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作者: Haiming Zheng #  1, Meiying Zhu #  1, Wenhua Li  2, Zunqiang Zhou  3, Xinjian Wan  1 (Affiliations 1 Digestive Endoscopic Center, Shanghai Jiao Tong University Affiliated Sixth People\'s Hospital. 2 Department of Gastroenterology, Jiading Branch of Shanghai General Hospital, Shanghai JiaoTong University School of Medicine. 3 Department of Surgery, Shanghai Jiao Tong University Affiliated Sixth People\'s Hospital.)

出处: Liver international : official journal of the International Association for the Study of the Liver 2022

关键词: METTL3;NSUN2;RNA methylation;YAP1;ceRNA.

摘要: Cholangiocarcinoma (CCA) is a severe malignancy originating from the bile duct and the second most common primary liver cancer. NF-kappa B interacting ...

作者: Kaige Ma  1, Donghua Huang  1, Chunqing Meng  1, Hong Wang  1, Zengwu Shao  1, Huimin Liu  2, Dehao Fu  1   3 (Affiliations 1 Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China (mainland). 2 Department of Internal Emergency Medicine, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China (mainland). 3 Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China (mainland).)

出处: Medical science monitor : international medical journal of experimental and clinical research 2022 Vol.28 Pe934488

摘要: BACKGROUND Open distal humeral fractures (DHFs) often lead to loss of elbow function, thereby seriously affecting patient quality of life. The aim of ...

作者: Louis Wing-Cheong Chow  1   2, Pei-Fen Fu  3, Lei Guo  4, Xi-Chun Hu  5, Jun Jiang  6, Erich Ferdiansyah Lie  1, Jian Liu  7, Xiao-Hong Lu  2, Yong-Kui Lu  8, Hong-Min Ma  9, Qin-Guo Mo  10, Yan-Xia Shi  11, Kun Wang  12   13, Ming-Hao Wang  6, Shu Wang  14, Shu-Sen Wang  15, Xian-Ming Wang  16, Xiao-Jia Wang  17, Hui-Jing Wu  18, Hong-Jian Yang  19, He-Rui Yao  20, Yi Zhang  6, Li Zhu  21, - On Behalf Of The Asian Institute Of Clinical Oncology Aico Expert Panel (Affiliations 1 UNIMED Medical Institute, Hong Kong SAR, China. 2 Organisation for Oncology and Translational Research, Hong Kong SAR, China. 3 Department of Breast Surgery, The First Affiliated Hospital, Zhejiang University, Hangzhou, China. 4 Department of Burn and Plastic Surgery, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China. 5 Department of Medical Oncology, Fudan University Shanghai Cancer Center, Xuhui District, Shanghai, China. 6 Breast Disease Centre, Southwest Hospital, Third Military Medical University, Chongqing, China. 7 Department of Breast Medical Oncology, Fujian Provincial Tumor Hospital, Fuzhou, China. 8 The Department of Breast and Bone Tissue Oncology, Affiliated Tumor Hospital of Guangxi Medical University, China. 9 Department of Breast Surgery, Guangzhou Women and Children\'s Medical Center, Guangzhou, China. 10 Department of Breast Surgery, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, China. 11 Department of Medical Oncology, Sun Yat-sen University Cancer Center, Guangzhou, China. 12 Department of Breast Cancer, Cancer Center, Guangdong Provincial People\'s Hospital and Guangdong Academy of Medical Sciences, Guangzhou, China. 13 The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China. 14 Breast Center, Peking University People\'s Hospital, Beijing, China. 15 Department of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, China. 16 Department of Thyroid and Breast Surgery, Shenzhen Second People\'s Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, China. 17 Department of Breast Medical Oncology, Cancer Hospital of the University of Chinese Academy of Sciences / Zhejiang Cancer Hospital/Institute of Cancer and Basic Medicine (ICBM), Chinese Academy of Sciences, Hangzhou, China. 18 Department of Medical Oncology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. 19 Department of Breast Surgery, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang, China. 20 Department of Oncology, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou, China. 21 Department of Thyroid and Breast Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.)

出处: Asian Pacific journal of cancer prevention : APJCP 2022 Vol.23 No.2 P379-382

关键词: China;Questionnaire;breast cancer;perceived importance;risk factor.

摘要: There are varying definitions of women at high risk of breast cancer across different institutions, and there are reports suggesting that the breast c ...

作者: Tao Zhang  1, Suoyuan Li  2, Jingjie Li  3, Fei Yin  4, Yingqi Hua  4, Zhuoying Wang  4, Hongsheng Wang  4, Dongqing Zuo  4, Jing Xu  4, Zhengdong Cai  5 (Affiliations 1 Department of Orthopedics, Shanghai Bone Tumor Institution, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, PR China. Electronic address: zhangtaoabc@2008.sina.com. 2 Department of Orthopedics, Shanghai Bone Tumor Institution, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, PR China; Suzhou Municipal Hospital, Suzhou, PR China. 3 Translational Medicine Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, PR China. 4 Department of Orthopedics, Shanghai Bone Tumor Institution, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, PR China. 5 Department of Orthopedics, Shanghai Bone Tumor Institution, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, PR China. Electronic address: caizhengdong@sjtu.edu.cn.)

出处: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022

关键词: Metastasis;Osteosarcoma;Pectolinarigenin;SHP-1;STAT3 signaling.

摘要: Signal transducer and activator of transcription 3 (STAT3) plays essential roles in cancer progression and has been considered as a promising target f ...

作者: Lin Ding  1, Jie Li  2, Xue Li  3, Bingqian Qu  4   5 (Affiliations 1 Department of Cardiology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200240, China. 2 Department of Basic Medical Sciences & Forensic Medicine, Hangzhou Medical College, Hangzhou 310059, China. 3 Department of Internal Medicine III, University Hospital Heidelberg, 69120 Heidelberg, Germany. 4 Department of Veterinary Medicine, Paul Ehrlich Institute, 63225 Langen, Germany. 5 European Virus Bioinformatics Center (EVBC), 07743 Jena, Germany.)

出处: Pathogens (Basel, Switzerland) 2022

关键词: H5N8;evolution;high pathogenic avian influenza;human transmission;influenza A virus;mutation;phylogenetic analysis;tMRCA.

摘要: Highly pathogenic influenza A virus H5 subtype remains a risk for transmission in humans. The H5N8 subtype has caused multiple outbreaks in poultry in ...

作者: Yiting Gui  1, Yawen Zhang  1, Qi Zhang  2, Xudong Chen  2, Feng Wang  1, Fang Wu  3, Yonghao Gui  4, Qiang Li  5 (Affiliations 1 Translational Medical Center for Development and Disease, Shanghai Key Laboratory of Birth Defect, Institute of Pediatrics, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai 201102, China; Cardiovascular Center, NHC Key Laboratory of Neonatal Diseases, Fudan University, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai 201102, China. 2 Translational Medical Center for Development and Disease, Shanghai Key Laboratory of Birth Defect, Institute of Pediatrics, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai 201102, China. 3 Translational Medical Center for Development and Disease, Shanghai Key Laboratory of Birth Defect, Institute of Pediatrics, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai 201102, China; Department of Neonatology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201600, China. 4 Translational Medical Center for Development and Disease, Shanghai Key Laboratory of Birth Defect, Institute of Pediatrics, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai 201102, China; Cardiovascular Center, NHC Key Laboratory of Neonatal Diseases, Fudan University, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai 201102, China. Electronic address: yhgui@fudan.edu.cn. 5 Translational Medical Center for Development and Disease, Shanghai Key Laboratory of Birth Defect, Institute of Pediatrics, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai 201102, China. Electronic address: liq@fudan.edu.cn.)

出处: Cells & development 2022

关键词: Cis-regulatory regions;ECR;Fugu;Promoter;TNNI1 (troponin I1);Zebrafish.

摘要: Troponin I type 1b (Tnni1b) is thought to be a novel isoform that is expressed only in the zebrafish heart. Knocking down of tnni1b can lead to cardia ...

作者: Guoliang Wang  1, Dan Bing  2, Xinwei Chen  1, Pin Dong  1 (Affiliations 1 Department of Otolaryngology Head and Neck Surgery,Nanjing Medical University of Shanghai General Hospital,Shanghai,200080,China. 2 Department of Otolaryngology Head and Neck Surgery,Tongji Hospital of Huazhong University of Science and Technology.)

出处: Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery 2022

关键词: airway;curved hard tube visual laryngoscope;surgical procedures,operative;vocal cord polyps.

摘要: Objective:To test the feasibility of a rigid curved video laryngoscope in laryngeal microsurgery of patients with difficult laryngeal exposure. Method ...

作者: Yezhe Lin  1, Alexander D Zhang  1, Ching-Fang Sun  1, Justin B White  1, Ansi Qi  1, Jessica A Farrell  1, Robert L Trestman  1, Rachel K Martin  1, Anita S Kablinger  1 (Affiliation 1 Lin, MD, Sun, MD, White, MD, Farrell, MD, Trestman, MD, Martin, MD, Kablinger, MD, Department of Psychiatry and Behavioral Science, Carilion Clinic-Virginia Tech Carilion School of Medicine, Roanoke, VA, USA; Virginia Tech Carilion School of Medicine, Roanoke, VA, USA. Zhang, BA, Virginia Tech Carilion School of Medicine, Roanoke, VA, USA. Qi, MD, Department of Medical Psychology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China.)

出处: Psychopharmacology bulletin 2022

关键词: buprenorphine;mania;psychosis;substance-withdrawal;two-hit hypothesis.

摘要: Buprenorphine and naloxone (Suboxone) is a combination medication-assisted treatment (MAT) for opioid use disorder. MAT withdrawal-induced psychosis i ...

作者: Yiting Gui1,2,3;Yawen Zhang1,2,3;Qi Zhang1;Xudong Chen1;Feng Wang1,2;Fang Wu4;Yonghao Gui2CA1;Qiang Li1CA21Translational Medical Center for Development and Disease, Shanghai Key Laboratory of Birth Defect Prevention and Control, NHC Key Laboratory of Neonatal Diseases, Institute of Pediatrics, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai 201102, China;2Cardiovascular Center, NHC Key Laboratory of Neonatal Diseases, Fudan University, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai 201102, China;3These authors contributed equally to this work.;4Department of Neonatology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201600, China)

出处: Cells & Development 2022

关键词: Cis-regulatory regions;Promoter;Fugu;ECR;TNNI1 (troponin I1);Zebrafish

摘要: Troponin I type 1b (Tnni1b) is thought to be a novel isoform that is expressed only in the zebrafish heart. Knocking down of tnni1b can lead to cardia ...

作者: Xiaomin Xu1;Zongshan Li2;Huirong Zuo3;Huimin Chen2;Yaxing Gui1,2CA11Department of Neurology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310016, China;2Department of Neurology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China;3Department of Rehabilitation Medicine, Haining Kanghua Hospital, Jiaxing, Zhejiang 314419, China)

出处: Neuroscience Letters 2022

关键词: Exosomes;Cholesterol;Lipid raft;Parkinson’s disease

摘要: Parkinson’s disease (PD) is associated with abnormal metabolism of brain cholesterol, and the metabolites of neuronal cholesterol may also affect neur ...

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