作者： Yung-Chiang Liu⁶¹;Ping Chen⁶²³;Ray Chang¹;Xingjian Liu¹;Jhe-Wei Jhang¹;Myagmartsend Enkhbat⁴;Shan Chen¹;Hongxia Wang⁵;Chuxia Deng⁷²;Peng-Yuan Wang⁷¹ （¹Oujiang Laboratory;Key Laboratory of Alzheimer's Disease of Zhejiang Province, Institute of Aging, Wenzhou Medical University, Wenzhou, Zhejiang 325024, People's Republic of China;²Cancer Centre, Faculty of Health Sciences, MOE Frontier Science Centre for Precision Oncology, University of Macau, Macau SAR 999078, People's Republic of China;³Department of Oncology, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, People's Republic of China;⁴Department of Chemical Engineering, University of Waterloo, 200 University Avenue West, Waterloo, ON N2L 3G1, Canada;⁵State Key Laboratory of Oncogenes and Related Genes, Department of Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China）

出处： Biofabrication 2024

摘要： The tumor microenvironment (TME) is critical for tumor growth and metastasis. The TME contains cancer-associated cells, tumor matrix, and tumor secret ...

作者： Shuli Chen^1,2,3,4;Yi Xu^1,3,4;Bo Chen⁶;Senlin Lin^1,3,4CA1;Lina Lu^1,3,4;Minna Cheng⁵;Yuheng Wang⁵;Qinping Yang⁵;Saiguang Ling⁷;Dengji Zhou⁷;Yan Shi^5,8CA2;Haidong Zou^1,2,3,4CA3;Yingyan Ma^1,2,3,4CA4 （¹Department of Eye Disease Control and Prevention, Shanghai Eye Disease Prevention & Treatment Center/Shanghai Eye Hospital, School of Medicine, Tongji University, No. 1440, Hongqiao Road, 200336, Shanghai, China;²Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 100, Haining Road, 200080, Shanghai, China;³National Clinical Research Center for Eye Diseases, Shanghai, China;⁴Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China;⁵Department of Chronic Non-Communicable Diseases and Injury, Shanghai Municipal Center for Disease Control & Prevention, No. 1380, West Zhongshan Road, Shanghai, China;⁶School of Public Health, Fudan University, No. 130, Dongan Road, Shanghai, China;⁷EVision technology (Beijing) co. LTD, 100085, Beijing, China;⁸National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, No. 12, Middle Wulumuqi Road, Shanghai, China）

出处： Lipids in Health and Disease 2024

关键词： Diabetic retinopathy;Remnant cholesterol;Retinal vessels;Type 2 diabetes mellitus

摘要： Background The association between remnant cholesterol (RC) and diabetic retinopathy (DR) in type 2 diabetes mellitus (T2DM) remains unclear. Morphol ...

作者： Yang Li  ¹, Jun Cao  ^{1   2}, Jianfeng Wang  ¹, Weidong Wu  ¹, Liren Jiang  ³, Xing Sun  ¹ （Affiliations ¹ Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of General Surgery, Shanghai Jiangqiao Hospital, Shanghai General Hospital Jiading Branch, Shanghai, China. ³ Department of Pathology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Cancer 2024

关键词： IGF2BP3;brain metastasis;breast cancer;prognosis;tumor progression.

摘要： Background: This study aimed to determine the role of insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3), an N⁶ -methyladinosine ...

作者： Yiting Li  ¹, Yibin Zeng  ², Zile Chen  ¹, Shu Nie  ¹, Zhouwei Wu  ¹ （Affiliations ¹ Department of Dermatology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of Dermatology, Minhang Hospital, Fudan University, Shanghai, China.）

出处： Journal of cosmetic dermatology 2024

关键词： acne;efficiency;isotretinoin;low-dosage;safety.

摘要： Background: Acne vulgaris is one of the most common skin conditions in dermatology clinics. Accumulating evidence has implicated oral low-dosage isotr ...

作者： Zhexin Lu  ¹, Jin Huang  ², Yongliang Fan  ¹, Hongbing Gu  ¹, Xian Zhu  ³, Min Yu  ¹, Yizhou Ye  ¹ （Affiliations ¹ Department of Cardiovascular Surgery, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China. ² Department of Nursing, Shanghai East Hospital, Tong Ji University, School of Medicine, Shanghai, China. ³ Department of Emergency and Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.）

出处： Journal of medical imaging and radiation oncology 2024

关键词： endovascular total aortic arch repair;in situ fenestration;supra-arch branch revascularization.

摘要： Introduction: Ascending aorta or hemi-arch replacement is a frequently used treatment for patients with acute type A thoracic aortic dissection, parti ...

作者： Qingnan Zhao  ^{1   2}, Yijiong Tan  ¹, Qinqin Wu  ³, Xiangqin Xiao  ¹, Xinyi Wei  ⁴, Mengqing Nian  ⁵, Jie Yao  ⁵, Nengguang Fan  ⁶, Ruiping Wang  ⁷, Guorong Fan  ¹ （Affiliations ¹ Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Shanghai Key Laboratory of Pancreatic Disease, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ Department of Pharmacy, Community Health Service Center of Guangfulin Street, Shanghai, China. ⁴ School of Public Health, Nanjing Medical University, Nanjing, China. ⁵ School of pharmacy, Nanjing Medical University, Nanjing, China. ⁶ Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁷ Clinical Research Center, Shanghai Skin Diseases Hospital, Tongji Medical University, Shanghai, China.）

出处： Expert opinion on drug safety 2024

关键词： Type 2 diabetes mellitus;dapagliflozin;diabetic ketoacidosis;diabetic ketosis;risk factor.

摘要： Background: There is limited evidence on the safety of sodium-glucose co-transporter-2 inhibitor (SGLT2i) use in the real world of China. We conducted ...

作者： Qingqing Zhang  ^{1   2}, Bingye Zhu  ³, Hongyan Yang  ⁴, Fei Li  ^{1   2}, Ying Qu  ^{1   2}, Lungen Lu  ^{1   2}, Qidi Zhang  ^{1   2} （Affiliations ¹ Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Shanghai Key Laboratory of Pancreatic Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ³ Department of Urology, Affiliated Nantong Hospital of Shanghai University, The Sixth People's Hospital of Nantong, Nantong, Jiangsu Province, China. ⁴ Nursing Department, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： The journal of gene medicine 2024

关键词： YBX1;liver hepatocellular carcinoma;prognosis;single-cell and bulk sequencing analysis;tumor immunity.

摘要： Background: Y-box binding protein 1 (YBX1) plays a variety of roles in progression of multiple tumors. However, the role of YBX1 in prognostic value a ...

作者： Siteng Chen  ¹, Feng Gao  ², Tuanjie Guo  ³, Liren Jiang  ², Ning Zhang  ⁴, Xiang Wang  ³, Junhua Zheng  ¹ （Affiliations ¹ Department of Urology, Renji Hospital. ² Department of Pathology. ³ Department of Urology, Shanghai General Hospital. ⁴ Department of Urology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.）

出处： International journal of surgery (London, England) 2024

摘要： Background: Although separate analysis of individual factor can somewhat improve the prognostic performance, integration of multimodal information int ...

作者： Mengchen Wu  ¹, Yingxiang Hao  ¹, Xinwan Wu  ¹, Minmin Zhu  ^{1   2}, Xiangyuan Chen  ¹, Jie Qi  ¹, Zhuang Yu  ¹, Hongjiao Xu  ¹ （Affiliations ¹ Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, China. ² Department of Anesthesiology, Department of Oncology, Fudan University Shanghai Cancer Center, Shanghai Medical College, Fudan University, Shanghai 200032, China.）

出处： Acta biochimica et biophysica Sinica 2024

关键词： diabetic nephropathy;endothelial-to-mesenchymal transition;glomerular endothelial cell, SirT7.

摘要： Diabetic nephropathy (DN) is the main cause of end-stage renal disease worldwide. It is reported that the endothelial-to-mesenchymal transition (EndMT ...

作者： Rongxin Yu  ¹, Hongping Chen  ¹, Jian He  ², Zhichao Zhang  ³, Jiajing Zhou  ⁴, Qinqin Zheng  ¹, Zhouping Fu  ¹, Chengyin Lu  ¹, Zhixing Lin  ⁵, Frank Caruso  ⁵, Xiangchun Zhang  ¹ （Affiliations ¹ Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou, 310008, China. ² College of Basic Medical and Forensic Medicine, Henan University of Science and Technology, Luoyang, 471000, China. ³ Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 200000, China. ⁴ College of Biomass Science and Engineering, Sichuan University, Chengdu, 610065, China. ⁵ Department of Chemical Engineering, The University of Melbourne, Parkville, Victoria, 3010, Australia.）

出处： Advanced materials (Deerfield Beach, Fla.) 2024

关键词： biofilms;metal-organic materials;polyphenols;quinoprotein;selective antimicrobial.

摘要： Antibiotic-resistant bacteria pose a global health threat by causing persistent and recurrent microbial infections. To address this issue, antimicrobi ...