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作者: Yanrui Jin1;Zhiyuan Li1;Chengjin Qin1CA1;Jinlei Liu1;Yunqing Liu1;Liqun Zhao2;Chengliang Liu1CA21State Key Laboratory of Mechanical System and Vibration, School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China;2Department of Cardiology, Shanghai First People’s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai 200080, China)

出处: Biomedical Signal Processing and Control 2023

关键词: Attention mechanism;Convolution neural network;ECG quality assessment;Long short-term memory neural network

摘要: ECG quality assessment is of great significance to reduce false alarms in automatic arrhythmia and other cardiovascular diseases diagnoses and reduce ...

作者: Lei Tang  1, Guo-Tong Xu  1, Jing-Fa Zhang  2 (Affiliations 1 Department of Ophthalmology of Tongji Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China. 2 Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University; National Clinical Research Center for Eye Diseases; Shanghai Key Laboratory of Ocular Fundus Diseases; Shanghai Engineering Center for Visual Science and Photomedicine; Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China.)

出处: Neural regeneration research 2023

关键词: Müller cells;anti-inflammation therapy;anti-vascular endothelial growth factor;diabetic retinopathy;hyperreflectivity foci;inflammation;inflammatory cells;inflammatory cytokines;leukostasis;microglia.

摘要: Diabetic retinopathy, characterized as a microangiopathy and neurodegenerative disease, is the leading cause of visual impairment in diabetic patients ...

作者: Chao Zhong1,2;Yueming Wu1,2;Haodong Lin3,4CA1;Runhui Liu1,5,6CA21State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, 200237, China;2C. Z. and Y. W. have equally contributed to the manuscript.;3Department of Orthopedic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China;4Jiading Branch of Shanghai General Hospital, Shanghai, 201803, China;5Frontiers Science Center for Materiobiology and Dynamic Chemistry, Shanghai Frontier Science Research Base of Optogenetic Techniques for Cell Metabolism, Research Center for Biomedical Materials of Ministry of Education, Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai, 200237, China;6East China University of Science and Technology Shenzhen Research Institute, Shenzhen 518063, China)

出处: Composites Part B: Engineering 2023

摘要: Osteomyelitis is a major complication of orthopedic diseases with high recurrence and morbidity, along with long hospital stays and high medical costs ...

作者: Chong Chen  1, Guangyi Hu, Feng'e Chen, Kun Liu, Suqin Yu, Xun Xu (Affiliation 1 Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China.)

出处: Retina (Philadelphia, Pa.) 2023

摘要: Carbon fiber microelectrodes and carbon fiber composite minielectrodes (CFM/CFCM) have been generally used for measurements of nitric oxide (NO) conce ...

作者: Yifan Zhou;Jin Wei;Qinglei Sun;Haiyun Liu;Ye Liu;Jianfeng Luo;Minwen Zhou (Affiliations 1 Department of Ophthalmology, Putuo People's Hospital, Tongji University, Shanghai 200060, China. 2 Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), School of Medicine, Shanghai JiaoTong University, Shanghai 200080, China. 3 National Clinical Research Center for Eye Diseases, Shanghai 200080, China. 4 Department of Ophthalmology, Shanghai East Hospital, Shanghai 200120, China. 5 Department of Biostatistics, School of Public Health, Fudan University, Shanghai 200032, China. 6 NHC Key Laboratory of Health Technology Assessment, Fudan University, Shanghai 200032, China. 7 Key Laboratory of Public Health Safety of Ministry of Education, Fudan University, Shanghai 200032, China.)

出处: Journal of clinical medicine 2023

关键词: China Health and Retirement Longitudinal Study;cognitive decline;hearing;sensory impairment;vision.

摘要: Previous studies on longitudinal sensory-cognition association are limited and have yielded inconsistent conclusions in western and developed countrie ...

作者: Meirong Yu;Shuang Wu;Chao Gong;Lianhua Chen (Affiliation 1 Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.)

出处: Frontiers in pharmacology 2023

关键词: C2C12 myotubes;GLUT4 translocation;Neuregulin-1β;PI3K/AKT;glucose uptake.

摘要: Insulin resistance (IR) is a feature of type 2 diabetes (T2DM) accompanied by reduced glucose uptake and glucose transporter 4 (GLUT4) translocation b ...

作者: Yinuo Wang;Junyao Zhang;Yingying Zhang;Junyan Yao (Affiliation 1 Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.)

出处: Frontiers in endocrinology 2023

关键词: Citespace;Ketogenic Diet;Neurological Diseases;Neuroprotection;Oxidative Stress;VOSviewer;bibliometric analysis;hotspots.

摘要: Background: The protective effects of Ketogenic Diet Therapies (KDTs) on neurological diseases have been extensively studied over the past two decades ...

作者: Yu Ding;Wenhua Li;Shi Peng;Genqing Zhou;Songwen Chen;Yong Wei;Juan Xu;Hongbing Gu;Jiayong Li;Shaowen Liu;Bei Liu (Affiliations 1 Cardiology Department, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine. 2 Department of Cardiology, Wujin Hospital Affiliated with Jiangsu University, the Wujin Clinical College of Xuzhou Medical University. 3 Cardiovascular Surgery Department, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine. 4 Inspection Department, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine.)

出处: Biological & pharmaceutical bulletin 2023

关键词: ferroptosis;iron;ischemia/reperfusion;lipid peroxidation;puerarin.

摘要: This study investigated whether pretreatment with puerarin could alleviate myocardial ischemia/reperfusion (I/R) injury in a cardiomyocyte oxygen-gluc ...

作者: Zeyi Wang;Zhengnan Huang;Xiangqian Cao;Fang Zhang;Jinming Cai;Pengfei Tang;Chenkai Yang;Shengzhou Li;Dong Yu;Yilin Yan;Bing Shen (Affiliations 1 Department of Urology, Shanghai General Hospital of Nanjing Medical University, Shanghai, 200080, China. 2 Department of Urology, Tongji Hospital, School of Medicine, Tongji University, Shanghai, 200065, China. 3 Department of Urology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, China. 4 Department of Precision Medicine, Center of Translation Medicine, Naval Medical University, Shanghai, 200082, China. yudong615@126.com. 5 Department of Urology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, China. yyl13338729720@163.com. 6 Department of Urology, Shanghai General Hospital of Nanjing Medical University, Shanghai, 200080, China. urodrshenbing@shsmu.edu.cn. 7 Department of Urology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, China. urodrshenbing@shsmu.edu.cn.)

出处: BMC urology 2023

关键词: Bladder cancer;Chemotherapy;Immunotherapy;Necroptosis;Prognostic model;Tumor immune microenvironment.

摘要: Bladder cancer, one of the most prevalent malignant cancers, has high rate of recurrence and metastasis. Owing to genomic instability and high-level h ...

作者: Jinming Cai;Haoran Xie;Yilin Yan;Zhengnan Huang;Pengfei Tang;Xiangqian Cao;Zeyi Wang;Chenkai Yang;Jiling Wen;Mingyue Tan;Fang Zhang;Bing Shen (Affiliations 1 Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 Department of Urology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China. 3 Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 4 Department of Urology, Shanghai General Hospital Affiliated to Nanjing Medical University, Shanghai, China. 5 Department of Urology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.)

出处: Frontiers in genetics 2023

关键词: bladder cancer;cuproptosis;immunotherapy;lncRNAs;survival analysis.

摘要: Bladder cancer (BC) ranks the tenth in the incidence of global tumor epidemiology. LncRNAs and cuproptosis were discovered to regulate the cell death. ...

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