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作者: Mingjun Ma  1, Jingfen Zhu  2, Yongbin Yang  1, Xiaoyun Wang  1, Yubiao Jin  3, Jiawen Zhang  1   4, Sufang Wu  1 (Affiliations 1 Department of Obstetrics and Gynecology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, P.R. China. 2 School of Public Health, Shanghai Jiao Tong University, Shanghai, P.R. China. 3 Department of Pathology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, P.R. China. 4 Reproductive Medicine Center, Department of Obstetrics and Gynecology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, P.R. China.)

出处: Cancer medicine 2022

关键词: CIN;HPV genotypes;HPV vaccine;cervical lesions;risk factors.

摘要: Human papillomavirus (HPV) infection is the main cause of female precancerous lesions and cervical cancer. The development and application of HPV prop ...

作者: Peng Xu  1, Shaobo Zhang  1, Lili Tan  2, Lei Wang  2, Zhongwei Yang  1, Jinbao Li  1 (Affiliations 1 Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 Department of Anesthesiology, Gansu Provincial Maternity and Child Care Hospital, Lanzhou, China.)

出处: Frontiers in oncology 2022 Vol.12 P836882

关键词: anticancer;drug repurposing;local anesthetics;mechanisms;ropivacaine.

摘要: Despite the significant progress in cancer treatment, new anticancer therapeutics drugs with new structures and/or mechanisms are still in urgent need ...

作者: Yiming Xu #  1   2, Song Xue #  3, Tian Zhang #  4, Xinmeng Jin  1   2, Cong Wang  1, Haiming Lu  1, Yiming Zhong  1   2, Hongjie Chen  1, Libo Zhu  5, Jinzhong Ma  6, Weilin Sang  7 (Affiliations 1 Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 Shanghai Bone Tumor Institution, Shanghai, China. 3 Department of Rheumatology and Immunology, Arthritis Research Institute, The First Affiliated Hospital of Anhui Medical University, Hefei, China. 4 Department of Orthopedics, The Affiliated Yueqing Hospital, Wenzhou Medical University, Wenzhou, China. 5 Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. libozhu2018@163.com. 6 Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. majinzhong1963@sina.com. 7 Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. sangweilin001@163.com.)

出处: Chinese medicine 2022 Vol.17 No.1 P18

关键词: Cartilage;Inflammation;Osteoarthritis;Osteoclastogenesis;Toddalolactone.

摘要: Background: Osteoarthritis (OA) is widely recognized as the most common chronic joint disease accompanied by progressive cartilage and subchondral bon ...

作者: Siteng Chen  1, Encheng Zhang  1, Liren Jiang  2, Tao Wang  1, Tuanjie Guo  1, Feng Gao  2, Ning Zhang  3, Xiang Wang  1, Junhua Zheng  1 (Affiliations 1 Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 Department of Pathology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 3 Department of Urology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.)

出处: Frontiers in immunology 2022 Vol.13 P798471

关键词: F-box family;deep learning;immunotherapy;prognosis;renal cell carcinoma.

摘要: It is of great urgency to explore useful prognostic markers and develop a robust prognostic model for patients with clear-cell renal cell carcinoma (c ...

作者: Lijie Gu  1, Zhifang Wang  2, Yueyue Zhang  1, Nan Zhu  1, Jiayong Li  3, Man Yang  1, Ling Wang  1, Shu Rong  1 (Affiliations 1 Department of Nephrology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 Department of Respiration, Yangpu Hospital, School of Medicine, Tongji University, Shanghai, China. 3 Clinical Laboratory Medicine Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.)

出处: Cell proliferation 2022 Pe13181

关键词: TLR13;chronic kidney disease;insulin resistance;muscle atrophy.

摘要: Objectives: Insulin resistance in chronic kidney disease (CKD) stimulates muscle wasting, but the molecular processes behind the resistance are undete ...

作者: Wen-Yu Liu  1, Jia-Rong Zhang  2, Xian-Ming Xu  1, Tian-Yi Ye  3 (Affiliations 1 Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201600, China. 2 Department of Obstetrics and Gynecology, Zhongshan Hospital, Fudan University, Shanghai 200032, China. 3 Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201600, China. yty1119@sina.com.)

出处: World journal of clinical cases 2022 Vol.10 No.4 P1381-1387

关键词: Case report;Preterm birth;Ritodrine;Side effect;Tocolytics;Toxic epidermal necrolysis.

摘要: Background: Preterm birth accounts for about 12% of all pregnancies worldwide and is the leading cause of neonatal morbidity and mortality. In order t ...

作者: Shujie Wang  1   2, Huahui Ren  3   4, Huanzi Zhong  3, Xinjie Zhao  5, Changkun Li  1   2   6, Jing Ma  6, Xuejiang Gu  7, Yaoming Xue  8, Shan Huang  9, Jialin Yang  10, Li Chen  11, Gang Chen  12, Shen Qu  13, Jun Liang  14, Li Qin  15, Qin Huang  16, Yongde Peng  17, Qi Li  5, Xiaolin Wang  5, Yuanqiang Zou  3, Zhun Shi  3, Xuelin Li  1   2, Tingting Li  1   2, Huanming Yang  3   18, Shenghan Lai  19, Guowang Xu  5, Junhua Li  3, Yifei Zhang  1   2, Yanyun Gu  1   2, Weiqing Wang  1   2 (Affiliations 1 Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the Pr China, Shanghai National Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 3 BGI-Shenzhen, Shenzhen, China. 4 Laboratory of Genomics and Molecular Biomedicine, Department of Biology, University of Copenhagen, Copenhagen, Denmark. 5 Dalian Institute of Chemical Physics, Chinese Academy of Science, Dalian, China. 6 Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 7 Department of Endocrinology, The First Affiliated Hospital of Wenzhou Medical University, Zhejiang Province, China. 8 Nanfang Hospital, Southern Medical University, Guangdong Province, China. 9 Tong Ren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 10 Department of Endocrinology, Central Hospital of Minhang District, Shanghai, China. 11 Department of Endocrinology, Qilu Hospital of Shandong University, Shandong Province, China. 12 Department of Endocrinology, Fujian Provincial Hospital, Fujian Province, China. 13 Department of Endocrinology, Shanghai Tenth People\'s Hospital of Tong Ji University, Shanghai, China. 14 Department of Endocrinology, Xuzhou Central Hospital, Jiangsu Province, China. 15 Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 16 Chang Hai Hospital, Second Military Medical University, Shanghai, China. 17 Shanghai First People\'s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 18 James D. Watson Institute of Genome Sciences, Hangzhou, China. 19 Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.)

出处: Gut microbes 2022 Vol.14 No.1 P2003176

关键词: Type 2 diabetes;berberine;dyslipidemia;gut microbiome;postprandial lipidemia;probiotics.

摘要: Non-fasting lipidemia (nFL), mainly contributed by postprandial lipidemia (PL), has recently been recognized as an important cardiovascular disease (C ...

作者: Nannan Zheng,‡ab  ;Yang Fu,‡cd  ;Xijian Liu, *a  ;Ziwen Zhang,a  ;Jinxia Wang,a  ;Qixiang Mei,cd  ;Xingyan Wang,a  ;Guoying Deng, e  ;Jie Lua  and ;Junqing Hu *bf   (* Corresponding authors a School of Chemistry and Chemical Engineering, Shanghai Engineering Technology Research Center for Pharmaceutical Intelligent Equipment, Shanghai Frontiers Science Research Center for Druggability of Cardiovascular noncoding RNA, Institute for Frontier Medical Technology, Shanghai University of Engineering Science, Shanghai 201620, China E-mail: liuxijian@sues.edu.cn b College of Health Science and Environmental Engineering, Shenzhen Technology University, Shenzhen 518118, China E-mail: hujunqing@sztu.edu.cn c Shanghai Key Laboratory of Pancreatic Disease, Shanghai JiaoTong University School of Medicine, Shanghai 201600, China d Department of Gastroenterology, Shanghai General Hospital, Shanghai JiaoTong University School of Medicine, Shanghai 201600, China e Trauma Center, Shanghai General Hospital, Shanghai JiaoTong University School of Medicine, Shanghai 201620, China f Shenzhen Bay Laboratory, Shenzhen 518132, China)

出处: Journal of Materials Chemistry B 2022

摘要: Chemodynamic therapy (CDT) is an emerging approach to treat cancer based on the tumor microenvironment (TME), but its limited content of endogenous hy ...

作者: Zikai Sun  1   2, Xiaoqiang Liu  1, Yu Liu  2, Xin Zhao  3, Xuan Zang  2, Fang Wang  1 (Affiliations 1 Department of Cardiology, Shanghai General Hospital of Nanjing Medical University, Shanghai, China. 2 Department of Cardiology, The Affiliated Changzhou No.2 People\'s Hospital of Nanjing Medical University, Changzhou, China. 3 Department of Cardiology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.)

出处: Immunopharmacology and immunotoxicology 2022 P1-8

关键词: Dendritic cells;coronary heart disease;dimethyl fumarate;migration.

摘要: Dendritic cells (DCs), as a bridge between innate and adaptive immunity, play key roles in atherogenesis, particularly in plaque rupture, the underlyi ...

作者: Wang, Xing‐Jie1;Ni, Xiao‐Qing2;Zhao, Sheng1;Zhao, Rui‐Zhe3;Wang, Xiao‐Hai1;Xia, Shu‐Jie1;Sun, Xiao‐Wen1;Zhuo, Jian1 (1 Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 2 Department of Dermatology, Song Jiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine 3 Department of Urology, The First Affiliated Hospital of Nanjing Medical University)

出处: Journal of Cellular Physiology 2022 P1

摘要: The sterile inflammation (SI) of the urinary tract is a common problem requiring serious consideration after prostatectomy. This study mainly focuses ...

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