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作者: Zhang, Mili;Cao, Can;Li, Xu;Gu, Qisheng;Xu, Yixin;Zhu, Ziyan;Xu, Duogang;Wei, Shanshan;Chen, Haonan;Yang, Yuqin;Gao, Hugh;Yu, Liang;Li, Jikun (1Department of General Surgery, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China 2Institute Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China 3Department of General Surgery, Shanghai General Hospital of Nanjing Medical University, Shanghai, China 4Department of Laboratory Animal Centre, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China 5Department of Molecular and Translational Science, Monash University, Clayton Victoria,, Australia 6Department of Upper Gastrointestinal and Hepatobiliary Surgery, Monash Health, Clayton, Australia)

出处: Cancer Medicine 2023

关键词: epithelial‐mesenchymal transition;gastric cancer;microsatellite instability‐high;prognosis;tumor microenvironment

摘要: Background: Microsatellite instability‐high (MSI‐H) subgroup of gastric cancer (GC) is characterized by a high tumor mutational burden, increased lymp ...

作者: Yu-Xiang Zhang;Chen-Cheng Yao;Yu-Hua Huang;Peng Li;Er-Lei Zhi;Zi-Jue Zhu;Jian-Xiong Zhang;Fu-Jun Zhao;Zheng Li;Ru-Hui Tian (Affiliation 1 Department of Andrology, The Center for Men's Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.)

出处: Asian journal of andrology 2023

关键词: etiology;male infertility;nonobstructive azoospermia;standard mTESE;stepwise mini-incision mTESE.

摘要: Stepwise mini-incision microdissection testicular sperm extraction (mTESE) is a procedure that attempts to minimize testicular damage. However, the mi ...

作者: Li, Zongshan;Cheng, Lu;Xu, Yang;Sun, Qiao;Zhang, Jian;Bai, Lin;Feng, Ting;Tan, Song;Wang, Huan;Deng, Bolin;Li, Qiang;Gui, Yaxing;Chen, Hui (1Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 2Department of Neurology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 3Shanghai Key Laboratory of Ocular Fundus Diseases 4National Clinical Research Center for Eye Diseases 5Eye School of Chengdu University of Traditional Chinese Medicine 6School of Medicine, University of Electronic Science and Technology of China 7Chengdu Medical College 8University of Shanghai for Science and Technology)

出处: Neurology & Therapy 2023

关键词: Cerebral venous sinus thrombosis;Intracranial hypertension;Optic nerve sheath fenestration;Papilledema;Visual loss

摘要: Introduction: Progressive cerebral venous sinus thrombosis (CVST)-induced visual loss remains problematic, despite decreasing overall mortality owing ...

作者: Wang, Haoyu;Shi, Wenjie;Lu, Jing;Liu, Yuan;Zhou, Wei;Yu, Zekun;Qin, Shengying;Fan, Junwei (1Department of General Surgery, Shanghai General Hospital Affiliated to Shanghai Jiaotong University, School of Medicine, Shanghai Jiao Tong University, Shanghai 200080, China 2Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai 200030, China)

出处: Biomolecules 2023

关键词: cirrhosis;fatty acid metabolism;hepatocellular carcinoma;prognostic signature;RNA-sequencing

摘要: Hepatocellular carcinoma (HCC) ranks the most common types of cancer worldwide. As the fourth leading cause of cancer-related deaths, its prognosis re ...

作者: Fang, Ming;Li, Bin;Li, Xinming;Wang, Yudai;Zhuang, Yu (1Department of Cardiology, Hainan General Hospital, Haikou, Hainan 570311, China 2Department of Cardiology, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai 201318, China 3Department of Cardiovascular surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China)

出处: International Journal of Cardiology 2023

关键词: CAVD;miR-29b;NLRP3;SOCS1;STAT3

摘要: CAVD (calcific aortic valve disease) involves an inflammatory response similar to pyroptosis; therefore, we speculated that the progression of pyropto ...

作者: Fei Shi;Jie Hu;Ping Zheng;Yisong Lv;Hongyu Liu;Guiyun Zhang;Hongyu Jiang (Affiliations 1 Department of Neurovascular Intervention and Neurosurgery, Clinical Center of Neuroscience, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 Department of Neurosurgery, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 3 Department of Neurosurgery, Shanghai Pudong New Area People's Hospital, Shanghai, China. 4 School of Continuing Education, Shanghai Jiao Tong University, Shanghai, China. 5 Department of Neurosurgery, First Medical Center of Chinese PLA General Hospital, Beijing, China. 6 Department of Neurosurgery, Hainan Hospital of Chinese PLA General Hospital, Beijing, China. 7 Medical School of Chinese PLA, Beijing, China. 8 Department of Anesthesiology, Wuxi Second People's Hospital, Wuxi, Jiangsu Province, China.)

出处: Journal of oncology 2023

摘要: Glioma is the most common tumor in the central nervous system. High-grade gliomas confer a poor prognosis, being a serious health and economic burden. ...

作者: Zhong, Chao;Wu, Yueming;Lin, Haodong;Liu, Runhui (1State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, 200237, China 2Department of Orthopedic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China 3Jiading Branch of Shanghai General Hospital, Shanghai, 201803, China 4Frontiers Science Center for Materiobiology and Dynamic Chemistry, Shanghai Frontier Science Research Base of Optogenetic Techniques for Cell Metabolism, Research Center for Biomedical Materials of Ministry of Education, Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai, 200237, China 5East China University of Science and Technology Shenzhen Research Institute, Shenzhen 518063, China)

出处: Composites: Part B, Engineering 2023

关键词: Antimicrobial agent therapy;Immunotherapy;Osteomyelitis;Physical therapy

摘要: Osteomyelitis is a major complication of orthopedic diseases with high recurrence and morbidity, along with long hospital stays and high medical costs ...

作者: Guo, Tianjiao;Liang, Ziyun;Gu, Yun;Liu, Kun;Xu, Xun;Yang, Jie;Yu, Qi (1Institute of Medical Robotics, Shanghai Jiao Tong University, Shanghai, China 2Institute of Image Processing and Pattern Recognition, Shanghai Jiao Tong University, Shanghai, China 3School of Biomedical Engineering, Shanghai Jiao Tong Univeristy, Shanghai, China 4Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine,Shanghai, China 5National Clinical Research Center for Eye Diseases, Shanghai, China)

出处: Computer Methods & Programs in Biomedicine 2023

关键词: Convolutional neural network (CNN);Cost-sensitive;Label smoothing;Quality;Retinal image

摘要: We propose a novel retinal image quality assessment method that shows promising performance comparing with the state-of-the-art and latest works. • We ...

作者: Lang, Hong;Zhang, Hang;Ma, Mengqing;Wan, Xin;Chen, Yuyang;Sun, Qing;Cao, Changchun (1Department of Nephrology, Sir Run Run Hospital, Nanjing Medical University, 109 Longmian Road, Nanjing, Jiangsu 211166, China 2Department of Thoracic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 650 Xinsongjiang Road, Shanghai 201620, China 3Department of Nephrology, Nanjing First Hospital, Nanjing Medical University, 68 Changle Road, Nanjing, Jiangsu 210006, China)

出处: Clinica Chimica Acta 2023

关键词: Acute kidney injury;Cardiac surgery;Follistatin-like 1;Prediction;Protein array technology

摘要: Serum follistatin-like 1(Fstl1) can be used for early identification of cardiac surgery–associated AKI (CSA-AKI) and major renal adverse events. • Ser ...

作者: Xiali Liu;Huasheng Zhang;Huiqiang Ma;Jiameng Gong;Kaifeng Huang;Lu Wang;Yuting Ji;Liya Sun;Xiaoyu Wang;Li Li;Lei Shen;Shan-Yu Fung;Hong Yang (1The Province and Ministry Co-Sponsored Collaborative Innovation Center for Medical Epigenetics; Department of Pharmacology, Shanghai 201620, China;2These authors contributed equally to the paper.;3Department of Pulmonary and Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China;4Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China;5The Province and Ministry Co-Sponsored Collaborative Innovation Center for Medical Epigenetics, China;6Intensive Care Unit, The Second Hospital, Tianjin Medical University, Tianjin, 300070, China;7Department of Clinical Laboratory, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China;8Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Department of Immunology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, 300070, China)

出处: Chemical Engineering Journal 2023

摘要: Asthma is a complex, heterogeneous chronic airway inflammatory disorder, which can be simply categorized into eosinophilic and neutrophilic asthma. Al ...

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