作者： Cai Zhang  ¹, Xuejiao Song  ¹, Chuan Ma  ², Minjia Wang  ¹, Hui Deng  ³, Miaomiao Yuan  ⁴, Wuyou Zhu  ⁵, Lingyue Shen  ⁶, Yuzhen Li  ⁷, Leilei Shi  ⁸ （Affiliations ¹ The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, China. ² Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University, China. ³ Department of Dermatology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: hdeng@sjtu.edu.cn. ⁴ Shanghai Key Laboratory of Pancreatic Diseases, Precision Research Center for Refractory Diseases in Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁵ Shanghai Foreign Language School Affiliated to Shanghai International Studies University, Shanghai, China. ⁶ Department of Oral & Maxillofacial-Head & Neck Oncology, Department of Laser and Aesthetic Medicine, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: sharyshen@hotmail.com. ⁷ The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, China. Electronic address: liyzh56@mail.sysu.edu.cn. ⁸ Shanghai Key Laboratory of Pancreatic Diseases, Precision Research Center for Refractory Diseases in Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: leilei.shi@shgh.cn.）

出处： International journal of biological macromolecules 2024

关键词： Dissolving microneedle;Hyaluronic acid;Melanin;Melasma;Tranexamic acid.

摘要： Melasma is an acquired hypermelanotic condition characterized by the presence of irregular light-to-dark brown macules that primarily manifest on the ...

作者： Jun Hou  ^{1   2   3}, Hui Du  ^{1   2   3}, Chun Wang  ^{1   2   3}, Fangbin Song  ⁴, Xinfeng Qu  ⁵, Ruifang Wu  ^{1   2   3} （Affiliations ¹ Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen, China. ² Institute of Obstetrics and Gynecology, Shenzhen Peking University-Hongkong University of Science and Technology (PKU-HKUST) Medical Center, Shenzhen, China. ³ Shenzhen Key Laboratory on Technology for Early Diagnosis of Major Gynecologic Diseases, Peking University Shenzhen Hospital, Shenzhen, China. ⁴ Department of General Surgery, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China. ⁵ Department of Obstetrics and Gynecology, Sanming Project of Medicine in Peking University Shenzhen Hospital, Shenzhen, Guangdong, China.）

出处： Frontiers in oncology 2024

关键词： P16 immunocytochemical stain;atrophy;cytology;high-grade squamous intraepithelial lesion (HSIL);menopause.

摘要： Background: Few articles have focused on the cytological misinterpretation of high-grade squamous intraepithelial lesion (HSIL). Due to estrogen defic ...

作者： Da Lu  ^{1   2}, Jiajia Fan  ³, Yang Lin  ⁴, Kai Yang  ⁵, Fuzhen Zheng  ⁶, Teng Ma  ², Feng Zhu  ² （Affiliations ¹ Department of Thoracic-Cardiac Surgery, Hubei Provincial Hospital of Traditional Chinese Medicine, Affiliated Hospital of Hubei University of Chinese Medicine, Wuhan. ² Department of Vascular Surgery, General Surgery Clinical Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai. ³ Community Health Service Center of Caoyang Street, Putuo District, Shanghai. ⁴ Department of Cardiovascular Surgery, Gaozhou Hospital, Gaozhou. ⁵ Community Health Service Center of Zhoujiaqiao Street, Changning District, Shanghai. ⁶ Department of Cardiovascular Surgery, Shengli Clinical Medical College of Fujian Medical University, Fujian Medical University, Fuzhou, People's Republic of China.）

出处： Annals of medicine and surgery (2012) 2024

关键词： IL-4;macrophage polarization;myocardial infarction.

摘要： IL-4, an immunoregulatory cytokine, plays a role in various cellular pathways and is known to regulate M2 macrophage polarization. Numerous studies ha ...

作者： Bin Zhang  ^{1   2}, Rui Yang  ^{2   3}, Hongwei Yu  ⁴, Yamin Peng  ², Haoyu Huang  ², Meera Moydeen Abdul Hameed  ⁵, Han Wang  ⁴, Guixiang Zhang  ¹, Mohamed El-Newehy  ⁵, Mingwu Shen  ², Xiangyang Shi  ^{2   6}, Shaojun Peng  ⁷ （Affiliations ¹ Department of Radiology, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, Shanghai 200434, China. Guixiangzhang@sina.com. ² State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai 201620, China. xshi@dhu.edu.cn. ³ Medical School, Kunming University of Science and Technology, Kunming 650500, China. ⁴ Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. ⁵ Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia. ⁶ CQM-Centro de Quimica da Madeira, Universidade da Madeira, Funchal 9020-105, Portugal. ⁷ Center for Biological Science and Technology & College of Arts and Sciences, Beijing Normal University, Zhuhai 519087, China. 91122024006@bnu.edu.cn.）

出处： Biomaterials science 2024

摘要： Developing effective nanomedicines to cross the blood-brain barrier (BBB) for efficient glioma theranostics is still considered to be a challenging ta ...

作者： Kangkang Ou  ¹, Yang Liu  ², Lili Deng  ³, Shiyan Chen  ⁴, Song Gu  ⁵, Baoxiu Wang  ⁶ （Affiliations ¹ School of Textiles and Fashion, Shanghai University of Engineering Science, Shanghai 201620, PR China; State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, PR China. ² School of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai 201620, PR China. ³ State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, PR China. ⁴ State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, PR China. Electronic address: chensy@dhu.edu.cn. ⁵ Trauma Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, PR China. Electronic address: song.gu@shgh.cn. ⁶ School of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai 201620, PR China. Electronic address: baoxiu.wang@mail.dhu.edu.cn.）

出处： International journal of biological macromolecules 2024

关键词： Anti-cell adhesion;Antibacterial activity;Bacterial cellulose;Wound dressing.

摘要： Hydrogel-based wound dressings are becoming increasingly important for wound healing. Bacterial cellulose (BC) has been commonly used as wound dressin ...

作者： Shuoer Wang  ¹, Lun Xu  ², Dongliang Wang  ³, Songjiao Zhao  ⁴, Kun Li  ², Fen Ma  ⁵, Qianlan Yao  ⁶, Yunkui Zhang  ⁷, Zhiqiang Wu  ², Yang Shao  ⁸, Shaoli Song  ⁹, Wangjun Yan  ¹⁰ （Affiliations ¹ Department of Musculoskeletal Oncology, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Nuclear Medicine, Cancer Institute, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. ² Department of Musculoskeletal Oncology, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. ³ Department of Nuclear Medicine, Cancer Institute, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. ⁴ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁵ Shanghai Key Laboratory of Compound Chinese Medicines, The MOE Key Laboratory for Standardization of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China. ⁶ Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. ⁷ Department of Anesthesiology, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. ⁸ Cancer Institute, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address: thierryhenrysy@gmail.com. ⁹ Department of Nuclear Medicine, Cancer Institute, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address: shaoli-song@163.com. ¹⁰ Department of Musculoskeletal Oncology, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address: yanwj@fudan.edu.cn.）

出处： Cancer letters 2024

关键词： Bone metastatic breast cancer;EZH2;Osteolytic destruction;YTHDF1;m6A.

摘要： Bone metastasis is common in breast cancer and more effective therapies are required, however, its molecular mechanism is poorly understood. Additiona ...

作者： Zheng-Li Xu  ¹, Lan-Ping Xu  ¹, Yi-Cheng Zhang  ², Yu-Hong Zhou  ³, Er-Lie Jiang  ⁴, Jian-Ping Zhang  ⁵, Bin Fu  ⁶, Gui-Fang Ouyang  ⁷, Xian-Min Song  ⁸, Xue-Jun Zhang  ⁹, Yu-Jun Dong  ¹⁰, Nai-Nong Li  ¹¹, Ling Wang  ¹², Xi Zhang  ¹³, Peng-Cheng He  ¹⁴, Fan-Sheng Kong  ¹⁵, Hui-Xia Liu  ¹⁶, Li Liu  ¹⁷, Lin Liu  ¹⁸, Tai-Wu Xiao  ¹⁹, Wen-Wei Xu  ²⁰, Xiao-Jun Xu  ²¹, Guo-Lin Yuan  ²², Hai Yi  ²³, Dan Yu  ²⁴, Li Yu  ²⁵, Xiao-Jun Huang  ²⁶ （Affiliations ¹ Peking University People's Hospital, Peking University Institute of Hematology, Beijing, China; National Clinical Research Center for Hematologic Disease, Beijing. ² Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Key Laboratory of Organ Transplantation, Ministry of Education; NHC Key Laboratory of Organ Transplantation; Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan, China; Immunotherapy Research Center for Hematologic Diseases of Hubei Province, Wuhan, Hubei. ³ Department of Hematology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, Zhejiang. ⁴ State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China; Tianjin Institutes of Health Science, Tianjin. ⁵ Hebei Yanda Lu Daopei Hospital, Langfang, Hebei. ⁶ Department of Hematology, Xiangya Hospital of Central South University, National Clinical Research Center for Geriatric Diseases, Changsha, Hunan. ⁷ Department of Hematology, the First Affiliated Hospital of Ningbo University. Ningbo, Zhejiang. ⁸ Department of Hematolgy, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai. ⁹ Department of Hematology, The Second Hospital of Hebei Medical University, Hebei Key Laboratory of Hematology, Shijiazhuang, Hebei. ¹⁰ Department of Hematology, Peking University First Hospital, Beijing. ¹¹ Department of Hematology, Hematopoietic Stem Cell Transplantation Center, Fujian Institute of Hematology, Fujian Provincial Key Laboratory on Hematology, Fujian Medical University Union Hospital, Translational Medicine Center on Hematology of Fujian Medical University, Fuzhou, Fujian. ¹² Department of Hematology, Affiliated Qingdao Central Hospital of Qingdao University, Qingdao, Shandong. ¹³ Medical Center of Hematology, Xinqiao Hospital, State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University. Chongqing. ¹⁴ Department of Hematology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an. ¹⁵ The Affliated Hospital of Shandong University of TcM, Jinan, Shandong. ¹⁶ Department of Hematology, Shanghai Zhaxin Integrated Traditional Chinese and Western Medicine Hospital, Shanghai. ¹⁷ Department of Hematology, Tangdu hospital, The air force medical University, Xi'an. ¹⁸ Department of Hematology, The first affiliated hospital of chongqing medical university. Chongqing. ¹⁹ Department of Hematology, Liaocheng People's Hospital, Liaocheng, Shandong. ²⁰ Department of Hematology, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Jinan, Shandong. ²¹ Department of Hematology, The Seventh Affiliated Hospital, Sun Yet-sen University, Shenzhen, Guangdong. ²² Department of Haematology, Xiangyang Central Hospital, The Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, Hubei. ²³ Department of Hematology, The General Hospital of Western Theater Command, Chengdu, Sichuan. ²⁴ Department of Hematology, Wuhan No.1 Hospital, Wuhan, Hubei. ²⁵ Department of Hematology, the Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi. ²⁶ Peking University People's Hospital, Peking University Institute of Hematology, Beijing, China; National Clinical Research Center for Hematologic Disease, Beijing, China; Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China; Peking-Tsinghua Center for Life Sciences, Beijing. xjhrm@medmail.com.cn.）

出处： Haematologica 2024

作者： Chenyang Jin¹;Zikan Zhong¹;Longzhe Gao¹;Xiaoyu Wu¹;Changzuan Zhou¹;Genqing Zhou¹;Shaowen Liu¹ （¹Department of Cardiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 201620 Shanghai, China）

出处： Reviews in Cardiovascular Medicine 2024

关键词： atrial fibrillation;ferroptosis;inflammation

摘要： In this comprehensive review, we examine the intricate interplay between inflammation, ferroptosis, and atrial fibrillation (AF), highlighting their s ...

作者： JIN Bu¹;CHEN Hanzhang²;XU Hudong¹;CHEN Wanyu¹;YUAN Ying¹;ZHAO Tingting¹;HUANG Xiaolei¹;HE Jialu¹;YU Hong¹ （¹Department of Pathology, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201803, China;²Department of Pathology, Zhabei Central Hospital of Shanghai Jingan District, Shanghai 200070, China）

出处： Shanghai Jiaotong Daxue xuebao. Yixue ban 2024

关键词： hypertrophic cardiomyopathy (hcm);trimethylamine oxide (tmao);protein kinase a (pka);ryanodine receptor 2 (ryr2)

摘要： Objective·To investigate the effects of trimethylamine oxide (TMAO) on cardiac function in mice with hypertrophic cardiomyopathy (HCM) and its potenti ...

作者： Zhiwen Deng ^{#  1   2}, Liangyu Zhao ^{#  1   3   4}, Sha Li ^{#  1   2}, Xiaoyang Chen  ^{1   2}, Xiaohan Ling  ^{1   2}, Jiajun Zheng  ^{1   2}, Kunkun Yu  ^{1   2}, Jing Xu  ¹, Chencheng Yao  ³, Sha Han  ³, Jiayi Liang  ¹, Huimin Feng  ¹, Lanlan Wu  ¹, Peng Li  ³, Ruhui Tian  ³, Tao Jing  ^{3   5}, Yuxin Tang  ⁴, Yingbo Dai  ⁴, Minbo Yan  ⁴, Chenchen Wang  ⁶, Zheng Li  ⁷, Zhi Zhou  ^{8   9} （Affiliations ¹ School of Life Science and Technology, ShanghaiTech University, Shanghai, China. ² Shanghai Clinical Research and Trial Center, Shanghai, China. ³ Department of Andrology, the Center for Men's Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁴ Department of Urology, Department of Interventional Medicine, Guangdong Provincial Key Laboratory of Biomedical Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, China. ⁵ Department of Andrology, the Affiliated Hospital of Qingdao University, Qingdao, China. ⁶ Shanghai Advanced Research Institute, Stem Cell and Reproductive Biology Laboratory, Chinese Academy of Sciences, Shanghai, China. chenchenwang@pku.org.cn. ⁷ Department of Andrology, the Center for Men's Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. lizhengboshi@sjtu.edu.cn. ⁸ School of Life Science and Technology, ShanghaiTech University, Shanghai, China. zhouzhi@shanghaitech.edu.cn. ⁹ Shanghai Clinical Research and Trial Center, Shanghai, China. zhouzhi@shanghaitech.edu.cn.）

出处： Nature aging 2024

摘要： Age-related changes in testicular function can impact health and well-being. The mechanisms underlying age-related testicular dysfunction, such as lat ...