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作者: Zhichao Tong  1   2   3   4, Yubo Zhao  1   2, Shiyu Bai  2   4, Benedikt Ebner  3   5, Lou Lienhard  3, Yuling Zhao  3, Ziqi Wang  1   2, Qi Pan  3   6, Pengyu Guo  1   2, Thilo Bracht  7   8, Barbara Sitek  7   8, Jürgen E Gschwend  3, Wanhai Xu  1   2, Roman Nawroth  3 (Affiliations 1 Department of Urology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, P. R. China. 2 NHC and CAMS Key Laboratory of Molecular Probe and Targeted Theranostics, Harbin Medical University, Harbin, Heilongjiang, P. R. China. 3 Department of Urology, Klinikum rechts der Isar, Technical university of Munich, Munich, Germany. 4 Department of Urology, The Fourth Hospital of Harbin Medical University, Harbin, Heilongjiang, P. R. China. 5 Department of Urology, Ludwig-Maximilians-University of Munich, Munich, Germany. 6 Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, P. R. China. 7 Medizinisches Proteom-Center, Ruhr-Universität Bochum, Bochum, Germany. 8 Clinic for Anesthesiology, Intensive Care and Pain Therapy, University Medical Center Knappschaftskrankenhaus Bochum, Bochum, Germany.)

出处: Cancer communications (London, England) 2024

作者: Jie Mei  1   2, Yun Cai  3, Rui Xu  1   2, Qing Li  4, Jiahui Chu  1   2, Zhiwen Luo  5, Yaying Sun  6, Yuxin Shi  7, Junying Xu  7, Di Li  8, Shuai Liang  7, Ying Jiang  9, Jiayu Liu  9, Zhiwen Qian  3, Jiaofeng Zhou  10, Mengyun Wan  10, Yunlong Yang  11, Yichao Zhu  10, Yan Zhang  3   9, Yongmei Yin  1   12 (Affiliations 1 Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, P. R. China. 2 The First Clinical Medicine College, Nanjing Medical University, Nanjing, Jiangsu, P. R. China. 3 Departments of Gynecology, Wuxi Maternal and Child Health Care Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu, P. R. China. 4 Departments of Oncology, Xuzhou Central Hospital, The Xuzhou School of Clinical Medicine of Nanjing Medical University, Xuzhou, Jiangsu, P. R. China. 5 Department of Sports Medicine, Huashan Hospital Affiliated to Fudan University, Shanghai, P. R. China. 6 Department of Sports Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China. 7 Departments of Oncology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu, P. R. China. 8 Shanghai Outdo Biotech Co., Ltd., National Engineering Center for Biochip, Shanghai, P. R. China. 9 Departments of Gynecology, Wuxi Maternity and Child Health Care Hospital, Affiliated Women's Hospital of Jiangnan University, Wuxi, Jiangsu, P. R. China. 10 Department of Physiology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, Jiangsu, P. R. China. 11 Department of Cellular and Genetic Medicine, School of Basic Medical Sciences, Fudan University, Shanghai, P. R. China. 12 Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Personalized Cancer Medicine, Nanjing Medical University, Nanjing, Jiangsu, P. R. China.)

出处: Cancer communications (London, England) 2024

关键词: collagen deposition;immune infiltration;immunotherapy;pan‐cancer;tumor microenvironment.

摘要: Background: Immune checkpoint blockade (ICB) has revolutionized the treatment of various cancer types. Despite significant preclinical advancements in ...

作者: X G He  1 (Affiliation 1 Shanghai Eye Disease Prevention and Treatment Center, Tongji University Affiliated Eye Hospital, Shanghai General Hospital of Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai 201103, China.)

出处: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 2024

摘要: The International Myopia Institute introduced the concept of 'pre-myopia' in 2019, defining it as children with refractive error ≤+0.75 D and >-0.50 D ...

作者: Su Feng  1, Ting Zhang  2   3   4, Zhengxiao He  1, Wenchang Zhang  1, Yingying Chen  1, Chunmei Yue  5, Naihe Jing  6 (Affiliations 1 Guangzhou National Laboratory, Guangzhou, 510005, China. 2 Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. 3 National Clinical Research Center for Eye Disease, Shanghai, 200080, China. 4 Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai, 200080, China. 5 Suzhou Yuanzhan Biotechs, Suzhou, 215000, China. 6 Guangzhou National Laboratory, Guangzhou, 510005, China. njing@sibcb.ac.cn.)

出处: Cell regeneration (London, England) 2024

关键词: Cell transplantation;Human induced neural stem/progenitor cells (iNPCs);Immune response;Non-human primate brain;Xenograft.

摘要: Continuous immunosuppression has been widely used in xenografts into non-human primate brains. However, how immune responses change after transplantat ...

作者: Chen Jin  1   2, Kaiwei Wang  1, Yilong Ren  1   3, Yi Li  1, Zhanwei Wang  1, Liming Cheng  1, Ning Xie  1 (Affiliations 1 Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration of Ministry of Education Orthopaedic Department of Tongji Hospital School of Medicine Tongji University Shanghai China. 2 Department of Orthopedics Tongren Hospital Shanghai Jiaotong University School of Medicine Shanghai China. 3 Department of Orthopedics Shanghai General Hospital Shanghai Jiaotong University School of Medicine Shanghai China.)

出处: MedComm 2024

关键词: Spinal cord injury;decompression;durotomy;functional recovery;secondary injuries.

摘要: Currently, there is a lack of effective treatments for spinal cord injury (SCI), a debilitating medical condition associated with enduring paralysis a ...

作者: Jie Jiang  1, Zai Luo  1, Hao-Liang Zhang  1, Zheng-Jun Qiu  1, Chen Huang  1 (Affiliation 1 Department of Gastrointestinal Surgery,Shanghai General Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200080,China.)

出处: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 2024

关键词: circular RNA;internal ribosome entry site;protein;protein bait.

摘要: Circular RNAs(CircRNAs)are a class of non-coding RNAs with a covalently closed-loop structure,high stability,and tissue specificity,with the productio ...

作者: Xiaorui Cao  1, Linli Xue  1, Xiuju Yu  1, Yi Yan  1, Jiayin Lu  1, Xiaomao Luo  1, Haidong Wang  1, Juan Wang  1   2 (Affiliations 1 College of Veterinary Medicine, Shanxi Agricultural University, Taigu, Shanxi 030801, China. 2 Department of Nephrology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200080, China.)

出处: Aging 2024

关键词: exosomes;miR-140-5p;muscle injury repair;muscle satellite cells;regeneration.

摘要: Muscle satellite cells (SCs) play a crucial role in the regeneration and repair of skeletal muscle injuries. Previous studies have shown that myogenic ...

作者: Hongwei Shi  1, Xiaojing Hao  1, Yaqin Sun  1, Yating Zhao  1, Yue Wang  1, Xiaorui Cao  1, Zeen Gong  1, Shusen Ji  1, Jiayin Lu  1, Yi Yan  1, Xiuju Yu  1, Xiaomao Luo  1, Juan Wang  2, Haidong Wang  1 (Affiliations 1 College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong, P.R. China. 2 Department of Nephrology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, P.R. China.)

出处: Acta physiologica (Oxford, England) 2024

关键词: AMPK;browning;exercise;extracellular vesicle;integrin αV;irisin.

摘要: Aim: Exercise can reduce body weight and promote white fat browning, but the underlying mechanisms remain largely unknown. This study investigated the ...

作者: Shengzhou Li  1, Yiming Chen  2, Xiangqian Cao  1, Chenkai Yang  1, Wei Li  3, Bing Shen  1   4 (Affiliations 1 Department of Urology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 200080, Shanghai, China. 2 Department of Orthopedics, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 200080, Shanghai, China. 3 Department of Nanomedicine & Shanghai Key Lab of Cell Engineering, Naval Medical University, 200433, Shanghai, China. 4 Shanghai Tenth People's Hospital of Tongji University, 200072, Shanghai, China.)

出处: Nanomedicine (London, England) 2024

关键词: graft function evaluation;immunosuppressants;kidney transplantation;nanotechnology;organ preservation.

摘要: Kidney transplantation is a crucial treatment option for end-stage renal disease patients, but challenges related to graft function, rejection and imm ...

作者: S Y Zhao  1, H M Liu  2, Q Lu  3, X C Liu  1, J G Hong  4, E M Liu  5, Y X Zou  6, M Yang  7, Z M Chen  8, H L Zhang  9, D Y Zhao  10, X B Zhang  11, Y Yin  12, X Y Dong  3, X X Lu  13, J R Liu  1, L N Chen  2 (Affiliations 1 Department of No.2 Respiratory Medicine, Beijing Children's Hospital, Capital Medical University, National Clinical Research Center for Respiratory Diseases, National Center for Children's Health, Beijing 100045, China. 2 Department of Pediatric Pulmonology and Immunology, West China Second University Hospital, Sichuan University, Chengdu 610041, China. 3 Department of Pulmonology, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200062, China. 4 Department of Pediatrics, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai 200080, China. 5 Department of Respiratory, Children's Hospital of Chongqing Medical University, Chongqing 400014, China. 6 Department of Pulmonology, Tianjin Children's Hospital (Children's Hospital of Tianjin University), Machang Compus, Tianjin 300074, China. 7 Department of Pharmacy, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China. 8 Department of Pulmonology, Children's Hospital, Zhejiang University School of Medicine, Hangzhou 310052, China. 9 Department of Pediatric Respiratory Medicine, the Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325027, China. 10 Department of Respiratory Medicine, Children's Hospital of Nanjing Medical University, Nanjing 210008, China. 11 Department of Respiratory Disease, Children's Hospital of Fudan University, Shanghai 201102, China. 12 Department of Respiratory Medicine, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai 200062, China. 13 Department of Respiratory Medicine, Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430015, China.)

出处: Zhonghua er ke za zhi = Chinese journal of pediatrics 2024

摘要: 2023年肺炎支原体肺炎(MPP)在全国流行,国家卫生健康委员会于2023年2月发布“儿童肺炎支原体肺炎诊治指南”,但在实施过程中仍需要根据目前MPP特点,对重要诊治环节更加具体地指导和建议,现对MPP早期诊断方法、重症MPP判断依据和预警指标、各类抗支原体药物适应证、大环内酯类药物无反应性处理原则 ...

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