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作者: Dehui Xiang;Shenshen Yan;Ying Guan;Mulin Cai;Zheqing Li;Haiyun Liu;Xinjian Chen;Bei Tian (1School of Electronic and Information Engineering, Soochow University, Suzhou, China 2Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China 3Department of Ophthalmology, Beijing Shijingshan Hospital, Beijing Shijingshan Teaching Hospital of Capital Medical University, Beijing, China 4Department of Ophthalmology, Shanghai First People’s Hospital and School of Medicine, Shanghai Jiao Tong University, Shanghai, China)

出处: IEEE Transactions on Medical Imaging 2023

关键词: Image segmentation;Retina;Lesions;Feature extraction;Fuses;Streaming media;Training

摘要: Accurate segmentation of retinal images can assist ophthalmologists to determine the degree of retinopathy and diagnose other systemic diseases. Howev ...

作者: Jiali Wu;Ke Shi;Fang Zhang;Xiaodong Sun (1Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200080, China)

出处: Journal of Clinical Medicine 2023

关键词: diabetic retinopathy;differentially expressed gene;miRNA;risk score signature

摘要: Purpose: The aim of our study was to investigate a comprehensive profile of streptozotocin (STZ)-induced early diabetic retinopathy (DR) mice to ident ...

作者: Yarong Yu;Xiaoying Ding;Lihua Yu;Ziting Lan;Yufan Wang;Jiayin Zhang (1Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, #85 Wujin Rd, 200080, Shanghai, China;2Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, #85 Wujin Rd, Shanghai, China)

出处: European Radiology 2023

关键词: Diabetes mellitus;Computed tomography angiography;Diabetic angiopathy;Adipose tissue

摘要: Objectives To investigate the predictive value of peri-coronary adipose tissue (PCAT) attenuation for microvascular complications in diabetic patient ...

作者: Jinming Cai;Jinming Cai;Haoran Xie;Yilin Yan;Zhengnan Huang;Pengfei Tang;Xiangqian Cao;Zeyi Wang;Chenkai Yang;Jiling Wen;Mingyue Tan;Fang Zhang;Bing Shen (1Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;2Department of Urology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China;3Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;4Department of Urology, Shanghai General Hospital Affiliated to Nanjing Medical University, Shanghai, China;5Department of Urology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China)

出处: Frontiers in Genetics 2023

关键词: cuproptosis;bladder cancer;lncRNAs;immunotherapy;survival analysis

摘要: Bladder cancer (BC) ranks the tenth in the incidence of global tumor epidemiology. LncRNAs and cuproptosis were discovered to regulate the cell death. ...

作者: Yangmei Xie;Ming Wang;Yiye Shao;Yinghui Chen (1Department of Neurology, Huashan Hospital, Fudan University, 12 Wulumuqi Road, 200040, Shanghai, China;2Department of Neurology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 200940, Shanghai, China)

出处: Neurochemical Research 2023

关键词: Status epilepticus;P-glycoprotein;lncNRA;H19;NF-κB signaling pathway;ceRNA

摘要: Pharmaco-resistance is a challenging problem for treatment of status epilepticus (SE) in the clinic. P-glycoprotein (P-gp) is one of the most importan ...

作者: Ge Yu;Shanshan Jin;Rui Wang;Jian Lu;Ruilan Wang (1These authors have contributed equally to this work and share first authorship.;2Department of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, No.85 Wujin Road, Shanghai 200080, China)

出处: Clinical Nutrition ESPEN 2023

关键词: Enteral nutrition;Ultrasonography;Critical illness;Feeding intolerance;Prognosis;Mortality

摘要: Background This study aimed at verifying the feasibility of transabdominal gastro-intestinal ultrasonography (TGIU) for predicting feeding intoleranc ...

作者: Lihua Yu;Xiuyu Chen;Runjianya Ling;Yarong Yu;Wenyi Yang;Jianqing Sun;Jiayin Zhang (1Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, #85 Wujin Rd, 200080, Shanghai, China;2Department of Magnetic Resonance Imaging, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease, National Centre for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China;3Institute of Diagnostic and Interventional Radiology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, #600, Yishan Rd, Shanghai, China;4Department of Cardiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, #85 Wujin Rd, Shanghai, China;5Digital Solution, Central Research Institute, United Imaging Healthcare, Shanghai, China)

出处: European Radiology 2023

关键词: Computed tomography angiography;Coronary stenosis;Fractional flow reserve;Adipose tissue

摘要: Objectives To evaluate the value of radiomics-based model of pericoronary adipose tissue (PCAT) combined with CT fractional flow reserve (CT-FFR) in ...

作者: Baojie Shi;Yuan Liu;Dehua Liu;Liyun Yuan;Wenzhi Guo;Peihao Wen;Zhaojie Su;Jie Wang;Shiquan Xu;Junjie Xia;Wenbin An;Rui Wang;Peizhen Wen;Tonghai Xing;Jinyan Zhang;Haitao Gu;Zhaowen Wang;Lin Zhong;Junwei Fan;Hao Li;Weituo Zhang;Zhihai Peng (1Organ Transplantation Clinical Medical Center of Xiamen University, Department of Organ Transplantation, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361005, Fujian, China;Organ Transplantation Institute of Xiamen University, Fujian Provincial Key Laboratory of Organ and Tissue Regeneration, School of Medicine, Xiamen University, Xiamen, 361005, Fujian, China;2Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University, 200080, Shanghai, China;3Bio-Med Big Data Center, Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 200031, Shanghai, China;4Department of General Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, Henan, China;5Organ Transplantation Institute of Xiamen University, Fujian Provincial Key Laboratory of Organ and Tissue Regeneration, School of Medicine, Xiamen University, Xiamen, 361005, Fujian, China;6Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University, 200080, Shanghai, China;Corresponding author.;7Organ Transplantation Clinical Medical Center of Xiamen University, Department of Organ Transplantation, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361005, Fujian, China;Organ Transplantation Institute of Xiamen University, Fujian Provincial Key Laboratory of Organ and Tissue Regeneration, School of Medicine, Xiamen University, Xiamen, 361005, Fujian, China;Corresponding author.;8Hongqiao International Institute of Medicine, Shanghai Tong Ren Hospital and Clinical Research Institute, Shanghai Jiao Tong University School of Medicine, 200050, Shanghai, China;Corresponding author.)

出处: EClinicalMedicine 2023

关键词: Tacrolimus;Liver transplantation;Pharmacogenomics;Precision medicine

摘要: Background: The initial dose of tacrolimus after liver transplantation (LT) is critical for rapidly achieving the steady state of the drug concentrati ...

作者: He Sun;He Sun;Zhongqing Wang;Yuxi Wang;Haichuan Rong;Danyang Wang;Xiangnian Liu;Ke Jin;Zhicheng Sun;Qiuling Fan;Qiuling Fan (1Department of Nephrology, The First Hospital of China Medical University, Shenyang, China;2Department of Endocrinology, Shengjing Hospital of China Medical University, Shenyang, China;3Department of Information Center, The First Hospital of China Medical University, Shenyang, China;4Department of Clinical Medicine, China Medical University, Shenyang, China;5Department of Nephrology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shenyang, China)

出处: Frontiers in Pharmacology 2023

关键词: sodium—glucose cotransporter 2 inhibitor;bibliometric;visualization;heart failure;diabetic cardiomyopathy;co-occurrence analysis

摘要: Background: Sodium—glucose cotransporter 2 inhibitors have proved to be extremely effective and reliable in reducing hyperglycemia, and have also been ...

作者: Xiali Liu;Huasheng Zhang;Huiqiang Ma;Jiameng Gong;Kaifeng Huang;Lu Wang;Yuting Ji;Liya Sun;Xiaoyu Wang;Li Li;Lei Shen;Shan-Yu Fung;Hong Yang (1The Province and Ministry Co-Sponsored Collaborative Innovation Center for Medical Epigenetics, Department of Pharmacology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin 300070, China; Department of Pulmonary and Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, China;2These authors contributed equally to the paper.;3Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China;4The Province and Ministry Co-Sponsored Collaborative Innovation Center for Medical Epigenetics, Department of Pharmacology, School of Basic Medical Sciences; Intensive Care Unit, The Second Hospital, Tianjin Medical University, Tianjin 300070, China;5Department of Clinical Laboratory, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, China;6Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Department of Immunology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin 300070, China)

出处: Chemical Engineering Journal 2023

摘要: Asthma is a complex, heterogeneous chronic airway inflammatory disorder, which can be simply categorized into eosinophilic and neutrophilic asthma. Al ...

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