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作者: Xingliang Zhou  1, Yiwei Liu  1   2, Yi Shen  1, Lijun Chen  3, Wenting Hu  4, Yi Yan  1, Bei Feng  1, Li Xiang  1, Yifan Zhu  1, Chenyu Jiang  1, Zihao Dai  1, Xu Huang  1, Liwei Wu  1, Tianyu Liu  1, Lijun Fu  3, Caiwen Duan  5, Shuhong Shen  4   5, Jun Li  6, Hao Zhang  1   2 (Affiliations 1 Heart Center and Shanghai Institute of Pediatric Congenital Heart Disease, Shanghai Children's Medical Center, National Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China. 2 Shanghai Clinical Research Center for Rare Pediatric Diseases, Shanghai Children's Medical Center, National Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China. 3 Department of Pediatric Cardiology, Shanghai Children's Medical Center, National Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China. 4 Department of Hematology & Oncology, Shanghai Children's Medical Center, National Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China. 5 Key Laboratory of Pediatric Hematology & Oncology of the Ministry of Health of China and Pediatric Translational Medicine Institute, Shanghai Children's Medical Center, National Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China. 6 Department of Cardiology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200080, China.)

出处: European heart journal 2024

关键词: Acute myeloid leukaemia;Cardiac energy metabolism;Chemotherapy;Interleukin 1 alpha.

摘要: Background and aims: Patients with acute myeloid leukaemia (AML) suffer from severe myocardial injury during daunorubicin (DNR)-based chemotherapy and ...

作者: Bin Zhang  1   2, Rui Yang  2   3, Hongwei Yu  4, Yamin Peng  2, Haoyu Huang  2, Meera Moydeen Abdul Hameed  5, Han Wang  4, Guixiang Zhang  1, Mohamed El-Newehy  5, Mingwu Shen  2, Xiangyang Shi  2   6, Shaojun Peng  7 (Affiliations 1 Department of Radiology, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, Shanghai 200434, China. Guixiangzhang@sina.com. 2 State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai 201620, China. xshi@dhu.edu.cn. 3 Medical School, Kunming University of Science and Technology, Kunming 650500, China. 4 Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. 5 Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia. 6 CQM-Centro de Quimica da Madeira, Universidade da Madeira, Funchal 9020-105, Portugal. 7 Center for Biological Science and Technology & College of Arts and Sciences, Beijing Normal University, Zhuhai 519087, China. 91122024006@bnu.edu.cn.)

出处: Biomaterials science 2024

摘要: Developing effective nanomedicines to cross the blood-brain barrier (BBB) for efficient glioma theranostics is still considered to be a challenging ta ...

作者: Linchen He  1, Christina Norris  2, Kimberly Palaguachi-Lopez  3, Karoline Barkjohn  4   5, Zhen Li  6, Feng Li  7, Yinping Zhang  8   9, Marilyn Black  10, Michael H Bergin  4, Junfeng Jim Zhang  11   12   13 (Affiliations 1 Department of Community and Population Health, College of Health, Lehigh University, Bethlehem, PA, USA. lih322@lehigh.edu. 2 Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. 3 Department of Community and Population Health, College of Health, Lehigh University, Bethlehem, PA, USA. 4 Department of Civil and Environmental Engineering, Duke University, Durham, NC, USA. 5 Current Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, Durham, NC, USA. 6 Department of Pediatrics, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China. 7 Department of Pulmonary Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China. 8 Department of Building Science, Tsinghua University, Beijing, China. 9 Beijing Key Laboratory of Indoor Air Quality Evaluation and Control, Beijing, China. 10 Underwriters Laboratories, Inc, Marietta, GA, USA. 11 Nicholas School of the Environment, Duke University, Durham, NC, USA. junfeng.zhang@duke.edu. 12 Duke Global Health Institute, Duke University, Durham, NC, USA. junfeng.zhang@duke.edu. 13 Duke Kunshan University, Kunshan, Jiangsu, China. junfeng.zhang@duke.edu.)

出处: Pediatric research 2024

摘要: Background: Colder temperature exposure is a known trigger for pediatric asthma exacerbation. The induction of oxidative stress is a known pathophysio ...

作者: Yanrui Jin1;Zhiyuan Li1;Chengjin Qin1CA1;Jinlei Liu1;Yunqing Liu1;Liqun Zhao2;Chengliang Liu1CA21State Key Laboratory of Mechanical System and Vibration, School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China;2Department of Cardiology, Shanghai First People’s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai 200080, China)

出处: Biomedical Signal Processing and Control 2023

关键词: Attention mechanism;Convolution neural network;ECG quality assessment;Long short-term memory neural network

摘要: ECG quality assessment is of great significance to reduce false alarms in automatic arrhythmia and other cardiovascular diseases diagnoses and reduce ...

作者: Lei Tang  1, Guo-Tong Xu  1, Jing-Fa Zhang  2 (Affiliations 1 Department of Ophthalmology of Tongji Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China. 2 Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University; National Clinical Research Center for Eye Diseases; Shanghai Key Laboratory of Ocular Fundus Diseases; Shanghai Engineering Center for Visual Science and Photomedicine; Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China.)

出处: Neural regeneration research 2023

关键词: Müller cells;anti-inflammation therapy;anti-vascular endothelial growth factor;diabetic retinopathy;hyperreflectivity foci;inflammation;inflammatory cells;inflammatory cytokines;leukostasis;microglia.

摘要: Diabetic retinopathy, characterized as a microangiopathy and neurodegenerative disease, is the leading cause of visual impairment in diabetic patients ...

作者: Chao Zhong1,2;Yueming Wu1,2;Haodong Lin3,4CA1;Runhui Liu1,5,6CA21State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, 200237, China;2C. Z. and Y. W. have equally contributed to the manuscript.;3Department of Orthopedic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China;4Jiading Branch of Shanghai General Hospital, Shanghai, 201803, China;5Frontiers Science Center for Materiobiology and Dynamic Chemistry, Shanghai Frontier Science Research Base of Optogenetic Techniques for Cell Metabolism, Research Center for Biomedical Materials of Ministry of Education, Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai, 200237, China;6East China University of Science and Technology Shenzhen Research Institute, Shenzhen 518063, China)

出处: Composites Part B: Engineering 2023

摘要: Osteomyelitis is a major complication of orthopedic diseases with high recurrence and morbidity, along with long hospital stays and high medical costs ...

作者: Chong Chen  1, Guangyi Hu, Feng'e Chen, Kun Liu, Suqin Yu, Xun Xu (Affiliation 1 Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China.)

出处: Retina (Philadelphia, Pa.) 2023

摘要: Carbon fiber microelectrodes and carbon fiber composite minielectrodes (CFM/CFCM) have been generally used for measurements of nitric oxide (NO) conce ...

作者: Yifan Zhou;Jin Wei;Qinglei Sun;Haiyun Liu;Ye Liu;Jianfeng Luo;Minwen Zhou (Affiliations 1 Department of Ophthalmology, Putuo People's Hospital, Tongji University, Shanghai 200060, China. 2 Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), School of Medicine, Shanghai JiaoTong University, Shanghai 200080, China. 3 National Clinical Research Center for Eye Diseases, Shanghai 200080, China. 4 Department of Ophthalmology, Shanghai East Hospital, Shanghai 200120, China. 5 Department of Biostatistics, School of Public Health, Fudan University, Shanghai 200032, China. 6 NHC Key Laboratory of Health Technology Assessment, Fudan University, Shanghai 200032, China. 7 Key Laboratory of Public Health Safety of Ministry of Education, Fudan University, Shanghai 200032, China.)

出处: Journal of clinical medicine 2023

关键词: China Health and Retirement Longitudinal Study;cognitive decline;hearing;sensory impairment;vision.

摘要: Previous studies on longitudinal sensory-cognition association are limited and have yielded inconsistent conclusions in western and developed countrie ...

作者: Meirong Yu;Shuang Wu;Chao Gong;Lianhua Chen (Affiliation 1 Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.)

出处: Frontiers in pharmacology 2023

关键词: C2C12 myotubes;GLUT4 translocation;Neuregulin-1β;PI3K/AKT;glucose uptake.

摘要: Insulin resistance (IR) is a feature of type 2 diabetes (T2DM) accompanied by reduced glucose uptake and glucose transporter 4 (GLUT4) translocation b ...

作者: Yinuo Wang;Junyao Zhang;Yingying Zhang;Junyan Yao (Affiliation 1 Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.)

出处: Frontiers in endocrinology 2023

关键词: Citespace;Ketogenic Diet;Neurological Diseases;Neuroprotection;Oxidative Stress;VOSviewer;bibliometric analysis;hotspots.

摘要: Background: The protective effects of Ketogenic Diet Therapies (KDTs) on neurological diseases have been extensively studied over the past two decades ...

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