作者： Xiao, Fangjie^a;Xia, Yan^bCAa （^aChest Surgery, Jiaozhou Central Hospital of Qingdao, Shandong, Jiaozhou, 266300, China;^bPathological Center, Shanghai General Hospital, Shanghai, 200080, China）

出处： Heart Surgery Forum 2024

关键词： inflammatory indices;primary spontaneous pneumothorax;spontaneous respiration anaesthesia;thoracoscopic surgery

摘要： Background: In thoracoscopic surgery under spontaneous respiration, patients could breathe spontaneously during surgery without the need for mechanica ...

作者： Sun, Zhongshang^a,b,c,d;Guo, Yuecheng^c,d;Xu, Xianjun^c,d;Zhou, Cui^c,d;Luo, Xin^c,d;Shen, Zhenyang^c,d;Shen, Bo^c,d;Wang, Junjun^c,d;Lu, Jingyi^c,d;Zhang, Qingqing^c,d;Shen, Feifei^e;Yu, Lou^c;Ye, Yanping^f;Zhang, Ling^f;Luo, Ying^f;Qu, Ying^c,d;Cai, Xiaobo^c,dCAa;Dong, Hui^c,dCAb;Lu, Lungen^a,c,dCAc （^aDepartment of Gastroenterology, Shanghai General Hospital of Nanjing Medical University, Shanghai, China;^bDepartment of Gastroenterology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huai'an, China;^cDepartment of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;^dShanghai Key Laboratory of Pancreatic Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, China;^eDepartment of Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;^fContinent Pharmaceuticals Co., Ltd, Beijing, China）

出处： Journal of Gastroenterology and Hepatology (Australia) 2024

关键词： apoptosis;endoplasmic reticular stress;hepatic stellate cell;hydronidone;mitochondrial apoptotic pathway

摘要： Background and Aim: Hydronidone (HDD) is a novel pirfenidone derivative developed initially to reduce hepatotoxicity. Our previous studies in animals ...

作者： Yang, Jiaying^a;Lai, Mengyu^a;Ma, Yuhang^a;Wu, Jingzhu^a;Zhang, Chuan^b;Yuan, Huiwen^b;Liang, Guiling^a;Meng, Chuchen^a;Su, Yanmei^a;Luan, Bing^bCAa;Gu, Liping^aCAb;Wang, Yufan^aCAc （^aDepartment of Endocrinology and Metabolism, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;^bDepartment of Endocrinology, Tongji Hospital Affiliated to Tongji University School of Medicine, Tongji University, Shanghai, China）

出处： Chemical Engineering Journal 2024

关键词： Composite hydrogel;Diabetic wound healing;Immune microenvironment;Macrophage polarization;Tissue remodelling

摘要： Uncontrolled programmed polarization of macrophages plays an important role in chronic diabetic wound healing. Therefore, correcting programmed macrop ...

作者： Zhao, Yucui^a,b;He, Sijia^a;Zhao, Minghui^a,c;Huang, Qian^a,dCAa （^aCancer Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China;^bDepartment of Radiation Oncology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, China;^cDepartment of Radiation Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China;^dShanghai Key Laboratory of Pancreatic Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China）

出处： Advanced Science 2024

关键词： cancer resistance;cytotoxic therapy;depolyploidization;polyaneuploid giant cancer cells;polyploidization

摘要： Polyploidization and depolyploidization are critical processes in the normal development and tissue homeostasis of diploid organisms. Recent investiga ...

作者： Wang, Zi-Hao^a;Wang, Jingyi^b,c;Liu, Fuchen^d;Sun, Sijun^b,e;Zheng, Quan^f;Hu, Xiaotian^e;Yin, Zihan^b,c;Xie, Chengmei^b;Wang, Haiyan^c;Wang, Tianshi^gCAa;Zhang, Shengjie^bCAb;Wang, Yi-Ping^a,bCAc （^aInstitutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, China;^bPrecision Research Center for Refractory Diseases, Institute for Clinical Research, Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, China;^cDepartment of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, China;^dThe Third Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, Third Affiliated Hospital, Naval Medical University, Shanghai, China;^eDepartment of Gastrointestinal Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, China;^fCenter for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, China;^gDepartment of Biochemistry and Molecular Cell Biology, Shanghai Jiao Tong University School of Medicine, China）

出处： FEBS Letters 2024

关键词： histone H3 lysine 4 tri-methylation;liver cancer;mitochondrial respiration;oxidative phosphorylation;SET and MYND domain-containing protein 3;THAP domain-containing 3

摘要： Mitochondria harbor the oxidative phosphorylation (OXPHOS) system to sustain cellular respiration. However, the transcriptional regulation of OXPHOS r ...

作者： Zhou, Zheng^a;Hu, Jianhai^a;Zhu, Min^a;Yu, Jianing^a;Liu, Wei^b;Xu, Sudan^cCAa;Wu, Peng^bCAb （^aMedical School, Anhui University of Science and Technology, Anhui, Huainan, China;^bDepartment of Orthopedics, Tongji University Tenth People’s Hospital, Shanghai Tenth People’s Hospital, Shanghai, China;^cDepartment of Cardiology, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, China）

出处： Medical Science Monitor 2024

关键词： Arthroscopy;Knee;Methylene Blue;Osteoarthritis;Popliteal Cyst

摘要： Background: This retrospective study of 42 patients with popliteal cysts (or Baker cysts) aimed to compare the effects on duration and outcomes of art ...

作者： Zhang, Lei^a;Sun, Yiwu^b;Sui, Xin^a;Zhang, Jian^a;Zhao, Jingshun^a;Zhou, Runfeng^a;Xu, Wenjia^a;Yin, Chengke^a;He, Zhaoyi^a;Sun, Yufei^a;Liu, Chang^a;Song, Ailing^c;Han, Fei^aCAa （^aDepartment of Anesthesiology, Harbin Medical University Cancer Hospital, Harbin, China;^bDepartment of Anesthesiology, Dazhou Central Hospital, Dazhou, China;^cDepartment of Anesthesiology, Shanghai Jiao Tong University First People's Hospital (Shanghai General Hospital), Shanghai, China）

出处： ESC Heart Failure 2024

关键词： Acute heart failure;Arterial blood gas;Medical Information Mart for Intensive Care IV;Partial pressure of arterial carbon dioxide

摘要： Aims: Both hypercapnia and hypocapnia are common in patients with acute heart failure (AHF), but the association between partial pressure of arterial ...

作者： Wu, Mingwei^a;Zeng, Zhaoxiang^b;Bao, Xianhao^b;Ren, Luxia^a;Feng, Jiaxuan^b;Feng, Rui^c;Xiong, Jiang^aCAa （^aDepartment of Vascular and Endovascular Surgery, Chinese People’s Liberation Army General Hospital, Beijing, China;^bDepartment of Vascular Surgery, Changhai Hospital, Navy Medical University, Shanghai, China;^cDepartment of Vascular Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China）

出处： Journal of Endovascular Therapy 2024

关键词： blunt thoracic aortic injury;endograft;long-term;multi-center study;thoracic endovascular aneurysm repair

摘要： Objective: This study aimed to assess the long-term outcomes in patients treated by thoracic endovascular aortic repair (TEVAR) for blunt thoracic aor ...

作者： Du, Wei^a;Li, Ying^a;Wang, Xufeng^a;Xie, Sunzhe^a;Ci, Hongfei^a;Zhou, Jiaming^a;Zhu, Ningqi^a;Chen, Zule^a;Zheng, Yan^bCAa;Jia, Huliang^a,cCAb （^aHepatobiliary Surgery, Department of General Surgery, Huashan Hospital, Fudan University, Shanghai, China;^bDepartment of Pancreatic Surgery, Shanghai General Hospital, Shanghai Key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai Jiao Tong University School of Medicine, Shanghai, China;^cCancer Metastasis Institute, Fudan University, Shanghai, China）

出处： Cancer Science 2024

关键词： ceRNA;circESYT2;ENO2;hepatocellular carcinoma progression;miR-665

摘要： Circular RNAs (circRNAs) have emerged as crucial regulators in tumor progression, yet their specific role in hepatocellular carcinoma (HCC) remains la ...

作者： Zhang, Hui^a;Zhang, Yu-Qi^a;Hu, Jian-Lin^b;Zhou, Xin-Li^aCAa （^aInstitute of Biothermal Technology, School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, 200093, China;^bDepartment of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China）

出处： Progress in Biochemistry and Biophysics 2024

关键词： cryoprotectants;microencapsulation;microfluidics;oocytes;vitrification

摘要： Objective This study aimed to develop a novel method for encapsulating oocytes in sodium alginate hydrogel using microfluidics, then to vitrify these ...