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作者: Kepeng Ou  1, Youjian Li  1, Ling Liu  2, Hua Li  2, Katherine Cox  3, Jiahui Wu  4, Jian Liu  3, Andrew D Dick  5 (Affiliations 1 College of Pharmacy, National & Local Joint Engineering Research Center of Targeted and Innovative Therapeutics, IATTI, Chongqing University of Arts and Sciences, Chongqing, China; Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. 2 Department of Ophthalmology, Yongchuan Hospital, Chongqing Medical University, Chongqing, China. 3 Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. 4 Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People\'s Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China. 5 Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol; Institute of Ophthalmology, University College London, London; National Institute for Health Research Biomedical Research Centre, Moorfields Eye Hospital, London, UK.)

出处: Neural regeneration research 2022 Vol.17 No.9 P1919-1928

关键词: antioxidants;autophagy enhancers;complement inhibitors;exosomes;neuropeptides;neuroprotective agents;retinal degeneration;senolytics.

摘要: Retinal degeneration is a debilitating ocular complication characterized by the progressive loss of photoreceptors and other retinal neurons, which ar ...

作者: Shu Yang  1, Bing-Cheng Wu  1, Zhe Cheng  2, Lan Li  3, Yuan-Ping Zhang  4, Hui Zhao  5, Han-Mei Zeng  1, Dong-Fang Qi  1, Zi-Yao Ma  1, Jian-Guo Li  1, Rui Han  1, Fang-Zhou Qu  1, Yan Luo  6, Yi Liu  7, Xiao-Lei Chen  8, Hong-Mei Dai  1 (Affiliations 1 Department of Ophthalmology, The First Hospital of Kunming, Kunming, 650011 Yunnan Province, China. 2 Eye institute of Xiamen University, Xiamen, Fujian, China. 3 Department of Ophthalmology, The Calmette Affiliated Hospital of Kunming Medical University, Kunming, China. 4 Department of Ophthalmology, The Second Affiliated Hospital of Kunming Medical University, Kunming, China. 5 Department of Ophthalmology, Shanghai General Hospital (Shanghai First People\'s Hospital), Shanghai 200080, China. 6 Department of Pediatrics, The First Hospital of Kunming, Kunming, 650011 Yunnan Province, China. 7 Department of Otorhinolaryngology, The First Hospital of Kunming, Kunming, 650011 Yunnan Province, China. 8 Department of Endocrinology, The First Hospital of Kunming, Kunming, 650011 Yunnan Province, China.)

出处: Disease markers 2022 Vol.2022 P7550090

摘要: Objective: The aims of our experiment were to compare the microorganisms in meibomian gland secretions from patients with internal hordeolum before an ...

作者: Yifan Zhou  1, Yanping Hu  2, Jianfeng Luo  3, Yinwen Li  4   5   6, Haiyun Liu  4   5   6, Xiaodong Sun  4   5   6, Minwen Zhou  4   5   6 (Affiliations 1 Department of Ophthalmology, Putuo People\'s Hospital, Tongji University, Shanghai, China. 2 Shanghai Putuo Center for Disease Control and Prevention, Shanghai, China. 3 School of Public Health, Fudan University, Shanghai, China. 4 Department of Ophthalmology, Shanghai General Hospital (Shanghai First People\'s Hospital), School of Medicine, Shanghai Jiao Tong University, Shanghai, China. 5 National Clinical Research Center for Eye Diseases, Shanghai, China. 6 Shanghai Key Laboratory of Fundus Diseases, Shanghai, China.)

出处: Frontiers in medicine 2022 Vol.8 P810159

关键词: CHARLS;dual sensory loss;falls;hearing loss;vision loss.

摘要: Introduction: Previous studies have suggested that sensory loss is linked to falls. However, most of these studies were cross-sectional designed, focu ...

作者: Lijun Tang  1, Xiao Zhao  2, Shitong Li  2, Lina Huang  2, Jinbao Li  2, Lianhua Chen  1, Shiwei Huang  2 (Affiliations 1 Department of Anesthesiology, Shanghai General Hospital of Nanjing Medical University, Shanghai, China. 2 Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China.)

出处: Frontiers in medicine 2022 Vol.9 P717477

关键词: apnea duration;oxygen saturation;rapid sequence induction intubation;rocuronium;succinylcholine.

摘要: Objective: The present study aimed to evaluate the impact of 1.5 mg/kg succinylcholine or 1.2 mg/kg rocuronium, vs. 1.0 mg/kg succinylcholine on apnea ...

作者: Tang, Gang1;Du, Yi1;Guan, Haochen1;Jia, Jieshuang1;Zhu, Nan1;Shi, Yuping1;Rong, Shu1;Yuan, Weijie1 (1 Department of Nephrology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China)

出处: British Journal of Pharmacology 2022 Vol.179 No.1 P159-178

关键词: butyrate;db/db mice;diabetic nephropathy;FFA2;muscle atrophy

摘要: Background and Purpose: Muscle protein catabolism in patients with diabetic nephropathy (DN) results in striking loss of muscle proteins, which increa ...

作者: Dong Lin  1, Liang Wu  1, Jiang Fan  1 (Affiliation 1 Department of Thoracic Surgery, Shanghai General Hospital Shanghai Jiao Tong University School of Medicine, Shanghai, China.)

出处: JAMA surgery 2022

作者: Yingying Sun  1, Jie Jin  2, Aying Zhu  1, Hong Hu  1, Yingying Lu  1, Yue Zeng  1, Dadao Jing  1 (Affiliations 1 Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201600, People\'s Republic of China. 2 Department of Geriatrics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, People\'s Republic of China.)

出处: International journal of general medicine 2022 Vol.15 P1319-1328

关键词: first episode pancreatitis;infected pancreatic necrosis;low-density lipoprotein cholesterol;recurrent acute pancreatitis;risk factors.

摘要: Background: In recent years, the cure rate of acute pancreatitis (AP) has increased gradually, but the morbidity of recurrent acute pancreatitis (RAP) ...

作者: Xiao Shen  1   2, Guorong Fan  1, Gaolin Liu  1, Fan Wang  3, Qi Li  3, Xinyan Liu  2, Hong Zhu  2, Ying Zhu  2, Jiguang Lu  2, Shuowen Wang  1 (Affiliations 1 Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai. 2 Department of Pharmacy, Suzhou Kowloon Hospital, Shanghai Jiaotong University School of Medicine, Suzhou, Jiangsu Province. 3 Department of Oncology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China.)

出处: Anti-cancer drugs 2022 Vol.33 No.1 Pe802-e807

摘要: The incidence of lung cancer is increasing yearly worldwide, and targeted medicines are the main choice for lung cancer patients. However, there has b ...

作者: Weijun Shen1;Xuan Zhao2;Shitong Li1,3CA1 (1 Nanjing Medical University, Shanghai General Hospital, 200080, Shanghai, China; 2 Department of Anesthesiology, Tenth People’s Hospital of Tongji University, No 301 Middle Yan Chang Road, 200072, Shanghai, China; 3 Nanjing Medical University, Shanghai General Hospital, 200080, Shanghai, China)

出处: Inflammation 2022 Vol.45 No.1 P331-342

关键词: exosomes;sepsis;lung injury;circ-fryl;SIRT3.

摘要: Sepsis-induced lung injury is a clinical syndrome characterized by injury of alveolar epithelium cells (AECs). Previous investigations illustrate that ...

作者: Yongyi Xie #  1, Baoyi Liu #  1, Zhouwei Wu  1 (Affiliation 1 Department of Dermatology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, People\'s Republic of China.)

出处: Clinical, cosmetic and investigational dermatology 2022 Vol.15 P77-86

关键词: biomarker;metabolism;systemic lupus erythematosus.

摘要: Purpose: Skin involvement is the second most common symptom of systemic lupus erythematosus (SLE), and the prevention of skin lesion development might ...

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