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作者: Fang Fang1;Rui Tai2;Fu Yang2;Ran Dong2;Yaqing Zhang1,3CA11School of Nursing, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China;2Department of Nursing, Shanghai General Hospital, Shanghai, 200080, China;3ORCID: 0009-0000-6019-0844)

出处: Current Pharmaceutical Analysis 2025

关键词: Gastrointestinal stromal tumor;bioinformatic analysis;drug resistance;metastasis;diagnostic biomarker;immune cell infiltration

摘要: Background Gastrointestinal stromal tumor (GIST) is a prevalent neoplasm in digestive tract, drug resistance and metastasis remain the major challenge ...

作者: Mengqi Zhao1,2;Mengyan Cui1,2;Miaoyan Fan1,2;Chunlan Huang2;Jingjing Wang1;Yue Zeng2;Xingpeng Wang2CA1;Yingying Lu2CA21Shanghai Key Laboratory of Pancreatic Disease, Shanghai Jiaotong University School of Medicine, Shanghai, 201620, China;2Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 201620, China)

出处: European Journal of Pharmacology 2025

关键词: octreotide;acute pancreatitis;intestinal microbiota;pyroptosis;intestinal barrier

摘要: Severe acute pancreatitis (SAP) is a common clinical condition characterized by acute abdominal symptoms. Octreotide (OCT) is a commonly prescribed tr ...

作者: Pengfei Yang1,2;Fu Yang2;Qi Wang3;Fang Fang1,2CA1;Qian Yu2;Rui Tai21School of Nursing, Shanghai Jiao Tong University School of Medicine, Shanghai, China;2Department of Nursing, Shanghai General Hospital, Shanghai, China;3School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China)

出处: International Journal of Nursing Sciences 2025

关键词: Critical care;Post-intensive care syndrome;Prediction model;Systematic review

摘要: Objectives This systematic review aimed to assess the properties and feasibility of existing risk prediction models for post-intensive care syndrome o ...

作者: Wenqi Pan1;Sihui Shao1;Xinyue Cao2;Xinyue Dai2;Yi Zheng1;Jingyun Cheng1;Wei Feng2CA1;Rong Wu1CA2;Yu Chen2CA31Department of Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 200080 Shanghai, P. R. China;2Materdicine Lab, School of Life Sciences, Shanghai University, 200444 Shanghai, P. R. China)

出处: Journal of the American Chemical Society 2025

摘要: The presence of a substantial necrotic core in atherosclerotic plaques markedly heightens the risk of rupture, a consequence of elevated iron levels t ...

作者: Libin Song1,2,3CA1;Yu Zeng4,3;Chuanfang Pan1,2;Jing Xie1,2;Xiumei Zhang1,2;Jiling Feng4CA2;Shengli Li4CA31Department of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai, 200032, China;2Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China;3These authors contributed equally to this work.;4Precision Research Center for Refractory Diseases and Shanghai Key Laboratory of Pancreatic Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China)

出处: Pharmacological Research - Modern Chinese Medicine 2025

关键词: Pancreatic cancer;Chinese herbal medicine;Qingyihuaji formula;Patient survival

摘要: Introduction Pancreatic cancer (PC) is recognized for its aggressive nature and poor prognosis. Despite advancements in therapeutic approaches, the su ...

作者: Min Wang1;Zhaohui Huang1;Yonghong Zhu2;Xin Li3;He Sun4;QiuLing Fan1,5CA11Department of Nephrology, The First Hospital of China Medical University, Shenyang, Liaoning, China;2Department of Nephrology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China;3Department of Nephrology, The Fourth Affiliated Hospital of China Medical University, Shenyang, Liaoning, China;4Department of Endocrinology, Shengjing Hospital of China Medical University, Shenyang, China;5Department of Nephrology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China)

出处: Kidney International Reports 2025

关键词: apabetalone;cholesterol accumulation;diabetic kidney disease;gut microbiota

摘要: Introduction A US Food and Drug Administration–approved new bromodomain (BRD) and extraterminal (BET) bromine domain antagonist called apabetalone, wh ...

作者: Ningning Song1;Xinquan Xi1;Kuan Yang2CA1;Chongzhe Pei2CA2;Lingzhou Zhao3CA31Department of Breast Surgery, Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Shushan District, Hefei, Anhui 230022, PR China;2Department of Cardiology, Tianjin Medical University General Hospital, 154 Anshan Road, Heping, Tianjin 300052, PR China;3Department of Nuclear Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, PR China)

出处: Ecotoxicology and Environmental Safety 2025

关键词: EDCs;Blood Metabolome;Epigenetics;Breast cancer;Mendelian Randomization

摘要: Current research on the relationship between environmental endocrine disrupting chemicals (EDCs) and breast cancer remains insufficient, with limited ...

作者: Yilin Pan1,2;Kaijun Chen3,2;Wen Hua3,2;Li Yu4,2;Wuping Bao1;Cuiqin Shi4;Huahao Shen3CA1;Zhihua Chen3CA2;Min Zhang1CA31Department of Pulmonary and Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;2Yilin Pan, Kaijun Chen, Wen Hua and Li Yu contributed equally to this work.;3Department of Respiratory and Critical Care Medicine, the 2nd Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China;4Department of Pulmonary and Critical Care Medicine, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China)

出处: Phytomedicine 2025

关键词: Asthma;Suhuang Zhike capsules;Randomized controlled trial;Adult;Cough

摘要: Background Suhuang Zhike Capsules (SHZK) are a traditional Chinese medicine formulation that are widely used to treat post-infectious cough. However, ...

作者: Meixuan Liu1;Hongmei Xu1,2CA1;Yunxuan Gu1;Jianhong Zhu3;Hongai Zhang4;Hongwei Lu3;Jian Sun1;Zhenxing Shen1,2;Junji Cao21Department of Environmental Science and Engineering, Xi’an Jiaotong University, Xi’an 710049, China;2SKLLQG, Key Lab of Aerosol Chemistry & Physics, Institute of Earth Environment, Chinese Academy of Sciences, Xi’an 710061, China;3Second Affiliated Hospital of Medical College, Xi’an Jiaotong University, Xi’an 710004, China;4Department of Neonatology, Shanghai General Hospital Affiliated To Shanghai Jiao Tong University School Of Medicine, Shanghai 201620, China)

出处: Environment & Health 2025

关键词: solid fuel combustion;personal exposure;biomarker;blood pressure;mediating effect

摘要: High Resolution Image Download MS PowerPoint Slide Rural households in northwest China rely on solid fuels as their main heating energy source in wint ...

作者: Jing Wang1,2,3;Yifang Huang1,2,3;Qiuli Zhu4,3;Chen Huang2;Ruilang Lin2;Yuwei Peng2;Zixuan Jiang1,2;Dongxu Tang5;Ye Yao2;Xueying Zheng2CA1;Guoyou Qin1,2CA2;Jiaohua Chen5CA31Shanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai 200032 China;2Department of Biostatistics, NHC Key Laboratory for Health Technology Assessment, Key Laboratory of Public Health Safety of Ministry of Education, School of Public Health, Fudan University, Shanghai 200032 China;3The three authors contribute equally to this work.;4Healthcare-associated Infection Prevention and Control Office, Shanghai General Hospital, Address: No. 100 Haining Road, Hongkou District, Shanghai, China;5Department of Health Management, Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China)

出处: Brain, Behavior, and Immunity 2025

摘要: Background Previous evidence suggests that infectious diseases may contribute to the development of neurodegenerative diseases (NDDs) while individual ...

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