作者： Jie Jiang  ¹, Zai Luo  ¹, Hao-Liang Zhang  ¹, Zheng-Jun Qiu  ¹, Chen Huang  ¹ （Affiliation ¹ Department of Gastrointestinal Surgery,Shanghai General Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200080,China.）

出处： Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 2024

关键词： circular RNA;internal ribosome entry site;protein;protein bait.

摘要： Circular RNAs(CircRNAs)are a class of non-coding RNAs with a covalently closed-loop structure,high stability,and tissue specificity,with the productio ...

作者： Dingyi Rong¹;Zhongyin Zhao¹;Yue Wu²;Bilian Ke^2,3;Binging Ni¹ （¹Department of Electrical Engineering, Shanghai Jiao Tong University, Shanghai, China ²Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China ³Department of Ophthalmology, Ren Ji Hospital, School of Medicine, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China）

出处： IEEE Transactions on Medical Imaging 2024

关键词： Lenses;Surfaces;Cornea;Force;Elongation;Geometry;Predictive models

摘要： While orthokeratology (OK) has shown effective to slow the progression of myopia, it remains unknown how spatially distributed structural stress/tensi ...

作者： Xiaorui Cao  ¹, Linli Xue  ¹, Xiuju Yu  ¹, Yi Yan  ¹, Jiayin Lu  ¹, Xiaomao Luo  ¹, Haidong Wang  ¹, Juan Wang  ^{1   2} （Affiliations ¹ College of Veterinary Medicine, Shanxi Agricultural University, Taigu, Shanxi 030801, China. ² Department of Nephrology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200080, China.）

出处： Aging 2024

关键词： exosomes;miR-140-5p;muscle injury repair;muscle satellite cells;regeneration.

摘要： Muscle satellite cells (SCs) play a crucial role in the regeneration and repair of skeletal muscle injuries. Previous studies have shown that myogenic ...

作者： Shengyong Diao  ¹, Ziting Yin  ¹, Xinjian Chen  ^{1   2}, Menghan Li  ³, Weifang Zhu  ¹, Muhammad Mateen  ¹, Xun Xu  ³, Fei Shi  ¹, Ying Fan  ³ （Affiliations ¹ MIPAV Lab, the School of Electronics and Information Engineering, Soochow University, Suzhou, China. ² The State Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou, China. ³ Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Medical physics 2024

关键词： adversarial learning;deep learning;retinal OCT image segmentation;unsupervised domain adaptation.

摘要： Background: Deep learning based optical coherence tomography (OCT) segmentation methods have achieved excellent results, allowing quantitative analysi ...

作者： Lijuan Huang^1,2;Xueqing Bai²;Yan Xie²;Yunyu Zhou²;Jin Wu²;Ningdong Li^1,2,3CA1 （¹Department of Ophthalmology, The Second Affiliated Hospital of Fujian Medical University, 362000, Quanzhou, China;²Department of Ophthalmology, Beijing Children’s Hospital, Capital Medical University, 100045, Beijing, China;³Department of Ophthalmology, Shanghai General Hospital, 200940, Shanghai, China）

出处： Orphanet Journal of Rare Diseases 2024

关键词： Congenital stationary night blindness;Myopia;Strabismus;Mutation

摘要： Background Congenital stationary night blindness (CSNB) is an inherited retinal disorder. Most of patients have myopia. This study aims to describe t ...

作者： Hang Zhao  ¹, Wenhua Li  ², Xin Zhou  ³, Liang Pan  ³, Yun Feng  ⁴, Pingyu Gao  ⁵, Jie Ji  ⁶, Huanyan Zhang  ⁶, Kai Zhao  ³, Chi Wang  ⁷, Zhanjun Lu  ^{3   4} （Affiliations ¹ Department of Gastroenterology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai, China. ² Department of Gastroenterology, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ Department of Gastroenterology, Jintan Hospital, Jiangsu University, Changzhou, China. ⁴ Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁵ Pathology Center, Jintan Hospital, Jiangsu University, Zhenjiang, China. ⁶ Clinical Laboratory, Jintan Hospital, Jiangsu University, Zhenjiang, China. ⁷ Department of Precision Mechanical Engineering, Shanghai University, Shanghai, China.）

出处： Journal of innate immunity 2024

关键词： CXCL1;Colitis;Gut microbiota;Inflammation;Neutrophil.

摘要： Introduction: C-X-C motif chemokine ligand 1 (CXCL1) is a potent neutrophil chemoattractant that plays a pivotal role in recruiting neutrophils during ...

作者： Tianjiao Guo  ^{1   2   3}, Kun Liu  ^{4   5   6}, Haidong Zou  ^{4   5   6}, Xun Xu  ^{4   5   6}, Jie Yang  ², Qi Yu  ^{4   5   6} （Affiliations ¹ Institute of Medical Robotics, Shanghai Jiao Tong University, China. ² Department of Automation, Institute of Image Processing and Pattern Recognition, Shanghai Jiao Tong University, China. ³ School of Biomedical Engineering, Shanghai Jiao Tong University, China. ⁴ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, China. ⁵ National Clinical Research Center for Eye Diseases, Shanghai, China. ⁶ Shanghai Clinical Research Center for Eye Diseases, China.）

出处： Digital health 2024

关键词： Color fundus photography;deep learning;image quality assessment;pre-diagnosis;screening.

摘要： Purpose: Color fundus photography is widely used in clinical and screening settings for eye diseases. Poor image quality greatly affects the reliabili ...

作者： Hongwei Shi  ¹, Xiaojing Hao  ¹, Yaqin Sun  ¹, Yating Zhao  ¹, Yue Wang  ¹, Xiaorui Cao  ¹, Zeen Gong  ¹, Shusen Ji  ¹, Jiayin Lu  ¹, Yi Yan  ¹, Xiuju Yu  ¹, Xiaomao Luo  ¹, Juan Wang  ², Haidong Wang  ¹ （Affiliations ¹ College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong, P.R. China. ² Department of Nephrology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, P.R. China.）

出处： Acta physiologica (Oxford, England) 2024

关键词： AMPK;browning;exercise;extracellular vesicle;integrin αV;irisin.

摘要： Aim: Exercise can reduce body weight and promote white fat browning, but the underlying mechanisms remain largely unknown. This study investigated the ...

作者： Yanzheng Chen  ¹, Xueliang Zhang  ¹, Qing Wang  ², Chang Du  ^{3   4}, Chang-Ming Dong  ¹ （Affiliations ¹ School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240, P. R. China. cmdong@sjtu.edu.cn. ² Department of Stomatology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 200080, P. R. China. ³ Clinical Cancer Institute, Center for Translational Medicine, Naval Military Medical University, Shanghai, 200433, P. R. China. cdu@shsci.org. ⁴ State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200240, P. R. China.）

出处： Biomaterials science 2024

摘要： Regulating the wound microenvironment to promote proliferation, vascularization, and wound healing is challenging for hemostats and wound dressings. H ...

作者： Shengzhou Li  ¹, Yiming Chen  ², Xiangqian Cao  ¹, Chenkai Yang  ¹, Wei Li  ³, Bing Shen  ^{1   4} （Affiliations ¹ Department of Urology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 200080, Shanghai, China. ² Department of Orthopedics, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 200080, Shanghai, China. ³ Department of Nanomedicine & Shanghai Key Lab of Cell Engineering, Naval Medical University, 200433, Shanghai, China. ⁴ Shanghai Tenth People's Hospital of Tongji University, 200072, Shanghai, China.）

出处： Nanomedicine (London, England) 2024

关键词： graft function evaluation;immunosuppressants;kidney transplantation;nanotechnology;organ preservation.

摘要： Kidney transplantation is a crucial treatment option for end-stage renal disease patients, but challenges related to graft function, rejection and imm ...