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作者: Jia-Yu Peng1,2,3,4;Xiao Fu1,4;Xue-Yang Luo1;Fang Liu5;Bing Zhang1;Bin Zhou6;Kun Sun2CA1;Alex F. Chen1CA21Institute for Developmental and Regenerative Cardiovascular Medicine, Xin Hua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China;2Department of Pediatric Cardiology, Xin Hua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China;3Department of Child Healthcare, The International Peace Maternity & Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China;4Jia-Yu Peng and Xiao Fu contributed equally.;5Department of Endocrinology and Metabolism, Shanghai General Hospital Affiliated to Shanghai Jiao Tong University, School of Medicine, Shanghai, China;6New Cornerstone Investigator Institute, State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai, China)

出处: Translational Research 2024

摘要: Background Post-ischemic angiogenesis is critical for perfusion recovery and tissue repair. ELABELA (ELA) plays an essential role in embryonic heart d ...

作者: Wentong Mei1,2;Xiuli Zhang3,4,5,2;Mengya Niu6;Liang Li6;Xiaoyu Guo4,5,6,7;Gang Wang7;Stephen Pandol8;Li Wen4,5CA1;Feng Cao1CA21Department of General Surgery, Xuanwu Hospital Capital Medical University, Beijing 100053, China;2WM and XZ are co-first authors.;3Center for Biomarker Discovery and Validation, National Infrastructures for Translational Medicine (PUMCH), Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, 100730, China;4State Key Laboratory of Complex, Severe, and Rare Diseases, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China;5Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, 100730, China;6Department of Gastroenterology and Shanghai Key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201600, China;7Department of Pancreatic and Biliary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China;8Department of Medicine, Cedars-Sinai Medical Center, Los Angel, CA, 90048, USA)

出处: Pancreatology 2024

摘要: Background Store-operated Ca2+ entry (SOCE) mediated by ORAI1 channel plays a crucial role in acute pancreatitis (AP). Macrophage is an imp ...

作者: Mo Cheng  1, Qingjie Kong  2, Qing Tian  3, Weiluo Cai  1, Chunmeng Wang  1, Minjia Yuan  4   5, Wenxing Wang  6, Peiyuan Wang  7, Wangjun Yan  8 (Affiliations 1 Department of Musculoskeletal Surgery of Shanghai Cancer Center, Fudan University, Shanghai, 200032, P. R. China. 2 Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, P. R. China. 3 Department of Neurology, Qingpu Branch of Zhongshan Hospital, Fudan University, Shanghai, 201799, P. R. China. 4 Department of Chemistry, iChEM (Collaborative Innovation Center of Chemistry for Energy Materials), Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, State Key Laboratory of Molecular Engineering of Polymers, Laboratory of Advanced Materials, Fudan University, Shanghai, 200433, P. R. China. 5 Shanghai Qiran Biotechnology Co., Ltd, Shanghai, 201702, China. 6 Department of Chemistry, iChEM (Collaborative Innovation Center of Chemistry for Energy Materials), Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, State Key Laboratory of Molecular Engineering of Polymers, Laboratory of Advanced Materials, Fudan University, Shanghai, 200433, P. R. China. wangwenxing@fudan.edu.cn. 7 Key Laboratory of Design and Assembly of Functional Nanostructures, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, 350002, P. R. China. wangpeiyuan@fjirsm.ac.cn. 8 Department of Musculoskeletal Surgery of Shanghai Cancer Center, Fudan University, Shanghai, 200032, P. R. China. yanwj@fudan.edu.cn.)

出处: Journal of nanobiotechnology 2024

摘要: Background: As the lethal bone tumor, osteosarcoma often frequently occurs in children and adolescents with locally destructive and high metastasis. D ...

作者: Yanrui Jin1;Zhiyuan Li1;Chengjin Qin1CA1;Jinlei Liu1;Yunqing Liu1;Liqun Zhao2;Chengliang Liu1CA21State Key Laboratory of Mechanical System and Vibration, School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China;2Department of Cardiology, Shanghai First People’s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai 200080, China)

出处: Biomedical Signal Processing and Control 2023

关键词: Attention mechanism;Convolution neural network;ECG quality assessment;Long short-term memory neural network

摘要: ECG quality assessment is of great significance to reduce false alarms in automatic arrhythmia and other cardiovascular diseases diagnoses and reduce ...

作者: Lei Tang  1, Guo-Tong Xu  1, Jing-Fa Zhang  2 (Affiliations 1 Department of Ophthalmology of Tongji Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China. 2 Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University; National Clinical Research Center for Eye Diseases; Shanghai Key Laboratory of Ocular Fundus Diseases; Shanghai Engineering Center for Visual Science and Photomedicine; Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China.)

出处: Neural regeneration research 2023

关键词: Müller cells;anti-inflammation therapy;anti-vascular endothelial growth factor;diabetic retinopathy;hyperreflectivity foci;inflammation;inflammatory cells;inflammatory cytokines;leukostasis;microglia.

摘要: Diabetic retinopathy, characterized as a microangiopathy and neurodegenerative disease, is the leading cause of visual impairment in diabetic patients ...

作者: Chao Zhong1,2;Yueming Wu1,2;Haodong Lin3,4CA1;Runhui Liu1,5,6CA21State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, 200237, China;2C. Z. and Y. W. have equally contributed to the manuscript.;3Department of Orthopedic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China;4Jiading Branch of Shanghai General Hospital, Shanghai, 201803, China;5Frontiers Science Center for Materiobiology and Dynamic Chemistry, Shanghai Frontier Science Research Base of Optogenetic Techniques for Cell Metabolism, Research Center for Biomedical Materials of Ministry of Education, Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai, 200237, China;6East China University of Science and Technology Shenzhen Research Institute, Shenzhen 518063, China)

出处: Composites Part B: Engineering 2023

摘要: Osteomyelitis is a major complication of orthopedic diseases with high recurrence and morbidity, along with long hospital stays and high medical costs ...

作者: Chong Chen  1, Guangyi Hu, Feng'e Chen, Kun Liu, Suqin Yu, Xun Xu (Affiliation 1 Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China.)

出处: Retina (Philadelphia, Pa.) 2023

摘要: Carbon fiber microelectrodes and carbon fiber composite minielectrodes (CFM/CFCM) have been generally used for measurements of nitric oxide (NO) conce ...

作者: Yifan Zhou;Jin Wei;Qinglei Sun;Haiyun Liu;Ye Liu;Jianfeng Luo;Minwen Zhou (Affiliations 1 Department of Ophthalmology, Putuo People's Hospital, Tongji University, Shanghai 200060, China. 2 Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), School of Medicine, Shanghai JiaoTong University, Shanghai 200080, China. 3 National Clinical Research Center for Eye Diseases, Shanghai 200080, China. 4 Department of Ophthalmology, Shanghai East Hospital, Shanghai 200120, China. 5 Department of Biostatistics, School of Public Health, Fudan University, Shanghai 200032, China. 6 NHC Key Laboratory of Health Technology Assessment, Fudan University, Shanghai 200032, China. 7 Key Laboratory of Public Health Safety of Ministry of Education, Fudan University, Shanghai 200032, China.)

出处: Journal of clinical medicine 2023

关键词: China Health and Retirement Longitudinal Study;cognitive decline;hearing;sensory impairment;vision.

摘要: Previous studies on longitudinal sensory-cognition association are limited and have yielded inconsistent conclusions in western and developed countrie ...

作者: Meirong Yu;Shuang Wu;Chao Gong;Lianhua Chen (Affiliation 1 Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.)

出处: Frontiers in pharmacology 2023

关键词: C2C12 myotubes;GLUT4 translocation;Neuregulin-1β;PI3K/AKT;glucose uptake.

摘要: Insulin resistance (IR) is a feature of type 2 diabetes (T2DM) accompanied by reduced glucose uptake and glucose transporter 4 (GLUT4) translocation b ...

作者: Yinuo Wang;Junyao Zhang;Yingying Zhang;Junyan Yao (Affiliation 1 Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.)

出处: Frontiers in endocrinology 2023

关键词: Citespace;Ketogenic Diet;Neurological Diseases;Neuroprotection;Oxidative Stress;VOSviewer;bibliometric analysis;hotspots.

摘要: Background: The protective effects of Ketogenic Diet Therapies (KDTs) on neurological diseases have been extensively studied over the past two decades ...

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