作者： Mingkui Shen  ¹, Yan Hou  ², Shihui Xu  ², Jun Tan  ¹, Honggang Zhou  ¹, Qi Miao  ³, Wanheng Zhang  ³, Yazhou Chen  ^{4   5}, Nana Wang  ⁶, Yongtao Wang  ⁷ （Affiliations ¹ Department of Mini-Invasive Spinal Surgery, The Third People's Hospital of Henan Province, Zhengzhou, 450000, China. ² School of Medicine, Shanghai University, Shanghai, 200444, China. ³ Department of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China. ⁴ Medical 3D Printing Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, 450052, China. yzchenbio@zzu.edu.cn. ⁵ Henan Institute of Advanced Technology, Zhengzhou University, Zhengzhou, 450003, China. yzchenbio@zzu.edu.cn. ⁶ Department of Pediatrics, School of Medicine, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 200080, China. wang-nana@sjtu.edu.cn. ⁷ School of Medicine, Shanghai University, Shanghai, 200444, China. yongtao_wang@shu.edu.cn.）

出处： Journal of nanobiotechnology 2025

关键词： Cytoskeletal nanomechanics;Gene delivery and expression;Intelligent microarray biochips;Mechanotransduction;Patterned stem cells.

摘要： Biochips are widely applied to manipulate the geometrical morphology of stem cells in recent years. Patterned antenna-like pseudopodia are also probed ...

作者： Jie Yang  ^{1   2   3}, Xin Zeng  ^{1   2   3}, Junxia Pei  ^{1   2   4}, Zhou Su  ^{1   2   3}, Qi Liu  ^{1   2   4}, Yamei Zhang  ⁵, Yixi Yang  ^{1   2   4}, Rui Li  ^{1   2   4}, Fei Zhou  ⁶, Yu Deng  ^{7   8   9} （Affiliations ¹ Engineering Research Center of Sichuan-Tibet Traditional Medicinal Plant, Chengdu University, Chengdu, 610106, China. ² Institute of Cancer Biology and Drug Discovery, Chengdu University, Chengdu, 610106, China. ³ School of Pharmacy, Chengdu University, Chengdu, 610106, China. ⁴ School of Food and Biological Engineering, Chengdu University, Chengdu, 610106, China. ⁵ Key Laboratory of Clinical Genetics, Affiliated Hospital of Chengdu University, Chengdu, 610106, China. ⁶ Department of Oncology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, China. zhoufei.2013@hotmail.com. ⁷ Engineering Research Center of Sichuan-Tibet Traditional Medicinal Plant, Chengdu University, Chengdu, 610106, China. dengyu@cdu.edu.cn. ⁸ Institute of Cancer Biology and Drug Discovery, Chengdu University, Chengdu, 610106, China. dengyu@cdu.edu.cn. ⁹ School of Basic Medical Sciences, Chengdu University, Chengdu, 610106, China. dengyu@cdu.edu.cn.）

出处： Medical oncology (Northwood, London, England) 2025

关键词： FANCD2;Melanoma;Protocatechuic aldehyde;Synergy;Temozolomide.

摘要： Temozolomide (TMZ)-based chemotherapy is a primary regimen for melanoma patients who have failed targeted therapy or immunotherapy. However, the low r ...

作者： Yi-Bang Cheng  ¹, De-Wei An  ^{1   2   3}, Lucas S Aparicio  ⁴, Qi-Fang Huang  ¹, Yu-Ling Yu  ^{2   3}, Chang-Sheng Sheng  ¹, Teemu J Niiranen  ^{5   6}, Fang-Fei Wei  ⁷, José Boggia  ⁸, Katarzyna Stolarz-Skrzypek  ⁹, Natasza Gilis-Malinowska  ¹⁰, Valérie Tikhonoff  ¹¹, Wiktoria Wojciechowska  ⁹, Edoardo Casiglia  ¹¹, Krzysztof Narkiewicz  ¹⁰, Wen-Yi Yang  ¹², Jan Filipovský  ¹³, Kalina Kawecka-Jaszcz  ⁹, Ji-Guang Wang  ¹, Tim S Nawrot  ³, Yan Li  ¹, Jan A Staessen  ^{1   2   14   15}; International Database of Central Arterial Properties for Risk Stratification (IDCARS) Investigators （Affiliations ¹ Department of Cardiovascular Medicine, Shanghai Key Laboratory of Hypertension, Shanghai Institute of Hypertension, State Key Laboratory of Medical Genomics, National Research Centre for Translational Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. ² Non-Profit Research Association Alliance for the Promotion of Preventive Medicine, Leuven, Belgium. ³ Research Unit Environment and Health, Department of Public Health and Primary Care, University of Leuven, Leuven, Belgium. ⁴ Servicio de Clínica Médica, Sección Hipertensión Arterial, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina. ⁵ Department of Chronic Disease Prevention, Finnish Institute for Health and Welfare, Turku, Finland. ⁶ Department of Medicine, Turku University Hospital and University of Turku, Turku, Finland. ⁷ Department of Cardiology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China. ⁸ Centro de Nefrología and Departamento de Fisiopatología, Hospital de Clínicas, Universidad de la República, Montevideo, Uruguay. ⁹ First Department of Cardiology, Interventional Electrocardiology and Hypertension, Jagiellonian University Medical College, Kraków, Poland. ¹⁰ Hypertension Unit, Department of Hypertension and Diabetology, Medical University of Gdańsk, Gdańsk, Poland. ¹¹ Department of Medicine, University of Padua, Padua, Italy. ¹² Department of Cardiology, Shanghai General Hospital, Shanghai, China. ¹³ Faculty of Medicine, Charles University, Pilsen, Czech Republic. ¹⁴ Research Institute Alliance for the Promotion of Preventive Medicine, Mechelen, Belgium. ¹⁵ Biomedical Sciences Group, Faculty of Medicine, University of Leuven, Leuven, Belgium.）

出处： Journal of clinical hypertension (Greenwich, Conn.) 2025

关键词： cardiovascular risk;mortality;population science;pulse wave transit time;waveform analysis.

摘要： Prognostic significance of the timing in the cardiac cycle of the first (TP1) and second (TP2) systolic peak of the central aortic pulse wave is ill-d ...

作者： Dao-Cheng Fang  ^{1   2}, Yuan-Yuan Hu  ³, Chao Wang  ¹, Jie Fan  ⁴, Hui Wen  ⁵ （Affiliations ¹ Department of Urology, Songjiang hospital affiliated to Shanghai jiaotong university school of medicine, Shanghai, China. ² Department of Urology, Shanghai General Hospital of Nanjing Medical University, Shanghai, China. ³ Department of General Practice, Songjiang hospital affiliated to Shanghai jiaotong university school of medicine, Shanghai, China. ⁴ Department of Urology, School of Medicine, Shanghai First People's Hospital, Shanghai Jiaotong University, Shanghai, China. jief67@sina.com. ⁵ Department of Urology, Songjiang hospital affiliated to Shanghai jiaotong university school of medicine, Shanghai, China. whsimon2000@aliyun.com.）

出处： Scientific reports 2025

关键词： Blue light;Brain-kidney axis;Kidney stones;Oxidative stress.

摘要： Kidney stones, a common urological disease, may involve the brain-kidney axis in their formation, though the specific mechanism remains unclear. This ...

作者： Yu Du¹CA1;Xuehong Diao¹ （¹Department of Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China）

出处： Ultrasound in Medicine & Biology 2025

作者： Yiting Li MS¹;Xi Tan MS¹;Shu Nie MD¹;Bin Chen MS¹;Chaoshuai Zhao MS¹;Ran Liu MD¹;Zhouwei Wu PhD¹CA1 （¹Department of Dermatology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China）

出处： Journal of the American Academy of Dermatology 2025

作者： Penglin Zou ^{#  1}, Gaoxiang Fan ^{#  1}, Zheng Li  ², Yuchen Tao  ^{1   3}, Chao Jia  ¹, Hongmei Liang  ¹, Ruhui Tian  ², Qiusheng Shi  ¹, Jianlin Hu  ⁴, Rong Wu  ⁵ （Affiliations ¹ Department of Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. ² Department of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. ³ Department of Ultrasound, Huadong Hospital, Fudan University, Shanghai, 200040, China. ⁴ Department of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. hello570@126.com. ⁵ Department of Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. wurong7111@163.com.）

出处： Basic and clinical andrology 2025

关键词： Contrast-enhanced ultrasound;Hemodynamics;Male infertility;Varicocele.

摘要： Background: Hemodynamic alterations in the spermatic vein are implicated in infertility among patients with varicocele (VC). Contrast-enhanced ultraso ...

作者： Shan Liu  ¹, Siyu Tong  ², Guodong Liu  ², Shiping Wang  ², Kundong Zhang  ³, Zhengjun Qiu  ⁴ （Affiliations ¹ Department of General Surgery, Shanghai General Hospital of Nanjing Medical University, Shanghai 200080, China; The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian 223800, Jiangsu, China. ² The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian 223800, Jiangsu, China. ³ Department of General Surgery, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200080, China; Department of General Surgery, Jiuquan Branch of Shanghai General Hospital, Gansu 735099, China. Electronic address: zkd881006@163.com. ⁴ Department of General Surgery, Shanghai General Hospital of Nanjing Medical University, Shanghai 200080, China; Department of General Surgery, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200080, China. Electronic address: zhengjun.qiu@shgh.cn.）

出处： International journal of biological macromolecules 2025

关键词： Colon cancer;Hyaluronic acid;Nanoparticles.

摘要： Colon cancer (CC) is the third most common cancer globally and one of the leading causes of death. Therefore, there is an urgent need to develop an ef ...

作者： Siyu Han ^{#  1}, Shiyu Zhao ^{#  1}, Ran Zhong ^{#  1}, Peizhe Li  ¹, Yuewen Pang  ¹, Shuang He  ¹, Junyao Duan  ¹, Huijie Gong  ¹, Jing Shi  ¹, Li Liu  ², Yongji Yan  ¹ （Affiliations ¹ Department of Urology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China. ² Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Frontiers in public health 2025

关键词： burden of disease;death;disability-adjusted life-years;kidney cancer;smoking.

摘要： Purpose: Smoking is a well-established risk factor for kidney cancer. Analyzing the latest global spatio-temporal trends in the kidney cancer burden a ...

作者： Xin Zhou  ¹, Yuqing Zhao  ², Shixue Huang  ¹, Haoming Shu  ^{3   4}, Yinuo Zhang  ¹, Haiyuan Yang  ^{3   4}, Yilong Ren  ^{3   4}, Xuhui Zhou  ^{1   4}, Wei Liu  ¹, Tengfei Song  ¹, Jianquan Zhao  ¹, Jun Ma  ^{3   4} （Affiliations ¹ Department of Orthopedics, Changzheng Hospital, The Second Affiliated Hospital of Naval Medical University, Shanghai 200003, China. ² Department of Neurosurgery, Changzheng Hospital, The Second Affiliated Hospital of Naval Medical University, Shanghai 200003, China. ³ Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. ⁴ Translational Research Centre of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.）

出处： International journal of biological sciences 2025

关键词： GPX4;TRIM32;autophagic degradation;neuronal ferroptosis;ubiquitination.

摘要： Ferroptosis, characterized by iron-dependent phospholipid peroxidation, is recognized as one of the cell death pathways activated following spinal cor ...