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作者: Weilin Sang #  1, Peng Lai #  1, Xun Xu  1, Yu Liu  1, Jinzhong Ma  2, Libo Zhu  3 (Affiliations 1 Department of Orthopaedics, Shanghai General Hospital, Shanghai, 201620, China. 2 Department of Orthopaedics, Shanghai General Hospital, Shanghai, 201620, China. majinzhong007@163.com. 3 Department of Orthopaedics, Shanghai General Hospital, Shanghai, 201620, China. libozhu2018@163.com.)

出处: Arthroplasty (London, England) 2024

关键词: Arthroplasty;Component positioning;Direct anterior approach;Hip.

摘要: Background: Controversy remains over whether different surgical approaches exert an impact on the component positioning in total hip arthroplasty. We ...

作者: Yanmei Yuan  1, Junting Xu  1, Quanxin Jiang  1, Chuanxin Yang  1, Ning Wang  1, Xiaolong Liu  2, Hai-Long Piao  2, Sijia Lu  1, Xianjing Zhang  1, Liu Han  1, Zhiyan Liu  3, Jiabin Cai  4, Fang Liu  5, Suzhen Chen  6, Junli Liu  7 (Affiliations 1 Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China. 2 Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China. 3 Department of Pathology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China. 4 Department of Liver Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Zhongshan Hospital, Shanghai, 200032, China. cai.jiabin@zs-hospital.sh.cn. 5 Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. f-liu@sjtu.edu.cn. 6 Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China. cszdream@163.com. 7 Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China. liujunli@sjtu.edu.cn.)

出处: Journal of experimental & clinical cancer research : CR 2024

关键词: De novo lipogenesis;Ferroptosis;Ficolin 3;Insulin receptor;MUFA.

摘要: Background: Targeting ferroptosis has been identified as a promising approach for the development of cancer therapies. Monounsaturated fatty acid (MUF ...

作者: Jiaqiang Ma #  1, Yingcheng Wu #  1, Lifeng Ma #  2, Xupeng Yang #  1, Tiancheng Zhang #  1, Guohe Song  1, Teng Li  3, Ke Gao  1, Xia Shen  1, Jian Lin  1, Yamin Chen  3, Xiaoshan Liu  3, Yuting Fu  2, Xixi Gu  3, Zechuan Chen  3, Shan Jiang  3, Dongning Rao  1, Jiaomeng Pan  1, Shu Zhang  1, Jian Zhou  1, Chen Huang  4, Si Shi  5, Jia Fan  1, Guoji Guo  2, Xiaoming Zhang  3, Qiang Gao  1 (Affiliations 1 Department of Liver Surgery and Transplantation, and Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China. 2 Center for Stem Cell and Regenerative Medicine, Zhejiang University School of Medicine, and Stem Cell Institute, Zhejiang University, Hangzhou 310058, China. 3 The Center for Microbes, Development and Health, Key Laboratory of Immune Response and Immunotherapy, Shanghai Institute of Immunity and Infection, Chinese Academy of Sciences, Shanghai 200031, China. 4 Department of Gastrointestinal Surgery, Shanghai General Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200080, China. 5 Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, China.)

出处: Science (New York, N.Y.) 2024

摘要: B lymphocytes are essential mediators of humoral immunity and play multiple roles in human cancer. To decode the functions of tumor-infiltrating B cel ...

作者: Angela C C Jochems  1   2, Susana Muñoz Maniega  1   2, Francesca M Chappell  1   2, Una Clancy  1   2, Carmen Arteaga  1   2, Daniela Jaime Garcia  1   2, Olivia K L Hamilton  1   2   3, Will Hewins  1   2, Rachel Locherty  1   2, Ellen V Backhouse  1   2, Gayle Barclay  1   4, Charlotte Jardine  1   4, Donna McIntyre  1   4, Iona Gerrish  1   4, Yajun Cheng  1   2   5, Xiaodi Liu  1   2   6, Junfang Zhang  1   2   7, Agniete Kampaite  1, Eleni Sakka  1, Maria Valdés Hernández  1   2, Stewart Wiseman  1   2, Michael S Stringer  1   2, Michael J Thrippleton  1   2   4, Fergus N Doubal  1   2, Joanna M Wardlaw  1   2   4 (Affiliations 1 Centre for Clinical Brain Sciences, University of Edinburgh, EH16 4SB Edinburgh, United Kingdom. 2 MRC UK Dementia Research Institute at the University of Edinburgh, EH16 4SB Edinburgh, United Kingdom. 3 MRC/CSO Social and Public Health Sciences Unit, School of Health and Wellbeing, University of Glasgow, G12 8TB Glasgow, United Kingdom. 4 Edinburgh Imaging Facility, Royal Infirmary of Edinburgh, EH16 4TJ Edinburgh, United Kingdom. 5 Department of Neurology, West China Hospital of Sichuan University, 610041 Chengdu, China. 6 Department of Medicine, LKS Faculty of Medicine, University of Hong Kong, Hong Kong, China. 7 Department of Neurology, Shanghai General Hospital, Shanghai Jiao Tong University School of medicine, 200080 Shanghai, China.)

出处: Brain communications 2024

关键词: dexterity;imaging;mobility;small vessel disease;white matter hyperintensity.

摘要: White matter hyperintensities (WMH), a common feature of cerebral small vessel disease, are related to worse clinical outcomes after stroke. We assess ...

作者: Da Lu  1   2, Jiajia Fan  3, Yang Lin  4, Kai Yang  5, Fuzhen Zheng  6, Teng Ma  2, Feng Zhu  2 (Affiliations 1 Department of Thoracic-Cardiac Surgery, Hubei Provincial Hospital of Traditional Chinese Medicine, Affiliated Hospital of Hubei University of Chinese Medicine, Wuhan. 2 Department of Vascular Surgery, General Surgery Clinical Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai. 3 Community Health Service Center of Caoyang Street, Putuo District, Shanghai. 4 Department of Cardiovascular Surgery, Gaozhou Hospital, Gaozhou. 5 Community Health Service Center of Zhoujiaqiao Street, Changning District, Shanghai. 6 Department of Cardiovascular Surgery, Shengli Clinical Medical College of Fujian Medical University, Fujian Medical University, Fuzhou, People's Republic of China.)

出处: Annals of medicine and surgery (2012) 2024

关键词: IL-4;macrophage polarization;myocardial infarction.

摘要: IL-4, an immunoregulatory cytokine, plays a role in various cellular pathways and is known to regulate M2 macrophage polarization. Numerous studies ha ...

作者: Xiangxiao Li  1   2, Fengjiao Zhang  1, Libo Sun  1, Xiaojie Cai  1, Fangzhou Lou  1, Yang Sun  1, Min Gao  1, Zhikai Wang  1, Sibei Tang  1, Li Fan  1, Yue Wu  1, Xinping Jin  1, Siyu Deng  1, Zhenyao Xu  1, Xuxu Sun  2, Qun Li  3, Honglin Wang  1 (Affiliations 1 Precision Research Center for Refractory Diseases, Institute for Clinical Research, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 Department of Biochemistry and Molecular Cell Biology, State Key Laboratory of Systems Medicine for Cancer, Shanghai Key Laboratory for Tumor Microenvironment and Inflammation, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 3 Department of Cardiovascular Medicine, State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai, China.)

出处: Journal of immunology (Baltimore, Md. : 1950) 2024

摘要: Psoriasis is a common inflammatory skin disorder with no cure. Mesenchymal stem cells (MSCs) have immunomodulatory properties for psoriasis, but the t ...

作者: Zhongjun Tang #  1   2   3   4, Xiaoxue Zhang #  5, Chiwen Cheng #  5, Yupeng Xu  6, Guoying Deng  7, Xingtao Zhou  8   9   10, Shengtao Liu  11   12   13 (Affiliations 1 Department of Ophthalmology, Minhang Hospital, Fudan University, Shanghai, 201100, China. 2 Department of Ophthalmology and Optometry, Eye and ENT Hospital, Fudan University, Shanghai, China. 3 Key Laboratory of Myopia, NHC Key Laboratory of Myopia (Fudan University), Chinese Academy of Medical Sciences, Shanghai, 200031, China. 4 Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China. 5 The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China. 6 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. 7 Trauma Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 650 Xin Songjiang Road, Shanghai, 201620, China. 8 Department of Ophthalmology and Optometry, Eye and ENT Hospital, Fudan University, Shanghai, China. doctzhouxingtao@163.com. 9 Key Laboratory of Myopia, NHC Key Laboratory of Myopia (Fudan University), Chinese Academy of Medical Sciences, Shanghai, 200031, China. doctzhouxingtao@163.com. 10 Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China. doctzhouxingtao@163.com. 11 Department of Ophthalmology and Optometry, Eye and ENT Hospital, Fudan University, Shanghai, China. 282985766@qq.com. 12 Key Laboratory of Myopia, NHC Key Laboratory of Myopia (Fudan University), Chinese Academy of Medical Sciences, Shanghai, 200031, China. 282985766@qq.com. 13 Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China. 282985766@qq.com.)

出处: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2024

关键词: Asthenopia;Mental status;Prevalence;Risk factor.

摘要: Background: The purpose of this study was to identify the possible association between mental status and the risk of self-reported asthenopia among co ...

作者: Shu Sun  1, Lei Cao  2, Jinglei Wu  1, Binbin Sun  3, Mohamed El-Newehy  4, Meera Moydeen Abdulhameed  5, Xiumei Mo  1, Xinjian Yang  6, Hao Zheng  1 (Affiliations 1 Donghua University, Songjiang, Shanghai, Shanghai, 201620, CHINA. 2 Shanghai General Hospital, Songjiang, Shanghai, Shanghai, Shanghai, 201620, CHINA. 3 Bioengineering, Donghua University, 2999 N Renmin Rd., Shanghai, 201620, CHINA. 4 King Saud University, 7804 Street No. 18, Riyadh, Riyadh, 11362, SAUDI ARABIA. 5 Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia, Riyadh, 11451, SAUDI ARABIA. 6 East China University of Science and Technology, Xuhui, Shanghai, Shanghai, Shanghai, 200231, CHINA.)

出处: Biomedical materials (Bristol, England) 2024

关键词: Antimicrobial;Antimicrobial mechanism;Electrospinning;Nitrogen-fluoride compounds;Wound dressing.

摘要: N-chloro-N-fluorobenzenesulfonylamide (CFBSA), was a novel chlorinating reagent, which exhibits potential antibacterial activities. In this study, CFB ...

作者: Dapeng Zhou  1, Huan Wu  2, Lingbo Wang  3, Xuemei Wang  4, Shuyan Tang  5, Yiling Zhou  5, Jiaxiong Wang  6, Bangguo Wu  3, Jianan Tang  4, Xuehai Zhou  4, Shixiong Tian  3, Shuang Liu  1, Mingrong Lv  2, Xiaojin He  7, Li Jin  8, Huijuan Shi  4, Feng Zhang  9, Yunxia Cao  10, Chunyu Liu  11 (Affiliations 1 State Key Laboratory of Genetic Engineering, Human Phenome Institute, Zhangjiang Fudan International Innovation Center, Fudan University, Shanghai 200438, China; Institute of Medical Genetics and Genomics, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China. 2 Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, China; NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei, Anhui 230032, China; Key Laboratory of Population Health Across Life Cycle, Anhui Medical University, Ministry of Education of the People's Republic of China, Hefei, Anhui 230032, China. 3 Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism and Integrative Biology, Institute of Reproduction and Development, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200433, China. 4 Shanghai-MOST Key Laboratory of Health and Disease Genomics, NHC Key Lab of Reproduction Regulation, Shanghai Institute for Biomedical and Pharmaceutical Technologies, School of Pharmacy, Fudan University, Shanghai 200237, China. 5 Institute of Medical Genetics and Genomics, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China. 6 State Key Laboratory of Reproductive Medicine, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, Nanjing 215002, China; Suzhou Municipal Hospital, Suzhou, Nanjing 215002, China. 7 Reproductive Medicine Center, Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. 8 State Key Laboratory of Genetic Engineering, Human Phenome Institute, Zhangjiang Fudan International Innovation Center, Fudan University, Shanghai 200438, China. 9 State Key Laboratory of Genetic Engineering, Human Phenome Institute, Zhangjiang Fudan International Innovation Center, Fudan University, Shanghai 200438, China; Institute of Medical Genetics and Genomics, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China; Soong Ching Ling Institute of Maternity and Child Health, International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China. Electronic address: zhangfeng@fudan.edu.cn. 10 Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, China; NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei, Anhui 230032, China; Key Laboratory of Population Health Across Life Cycle, Anhui Medical University, Ministry of Education of the People's Republic of China, Hefei, Anhui 230032, China. Electronic address: caoyunxia6@126.com. 11 Soong Ching Ling Institute of Maternity and Child Health, International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China. Electronic address: liuchunyu@shsmu.edu.cn.)

出处: Journal of genetics and genomics = Yi chuan xue bao 2024

关键词: Acrosome;ICSI;MFSD6L;Male fertility;Oligoasthenoteratozoospermia.

摘要: Oligoasthenoteratozoospermia is an important factor affecting male fertility and has been found to be associated with genetic factors. However, there ...

作者: Jingliang He1,2,3;Fang Zheng1,2,3;Li Zhang1,2,3;Jiangxiong Cai4;Yoko Ogawa5;Kazuo Tsubota5,6;Shan Liu7,8;Xiuming Jin1,2,3CA11Eye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, China;2Zhejiang Provincial Key Laboratory of Ophthalmology, Zhejiang Provincial Clinical Research Center for Eye Diseases, China;3Zhejiang Provincial Engineering Institute on Eye Diseases, Hangzhou, Zhejiang, China;4School of Medicine, Zhejiang University, China;5Department of Ophthalmology, Keio University, School of Medicine, Tokyo, Japan;6Tsubota Laboratory, Inc., Tokyo, Japan;7Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China;8Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai, China)

出处: The Ocular Surface 2024

摘要: Purpose To investigate the global transcriptional landscape of lacrimal gland cell populations in the GVHD mouse model. Methods Single-cell RNA sequen ...

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