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作者: Yang Yu1;Hongqing Zhu1CA1;Tianwei Qian2;Ning Chen1;Bingcang Huang31School of Information Science and Engineering, East China University of Science and Technology, Shanghai, 200237, China;2Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 200080, China;3Department of Radiology, Gongli Hospital of Shanghai Pudong New Area, 219 Miaopu Road, Pudong New Area, Shanghai 200135, China)

出处: Pattern Recognition 2026

摘要: Automatic diagnosis of fundus diseases is crucial for clinical decision support. Existing single-modality and single-aware methods often underutilize ...

作者: Yiming Zhang1;Hongqing Zhu1CA1;Tianwei Qian2CA2;Ning Chen1;Xun Xu2;Bingcang Huang31School of Information Science and Engineering, East China University of Science and Technology, Shanghai 200237, China;2Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai 200080, China;3Department of Radiology, Gongli Hospital of Shanghai Pudong New Area, Shanghai 200135, China)

出处: Information Fusion 2026

关键词: Macular edema diagnosis;Mamba;GCN;Multi-branch fusion

摘要: Macular edema is a retinal disease that severely impairs vision, necessitating timely and accurate diagnosis for effective clinical treatment. However ...

作者: Qing Liu1;Hongqing Zhu1CA1;Tianwei Qian2;Bingcang Huang3;Ying Wang41School of Information Science and Engineering, East China University of Science and Technology, Shanghai 200237, China;2Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai 200080, China;3Department of Radiology, Gongli Hospital of Shanghai Pudong New Area, Shanghai 200135, China;4Sino-French Cooperative Central Lab, Gongli Hospital of Shanghai Pudong New Area, 219 Miaopu Road, Pudong New Area, Shanghai 200135, China)

出处: Information Fusion 2026

关键词: Cross-modal Mamba fusion;Retinal disease diagnosis;Mamba;CLIP auxiliary;OCT and CFP

摘要: The high prevalence of retinal diseases has made early diagnosis a critical focus in ophthalmology research. Owing to the diversity of imaging modalit ...

作者: Lingfeng Yu1,2,3;Qi Wu4,3;Fei Jin5,3;Yixin Zhang6,3;Mengpan Li1,3;Negar Javanmardi5;Hao Zhu7;Yu Wang5;Xin Yu2;Guangxin Zhou2;Jianda Xu8CA1;Jianning Zhao2CA2;Zhang-Qi Feng5CA3;Ting Wang6CA41Department of Orthopedic Oncology, Shanghai Bone Tumor Institute, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, PR China;2Department of Orthopedics, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210002, PR China;3Authors contributed equally to this work.;4Department of Vascular Surgery, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, 102218, PR China;5School of Chemistry and Chemical Engineering, Nanjing University of Science and Technology, Nanjing, 210094, PR China;6State Key Laboratory of Digital Medical Engineering, Southeast University, Nanjing, 210096, PR China;7School of Life Sciences, Nanjing University, Nanjing, 210033, Jiangsu, PR China;8Department of Orthopedics, Changzhou Hospital of Traditional Chinese Medicine, Changzhou Hospital Affiliated to Nanjing University of Chinese Medicine, Changzhou, 213003, PR China)

出处: Biomaterials 2026

关键词: Bionic electric signals;Bone regeneration;Metabolic reprogramming;Self-sustained bioelectronic system.

摘要: Bionic bioelectronics has promising applications in bone defect repair, with current research primarily focusing on the development of electroactive b ...

作者: Xixi Hou1,2;Shuxiang Xu3CA1;Longfei Mao4,5;Yue-Ming Li5;Jianji Wang1CA21Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan 453007, P.R. China;2The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Henan 471003, P.R. China;3Department of Laboratory Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, P.R. China;4College of Basic Medicine and Forensic Medicine, Henan University of Science and Technology, Henan 471000, P.R. China;5State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Haihe Education Park, 38 Tongyan Road, Tianjin 300350, P.R. China)

出处: Bioorganic & Medicinal Chemistry Letters 2026

关键词: 1,2,3-Triazole;Antitumor;DNA damage;Prostate Cancer cells;Stanolone.

摘要: 1,2,3-Triazole skeleton may act as both a hydrogen bond acceptor and a linker connecting different structures, and androgens bearing 1,2,3-triazole st ...

作者: Yanrui Jin1,2CA1;Mengxiao Wang1,2;Zhiyuan Li1,2;Yuanyuan Tian1,2;Xiaoyang Wei1,2;Chengliang Liu1,2CA2;Liqun Zhao3CA31State Key Laboratory of Mechanical System and Vibration, School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai, China;2MoE Key Lab of Artificial Intelligence, AI Institute, Shanghai Jiao Tong University, Shanghai, China;3Department of cardiology, Shanghai General Hospital, Shanghai, China)

出处: Biomedical Signal Processing and Control 2026

摘要: Timely intelligent diagnosis of arrhythmias is of great significance in controlling cardiovascular diseases. The application of artificial intelligenc ...

作者: Rulin Zhang1,2,3;Haonan Ma4,3;Yiting Yang5,3;Siang Lv1,6,7;Xin Guan1;Bingnan Lu8;Yuntao Yao8;Runzhi Huang9;Yifan Liu8CA1;Yanhua Du10CA2;Jun Wu1,6,7CA31Department of Laboratory Medicine, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201803, China;2Department of Laboratory Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China;3These authors contributed equally to this work and shared the first authorship.;4Department of Ophthalmology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China;5Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China;6Department of Pathology, The Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi 533000, China;7Key Laboratory of Tumor Molecular Pathology of Guangxi Higher Education Institutes, Baise, Guangxi 533000, China;8Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China;9Department of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai 200433, China;10Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China)

出处: Genes & Diseases 2026

作者: Jihong Jiang1,2;Yi Wu3,2;Xiaoyu Shang1,3,2;Meiru Jiang1;Liping Zhu1;Dongmei Hong1,3CA1;Enduo Feng4CA2;Guanghui An1,4CA31Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China;2These authors contributed equally.;3Department of Nursing, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China;4Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center for Anesthesiology and Perioperative Medicine, Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, Shanghai, 200434, China)

出处: Sensors and Actuators B: Chemical 2026

摘要: Propofol remains the first sedative choice due to its rapid onset and short distribution half-life. However, the narrow therapeutic window and pronoun ...

作者: Tong Li MD, PhD1,2,3,4,5,6;Shiqi Yang MD, PhD1,2,3,4,5,6;Qinghuai Liu MD7,3,4,5,6;Yanping Song MS8,3,4,5,6;Jianping Tong MD9,3,4,5,6;Wenbin Wei MD10,3,4,5,6;Weiqi Chen BS11,3,4,5,6;Hong Dai MD12,3,4,5,6;Wei Wang MS13,3,4,5,6;Miaoqin Wu MD14,3,4,5,6;Guohong Zhou MD15,3,4,5,6;Xuan Xiao MD16,3,4,5,6;Jinglin Zhang MD17,3,4,5,6;Rongrong Zhu MS18,3,4,5,6;Haoyu Li MS19,3,4,5,6;Yafang Wang PhD19,3,4,5,6;Xiaoyu Chen PhD19,3,4,5,6;Shujie Lu MS19,3,4,5,6;Haiwei Du PhD19,3,4,5,6;Han Han-Zhang PhD19,3,4,5,61Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;2T.L. and S.Y. contributed to this study equally.;3Department of Ophthalmology, Huai'an First People's Hospital, Huai'an, China;4Department of Fundus Diseases and Surgery, The Affiliated Eye Hospital of Shandong University of Chinese Medicine, Jinan, China;5Department of Ophthalmology, The First Bethune Hospital of Jilin University, Changchun, China;6Department of Fundus, Weifang Eye Hospital, Weifang, China;7Department of Ophthalmology, The First Affiliated Hospital With Nanjing Medical University, Nanjing, China;8Department of Ophthalmology, General Hospital of Central Theater Command of PLA, Wuhan, China;9Department of Ophthalmology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China;10Department of Ophthalmology, Beijing Tongren Hospital Affiliated to Capital Medical University, Beijing, China;11Department of Fundus, Joint Shantou International Eye Center of Shantou University and The Chinese University of Hongkong, Shantou, China;12Department of Ophthalmology, Beijing Hospital, Beijing, China;13Department of Diabetic Eye Diseases, Hebei Eye Hospital, Xingtai, China;14Department of Ophthalmology, Zhejiang Provincial People's Hospital, Hangzhou, China;15Department of Fundus, Shanxi Eye Hospital, Taiyuan, China;16Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, China;17Department of Fundus, Guangzhou Aier Eye Hospital, Guangzhou, China;18Department of Ophthalmology, Affiliated Hospital of Nantong University, Nantong, China;19Department of General Biomedicine, Innovent Biologics Co.. Ltd., Suzhou, China)

出处: Ophthalmology Science 2026

关键词: IBI302;VEGF;Complement;nAMD

摘要: Purpose This study aims to evaluate the efficacy and safety of high-dose efdamrofusp alfa (IBI302, targeting VEGF and complement C3b/4b) with personal ...

作者: Dichao Hu1,2;He Liu1,2;Mingyang Li1,2;Zekun Jiang3;Wenbo Wu1;Minghui Sun1;Wei Shen3CA1;Mingmin Liu4CA2;Haitao Liu1CA31Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No.100, Haining Road, Shanghai 200080, China;2These authors equally contributed to this work.;3Ministry of Education (MoE) Key Lab of Artificial Intelligence, Artificial Intelligence (AI) Institute, Shanghai Jiao Tong University, Shanghai 200080, China;4Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No.100, Haining Road, Shanghai 200080, China)

出处: Biomedical Signal Processing and Control 2026

关键词: Medical image semantic segmentation;Few-slice-annotated;Entropy optimization;Cross supervision

摘要: Purpose We designed a semi-supervised method that effectively utilized few-slice-annotated data for efficient MRI segmentation. Methods We investigate ...

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