作者： Guobin Qi  ¹, Xianglong Liu  ^{1   2}, Leilei Shi  ³, Jiahao Zhuang  ¹, Bin Liu  ^{1   2   4} （Affiliations ¹ Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore, 117585, Singapore. ² Joint School of National University of Singapore and Tianjin University, International Campus of Tianjin University, Binhai New City, Fuzhou, 350207, China. ³ Precision Research Center for Refractory Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201600, China. ⁴ Institute for Functional Intelligent Materials, National University of Singapore, Blk S9, Level 9, 4 Science Drive 2, Singapore, 117544, Singapore.）

出处： Advanced materials (Deerfield Beach, Fla.) 2024

关键词： ATRP;bacteria-templated polymer;bacterial infection;target depletion.

摘要： Selective and targeted removal of individual species or strains of bacteria from complex communities can be desirable over traditional and broadly act ...

作者： Lingxuan Zhu  ¹, Weiming Mou  ², Jiarui Xie  ³, Peng Luo  ³, Rui Chen  ⁴ （Affiliations ¹ Department of Urology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, 160 Pujian Road, Shanghai, 200127, China; Department of Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China. ² Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ Department of Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China. ⁴ Department of Urology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, 160 Pujian Road, Shanghai, 200127, China. Electronic address: drchenrui@foxmail.com.）

出处： Resuscitation 2024

作者： Bing Zhuang  ¹, Liangying Gan  ², Bin Liu  ³, Weijie Yuan  ⁴, Ming Shi  ⁵, Ai Peng  ⁶, Lihua Wang  ⁷, Xiaolan Chen  ⁸, Tongqiang Liu  ⁹, Shiying Zhang  ¹⁰, Song Wang  ¹¹, Qing Gao  ¹², Baoxing Wang  ¹³, Huixiao Zheng  ¹⁴, Changhua Liu  ¹⁵, Yuan Luo  ¹, Hong Ye  ¹, Hongli Lin  ¹⁶, Yiwen Li  ¹⁷, Qiang He  ¹⁷, Feng Zheng  ¹⁸, Ping Luo  ¹⁹, Gang Long  ²⁰, Wei Lu  ²¹, Kanghui Li  ²², Junwei Yang  ¹, Yingxue Cathy Liu  ²³, Zhizheng Zhang  ²³, Xiaolin Li  ²³, Weifeng Zhang  ²³, Li Zuo  ² （Affiliations ¹ Center for Kidney Disease, Second Affiliated Hospital, Nanjing Medical University, Nanjing, China. ² Department of Nephrology, Peking University People's Hospital, Beijing, China. ³ Nephrology Department, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China. ⁴ Nephrology Department, Shanghai General Hospital, Shanghai, China. ⁵ Nephrology Department, Renmin Hospital of Wuhan University, Wuhan, China. ⁶ Nephrology Department, Shanghai Tenth Hospital, Shanghai, China. ⁷ Nephrology Department, The Second Hospital of Shanxi Medical University, Taiyuan, China. ⁸ Nephrology Department, Affiliated Hospital of Nantong University, Nantong, China. ⁹ Nephrology Department, Changzhou No. 2 People's Hospital, Changzhou, China. ¹⁰ Nephrology Department Jilin Province People's Hospital, Changchun, China. ¹¹ Nephrology Department, Peking University Third Hospital, Beijing, China. ¹² Department of Nephrology, Zhongshan Hospital of Xiamen University School of Medicine, Xiamen, China. ¹³ Nephrology Department, The Third Hospital of Hebei Medical University, Shijiazhuang, China. ¹⁴ Nephrology Department, The Second Affiliated Hospital of Xingtai Medical College, Xingtai, China. ¹⁵ Nephrology Department, Northern Jiangsu People's Hospital, Yangzhou, China. ¹⁶ Nephrology Department, The First Hospital of Dalian Medical University, Dalian, China. ¹⁷ Department of Nephrology, Zhejiang Provincial People's Hospital, Hangzhou, China. ¹⁸ Nephrology Department, The Second Hospital of Dalian Medical University, Dalian, China. ¹⁹ Nephrology Department, The Second Hospital of Jilin University, Changchun, China. ²⁰ Department of Nephrology, Tianjin Union Medical Center, Tianjin, China. ²¹ Department of Nephrology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. ²² Nephrology Department, The Affiliated Hospital of Guilin Medical University, Guilin, China. ²³ Shanghai Alebund Pharmaceuticals Limited, Shanghai, China.）

出处： Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2024

关键词： VS-505;clinical study;hemodialysis;hyperphosphatemia;phosphate binder.

摘要： Background: VS-505 (AP301), an acacia and ferric oxyhydroxide polymer, is a novel fiber-iron-based phosphate binder. This two-part phase 2 study evalu ...

作者： Changling Duan^1,2;Zhongxin Yan^1,2;Cailiang Wu²;Xuexin Zhou²;Wei Bao²CA1 （¹Contributed equally.;²Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 200080, Shanghai, China）

出处： Heliyon 2024

关键词： Methylation;Chemotherapy resistance;Ovarian cancer;DDR2;OPCML

摘要： Objective The high mortality rate of epithelial ovarian cancer (EOC) is often attributed to the frequent development of chemoresistance. DNA methylati ...

作者： Shengzhou Li;Yiming Chen;Xiangqian Cao;Chenkai Yang;Wei Li;Bing Shen （Department of Urology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 200080, Shanghai, China Department of Orthopedics, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 200080, Shanghai, China Department of Urology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 200080, Shanghai, China Department of Urology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 200080, Shanghai, China *Author for correspondence: Department of Nanomedicine & Shanghai Key Lab of Cell Engineering, Naval Medical University, 200433, Shanghai, China **Author for correspondence: Department of Urology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 200080, Shanghai, China Shanghai Tenth People’s Hospital of Tongji University, 200072, Shanghai, China）

出处： Nanomedicine 2024

关键词： graft function evaluation;immunosuppressants;kidney transplantation;nanotechnology;organ preservation

摘要： Kidney transplantation is a crucial treatment option for end-stage renal disease patients, but challenges related to graft function, rejection and imm ...

作者： Sibei Tang¹;Junxun Zhang²;Fangzhou Lou¹;Hong Zhou¹;Xiaojie Cai¹;Zhikai Wang²;Libo Sun¹;Yang Sun¹;Xiangxiao Li¹;Li Fan¹;Yan Li¹;Xinping Jin²;Siyu Deng¹;Qianqian Yin²;Jing Bai¹;Hong Wang²;Honglin Wang¹CA1 （¹Precision Research Center for Refractory Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 201610, Shanghai, China;²Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, 200025, Shanghai, China）

出处： EMBO Reports 2024

关键词： LncRNA Encoded Micropeptide;Autoimmunity;Treg Cell;Dleu2;Smad3

摘要： Micropeptides encoded by short open reading frames (sORFs) within long noncoding RNAs (lncRNAs) are beginning to be discovered and characterized as re ...

作者： Xin He¹CA1;Xiaoying Luo¹2;Yu Wang²3;Jun Zhu³4;Yao Li¹5;Shenmin Zhu¹6;Hui Zhao⁴CA7 （¹Shanghai Jiao Tong University, China;²Shanghai Yuking Water Soluble Tech Co., Ltd., China;³National Engineering Research Center for Nanotechnology, China;⁴Shanghai Jiao Tong University School of Medicine Shanghai General Hospital Department of Ophthalmology, China）

出处： Advanced Nanocomposites 2024

关键词： hydrogel;cholesteric phase;nanoparticles;drug delivery;tumor therapy

摘要： Cellulose nanocrystals (CNCs) are rod-shaped crystalline nanoparticles generated by acidolysis of cellulose, and they exhibit exceptional physical and ...

作者： Yu Wen^1,2;Yibaina Wang^3,2;Renjie Chen¹;Yi Guo¹;Jialu Pu¹;Jianwen Li³CA1;Huixun Jia^1,4CA2;Zhenyu Wu¹CA3 （¹School of Public Health, Key Laboratory of Public Health Safety and Collaborative Innovation Center of Social Risks Governance in Health, Fudan University, Shanghai 200032, China;²These authors have contributed equally to this work.;³China National Center for Food Safety Risk Assessment, Beijing 100022, China;⁴National Clinical Research Center for Ophthalmic Diseases; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai Key Laboratory of Fundus Diseases, Shanghai 200080, China）

出处： Eco-Environment & Health 2024

关键词： Hyperuricemia;Organochlorine pesticide;NHANES;Weighted quantile sum;Quantile g-computation;Bayesian kernel machine regression

摘要： The association between the exposure of organochlorine pesticides (OCPs) and serum uric acid (UA) levels remained uncertain. In this study, to investi ...

作者： Xiaobin Zhu¹;Liu Liu^2,3;Shixiong Tian⁴;Guijun Zhao⁵;Erlei Zhi⁶;Qian Chen¹;Feng Zhang⁷;Aijun Zhang¹CA1;Shuyan Tang^2,4CA2;Chunyu Liu⁷CA3 （¹Department of Gynecology and Obstetrics, Reproductive Medical Center, Shanghai Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 200025, Shanghai, China;²Obstetrics and Gynecology Hospital, Institute of Medical Genetics and Genomics, Fudan University, 200011, Shanghai, China;³Department of Computational Biology, School of Life Science, Fudan University, 200438, Shanghai, China;⁴Human Phenome Institute, Zhangjiang Fudan International Innovation Center, Fudan University, 200438, Shanghai, China;⁵Shanghai Institute of Medical Genetics, Shanghai Children’s Hospital, Shanghai Jiao Tong University School of Medicine, 200040, Shanghai, China;⁶Urologic Medical Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 200940, Shanghai, China;⁷International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, 200030, Shanghai, China）

出处： Molecular Genetics and Genomics 2024

关键词： Male infertility;Asthenoteratospermia;Whole-exome sequencing;FAM71D;ICSI

摘要： Asthenoteratospermia is a significant cause of male infertility. FAM71D (Family with sequence similarity 71, member D), as a novel protein exclusively ...

作者： Mingxing Xia  ¹, Zhenyang Shen  ², Haiming Zheng  ³, Lin Yuan  ⁴, Jiangfeng Hu  ², Yi Zhao  ¹, Dongxun Zhou  ¹, Xianghui Bai  ¹, Junjun Wang  ², Xiaoman Li  ², Weiming Dai  ², Mei Kang  ⁵, Hui Zhou  ², Rong Wan  ², Lungen Lu  ², Bing Hu  ¹, Xinjian Wan  ³, Xiaobo Cai  ² （Affiliations ¹ Department of Gastroenterology and Endoscopy, The Third Affiliated Hospital of Naval Medical University, Shanghai. ² Department of Gastroenterology, Shanghai general Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ Department of Gastroenterology, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai. ⁴ Department of Pathology, Shanghai general Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai. ⁵ Clinical Research Center, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai.）

出处： The American journal of gastroenterology 2024

摘要： Objectives: Although cytologic examination of biliary stricture brushings obtained via endoscopic retrograde cholangiopancreatography (ERCP) is common ...