Academy of Sciences, Shanghai, 200031, China;dDepartment of Gastrointestinal Surgery, Shanghai General Hospital Affiliated to Shanghai Jiaotong University, Shanghai, 200080, China;eDepartment of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai, 200032, China）
出处：
Science 2024
摘要：
B lymphocytes are essential mediators of humoral immunity and play multiple roles in human cancer. To decode the functions of tumor-infiltrating B cel
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作者：
Zhao, Yucuia,b;He, Sijiaa;Zhao, Minghuia,c;Huang, Qiana,dCAa
（aCancer Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China;bDepartment of Radiation Oncology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, China;cDepartment of Radiation Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China;dShanghai Key Laboratory of Pancreatic Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China）
出处：
Advanced Science 2024
关键词：
cancer resistance;cytotoxic therapy;depolyploidization;polyaneuploid giant cancer cells;polyploidization
摘要：
Polyploidization and depolyploidization are critical processes in the normal development and tissue homeostasis of diploid organisms. Recent investiga
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作者：
Li, JingjieaCAa;Qin, Zuoshua;Li, Yunqib;Huang, Baozhua;Xiao, Qimenga;Chen, Peiqina;Luo, Yifana;Zheng, Wenxinc,d,e;Zhang, TaofCAb;Zhang, Zhenboa,gCAc
（aPrecision Research Center for Refractory Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China;bShanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China;cDepartment of Pathology, University of Texas Southwestern Medical Center, Dallas, 75390, TX, United States;dDepartment of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, 75390, TX, United States;eSimon Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, 75390, TX, United States;fDepartment of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China;gReproductive Medicine Center, Department of Obstetrics and Gynecology, Tongji hospital, School of Medicine, Tongji University, Shanghai, 200065, China）
摘要：
The progestin regimen is one of the main therapeutic strategies for women with endometrial cancer who undergo conservative management. Although many p
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作者：
Liu, Kaiyuana;Zan, Pengfeia;Li, Zihuab;Lu, Henglib;Liu, Pengc;Zhang, Lib;Wang, Hongshenga;Ma, Xiaojuna;Chen, FengdCAa;Zhao, JingcCAb;Sun, WeiaCAc
（aDepartment of Bone Tumor Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China;bSchool of Medicine, Tongji University, Shanghai, 200072, China;cScientific Research Center, The Seventh Affiliated Hospital of Sun Yat-Sen University, No. 628 Zhenyuan Road, Guangdong, Shenzhen, 518107, China;dShanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Stomatological Hospital and School of Stomatology, Fudan University, Shanghai, 200001, China）
摘要：
The immunosuppressive tumor microenvironment (ITME) of osteosarcoma (OS) poses a significant obstacle to the efficacy of existing immunotherapies. Des
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作者：
Dong, Lingkaia;Liu, Minchaoa;Fang, Mengb;Lu, Qianqiana;Li, Xingjina;Ma, Yanminga;Zhao, TiancongaCAa
（aSchool of Chemistry and Materials, Department of Chemistry, Laboratory of Advanced Materials and Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, State Key Laboratory of Molecular Engineering of Polymers, Collaborative Innovation Center of Chemistry for Energy Materials (2011-iChEM), Fudan University, Shanghai, 200433, China;bDepartment of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China）
摘要：
Albeit microemulsion systems have emerged as efficient platforms for fabricating tunable nano/microstructures, lack of understanding on the emulsion-i
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作者：
Song, Jiahuia;Dong, Jizeb;Yuan, Zhengchaoa;Huang, Moranb;Yu, Xiaoa;Zhao, Yuea;Shen, Yihonga;Wu, Jingleia;EL-Newehy, Mohamedc;Abdulhameed, Meera Moydeenc;Sun, BinbinaCAa;Chen, JiwubCAb;Mo, XiumeiaCAc
（aState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai, 201620, China;bDepartment of Sports Medicine, Shanghai General Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, 200080, China;cDepartment of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451, Saudi Arabia）
摘要：
To solve the problems of slow regeneration and mismatch of axon regeneration after peripheral nerve injury, nerve guidance conduits (NGCs) have been w
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作者：
Gu, Junhaoa;Cheng, Danlinga;Li, Haiyanb;Yu, Taoa;Zhang, Zhenghea;Liu, Yuea;Wang, XiaoyingcCAa;Lu, XiabCAb;Li, JingchaoaCAc
（aState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai, 201620, China;bDepartment of Nuclear Medicine, Northern Jiangsu People's Hospital, Clinical Medical College, Yangzhou University, Yangzhou, 225001, China;cOffice of Hospital Infection and Disease Control and Prevention, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China）
出处：
Journal of Materials Chemistry B 2024
摘要：
Due to the rapid progression and aggressive metastasis of breast cancer, its diagnosis and treatment remain a great challenge. The simultaneous inhibi
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作者：
Ou, Ningjinga,b,c;Wang, Yucic;Xu, Shuaia;Luo, Jiaqianga;Zhang, Chenwanga;Zhang, Yangyic;Shi, Xiaoyanc;Xiong, Minggangc;Zhao, Liangyub;Ji, Zhiyonga;Zhang, Yuxianga;Zhao, Jingpenga;Bai, Haoweia;Tian, Ruhuia;Li, Penga;Zhi, Erleia;Huang, Yuhuaa;Chen, Weia;Wang, Ruiqic;Jin, Yuxuanc;Wang, Dianc;Li, ZhengaCAa;Chen, HaocCAb;Yao, ChenchengaCAc
（aDepartment of Andrology, Center for Men's Health, Urologic Medical Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China;bDepartment of Urology, Department of Interventional Medicine, Guangdong Provincial Key Laboratory of Biomedical Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Guangdong, Zhuhai, 519000, China;cDepartment of Human Cell Biology and Genetics, Joint Laboratory of Guangdong & Hong Kong Universities for Vascular Homeostasis and Diseases, School of Medicine, Southern University of Science and Technology, Guangdong, Shenzhen, 518000, China）
出处：
Advanced Science 2024
关键词：
DAZ;microdeletion of AZFc;proliferation;RNA binding protein;spermatogenic failure
摘要：
Primate-specific DAZ (deleted in azoospermia) has evolved in the azoospermia factor c (AZFc) locus on the Y chromosome. Loss of DAZ is associated with
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