作者： Hanyu Zhang^{1 na1};Jing Xia^{2 na1};Lingling Xie³;Meng Hao⁴;Wenlong Liang¹;Sizhang Wang^2,5;Xiao Dong⁶;Yongxin Li¹ & …Qiang Mu² （¹State Key Laboratory of Bio-Fibers and Eco-Textiles, Institute of Biochemical Engineering, College of Materials Science and Engineering, Qingdao University, Qingdao, 266071, China;²The First Department of Breast Surgery, Qingdao Central Hospital, University of Health and Rehabilitation Sciences (Qingdao Central Hospital), Qingdao, 266042, China;³Brain Science Center Ward, Qingdao Eighth People’s Hospital, Qingdao, 266041, China;⁴Spine Surgery Department, Qingdao Municipal Hospital, Qingdao, 266000, China;⁵Medical College of Qingdao University, Qingdao University, Qingdao, 266071, China;⁶Department of Oncology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 201620, China）

出处： Advanced Composites and Hybrid Materials 2025

关键词： Self-assembly;Cuproptosis;Mitochondria-targeting;Glycolysis;Immunotherapy

摘要： Cuproptosis is an emerging regulated cell death that depends on the intracellular copper ion and mitochondrial respiration, showing great potential in ...

作者： Qian Zhu¹;Xiaoxin Liu¹;Yuan Qu¹;Yan Jiang¹;Xinyi Liu¹;Yu Xiao¹;Kangjia Lv¹;Yupeng Xu²;Kun Liu² （¹Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai, China;Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China;²Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai, China;Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China;Corresponding author.）

出处： The Journal of Nutrition, Health and Aging 2025

关键词： Retina;Diet;Optical coherence tomography;Neurodegeneration;The UK Biobank

摘要： Background: Retinal sublayer thickness is associated with both ophthalmic and neurodegenerative diseases, serving as a valuable biomarker. Despite the ...

作者： Kevin Y. Huang^1,2CA1;Parth A. Patel^1,3;Austin Huang⁴;Allen C. Ho⁵;Jost B. Jonas⁶;Xiaodong Sun⁷;Youxin Chen⁸;Yingfeng Zheng⁹;Yih-Chung Tham^10,11;Christina Y. Weng¹²CA2;Tien Yin Wong^10,13CA3 （¹These authors contributed equally to this work.;²School of Medicine, University of Texas Medical Branch, Galveston, TX, USA;³School of Medicine, Medical College of Georgia, Augusta, GA, USA;⁴School of Medicine, Baylor College of Medicine, Houston, TX, USA;⁵Wills Eye Hospital, Philadelphia, PA, USA;⁶Department of Ophthalmology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany;⁷Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China;⁸Department of Ophthalmology, Peking Union Medical College Hospital, Beijing, China;⁹Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China;¹⁰Singapore Eye Research Institute, Singapore National Eye Center, Singapore;¹¹Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore;¹²Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, TX, USA;¹³Tsinghua Medicine, Tsinghua University, Beijing, China）

出处： Advances in Ophthalmology Practice and Research 2025

作者： Bingxin Li  ¹, Xiaoyun Feng  ¹, Yihan Zhang  ¹, Yunhong Huang  ¹, Mingyu Gu  ¹, Haiyan Sun  ¹, Wenqian Ren  ¹, Qin Zhen  ¹, Tingting Shen  ¹, Ling Pan  ¹, Tingting Fan  ¹, Qin Qin  ¹, Fang Liu  ¹, Yongde Peng  ¹, Yufan Wang  ¹, Huanbai Xu  ¹ （Affiliation ¹ Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghais, China.）

出处： Virulence 2025

关键词： COVID-19;COVID-19 vaccines;Hashimoto Thyroiditis;clinical chemistry tests;hypothyroidism;thyroid function tests.

摘要： The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread rapidly, leading to an Omicron outbreak in Shanghai in mid-December after adju ...

作者： Jingjing Li  ¹, Zhicheng Dai  ², Zhengwei Zhang  ³, Chen Chen  ⁴, Xuehui Xiong  ⁵, Falin Xu  ¹ （Affiliations ¹ Department of Neonatal, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China. ² Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ Department of Pathology, Changzheng Hospital, Naval Medical University, Shanghai, China. ⁴ Department of Psychiatry, School of Mental Health and Psychological Sciences, Anhui Medical University, Hefei, China. ⁵ Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Expert opinion on drug safety 2025

关键词： FAERS;adverse events;disproportionate analysis;gabapentinoids;psychiatric disorders.

摘要： Background: Gabapentinoids, including gabapentin and pregabalin, are commonly used for neuropathic pain but have safety concerns. This study analyzed ...

作者： Huihui Wu¹;Liang Zhu²;Xia Geng³;Xiaona Guo³;Tingting Wang³;Jingjing Xu³;Linkai Jiang³;Weibo Zhang⁴CA （¹a Department of Anesthesiology, Shanghai General Hospital, Shanghai, China;²b Rehabilitation Medicine Center, West China Hospital, Sichuan University, Chengdu, China;³c Department of Pain, Dongying People’s Hospital, Dongying, Shandong, China;⁴d Department of Anesthesiology, Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, Hangzhou, China）

出处： Neurological Research 2025

关键词： Chronic constriction injury;inflammation;Schwann cell;miRNA;target

摘要： Objectives Due to the complex and unclear pathogenesis of neuropathic pain, there is a lack of effective therapeutic strategy. miR-363-5p was consider ...

作者： Siguo Feng  ^{1   2}, Qiuyang Zhang  ^{1   2}, Qing Liu  ^{1   2}, Chang Huang  ³, Huiying Zhang  ^{1   2}, Fengsheng Wang  ^{1   2}, Yue Zhu  ^{1   2}, Qizhi Jian  ⁴, Xue Chen  ⁵, Qin Jiang  ^{1   2}, Biao Yan  ⁴ （Affiliations ¹ The Affiliated Eye Hospital, Nanjing Medical University, Nanjing, China. ² The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, China. ³ Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China. ⁴ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁵ Department of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing, China.）

出处： Diabetes 2025

摘要： Diabetic vasculopathy, encompassing complications such as diabetic retinopathy, represents a significant source of morbidity, with inflammation playin ...

作者： Runzhi Huang ^{#  1   2   3}, Jiaying Shi ^{#  4}, Yifan Liu ^{#  5}, Shuyuan Xian ^{#  2   3}, Wei Zhang ^{#  2   3}, Yuntao Yao  ⁵, Xinru Wu  ⁴, Yuanan Li  ⁴, Haoyu Zhang  ⁴, Bingnan Lu  ⁵, Jiajie Zhou  ⁴, Yibin Zhou  ⁴, Min Lin  ⁶, Xiaonan Wang  ⁷, Xin Liu  ⁸, Yue Wang  ⁹, Wenfang Chen  ¹⁰, Chongyou Zhang  ¹¹, Erbin Du  ¹², Qing Lin  ¹³, Zongqiang Huang  ¹⁴, Yu Chen  ¹⁵, Jie Zhang  ¹⁶, Jun Liu  ¹⁷, Xihui Chen  ¹⁸, Xiuwu Pan  ¹⁹, Xingang Cui  ²⁰, Shizhao Ji  ^{21   22}, Huabin Yin  ²³ （Affiliations ¹ Department of Orthopedics, School of Medicine, Shanghai General Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 100 Haining Road, Shanghai, China. ² Department of Burn Surgery, the First Affiliated Hospital of Naval Medical University, Shanghai, People's Republic of China. ³ Research Unit of key techniques for treatment of burns and combined burns and trauma injury, Chinese Academy of Medical Sciences, Shanghai, People's Republic of China. ⁴ Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. ⁵ Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China. ⁶ Mental Health Education and Consultation Center, Chongqing Medical University, 61 Daxuecheng Middle Road, Chongqing, 401331, China. linmin_513@163.com. ⁷ Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing, 100069, China. hnaywxn@163.com. ⁸ Department of Rheumatology and Immunology, Second Affiliated Hospital of Naval Medical University, Shanghai, China. lxsmmu@163.com. ⁹ Department of Health Statistics, School of Public Health, Air Force Medical University, Xi'an, 710032, China. wangyuek11@126.com. ¹⁰ Faculty of Medicine, Jinggangshan University, Ji'An, 343009, China. 9919970039@jgs.edu.cn. ¹¹ Basic Medical College, Harbin Medical University, Heilongjiang, 150081, China. cyzhanghmu@sina.com. ¹² Frist Clinical Medical College, Mudanjiang Medical University, Mudanjiang, 157011, China. 1748855216@qq.com. ¹³ Department of Human Anatomy, Laboratory of Clinical Applied Anatomy, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, 350122, China. linqing522@126.com. ¹⁴ Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. gzhuangzq@163.com. ¹⁵ Department of Gynecology and Obstetrics, The First Affiliated Hospital of Naval Medical University, Yangpu District, No. 168 Changhai Road, Shanghai, 200433, China. yueryw@163.com. ¹⁶ Department of Gynecology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, 201204, China. jiezhang@tongji.edu.cn. ¹⁷ Department of Anesthesiology, Shanghai Pulmonary Hospital Affiliated to Tongji University, 507 Zheng Min Road, Shanghai, 200433, China. yirong007@126.com. ¹⁸ Clinical Education Centre, the, First Affiliated Hospital , PLA Naval Medical University, Shanghai, 200433, China. cxh840808@126.com. ¹⁹ Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China. panxiuwu@126.com. ²⁰ Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China. cuixingang@xinhuamed.com.cn. ²¹ Department of Burn Surgery, the First Affiliated Hospital of Naval Medical University, Shanghai, People's Republic of China. shizhaoji2022@163.com. ²² Research Unit of key techniques for treatment of burns and combined burns and trauma injury, Chinese Academy of Medical Sciences, Shanghai, People's Republic of China. shizhaoji2022@163.com. ²³ Department of Orthopedics, School of Medicine, Shanghai General Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 100 Haining Road, Shanghai, China. yinhuabin@aliyun.com.）

出处： BMC psychology 2025

关键词： Empathy;Jefferson Scale of Empathy (JSE);Learning environment (LE);Medical students.

摘要： Background: Empathy of medical students is crucial, yet it tends to decline as students enter later academic years. Empathy appeared to be affected by ...

作者： Fei Wang¹;Ming Ju¹;Xianxun Zhu¹;Qiuyu Zhu¹;Haiquan Wang²;Chunhua Qian³ & …Rui Wang¹ （¹School of Communication and Information Engineering, Shanghai University, No. 99 Shangda Rd., Shanghai, 200444, China;²Department of General Surgery, Shanghai General Hospital of Shanghai Jiaotong University, No. 100 Haining Rd., Shanghai, 200080, China;³Department of Endocrinology and Metabolism, Shanghai Tenth People’s Hospital, Tongji University, School of Medicine, No. 301 Middle Yanchang Rd., Shanghai, 200072, China）

出处： The Journal of Supercomputing 2025

关键词： Skin lesion;Geometric algebra;Residual networks;Detection system

摘要： Automatic intelligent skin lesion recognition is crucial for elevating detection accuracy, enhancing diagnostic efficiency, and mitigating the risk of ...

作者： Jingdong Xue¹;Siang Lv^2,3,4;Ming Yu¹;Yixuan Pan¹;Ningzhe Li^1,5;Xiang Xu⁶;Qi Zhang¹;Mengyuan Peng¹;Fang Liu¹;Xuxu Sun¹;Yimin Lao¹;Yanhua Yao¹;Juan Song¹;Jun Wu^6,3,4CA;Bing Li¹CA （¹Department of Biochemistry and Molecular Cell Biology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Key Laboratory for Tumor Microenvironment and Inflammation, Shanghai Jiao Tong University School of Medicine , Shanghai 200025 , China;²Department of Laboratory Medicine, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai 201803 , China;³Clinicopathological Diagnosis & Research Center, The Affiliated Hospital of Youjiang Medical University for Nationalities , Baise 533000 , China;⁴Key Laboratory of Tumor Molecular Pathology of Guangxi Higher Education Institutes , Baise 533000 , China;⁵Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University , Shanghai 200025 , China;⁶Department of Laboratory Medicine, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai 201803, China）

出处： Protein & Cell 2025