作者： Junying Wei  ¹, Heshan Cao  ², Mingling Peng  ¹, Yinzhou Zhang  ³, Sibei Li  ⁴, Wuhua Ma  ⁵, Yuhui Li  ⁵ （Affiliations ¹ First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China. ² Department of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China. ³ Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China. ⁴ Department of Anesthesiology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China. ⁵ Department of Anesthesiology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.）

出处： PloS one 2025

摘要： Background: Ventilator-associated pneumonia (VAP) is a common nosocomial infection in ICU, significantly associated with poor outcomes. However, there ...

作者： Ruqiang Yuan ^{#  1}, Mingjing Gao ^{#  2   3}, Hu Xu ^{#  4}, Qing Liang  ¹, Lei Qian  ¹, Yali Wang  ¹, Houli Zhang  ⁵, Erjiao Qiang  ⁶, Weijing Yun  ⁷ （Affiliations ¹ Advanced Institute for Medical Sciences, Dalian Medical University, Dalian, 116044, China. ² Department of Pharmacy, Dalian Port Hospital, Dalian, 116001, China. ³ College of Pharmacy, Dalian Medical University, Dalian, 116044, China. ⁴ Wuhu Hospital and Health Science Center, East China Normal University, Shanghai, 200241, China. ⁵ College of Pharmacy, Dalian Medical University, Dalian, 116044, China. houlizh@163.com. ⁶ Department of Pathology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, China. qiangerjiao@126.com. ⁷ Advanced Institute for Medical Sciences, Dalian Medical University, Dalian, 116044, China. yunweijing@dmu.edu.cn.）

出处： BMC cardiovascular disorders 2025

关键词： Calcium influx;Alantolactone;Hypertension;Voltage-gated Calcium Channels.

摘要： Background: The dried root of Inula helenium L., known as Inulae Radix in Mongolian medicine, is a widely used heat-clearing plant drug within the Ast ...

作者： Ying Zhang ^{#  1   2   3}, Yan Ma ^{#  1   2}, Yu-Ke Ji ^{#  1   2}, Yi-Fei Jiang  ^{1   2}, Duo Li  ^{1   2}, Wan Mu  ⁴, Mu-Di Yao  ⁵, Jin Yao  ^{6   7}, Biao Yan  ⁸ （Affiliations ¹ The Affiliated Eye Hospital, Nanjing Medical University, Nanjing, 210000, China. ² The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, 210000, China. ³ Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200080, China. ⁴ Eye Institute, Department of Ophthalmology, Eye and ENT Hospital, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, 200030, China. ⁵ Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200080, China. mudiyao@163.com. ⁶ The Affiliated Eye Hospital, Nanjing Medical University, Nanjing, 210000, China. jinyao1972@126.com. ⁷ The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, 210000, China. jinyao1972@126.com. ⁸ Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200080, China. yanbiao@sjtu.edu.cn.）

出处： Cell communication and signaling : CCS 2025

关键词： Ischemic/reperfusion injury;Müller cells;Reactive gliosis;Retinal ganglion cells;tsRNA.

摘要： Ischemic retinopathies are the major causes of blindness, yet effective early-stage treatments remain limited due to an incomplete understanding of th ...

作者： Jiandong Zhou  ¹, Yunshan Guo  ¹, Xuan Liu  ¹, Weijie Yuan  ¹ （Affiliation ¹ Department of Nephrology, Shanghai General Hospital of Nanjing Medical University, Shanghai, China.）

出处： Adipocyte 2025

关键词： Secretory proteins;adipose tissue;bioinformatics;epigenetics;metabolic syndrome.

摘要： The objective of this study was to identify key secretory protein-encoding differentially expressed genes (SP-DEGs) in adipose tissue in female metabo ...

作者： Wei Chen  ¹, Yuanjun Tang  ², Yachen Si  ¹, Boxiang Tu  ³, Fuchuan Xiao  ⁴, Xiaolu Bian  ¹, Ying Xu  ¹, Yingyi Qin  ³ （Affiliations ¹ Department of Nephrology, Shanghai Changhai Hospital, Shanghai 200433, China. ² Department of Clinical Pharmacy, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200240, China. ³ Department of Military Health Statistics, Naval Medical University, Shanghai 200433, China. ⁴ Navy No. 929 Hospital, Shanghai 200433, China.）

出处： Journal of translational internal medicine 2025

关键词： all-cause mortality;chronic kidney disease;life’s essential 8.

摘要： Background and objectives: The association between chronic kidney disease (CKD) and cardiovascular disease has been previously evaluated. This study a ...

作者： Liang Wang  ¹, Yuanqi Wang  ², Tiantian Jiao  ², Linghao Xu  ¹, Endong Ji  ³, Sakibur Rahman Tapu  ², Yehong Liu  ¹, Jiming Li  ^{4   5} （Affiliations ¹ Department of Cardiology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China. ² School of Medicine, Tongji University, Shanghai, China. ³ Department of Emergency and Critical Care, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁴ Department of Cardiology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China. ljm13303818674@126.com. ⁵ Department of Cardiology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, 200092, China. ljm13303818674@126.com.）

出处： Journal of cardiothoracic surgery 2025

关键词： Arterial stiffness;Continuous positive airway pressure;Coronary heart disease;Inflammatory factors;Obstructive sleep apnea.

摘要： Background: Continuous Positive Airway Pressure (CPAP) treatment brings more benefits than risks to most coronary heart disease (CHD) patients with ob ...

作者： Hui Cheng  ¹, Li Chen  ¹, Chongmei Huang  ² （Affiliations ¹ Department of Hematology, First Affiliated Hospital, Naval Medical University, Shanghai 200433, P.R. China. ² Department of Hematology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, P.R. China.）

出处： Oncology letters 2025

关键词： acute myeloid leukemia;function;inhibitors;signal transducer and activator of transcription 3;targeted therapy.

摘要： Signal transducer and activator of transcription 3 (STAT3), a crucial transcription factor, exerts a notable influence by hyperactivating or acquiring ...

作者： Ruilong Wang  ¹, Yue Yin  ², Yongxing Zhang  ³, Yi Liu  ⁴, Xinyu Wang  ⁵, Chencong Lv  ⁵, Xiao Bin  ⁴, Yanhai Xi  ⁴, Weiheng Wang  ⁴, Guoying Deng  ⁶, Songkai Li  ⁷, Chengwei Yang  ⁷ （Affiliations ¹ Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China. ² Department of Laboratory Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P.R.China. ³ Department of Orthopedics, Second Affiliated Hospital of Zhejiang University, Hangzhou, P.R.China. ⁴ Department of Orthopaedics, Second Affiliated Hospital of Naval Medical University, Shanghai, P.R.China. ⁵ Shanghai Jiaotong University School of Medicine, Shanghai, P.R.China. ⁶ Trauma Center, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, P.R.China. ⁷ Department of Spine Surgery, The 940th Hospital of Joint Logistics Support Force of PLA, Lanzhou, Gansu, P.R. China.）

出处： International journal of environmental health research 2025

关键词： Neck and shoulder pain;college students;spinal curvature;use of digital products.

摘要： Neck and shoulder pain (NSP) is a common issue among college students, yet no studies have linked digital device usage to NSP prevalence in China. Thi ...

作者： Yi Lu  ¹, Jiamin Xie  ¹, Lele Cheng  ², Qingdong Fu  ², Miao Wu  ³, Ji Jin  ⁴, Xun Xu  ⁵ （Affiliations ¹ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Clinical Research Center for Eye Diseases, Shanghai, China; Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai, China; Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China; Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China, Shanghai, China. ² Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China, Shanghai, China. ³ Hangzhou Chaoju Eye Hospital, Hangzhou, Zhejiang Province, China. ⁴ Hangzhou Chaoju Eye Hospital, Hangzhou, Zhejiang Province, China. Electronic address: jinji2@sina.com.cn. ⁵ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Clinical Research Center for Eye Diseases, Shanghai, China; Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai, China; Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China; Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China, Shanghai, China. Electronic address: drxuxun@sjtu.edu.cn.）

出处： Asia-Pacific journal of ophthalmology (Philadelphia, Pa.) 2025

关键词： axial length;myopia control;myopia progression;recombinant human growth hormone.

摘要： Purpose: To explore the correlation between recombinant human growth hormone (rhGH) therapy and myopia progression, and to optimize the myopia control ...

作者： Zhi-Hao Du  ¹, Wei-Xia Chu  ^{2   3}, Xin Peng  ¹, Li-Ling Wu  ⁴, Yan Liu  ², Guang-Yan Yu  ¹, Chong Ding  ² （Affiliations ¹ Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology & NHC Key Laboratory of Digital Stomatology & NMPA Key Laboratory for Dental Materials, No. 22, Zhongguancun South Avenue, Haidian District, Beijing 100081, P. R. China. ² Center Laboratory, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology & NHC Key Laboratory of Digital Stomatology & NMPA Key Laboratory for Dental Materials, No. 22, Zhongguancun South Avenue, Haidian District, Beijing 100081, P. R. China. ³ Shanghai General Hospital, Shanghai 200080, P. R. China. ⁴ Department of Physiology and Pathophysiology, Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, and Beijing Key Laboratory of Cardiovascular Receptors Research, Peking University School of Basic Medical Sciences, Beijing 100191, P. R. China.）

出处： ACS applied materials & interfaces 2025

关键词： Sjögren’s syndrome;T-bet;Th1 cell;exosomes;miR-29a-3p;saliva.

摘要： Background: Sjögren's syndrome (SS), an autoimmune disease, was characterized by sicca syndrome and systemic manifestations, presenting significant tr ...