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作者: Mingming Ma;Shuzhi Zhao;Chenxin Li;Min Tang;Tao Sun;Zhi Zheng (Affiliations 1 Department of Ophthalmology, Shanghai General Hospital, National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, China. 2 Shanghai Eye Diseases Prevention &Treatment Center/ Shanghai Eye Hospital, China. Electronic address: drsuntao@yeah.net. 3 Department of Ophthalmology, Shanghai General Hospital, National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, China. Electronic address: zzheng88@sjtu.edu.cn.)

出处: Experimental eye research 2023

关键词: Diabetic retinopathy;EP300;Müller cells;Pyroptosis;Transient receptor potential channel 6.

摘要: Background: Transient receptor potential channel 6 (TRPC6) is reported to be involved in the pathogenesis of diabetic complications, but its role in d ...

作者: Weixing Zhang;Juan Du;Tonghe Zhu;Ruilan Wang (Affiliations 1 Department of Critical Care Medicine, School of Medicine, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China. 2 School of Chemistry and Chemical Engineering, Shanghai Engineering Research Center of Pharmaceutical Intelligent Equipment, Shanghai Frontiers Science Research Center for Druggability of Cardiovascular Non-coding RNA, Institute for Frontier Medical Technology, Shanghai University of Engineering Science, Shanghai, China.)

出处: Frontiers in bioengineering and biotechnology 2023

关键词: SiO2 nanosphere;antibacterial;blood compatibility;catheter;superhydrophobic.

摘要: Catheter infection is the most common complication after vascular catheter placement, which seriously threatens the survival of critically ill patient ...

作者: Pengcheng Xu;Xuefeng Wang;Jiaci Shi;Wei Chen;Zhan-Jun Lu;Hao Jia;Daixin Ye;Xinxin Li (Affiliations 1 State Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai200050, China. 2 School of Microelectronics, University of Chinese Academy of Sciences, Beijing100049, China. 3 Department of Emergency, Tongji Hospital, Tongji University School of Medicine, Shanghai200065, China. 4 Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai200080, China. 5 Department of Chemistry, Institute for Sustainable Energy, College of Sciences, Shanghai University, Shanghai200444, China.)

出处: Nano letters 2023

关键词: Mixed-dimensional nanostructure;living cells;metal−organic framework;microsensors;neurotransmitters.

摘要: Neurotransmitter exocytosis of living cells plays a vital role in neuroscience. However, the available amperometric technique with carbon fiber electr ...

作者: Juzhao Zhang;Haidong Zou (Affiliations 1 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 Shanghai Eye Diseases Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China. 3 National Clinical Research Center for Eye Diseases, Shanghai, China. 4 Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China.)

出处: Frontiers in cell and developmental biology 2023

关键词: artificial intelligence;classification;deep learning;machine learning;myopia;risk prediction;semantic segmentation.

摘要: Myopia is a significant global health concern and affects human visual function, resulting in blurred vision at a distance. There are still many unsol ...

作者: Lili Deng;Liu Wang;Li Li;Zuguang Gong;Ruilan Wang;Wendi Fei;Yingshan Zhou;Fang Wang (Affiliations 1 Department of Critical Care Medicine, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 201620, China. 2 Department of Orthopaedics and Traumatology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200120, China. 3 College of Materials Science and Engineering and Key Laboratory of Green Processing and Functional Textiles of New Textile Materials, Ministry of Education, Wuhan Textile University, Wuhan 430073, China.)

出处: ACS applied bio materials 2023

关键词: absorbable;chitosan;femoral artery;gauze dressing;gelling fiber;hemostasis.

摘要: Death from lethal hemorrhage remains a major problem in various emergency scenarios. There is a continuous interest in the development of absorbable h ...

作者: Yiran Gu;Zhiyun Ding;Qin Zhou;Juan Li;Wenyan Qian (Affiliations 1 Department of Gyanecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shang hai 201620, PR China. 2 Department of Gynaecology, Kunshan Hospital of Traditional Chinese Medicine Affiliated to Yangzhou University, Kunshan, Jiangsu 215300, PR China. 3 Department of Gynaecology, Kunshan Hospital of Traditional Chinese Medicine Affiliated to Yangzhou University, Kunshan, Jiangsu 215300, PR China. Electronic address: wy_q1987@alumni.sjtu.edu.cn.)

出处: Reproductive biology 2023

关键词: Epithelial-mesenchymal transition;JARID2;Ovarian endometriosis.

摘要: Recently, it has been proposed that epithelial-mesenchymal transition (EMT) plays a key role in the development of endometriosis (EMs). Although EMs i ...

作者: Liyan Gu;Jian Chang;Ji Wang;Ping Feng;Hao Xu (Affiliations 1 Department of Neurology, 905th Hospital of the PLA Navy, Shanghai, China. 2 Nursing Department, Shanghai General Hospital, School of Nursing, Shanghai Jiao Tong University, Shanghai, China. 3 Nursing Department, 905th Hospital of the PLA Navy, Shanghai, China. 4 Nursing Department, Changhai Hospital, Naval Medical University, Shanghai, China. 5 Department of Infectious Diseases, Changhai Hospital, Naval Medical University, Shanghai, China.)

出处: Frontiers in public health 2023

关键词: COVID-19;Fangcang Shelter Hospital;latent profile analysis;stress load;work-related stressors.

摘要: The Omicron wave of the COVID-19 pandemic significantly affected Shanghai, China, from March to June 2022. Numbers of Fangcang Shelter Hospitals (FSHs ...

作者: Yucui Zhao;Tingting Lu;Yanwei Song;Yanqin Wen;Zheng Deng;Jiahui Fan;Minghui Zhao;Ruyi Zhao;Yuntao Luo;Jianzhu Xie;Binjie Hu;Haoran Sun;Yiwei Wang;Sijia He;Yanping Gong;Jin Cheng;Xinjian Liu;Liang Yu;Jikun Li;Chuanyuan Li;Yongyong Shi;Qian Huang (Affiliations 1 Shanghai Key Laboratory for Pancreatic Diseases and Cancer Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China. 2 Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, 200030, China. 3 Zhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, China. 4 Department of Biochemistry, School of Medicine, Sun Yat-sen University, Shenzhen, 518107, China. 5 Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China. 6 Department of Dermatology, Duke University Medical Center, Box 3135, Durham, NC, 27710, USA. 7 Biomedical Sciences Institute of Qingdao University (Qingdao Branch of SJTU Bio-X Institutes), Qingdao University, Qingdao, 266003, China.)

出处: Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023

关键词: poly-aneuploid giant cancer cells;radiation tolerant persister;radio-resistance;tumor repopulation.

摘要: Repopulation of residual tumor cells impedes curative radiotherapy, yet the mechanism is not fully understood. It is recently appreciated that cancer ...

作者: Yanfei Zhang;Chenhong Gu;Ying Lei;Jingwen Wang;Leiqin Sun;Junwei Fan;Yanlin Wang;Xiaoqing Zhang (Affiliations 1 Department of Pharmacy, The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. 2 Shanghai Key Laboratory of Embryo Original Diseases, Shanghai, China. 3 Department of General Surgery, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. 4 Division of Maternal-Fetal Fetal Medicine, Prenatal Diagnosis Center, The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.)

出处: Frontiers in nutrition 2023

关键词: folate;homocysteine;methylenetet-rahydrofolate reductase;one-carbon metabolism;pregnancy-induced hypertension;vitamin B12.

摘要: Background and objective: A considerable number of pregnant women who were supplemented with folate and vitamin B12 were selected as major participant ...

作者: Jiancheng Yang;Rui Shi;Donglai Wei;Zequan Liu;Lin Zhao;Bilian Ke;Hanspeter Pfister;Bingbing Ni (Affiliations 1 Shanghai Jiao Tong University, Shanghai, China. 2 Boston College, Chestnut Hill, MA, USA. 3 RWTH Aachen University, Aachen, Germany. 4 Department of Endocrinology and Metabolism, Fudan Institute of Metabolic Diseases, Zhongshan Hospital, Fudan University, Shanghai, China. 5 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 6 Harvard University, Cambridge, MA, USA. 7 Shanghai Jiao Tong University, Shanghai, China. nibingbing@sjtu.edu.cn.)

出处: Scientific data 2023

摘要: We introduce MedMNIST v2, a large-scale MNIST-like dataset collection of standardized biomedical images, including 12 datasets for 2D and 6 datasets f ...

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