作者： Hanqing Liu;Yihui Wang;Qianqian Le;Jiajia Tong;Honglin Wang （Precision Research Center for Refractory Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, P. R. China Shanghai Institute of Immunology, Precision Research Center for Refractory Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China Precision Research Center for Refractory Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China Full correspondence Dr. Honglin Wang, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, China, No. 650 Xin Songjiang Road, Songjiang District, 201620 Shanghai, P. R. China）

出处： European Journal of Immunology 2024

关键词： CD8+ T cells;Cytokine axis;Treatment;Vitiligo

摘要： Vitiligo is a disease featuring distinct white patches that result from melanocyte destruction. The overall pathogenesis of vitiligo remains to be elu ...

作者： Wu, Yue^a,b;Liu, Xin^a,b;Liu, Yuying^a,b;Qian, Wenzhe^a,b;Huang, Liandi^a,b;Wu, Yixiang^a,b;Wang, Xuetong^a,b;Yuan, Ying^a,b;Ke, Bilian^a,cCAa （^aDepartment of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 100 Haining Road, Hongkou District, Shanghai, China;^bNational Clinical Research Center for Eye Diseases, Shanghai, China;^cDepartment of Ophthalmology, Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China）

出处： Ophthalmology and Therapy 2024

关键词： Anisomyopia;Children;Macular curvature;Microvascularity;Myopia;Optical coherence tomography

摘要： Introduction: To evaluate the intraocular differences in optical coherence tomography (OCT)-based macular curvature index (MCI) among children with an ...

作者： Hongjie Chen ^{#  1}, Peng Lai ^{#  1}, Haiming Lu ^{#  1}, Jun Zhu  ², Weilin Sang  ¹, Cong Wang  ¹, Yiming Zhong  ³, Libo Zhu  ⁴, Jinzhong Ma  ⁵ （Affiliations ¹ Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. ² Department of Neurosurgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China. ³ Department of Orthopedics, Peking University Third Hospital, Beijing, 100191, China. ⁴ Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. libozhu2018@163.com. ⁵ Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. majinzhong1963@sina.com.）

出处： Journal of orthopaedic surgery and research 2024

关键词： COVID-19;Case-crossover study;Groin pain;Total hip arthroplasty (THA).

摘要： Background: The coronavirus disease 2019 (COVID-19) rapidly spreads worldwide and causes more suffering. The relation about the aggravation of inguina ...

作者： Yan, Weiwei^a;Xie, Chengmei^a;Sun, Sijun^a,b;Zheng, Quan^c;Wang, Jingyi^d;Wang, Zihao^e;Man, Cheuk-Him^f;Wang, Haiyan^d;Yang, Yunfan^g;Wang, Tianshi^h;Shi, Leilei^a;Zhang, Shengjie^aCAa;Huang, Chen^bCAb;Xu, ShuangnianⁱCAc;Wang, Yi-Ping^a,eCAd （^aPrecision Research Center for Refractory Diseases, Institute for Clinical Research, Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China;^bDepartment of Gastrointestinal Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China;^cCenter for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China;^dDepartment of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China;^eInstitutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, 200032, China;^fDivision of Haematology, Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong;^gDepartment of Cell Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, 250012, China;^hDepartment of Biochemistry and Molecular Cell Biology, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China;ⁱDepartment of Hematology, Southwest Hospital, Army Medical University, Chongqing, 400038, China）

出处： EMBO Journal 2024

关键词： FMS-like Tyrosine Kinase 3;Lysine Succinylation;Mitochondrial Biogenesis;Mitochondrial RNA Polymerase;Succinate-CoA Ligase

摘要： Mitochondria are cellular powerhouses that generate energy through the electron transport chain (ETC). The mitochondrial genome (mtDNA) encodes essent ...

作者： Li, Jingjie^aCAa;Qin, Zuoshu^a;Li, Yunqi^b;Huang, Baozhu^a;Xiao, Qimeng^a;Chen, Peiqin^a;Luo, Yifan^a;Zheng, Wenxin^c,d,e;Zhang, Tao^fCAb;Zhang, Zhenbo^a,gCAc （^aPrecision Research Center for Refractory Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China;^bShanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China;^cDepartment of Pathology, University of Texas Southwestern Medical Center, Dallas, 75390, TX, United States;^dDepartment of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, 75390, TX, United States;^eSimon Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, 75390, TX, United States;^fDepartment of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China;^gReproductive Medicine Center, Department of Obstetrics and Gynecology, Tongji hospital, School of Medicine, Tongji University, Shanghai, 200065, China）

出处： Advanced Science 2024

关键词： endometrial cancer;IDH1 phosphorylation;p38;progestin resistance

摘要： The progestin regimen is one of the main therapeutic strategies for women with endometrial cancer who undergo conservative management. Although many p ...

作者： Hu, Guangyi^a,c,d,e;Gu, Liping^b;Wang, Ruonan^a,c,d,e;Jian, Qizhi^a,c,d,e;Lv, Kangjia^a,c,d,e;Xia, Mengxue^a,c,d,e;Lai, Mengyu^b;Shen, Tingting^b;Hu, Jing^a,c,d,e;Yang, Sen^f,g;Ye, Cunqi^f,g;Zhang, Xiaonan^a;Wang, Yufan^bCAa;Xu, Xun^a,c,d,eCAb;Zhang, Fang^a,b,c,d,eCAc （^aNational Clinical Research Center for Eye Diseases, Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China;^bDepartment of Endocrinology and Metabolism, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China;^cEye Institute of Shanghai Jiao Tong University School, Shanghai, 200080, China;^dShanghai Key Laboratory of Fundus Diseases, Shanghai, 200080, China;^eShanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, 200080, China;^fZhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, 310058, China;^gKidney Disease Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China）

出处： Science Bulletin 2024

关键词： Biomarker;Biomarker-based treatment;Diabetic retinopathy;Ethanolamine;Glucose-well-controlled diabetic patients;HbA1c

摘要： Diabetic retinopathy (DR) is the leading cause of blindness among the working-age population. Although controlling blood glucose levels effectively re ...

作者： Liu, Kaiyuan^a;Zan, Pengfei^a;Li, Zihua^b;Lu, Hengli^b;Liu, Peng^c;Zhang, Li^b;Wang, Hongsheng^a;Ma, Xiaojun^a;Chen, Feng^dCAa;Zhao, Jing^cCAb;Sun, Wei^aCAc （^aDepartment of Bone Tumor Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China;^bSchool of Medicine, Tongji University, Shanghai, 200072, China;^cScientific Research Center, The Seventh Affiliated Hospital of Sun Yat-Sen University, No. 628 Zhenyuan Road, Guangdong, Shenzhen, 518107, China;^dShanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Stomatological Hospital and School of Stomatology, Fudan University, Shanghai, 200001, China）

出处： Advanced Healthcare Materials 2024

关键词： cGAS-STING;immunotherapy;mild-temperature PTT;osteosarcoma;pyroptosis

摘要： The immunosuppressive tumor microenvironment (ITME) of osteosarcoma (OS) poses a significant obstacle to the efficacy of existing immunotherapies. Des ...

作者： Han, Xiao-Yan^a,b;Kong, Ling-Jie^b;Li, Duo^a,c;Tong, Ming^b;Li, Xiu-Miao^a,c;Zhao, Chen^b;Jiang, Qin^a,cCAa;Yan, Biao^dCAb （^aThe Affiliated Eye Hospital, Nanjing Medical University, Nanjing, 210000, China;^bEye Institute, Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China;^cThe Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, 210000, China;^dDepartment of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China）

出处： Theranostics 2024

关键词： Angiogenesis;Endothelial metabolism;Glycolytic flux;Ocular neovascular disease;tsRNAs

摘要： Rationale: Current treatments for ocular angiogenesis primarily focus on blocking the activity of vascular endothelial growth factor (VEGF), but unfav ...

作者： Zhang, Yun^a;Tian, Ge^a;Sun, Xueni^a;Yang, Xiaoli^a;Zhang, Yi^a;Tan, Wenqing^a;Duan, Liangwei^aCAa;Gao, Shunxiang^cCAb;Yu, Junping^a,bCAc （^aLaboratory of Infection and Immunology, School of Medical Technology, Xinxiang Medical University, Xinxiang, 453003, China;^bCAS Key Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China;^cDepartment of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China）

出处： Microchimica Acta 2024

关键词： Chicken IgY;S. aureus;Specificity;Wheat germ agglutinin

摘要： A novel colorimetric platform was designed for the determination of S. aureus by utilizing a dual-recognition strategy, where wheat germ agglutinin (W ...

作者： Dong, Lingkai^a;Liu, Minchao^a;Fang, Meng^b;Lu, Qianqian^a;Li, Xingjin^a;Ma, Yanming^a;Zhao, Tiancong^aCAa （^aSchool of Chemistry and Materials, Department of Chemistry, Laboratory of Advanced Materials and Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, State Key Laboratory of Molecular Engineering of Polymers, Collaborative Innovation Center of Chemistry for Energy Materials (2011-iChEM), Fudan University, Shanghai, 200433, China;^bDepartment of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China）

出处： Small 2024

关键词： artificial antigen presenting cell;emulsion;polydopamine;polymerization;vesicle

摘要： Albeit microemulsion systems have emerged as efficient platforms for fabricating tunable nano/microstructures, lack of understanding on the emulsion-i ...