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作者: Xuhui Fan  1, Ni Xie  2, Jingwen Chen  1, Tiewen Li  3, Rong Cao  1, Hongwei Yu  1, Meijuan He  1, Zilin Wang  1, Yihui Wang  1, Hao Liu  4, Han Wang  1   2   5, Xiaorui Yin  1 (Affiliations 1 Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 Institution for Clinical Research, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 3 Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 4 Department of Research and Development, Yizhun Medical AI Technology Co. Ltd., Beijing, China. 5 Department of Radiology, Jiading Branch of Shanghai General Hospital, Shanghai, China.)

出处: Frontiers in oncology 2022 Vol.12 P839621

关键词: biological characteristics;magnetic resonance imaging;prostate cancer;radiomics;risk stratification.

摘要: Objectives: This study aims to develop and evaluate multiparametric MRI (MP-MRI)-based radiomic models as a noninvasive diagnostic method to predict s ...

作者: Zhiwei Qin1;Chongzhi Zhou1CA1 (1 Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 85 Wujin Road, Shanghai, China)

出处: Experimental Hematology & Oncology 2022 Vol.11 No.1

关键词: Gastric cancer;HOXA13;FN1;FAK/Src;miR-449a

摘要: Background Gastric cancer (GC) is one of the most common cancers causing a poor prognosis worldwide. HOXA13, as a member of the homeobox (HOX) family ...

作者: Ming Wang  1, Yangmei Xie  1, Yiye Shao  2, Yinghui Chen  1 (Affiliations 1 Department of Neurology, Huashan Hospital, Fudan University. 2 Department of Neurology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine.)

出处: Biological & pharmaceutical bulletin 2022 Vol.45 No.1 P86-93

关键词: inflammation;microglia;nuclear factor-kappaB (NF-κΒ) signaling pathway;small nucleolar RNA host gene 5;status epilepticus.

摘要: Status epilepticus (SE) induced inflammation plays an important role in the pathogenesis of SE. Long non-coding RNA small nucleolar RNA host gene 5 (l ...

作者: Lingling Zhuang  1, Xu Ming  2, Jun Liu  2, Chao Jia  1, Yubiao Jin  3, Jing Wang  3, Qiusheng Shi  1, Rong Wu  1, Lifang Jin  1, Lianfang Du  1 (Affiliations 1 Department of Medical Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China. 2 Department of Breast-Thyroid-Vascular Surgery, Shanghai General Hospital, Shanghai JiaoTong University, School of Medicine, Shanghai, China. 3 Department of Pathology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.)

出处: The British journal of radiology 2022 Vol.95 No.1130 P20210897

摘要: Objectives: This study aimed to compare diagnostic efficiency for axillary sentinel lymph node (SLN) metastasis between lymphatic contrast-enhanced ul ...

作者: Siteng Chen #  1, Encheng Zhang #  1, Tuanjie Guo #  1, Jialiang Shao  1, Tao Wang  1, Ning Zhang  2, Xiang Wang  3, Junhua Zheng  4 (Affiliations 1 Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 Department of Urology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. zn12235@rjh.com.cn. 3 Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. seanw_hs@163.com. 4 Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. zhengjh0471@sina.com.)

出处: BMC cancer 2022 Vol.22 No.1 P1

关键词: Cell cycle;Clear cell renal cell carcinoma;Ferroptosis;Nomogram;Prognosis.

摘要: Background: It is of great urgency to explore useful prognostic markers for patients with clear cell renal cell carcinoma (ccRCC). Prognostic models b ...

作者: Xu, Huayun1;Wang, Songpo1;Gao, Xiaohong2;Wang, Guozeng3 (1 Department of Traditional Chinese Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China 2 Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China 3 Department of Obstetrics and Gynecology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China)

出处: Evidence-based Complementary & Alternative Medicine (eCAM) 2022 P1-7

摘要: Objective. To evaluate the efficacy and safety of Yushen Tongluo Granule (YSTLG) combined with clomiphene citrate (CC) in the treatment of anovulatory ...

作者: Yuan Yuan #  1, Guangjian Fan #  2, Yuqi Liu #  1, Lu Liu  3, Tong Zhang  1, Pengfei Liu  1, Qing Tu  1, Xinyi Zhang  1, Shiyuan Luo  4, Liangfang Yao  5, Feng Chen  6, Jingbao Li  7 (Affiliations 1 Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 201620, China. 2 Precision Research Center for Refractory Diseases, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 201620, China. 3 Department of Anesthesiology, Weifang Medical University, Weifang, 261000, China. 4 Department of Anesthesiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China. 5 Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 201620, China. yao_elina@163.com. 6 Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 201620, China. smmuchenfeng@163.com. 7 Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 201620, China. lijingbaoshanghai@163.com.)

出处: Cellular & molecular immunology 2022

关键词: Glycolysis;HK2;KLF14;Macrophages;Perhexiline;Sepsis.

摘要: Sepsis is a heterogeneous syndrome induced by a dysregulated host response to infection. Glycolysis plays a role in maintaining the immune function of ...

作者: Ling Shen  1, Peng Gu  2, Chen Qiu  3, Wen-Tao Ding  2, Lei Zhang  4, Wan-Yue Cao  2, Zu-Yin Li  5, Bin Yan  6, Xing Sun  7 (Affiliations 1 Clinical Medical School, Shanghai General Hospital of Nanjing Medical University, Shanghai, China; Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 3 Institute of Gallstone Disease, Center of Gallbladder Disease, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China. 4 Intervention Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 5 Department of Hepatobiliary Surgery, Peking University Organ Transplantation Institute, Peking University People\'s Hospital, Beijing, China. 6 Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: yanbin8988@sjtu.edu.cn. 7 Clinical Medical School, Shanghai General Hospital of Nanjing Medical University, Shanghai, China; Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: xingsun_sjtu@aliyun.com.)

出处: Annals of hepatology 2022 P100680

关键词: EMT;Hepatocellular carcinoma;LPCAT1;Migration and invasion;Wnt/β-catenin pathway.

摘要: Introduction and objectives: Hepatocellular carcinoma (HCC) is one of the most malignant digestive tumors, and its insidious onset and rapid progressi ...

作者: Binghang Li  1, Fei Li  1, Tianyi Gu  1, Yuecheng Guo  1, Bo Shen  1, Xianjun Xu  1, Zhenyang Shen  1, Liuying Chen  2, Qidi Zhang  1, Hui Dong  1, Xiaobo Cai  3, Lungen Lu  4 (Affiliations 1 Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 201620, China; Shanghai Key Laboratory of Pancreatic Diseases, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 201620, China. 2 Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. 3 Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 201620, China; Shanghai Key Laboratory of Pancreatic Diseases, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 201620, China. Electronic address: caixiaobo19790719@126.com. 4 Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 201620, China; Shanghai Key Laboratory of Pancreatic Diseases, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 201620, China. Electronic address: lungenlu1965@163.com.)

出处: European journal of pharmacology 2022 P174866

关键词: Hepatic progenitor cell;Liver fibrosis;Y-box binding protein 1;p53.

摘要: The proliferation of hepatic progenitor cells (HPCs) contributes to liver regeneration and fibrogenesis during chronic liver injury; however, the mech ...

作者: Qidi Zhang #  1, Ying Qu #  1, Qingqing Zhang  2, Fei Li  1, Binghang Li  1, Zhenghong Li  1, Yuwei Dong  1, Lungen Lu  3, Xiaobo Cai  4 (Affiliations 1 Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, No. 650 New Songjiang Road, Shanghai, 201620, China. 2 Department of Gastroenterology, Ruian People\'s Hospital, No. 108 Wansong Road, Ruian, 325200, China. 3 Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, No. 650 New Songjiang Road, Shanghai, 201620, China. lungenlu1965@163.com. 4 Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, No. 650 New Songjiang Road, Shanghai, 201620, China. caixiaobo1979@hotmail.com.)

出处: Cell biology and toxicology 2022

关键词: Exosome;Fe2+;Ferroptosis;Hepatic stellate cell;Hepatitis B virus;Hepatocytes;Lipid ROS;Liver fibrosis;Transferrin receptor;miR-222.

摘要: Exosomal miRNAs activates hepatic stellate cell (HSC) and promote fibrosis. miR-222 was found to be increased in hepatitis B virus (HBV)-infected hepa ...

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