作者： Min Yan^{1 na1};Lu Cheng^{2,3 na1};Zheng Zheng^2,3;Yuanxi Lin⁴;Doudou Qin⁴ & …Hui Chen^1,2,3,4 （¹Eye School of Chengdu, University of Traditional Chinese Medicine, Chengdu, Sichuan, China;²Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;³National Clinical Research Center for Eye Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;⁴University of Shanghai for Science and Technology, Shanghai, China）

出处： BMC Immunology 2025

关键词： Ocular lymphatics;Nasal lymphatics;Cerebrospinal fluid;Lymphatic system;Lymphatic vessels

摘要： Recent research advancements have enhanced our understanding of the lymphatic system in the eye and nasal region and its involvement in health and dis ...

作者： Zeng Zhou  ¹, Tiewen Li  ¹, Yichen Zhang  ¹, Xuehao Zhou  ¹, Xiaodong Song  ¹, Shiyu Ji  ¹, Yishu Huang  ², Yu Zhang  ¹, Yuan Ruan  ¹ （Affiliations ¹ Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of General Surgery, Pancreatic Disease Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： APL bioengineering 2025

摘要： Immunotherapy resistance is a significant obstacle in the treatment of prostate cancer (PCa), primarily due to immune evasion mechanisms. This study a ...

作者： Han Liu ^{#  1}, Mingming Jiang ^{#  1}, Jiaying Wu ^{#  2}, Yue Dai  ¹, Minyi Xu  ¹, Lei Wang  ³, Muyuan Ji  ⁴ （Affiliations ¹ Department of Clinical Laboratory, Shanghai Eighth People's Hospital, Shanghai, 200235, China. ² Department of Laboratory Medicine, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201800, China. ³ Department of Clinical Laboratory, Shanghai Eighth People's Hospital, Shanghai, 200235, China. wolei6610@126.com. ⁴ Department of Hematology and Oncology, Children's Hospital Affiliated to Shandong University, Jinan, China. jimuyuan@126.com.）

出处： Virology journal 2025

关键词： Age;Female;Genetic typing;Human papillomavirus;Infection rate.

摘要： Objective: In China, Cervical cancer is one of the common malignant tumors in females, and high-risk human papillomavirus (HR-HPV) infection is one of ...

作者： Yingchi Shan¹;Yajun Xue¹;Jun Zhu⁴;Thijs Vande Vyvere^5,6;Dana Pisică^7,8;Andrew Maas^9,10;Shuo Zhang^{2,3 na1} & …Guoyi Gao^{2,3 na1} （¹Department of Neurosurgery, School of Medicine, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China;²Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China;³Key Laboratory of Central Nervous System Injury, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China;⁴Department of Neurosurgery, Zhongda Hospital, Southeast University, Nanjing, China;⁵Department of Radiology, Antwerp University Hospital, Antwerp, Belgium;⁶Department of Molecular Imaging and Radiology (MIRA), Faculty of Medicine and Health Science, University of Antwerp, Antwerp, Belgium;⁷Department of Neurosurgery, Erasmus MC—University Medical Center Rotterdam, Rotterdam, The Netherlands;⁸Department of Public Health, Erasmus MC—University Medical Center Rotterdam, Rotterdam, The Netherlands;⁹Department of Neurosurgery, Antwerp University Hospital, Edegem, Belgium;¹⁰University of Antwerp, Edegem, Belgium）

出处： Critical Care 2025

关键词： Traumatic brain injury;Radiomic features;Intracranial hypertension;Prediction

摘要： Background Head computed tomography (CT) is a routinely performed examination to assess the intracranial condition of patients with traumatic brain i ...

作者： Manjing Cao  ^{1   2}, Yahan Zhang  ^{1   2}, Yan Li  ³, Xian Zhang  ⁴, Mingming Ma  ^{1   2} （Affiliations ¹ Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China. ³ Precision Research Center for Refractory Disease, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁴ Department of Ophthalmology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.）

出处： Investigative ophthalmology & visual science 2025

摘要： Purpose: Photoreceptor (PR) death is the ultimate cause of irreversible vision loss in retinal detachment (RD). Previous studies have shown that micro ...

作者： Jun Dong  ^{1   2}, Runjianya Ling  ³, Zhenxing Huang  ¹, Yidan Xu  ⁴, Haiyan Wang  ¹, Zixiang Chen  ¹, Meiyong Huang  ¹, Vladimir Stankovic  ², Jiayin Zhang  ⁴, Zhanli Hu  ¹ （Affiliations ¹ Lauterbur Research Center for Biomedical Imaging, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China. ² Department of Electronic and Electrical Engineering, University of Strathclyde, Glasgow G1 1XQ, UK. ³ Institute of Diagnostic and Interventional Radiology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China. ⁴ Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.）

出处： Journal of X-ray science and technology 2025

关键词： X-ray computed;deep learning;myocardial ischemia;perfusion imaging;tomography.

摘要： Background:: Myocardial blood flow (MBF) provides important diagnostic information for myocardial ischemia. However, dynamic computed tomography perfu ...

作者： Yuhe Liu  ¹, Liang Zhang  ², Yuehao Xu  ³, Tianyun Zhou  ⁴, Wenqian Wu  ¹, Kangnan Zhang  ¹, Rongdi Xu  ¹, Wangyang Chen  ⁵, Weifang Xu  ⁶, Yong Zhou  ¹, Xingdong Zheng  ¹, Baofu Chen  ² （Affiliations ¹ Clinical Research Institute, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of Cardiothoracic Surgery, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, China. ³ Department of Pediatrics, The Third People's Hospital of Longgang District, Shenzhen, China. ⁴ Clinical Medicine, School of Basic Medicine, Shanghai Medical College Fudan University, Shanghai, China. ⁵ School of Medicine, Taizhou University, Taizhou, China. ⁶ Department of Orthopedics, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, China.）

出处： Diabetes, obesity & metabolism 2025

关键词： lipoprotein‐associated phospholipase A2;prospective study;remnant cholesterol.

摘要： Aims: To explore the association of remnant cholesterol (RC) and lipoprotein-associated phospholipase A2 (Lp-PLA2) with composite adverse events in a ...

作者： Hao-Wei Bai  ¹, Na Li  ¹, Yu-Xiang Zhang  ¹, Jia-Qiang Luo  ¹, Ru-Hui Tian  ¹, Peng Li  ¹, Yu-Hua Huang  ¹, Fu-Rong Bai  ¹, Cun-Zhong Deng  ¹, Fu-Jun Zhao  ¹, Ren Mo  ², Ning Chi  ², Yu-Chuan Zhou  ^{3   4}, Zheng Li  ¹, Chen-Cheng Yao  ¹, Er-Lei Zhi  ¹ （Affiliations ¹ Department of Andrology, The Center for Men's Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200000, China. ² Department of Urology, Inner Mongolia People's Hospital, Inner Mongolia Urological Institute, Hohhot 010017, China. ³ International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200000, China. ⁴ Shanghai Key Laboratory of Embryo Original Diseases, Shanghai 200000, China.）

出处： Asian journal of andrology 2025

摘要： Nonobstructive azoospermia (NOA), one of the most severe types of male infertility, etiology often remains unclear in most cases. Therefore, this stud ...

作者： Mingkui Shen  ¹, Yan Hou  ², Shihui Xu  ², Jun Tan  ¹, Honggang Zhou  ¹, Qi Miao  ³, Wanheng Zhang  ³, Yazhou Chen  ^{4   5}, Nana Wang  ⁶, Yongtao Wang  ⁷ （Affiliations ¹ Department of Mini-Invasive Spinal Surgery, The Third People's Hospital of Henan Province, Zhengzhou, 450000, China. ² School of Medicine, Shanghai University, Shanghai, 200444, China. ³ Department of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China. ⁴ Medical 3D Printing Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, 450052, China. yzchenbio@zzu.edu.cn. ⁵ Henan Institute of Advanced Technology, Zhengzhou University, Zhengzhou, 450003, China. yzchenbio@zzu.edu.cn. ⁶ Department of Pediatrics, School of Medicine, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 200080, China. wang-nana@sjtu.edu.cn. ⁷ School of Medicine, Shanghai University, Shanghai, 200444, China. yongtao_wang@shu.edu.cn.）

出处： Journal of nanobiotechnology 2025

关键词： Cytoskeletal nanomechanics;Gene delivery and expression;Intelligent microarray biochips;Mechanotransduction;Patterned stem cells.

摘要： Biochips are widely applied to manipulate the geometrical morphology of stem cells in recent years. Patterned antenna-like pseudopodia are also probed ...

作者： Hui-Ying Zhang ^{#  1   2}, Qiu-Yang Zhang ^{#  1   2}, Qing Liu ^{#  1   2}, Si-Guo Feng  ^{1   2}, Yan Ma  ^{1   2}, Feng-Sheng Wang  ^{1   2}, Yue Zhu  ^{1   2}, Jin Yao  ^{3   4}, Biao Yan  ⁵ （Affiliations ¹ The Affiliated Eye Hospital, Nanjing Medical University, Nanjing, 210000, China. ² The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, 210000, China. ³ The Affiliated Eye Hospital, Nanjing Medical University, Nanjing, 210000, China. dryaojin@126.com. ⁴ The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, 210000, China. dryaojin@126.com. ⁵ Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200080, China. biao.yan@shgh.cn.）

出处： Journal of nanobiotechnology 2025

关键词： ANGPT2;Exosomes;Ocular neovascularization;VEGFA;miR-205.

摘要： Pathological neovascularization is a hallmark of many vision-threatening diseases. However, some patients exhibit poor responses to current anti-VEGF ...