作者： Zeyi Wang;Zhengnan Huang;Xiangqian Cao;Fang Zhang;Jinming Cai;Pengfei Tang;Chenkai Yang;Shengzhou Li;Dong Yu;Yilin Yan;Bing Shen （Department of Urology, Shanghai General Hospital of Nanjing Medical University, Shanghai, 200080, China Department of Urology, Tongji Hospital, School of Medicine, Tongji University, Shanghai, 200065, China Department of Urology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, China Department of Precision Medicine, Center of Translation Medicine, Naval Medical University, Shanghai, 200082, China Department of Urology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, China）

出处： BMC Urology 2023

关键词： Bladder cancer;Necroptosis;Tumor immune microenvironment;Prognostic model;Immunotherapy;Chemotherapy

摘要： Bladder cancer, one of the most prevalent malignant cancers, has high rate of recurrence and metastasis. Owing to genomic instability and high-level h ...

作者： Zhenguo Zi^1,2;Shujuan Du^3,2;Liming Zhang^4,2;Yuebo Wang¹;Ling Ding³;Chongqi Zhang¹;Huanyu Wang¹;Jan Pawlicki⁵;Yuan Cai⁶;Yazhou Yao⁷;Feng Zhou⁸;Yin Tong⁹;James L. Riley⁵;Qiliang Cai³CA1;Xiaojing Ma¹⁰CA2;Fang Wei¹CA3 （¹Sheng Yushou Center of Cell Biology and Immunology, Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China;²contributed equally to this study;³MOE & NHC&CAMS Key Laboratory of Medical Molecular Virology, Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Science, Shanghai Medical College, Fudan University, Shanghai 200032, China;⁴Department of Medical Laboratory, Jiangxi Cancer Hospital, Nanchang 330029, China;⁵Center for Cellular Immunotherapy, Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104;⁶Department of Pathology, Baoji Central Hospital, Baoji 721008, China;⁷Department of Hematology, Baoji Central Hospital, Baoji 721008, China;⁸Department of neurosurgery, Baoji Central Hospital, Baoji 721008, China;⁹Division of Hematology, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai, China;¹⁰Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York）

出处： Blood Advances 2023

关键词： Golgi membrane protein 1 (GOLM1);anaplastic large cell lymphoma (ALCL);anaplastic lymphoma kinase (ALK) ALCL;apoptosis;B-cell lymphoma-extra-large protein (BCL-X_L)

摘要： Golgi membrane protein 1 (GOLM1) is aberrantly expressed in many types of solid tumors and contributes to cancer development; however, its role in hem ...

作者： Nan Zhu  ¹, Haochen Guan  ^{1   2}, Xuan Wang  ¹, Yueyue Zhang  ¹, Lijie Gu  ¹, Jieshuang Jia  ¹, Ling Wang  ¹, Weijie Yuan  ¹ （Affiliations ¹ Department of Nephrology, Shanghai General Hospital, Shanghai, China. ² Department of Nephrology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Anhui, China.）

出处： International journal of medical sciences 2023

关键词： EZH2;IL-6/sIL-6R;SP4;VEGF;angiogenesis;peritoneal dialysis.

摘要： Background: Interleukin-6 (IL-6)/soluble IL-6 receptor (sIL-6R) promotes peritoneal angiogenesis by stimulating SP4-mediated vascular endothelial grow ...

作者： Mengqi Jia¹;Zhenghua Wu^1,21;Wenqing Shi³;Shuowen Wang¹;Xucong Huang¹;Min Zhang⁴;Wuping Bao⁴;Aihua Bao⁴;Pengyu Zhang⁴;Fengming Ding⁴;Guogang Xie⁴;Yuefen Lou³CA2;Guorong Fan^1,2CA3 （¹Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200080, PR China;²School of Pharmacy, Shanghai Jiao Tong University, Shanghai, PR China;³Department of Pharmacy, Shanghai Fourth People’s Hospital Affiliated to Tongji University School of Medicine, Shanghai 200434, PR China;⁴Department of Respiratory Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, PR China）

出处： Journal of Pharmaceutical and Biomedical Analysis 2023

关键词： Dried plasma spots;Online solid phase extraction;LC-MS;Tyrosine kinase inhibitors;Therapeutic drug monitoring

摘要： Gefitinib, osimertinib and icotinib are the most commonly used tyrosine kinase inhibitors (TKIs) in non-small cell lung cancer (NSCLC) with EGFR mutat ...

作者： Lin Jin;Mengjiao Zhang;Lei Sha;Mengmeng Cao;Lanyue Tong;Qingqing Chen;Cuiqin Shen;Lianfang Du;Liping Liu;Zhaojun Li （Department of Ultrasound, Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 200052, China Department of Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, 030001, Shanxi, China Department of Medical Imaging, Weifang Medical University, Weifang, 261053, Shandong, China Department of Ultrasound, Shanghai General Hospital Jiading Branch, Shanghai Jiaotong University School of Medicine, Shanghai, 201803, China Department of Ultrasound, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 100 Haining Road, Hongkou District, Shanghai, 200080, China）

出处： BMC Cardiovascular Disorders 2023

关键词： Arterial stiffness;Cardiovascular disease;Arterial pressure volume index;Risk assessment

摘要： Background and objective The new non-invasive arterial stiffness indices, arterial pressure volume index (API) is explored as a novel marker of residu ...

作者： Xuyu Gu¹;Lubing Cai²;Zhiwen Luo³;Luze Shi²;Zhen Peng²;Yaying Sun³;Jiwu Chen² （¹School of Medicine, Southeast University, Nanjing, China;²Department of Sports Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, Shanghai, China;³Department of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, China）

出处： Frontiers in Immunology 2023

关键词： lung adenocarcinoma;muscle failure index;ScRNA-seq;prognosis;immunotherapy

摘要： BackgroundIt was previously reported that the production of exerkines is positively associated with the beneficial effects of exercise in lung adenoca ...

作者： Leheng Liu¹;Leheng Liu²;Zhixia Dong³;Jinnian Cheng⁴;Xiongzhu Bu⁵;Kaili Qiu⁵;Chuan Yang⁵;Jing Wang⁶;Wenlu Niu¹;Xiaowan Wu¹;Jingxian Xu¹;Jingxian Xu²;Tiancheng Mao¹;Tiancheng Mao²;Lungen Lu¹;Lungen Lu²;Xinjian Wan³;Hui Zhou¹;Hui Zhou² （¹Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;²Shanghai Key Laboratory of Pancreatic Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, China;³Department of Gastroenterology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China;⁴Department of Gastroenterology, Shanghai Tong Ren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;⁵School of Mechanical Engineering, Nanjing University of Science and Technology, Nanjing, China;⁶Department of Pathology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China）

出处： Frontiers in Oncology 2023

关键词： deep learning;suspected superficial lesions;magnifying endoscopy with narrow band imaging (ME-NBI);gastric neoplastic lesions;convolutional neural network (CNN)

摘要： BackgroundEndoscopically visible gastric neoplastic lesions (GNLs), including early gastric cancer and intraepithelial neoplasia, should be accurately ...

作者： Nan Li¹;Chenxing Huang²;Jie Zhang³;Junyue Zhang¹;Jia Huang²;Shangshang Li¹;Xue Xia¹;Ziyu Wu¹;Chenglong Chen¹;Shuwan Tang¹;Xiangyu Xiao¹;Hui Gong²;Yuxiang Dai²CA1;Chun Mao¹CA2;Mimi Wan¹CA3 （¹National and Local Joint Engineering Research Center of Biomedical Functional Materials, School of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, China;²Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, National Clinical Research Center for Interventional Medicine, Shanghai 200433, China;³Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China）

出处： ACS Nano 2023

关键词： ischemia-reperfusion injury;nanomotors;nitric oxide;hydrogen sulfide;targeted delivery

摘要： Recombinant granulocyte colony-stimulating factor (G-CSF), with a direct repair effect on injured cardiomyocytes against myocardial infarction ischemi ...

作者： Zhengzhe Han¹;Lili Deng²;Shiyan Chen²CA;Huaping Wang²CA;Yinjun Huang³CA （¹Department of Orthopedic Surgery, and Shanghai Institute of Microsurgery on Extremities, Shanghai Sixth People's Hospital , 600 Yishan Road, Shanghai 200233, P.R. China;²State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University , Shanghai 201620, P.R. China;³Department of Trauma Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai, 201600, P.R. China）

出处： Burns & Trauma 2023

关键词： Hydrogel;Mechanical properties;Biocompatibility;Angiogenic effects;Wound healing

摘要： Background Wound healing is a process that requires angiogenesis and antibacterial activities and it remains a challenge for both experimental and cl ...

作者： Hanhao Dai  ¹, Jun Luo  ², Lili Deng  ³, Chao Song  ¹, Zhibo Deng  ¹, Yijing Wu  ¹, Song Gu  ⁴, Jie Xu  ^{1   2} （Affiliations ¹ Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350000, China. ² Department of Orthopedics, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, 350000, China. ³ State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai, 201620, China. ⁴ Trauma Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China.）

出处： Advanced healthcare materials 2023

关键词： Extracellular vesicle;MicroRNA;Myogenesis;Sarcopenia;Stemness.

摘要： Sarcopenia is a geriatric disease characterized by reduced muscle function and mass. The capacity to self-renew and myogenesis of satellite cells (SCs ...