作者： Lin-Yi Shen M.M^1,2;Li Sun M.M^3,2;Wei-Xing Li M.M¹;Qian-Ru Li Ph.D¹;Yi-Xin Wen M.M⁴;Yi-Wen Hu Ph.D³;Yang Sun Ph.D¹;Ji-Wu Chen M.D., Ph.D⁵;Hong-Yun Li M.D., Ph.D¹CA1 （¹Sports Medicine Institution of Fudan University; Department of Sports Medicine and Arthroscopy Surgery, Huashan Hospital, Fudan University, Shanghai, China, 200040;²Lin-Yi Shen and Li Sun contributed equally to this work and are co-first authors.;³Department of Radiology and Institute of Medical Functional and Molecular Imaging, Huashan Hospital, Fudan University, Shanghai, China, 200040;⁴Department of Orthopedics, Wuhan Fifth Hospital, Jianghan University, Wuhan, China, 430050;⁵Department of Sports Medicine, Shanghai General Hospital, Shanghai Jiao Tong University; School of Medicine, Shanghai Jiao Tong University, Shanghai, China, 200080）

出处： Arthroscopy: The Journal of Arthroscopic & Related Surgery 2025

摘要： Purpose To explore the healing status of interportal capsulotomies without repair after arthroscopy in patients with femoroacetabular impingement synd ...

作者： Xin Huang^1,2,3,4CA1;Xuetong Hou^5,2;Yizhen Li^6,7;Jun J. Yang^7,8,9,10;Jiyang Yu¹¹CA2 （¹Precision Research Center for Refractory Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, China;²These authors contributed equally;³Technical contact;⁴Lead contact;⁵Institute of Health and Medicine, Hefei Comprehensive National Science Center, Hefei, Anhui 230601, China;⁶Department of Hematology, Children’s Hospital of Soochow University, Soochow University, Suzhou, Jiangsu 215003, China;⁷Pediatric Hematology & Oncology Key Laboratory of Higher Education Institutions in Jiangsu Province, Suzhou, Jiangsu 215003, China;⁸Division of Pharmaceutical Sciences, Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA;⁹Department of Oncology, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA;¹⁰Hematological Malignancies Program, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA;¹¹Department of Computational Biology, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA）

出处： STAR Protocols 2025

摘要： Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.

作者： Gayathri Swaminathan¹;Yu-Chu Lin¹;Jianbo Ni^1,2;Asna Khalid¹;Cheng-Yu Tsai¹;Ying Ding³;Na Bo³;Judy-April Murayi⁴;Thottala Jayaraman⁵;Ronald Poropatich⁶;Rita Bottino⁷;Georgios I. Papachristou⁸;Sunil G. Sheth⁹;Li Wen¹⁰;Monique T. Barakat^1,11;Adam R. Frymoyer¹²;Mang Yu¹CA1;Sohail Z. Husain¹CA2 （¹Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Stanford University, School of Medicine, Stanford, CA, USA;²Department of Gastroenterology and Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;³Department of Biostatistics, University of Pittsburgh, Pittsburgh, PA, USA;⁴Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Nationwide Children's Hospital, Columbus, OH, USA;⁵Department of Oral and Craniofacial Sciences, School of Dental Medicine, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA;⁶University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA;⁷Imagine Islet Center, Imagine Pharma, 1401 Forbes Avenue, Pittsburgh, PA, USA;⁸The Ohio State University Wexner Medical Center, Columbus, OH, USA;⁹Beth Israel Deaconess Medical Center, Boston, MA, USA;¹⁰Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China;¹¹Division of Gastroenterology and Hepatology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA;¹²Division of Neonatology, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA）

出处： Pancreatology 2025

摘要： Objective Acute pancreatitis is a frequent, burdensome adverse event of endoscopic retrograde cholangiography (ERCP). Rectal nonsteroidal anti-inflamm ...

作者： Wei Huang  ¹, Chengcheng Zhang, Weibiao Zeng, Dong Lin, Jiang Fan, Liang Wu （Affiliation ¹ Department of Thoracic Surgery, Shanghai General Hospital Shanghai Jiao Tong University School of Medicine, Shanghai, PRC.）

出处： International journal of surgery (London, England) 2025

摘要： Background: The localization of pulmonary nodules is crucial for surgical intervention. However, a safe, simple, and efficient method remains elusive. ...

作者： Meiling Wang  ¹, Qiqi Zhang  ², Jing Wang  ¹ （Affiliations ¹ Department of Gastroenterology, Songjiang Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Journal of gastroenterology and hepatology 2025

关键词： PCED1A;colorectal cancer;diagnostic marker;hepatocellular carcinoma;immune infiltration.

摘要： Background: Hepatocellular carcinoma (HCC) and colorectal cancer (CRC) pose a significant threat to human health worldwide, characterized by intricate ...

作者： Xiaoting Shan  ^{1   2}, Ying Cai  ^{1   2   3}, Binyu Zhu  ^{1   2}, Xujie Sun  ^{1   2}, Lingli Zhou  ¹, Zhiwen Zhao  ^{1   2}, Yaping Li  ^{1   2   3   4}, Dangge Wang  ⁵ （Affiliations ¹ State Key Laboratory of Drug Research & Center of Pharmaceutics, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. ² University of Chinese Academy of Sciences, No.19A Yuquan Road, Beijing, 100049, China. ³ Yantai Key Laboratory of Nanomedicine & Advanced Preparations, Yantai Institute of Materia Medica, Shandong, 264000, China. ⁴ Shandong Laboratory of Yantai Drug Discovery, Bohai Rim Advanced Research Institute for Drug Discovery, Yantai, 264000, China. ⁵ Precision Research Center for Refractory Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China.）

出处： Advanced healthcare materials 2025

关键词： cancer chemoimmunotherapy;computer‐aided design;nanoparticles;pharmacophore hybridization;triple‐negative breast cancer.

摘要： The rational design of self-assembled compounds is crucial for the highly efficient development of carrier-free nanomedicines. Herein, based on comput ...

作者： Bo Pan ^{#  1   2}, Yiming Pan ^{#  1   2}, Yu-Song Huang ^{#  3}, Meng Yi  ¹, Yuwei Hu  ^{1   2}, Xiaoyu Lian  ^{1   2}, Hui-Zhong Shi  ⁴, Mingwei Wang  ^{1   2}, Guifen Xiang  ^{1   2   5}, Wen-Yi Yang  ⁶, Zhong Liu  ^{7   8   9}, Fangfang Xia  ¹⁰ （Affiliations ¹ Institute of Blood Transfusion Institution, Chinese Academy of Medical Sciences and Peking Union Medical College, 26 Huacai Rd, Longtan Industry Zone, Chenghua District, Chengdu, Sichuan, China. ² Key laboratory of transfusion adverse reactions, Chinese Academy of Medical Sciences, Chengdu, 610052, China. ³ Department of Cardiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Haining Rd 100, Shanghai, 200080, China. ⁴ Department of Hematology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 100 Haining Road, Shanghai, 200080, China. ⁵ School of Public Health, Anhui Medical University, Hefei, 230032, China. ⁶ Department of Cardiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Haining Rd 100, Shanghai, 200080, China. wenyi.yang@shgh.cn. ⁷ Institute of Blood Transfusion Institution, Chinese Academy of Medical Sciences and Peking Union Medical College, 26 Huacai Rd, Longtan Industry Zone, Chenghua District, Chengdu, Sichuan, China. liuz@ibt.pumc.edu.cn. ⁸ Key laboratory of transfusion adverse reactions, Chinese Academy of Medical Sciences, Chengdu, 610052, China. liuz@ibt.pumc.edu.cn. ⁹ School of Public Health, Anhui Medical University, Hefei, 230032, China. liuz@ibt.pumc.edu.cn. ¹⁰ Department of Anesthesiology, the First Affiliated Hospital of Wenzhou Medical University, Zhejiang, China. helenxia4271@163.com.）

出处： BMC psychiatry 2025

关键词： Depression;Geographical region;Meta-analysis;Microbiome–targeted therapy;Patient characteristics;Precision medicine.

摘要： Background: The study aimed to comprehensively analyze and establish a framework for evaluating the efficacy of microbiome-targeted treatment (MTT) fo ...

作者： Yikeng Huang  ¹, Zhi Zheng  ^{1   2   3}, Haibing Chen  ⁴, Chufeng Gu  ⁵ （Affiliations ¹ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine; National Clinical Research Center for Eye Diseases; Shanghai Clinical Research Center for Eye Diseases; Shanghai Key Clinical Specialty; Shanghai Key Laboratory of Ocular Fundus Diseases; Shanghai Engineering Center for Visual Science and Photomedicine; Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China. ² Ningde Municipal Hospital, Ningde Normal University, Ningde, Fujian, China. ³ Fujian Medical University, Fuzhou, Fujian, China. ⁴ Department of Endocrinology and Metabolism, Shanghai 10th People's Hospital, School of Medicine, Tongji University, Shanghai, China. hbchen@tongji.edu.cn. ⁵ Department of Ophthalmology, Shengli Clinical College of Fujian Medical University; Fuzhou University Affiliated Provincial Hospital, School of Medicine, Fuzhou University, Fuzhou, Fujian, China. guchufeng@fjsl.com.cn.）

出处： Diabetology & metabolic syndrome 2025

关键词： Diabetes inequity;Diabetic nephropathy;Diabetic peripheral neuropathy;Diabetic retinopathy;Socioeconomic status;UK Biobank.

摘要： Background: Prior studies on the link between socioeconomic status (SES) and diabetic microvascular complications have been inconclusive. This study a ...

作者： Yuepeng An ^{#  1}, Fu Zhao ^{#  2}, Hongling Jia ^{#  3}, Siyu Meng  ⁴, Ziwei Zhang ^{#  5}, Shuxiao Li ^{#  6   7}, Jiusi Zhao ^{#  8} （Affiliations ¹ The First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, 150040, China. ² Shandong University of Traditional Chinese Medicine, Jinan, 250014, China. ³ The First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, 250014, Shandong, China. ⁴ Northeast International Hospital, Shenyang, 110180, China. ⁵ Department of Plastic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China. andreavaimukas@sjtu.edu.cn. ⁶ Department of Burns and Plastic Reconstructive Surgery, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, 533000, Guangxi Province, China. 977817863@qq.com. ⁷ Life Science and Clinical Medicine Research Center, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, 533000, Guangxi Province, China. 977817863@qq.com. ⁸ The First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, 150040, China. zjs_0807999@163.com.）

出处： Discover oncology 2025

关键词： Macrophages;Melanoma;Oxidative phosphorylation;Programmed cell death;Single-cell RNA sequencing;Tumor metastasis.

摘要： Melanoma is an aggressive type of skin cancer that arises from melanocytes, the cells responsible for producing skin pigment. In contrast to non-melan ...

作者： Xin Luo  ¹, Kan Chen  ², Jie Zhang  ², Zhilu Yao  ³, Chuanyong Guo  ², Ying Qu  ¹, Lungen Lu  ¹, Yuqing Mao  ¹ （Affiliations ¹ Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China. ³ Department of Gastroenterology, Jing'an District Zhabei Central Hospital, Shanghai, China.）

出处： FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025

关键词： exosomes;ferroptosis;ghrelin;liver fibrosis;lncMALAT1.

摘要： Ghrelin reduced the profibrotic effect of IHC-Exo in liver fibrosis by regulating lncMALAT1/GPX4 pathway mediated HSCs ferroptosis. Triggering HSCs fe ...