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作者: Junran Sun MD1,2,3,4,5;Yuanyuan Gong MD1,2,3,4,5;Suqin Yu MD1,2,3,4,51Department of Ophthalmology, Shanghai General Hospital (Shanghai First People’s Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China;2National Clinical Research Center for Ophthalmic Diseases, Shanghai, China;3Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China;4Shanghai Key Laboratory of Fundus Diseases, Shanghai, China;5Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Disease)

出处: Ophthalmology 2024

作者: Keyu Pan1,2,3;Huixun Jia4,5,3;Renjie Chen5;Chang Su6;Huijun Wang6CA1;Tao Zhang1,2,7CA2;Zhenyu Wu5CA31Department of Biostatistics, School of Public Health, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.;2Institute for Medical Dataology, Shandong University, Jinan 250012, China;3These authors contributed equally to this work.;4National Clinical Research Center for Ophthalmic Diseases; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People’s Hospital), Shanghai Jiao Tong University, School of Medicine, Shanghai, China; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China;5School of Public Health, Fudan University, Shanghai 200032, China;6National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China;7Clinical Research Center of Shandong University, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan 250012, China)

出处: Ecotoxicology and Environmental Safety 2024

关键词: Polychlorinated biphenyls;Diabetes;Restricted cubic spline;Weighted quantile sum regression;Bayesian kernel machine regression

摘要: Background Whether and to what extent the impact of exposure to various polychlorinated biphenyls (PCBs) congeners on diabetes, as well as the importa ...

作者: Yunqing Liu1,2;Jinlei Liu1,2;Yuanyuan Tian1,2;Yanrui Jin1,2;Zhiyuan Li1,2;Liqun Zhao3CA1;Chengliang Liu1,2CA21School of Mechanical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, China;2MoE Key Lab of Artificial Intelligence, AI Institute, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, China;3Department of Cardiology, Shanghai First People’s Hospital Affiliated with Shanghai Jiao Tong University, 100 Haining Road, Shanghai 200080, China)

出处: Applied Soft Computing 2024

摘要: Real-time electrocardiogram (ECG) monitoring through portable or wearable devices is critical for detecting lethal arrhythmias. Despite the accuracy o ...

作者: Meng He1;Wenqian Wei1;Yichen Zhang2;Zhouxia Xiang1;Dan Peng1;Ayijiaken Kasimumali1;Shu Rong1CA11Department of Nephrology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 200080, Shanghai, China;2Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 200080, Shanghai, China)

出处: Journal of Translational Medicine 2024

关键词: SCFAs;CKD;Gut microbial metabolites;Inflammatory responses;Oxidative stress

摘要: The global incidence of Chronic Kidney Disease (CKD) is steadily escalating, with discernible linkage to the intricate terrain of intestinal microecol ...

作者: He-Ming Zhou1,2;Da-Hong Chen1,2;Wen-Jing Diao1;Ya-Fei Wu1;Ji-Gang Zhang3;Lin Zhong4;Zhong-Yi Jiang4;Xue Zhang1,5;Gao-Lin Liu1,5;Qin Li1,5CA11Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 100 Haining Road, Shanghai, 200080, PR China;2HM Zhou and DH Chen contributed equally to this study.;3Clinical Research Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 100 Haining Road, Shanghai, 200080, PR China;4Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 100 Haining Road, Shanghai, 200080, PR China;5Shanghai Eye Diseases Prevention & Treatment Center / Shanghai Eye Hospital, Shanghai, 200040, PR China)

出处: Experimental Cell Research 2024

关键词: RhoA;Regorafenib;Drug resistance;Stemness;HCC

摘要: Patients with hepatocellular carcinoma (HCC) are vulnerable to drug resistance. Although drug resistance has been taken much attention to HCC therapy, ...

作者: Xiao Han1,2,3;Jingpiao Bao1,2,3;Jianbo Ni1,2;Bin Li1,2;Pengli Song1,2;Rong Wan1,2;Xingpeng Wang1,2;Guoyong Hu1,2CA1;Congying Chen1,2CA21Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;2Shanghai Key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai Jiao Tong University School of Medicine, Shanghai, China;3These authors contributed equally to this work.)

出处: Journal of Ethnopharmacology 2024

摘要: Ethnopharmacological relevance Herbal formulas from Traditional Chinese Medicine are common and well-established practice for treating acute pancreati ...

作者: Jingwen Ren1,2;Yuanyuan Li1,3;Xueyuan Zhang4;Min Xiong1;Heng Zhang1;Lingyue An1;Ying Cao3;Shujie Xia5;Guangheng Luo1,3;Ye Tian1,3CA11Department of Urology, Guizhou Provincial People’s Hospital, Guiyang, China;2Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China;3Guizhou University School of Medicine, Guiyang, China;4Zunyi Medical University, Zunyi, China;5Department of Urology, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, China)

出处: BMC Urology 2024

关键词: Prostatic fibrosis;Metabolic syndrome;Lower urinary tract symptoms

摘要: Background Prostatic fibrosis, characterized by the accumulation of myofibroblasts and collagen deposition, is closely associated with LUTS and may l ...

作者: Hongjie Chen1,2;Yiming Zhong3,2;Weilin Sang1;Cong Wang1;Haiming Lu1;Peng Lai1;Libo Zhu1CA1;Jinzhong Ma1CA21Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China;2These authors contributed equally to this work.;3Department of Orthopedics, Peking University Third Hospital, Beijing, 100191, China)

出处: Biochemical and Biophysical Research Communications 2024

摘要: Osteoarthritis is highly prevalent joint disease; however, effective treatments are lacking. Protopine (PTP) is an isoquinoline alkaloid with potent a ...

作者: Jin Wei1,2,3,4,5;Chong Chen1,2,3,4,5;Yinchen Shen1,2,3,4,5;Fang Li6;Shu Yiyang7;Haiyun Liu1,2,3,4,5CA11Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 20080, Shanghai, China;2National Clinical Research Center for Eye Diseases, 20080, Shanghai, China;3Shanghai Key Laboratory of Ocular Fundus Diseases, 20080, Shanghai, China;4Shanghai Engineering Center for Visual Science and Photomedicine, 20080, Shanghai, China;5Shanghai engineering center for precise diagnosis and treatment of eye diseases, 20080, Shanghai, China;6Department of Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 20080, Shanghai, China;7Department of Ophthalmology, Tongji Hospital, School of Medicine, Tongji University, 200065, Shanghai, China)

出处: BMC Ophthalmology 2024

关键词: SMI;Ultrawide-field OCTA;Diabetic retinopathy;Hemodynamics

摘要: Aims To find potential relation between retrobulbar vessels and fundus microvessels and to detect sensitive and effective clinical indicators in pred ...

作者: Tian Niu1,2,3,4,5;Xin Shi1,2,3,4,5;Xijian Liu6;Haiyan Wang1,2,3,4,5;Kun Liu1,2,3,4,5CA1;Yupeng Xu1,2,3,4,5CA21Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 200080, Shanghai, China;2National Clinical Research Center for Eye Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 200080, Shanghai, China;3Shanghai Key Laboratory of Ocular Fundus Diseases, 200080, Shanghai, China;4Shanghai Engineering Center for Visual Science and Photomedicine, 200080, Shanghai, China;5Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, 200080, Shanghai, China;6School of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, 201620, Shanghai, China)

出处: Molecular Medicine 2024

关键词: Diabetic retinopathy;Porous Se@SiO2 nanospheres;Lipid peroxidation;Inflammation

摘要: Background Lipid peroxidation is a characteristic metabolic manifestation of diabetic retinopathy (DR) that causes inflammation, eventually leading t ...

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