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作者: Qing Yang 1, Xiaoqiang Wang 1, Guoying Deng 2, Xingguang Tao 3, Qiugen Wang 4 (Affiliations 1 Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China. 2 Trauma center, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. 3 Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University, Qingpu District Central Hospital Shanghai, Shanghai, China. 4 Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China. wangqiugen@126.com.)

出处: European journal of orthopaedic surgery & traumatology : orthopedie traumatologie 2026

关键词: Capitellum fracture;Classification;Functional outcome;Radial head fracture;Treatment.

作者: Genbin Wu #  1, Xinmeng Jin #  1, Jinwei Chen  1, Zhongwei Sun  2, Peng Miao  1, Haifeng Zhang  3, Yinxian Yu  4 (Affiliations 1 Department of Orthopedic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200240, China. 2 Department of Orthopedic Surgery, Tongzhou District People's Hospital of Nantong, Jiangsu Province, Nantong, 226300, China. 3 Department of Orthopedic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200240, China. Zhanghaifeng12000@163.com. 4 Department of Orthopedic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200240, China. eastpool@sjtu.edu.cn.)

出处: Arthroplasty (London, England) 2026

关键词: Mechanical alignment;Perioperative varus deformity change;Unicompartmental knee arthroplasty.

摘要: Background: Although favorable survival and good outcomes have been reported with Oxford unicompartmental knee arthroplasty (UKA), the effect of perio ...

作者: Tong Li MD, PhD1,2,3,4,5,6;Shiqi Yang MD, PhD1,2,3,4,5,6;Qinghuai Liu MD7,3,4,5,6;Yanping Song MS8,3,4,5,6;Jianping Tong MD9,3,4,5,6;Wenbin Wei MD10,3,4,5,6;Weiqi Chen BS11,3,4,5,6;Hong Dai MD12,3,4,5,6;Wei Wang MS13,3,4,5,6;Miaoqin Wu MD14,3,4,5,6;Guohong Zhou MD15,3,4,5,6;Xuan Xiao MD16,3,4,5,6;Jinglin Zhang MD17,3,4,5,6;Rongrong Zhu MS18,3,4,5,6;Haoyu Li MS19,3,4,5,6;Yafang Wang PhD19,3,4,5,6;Xiaoyu Chen PhD19,3,4,5,6;Shujie Lu MS19,3,4,5,6;Haiwei Du PhD19,3,4,5,6;Han Han-Zhang PhD19,3,4,5,61Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;2T.L. and S.Y. contributed to this study equally.;3Department of Ophthalmology, Huai'an First People's Hospital, Huai'an, China;4Department of Fundus Diseases and Surgery, The Affiliated Eye Hospital of Shandong University of Chinese Medicine, Jinan, China;5Department of Ophthalmology, The First Bethune Hospital of Jilin University, Changchun, China;6Department of Fundus, Weifang Eye Hospital, Weifang, China;7Department of Ophthalmology, The First Affiliated Hospital With Nanjing Medical University, Nanjing, China;8Department of Ophthalmology, General Hospital of Central Theater Command of PLA, Wuhan, China;9Department of Ophthalmology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China;10Department of Ophthalmology, Beijing Tongren Hospital Affiliated to Capital Medical University, Beijing, China;11Department of Fundus, Joint Shantou International Eye Center of Shantou University and The Chinese University of Hongkong, Shantou, China;12Department of Ophthalmology, Beijing Hospital, Beijing, China;13Department of Diabetic Eye Diseases, Hebei Eye Hospital, Xingtai, China;14Department of Ophthalmology, Zhejiang Provincial People's Hospital, Hangzhou, China;15Department of Fundus, Shanxi Eye Hospital, Taiyuan, China;16Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, China;17Department of Fundus, Guangzhou Aier Eye Hospital, Guangzhou, China;18Department of Ophthalmology, Affiliated Hospital of Nantong University, Nantong, China;19Department of General Biomedicine, Innovent Biologics Co.. Ltd., Suzhou, China)

出处: Ophthalmology Science 2026

关键词: IBI302;VEGF;Complement;nAMD

摘要: Purpose This study aims to evaluate the efficacy and safety of high-dose efdamrofusp alfa (IBI302, targeting VEGF and complement C3b/4b) with personal ...

作者: Ruijun Cai1,2;Zhongnan Mao3,2;Tao An1;Yunbo Zhang4;Li Zhou1CA11Department of Pharmacy, Shanghai General Hospital Jiuquan Hospital (The People's Hospital of Jiuquan), Jiuquan, GanSu 735000, China;2These authors have contributed equally to this work and share first authorship;3Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou, GanSu 730000, China;4Gansu University of Chinese Medicine, Lanzhou, GanSu 730000, China)

出处: Journal of Chromatography B 2026

关键词: Byakangelicin;Metabolites;In vivo;UHPLC-Q-exactive orbitrap MS;Sprague-Dawley rats

摘要: Byakangelicin is a furanocoumarin derived from the roots of Angelica dahurica. It exhibits pharmacological properties, including anti-tumor activity, ...

作者: Yuan Liu1, Jian Sun1, Yanmei Hu1, Yu Wu1, Yixia Yang1 (Affiliation 1 Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.)

出处: Clinical and experimental reproductive medicine 2026

关键词: Birth weight;Estrogen vaginally;Frozen-thawed embryo transfer;Hormone replacement;Live birth.

摘要: Objective: Previous studies have reported a higher rate of small for gestational age (SGA) newborns from fresh embryo transfers compared with frozen-t ...

作者: Lingli Luo  1   2, Ling Liu  2, Minyao Deng  2, Yong Jiang  2, Chuan Liu  3, Xiang Chen  4, Xiaoxi Li  2 (Affiliations 1 Department of Infection Prevention and Control, Jiangxi Chest Hospital (Jiangxi Third People's Hospital), The Third Affiliated Hospital of Nanchang Medical College, Nanchang, China. 2 Department of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, China. 3 Department of Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 4 Department of Thyroid Breast Surgery, The Affiliated Yixing Hospital, of Jiangsu University, Wuxi, Jiangsu, China.)

出处: Animal models and experimental medicine 2026

关键词: animal models;pharmaceutical development;solid tumors.

摘要: Background: In preclinical research, tumor growth inhibition in subcutaneous models is frequently employed to evaluate therapeutic efficacy; however, ...

作者: Qihang Yao #  1, Guangwen Chen #  2, Yang Yu #  1, Zeping Chen  1, Xiao An  3, Xueqian Xie  4, Qingguo Wang  4, Desheng Chen  5, Hongcheng Sun  6 (Affiliations 1 Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 85 Wujin Road, Hongkou, Shanghai, 200080, China. 2 Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. 3 Department of Neoplasms and Interventional Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. 4 Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. 5 Department of Hepatic Surgery and Liver Transplantation Center, The Third Affiliated Hospital of Sun Yat-Sen University, 600 Tianhe Road, Tianhe, Guangzhou, 510630, China. cdsdoctor@163.com. 6 Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 85 Wujin Road, Hongkou, Shanghai, 200080, China. hongcheng.sun@shgh.cn.)

出处: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2026

关键词: Anti-tumor immune response;Conversion therapy;Tislelizumab;Transarterial chemoembolization;Unresectable hepatocellular carcinoma.

摘要: Purpose: We analyzed the clinical efficacy and safety of conversion therapy for unresectable hepatocellular carcinoma (uHCC) using transarterial chemo ...

作者: Xiaoyu Jin 1, Jiahui Wang 1, Runyi Cao 1, Dongsheng Jiang 1 2 3 (Affiliations 1 Precision Research Center For Refractory Diseases Shanghai General Hospital Shanghai Jiao Tong University School of Medicine Shanghai China. 2 Trauma Center Shanghai General Hospital Shanghai Jiao Tong University School of Medicine Shanghai China. 3 State Key Laboratory of Innovative Immunotherapy School of Pharmacy Shanghai Jiao Tong University Pioneer Research Institute For Molecular and Cell Therapies Shanghai Jiao Tong University Shanghai China.)

出处: MedComm 2026

关键词: Wnt signaling;fibrosis;myofibroblast activation;secreted frizzled‐related protein (SFRP);therapeutic targeting.

摘要: The Wnt signaling pathway deeply participates in multiple physiological and pathological processes. Its activity is intricately regulated by a diverse ...

作者: Lei Zhu1,2;Lin Zhu1,2;Youzhuang Zhu1;Junwei Zhang1;Junwei Fang3;Lei Zhang1CA1;Dongyue Chai1CA21Department of Anesthesiology, Shandong Provincial Key Medical and Health Laboratory of Anesthesia and Brain Function, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, China;2These authors contributed equally to this work.;3National Clinical Research Center for Eye Diseases, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China)

出处: Clinical Nutrition ESPEN 2026

关键词: anesthesia;emergence delirium;isopentenyl pyrophosphate;kidney transplant;metabolomics.

摘要: Background and Aims Emergence delirium (ED) is common after general anesthesia, but preoperative metabolic risk factors are not well defined. This stu ...

作者: Qinyi Zhang  1, Sihui Yu  2, Hao Wu  1, Jiawen Zhang  1   3 (Affiliations 1 Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 Department of Gynecologic Oncology, Zhongshan Hospital, Fudan University, Shanghai, China. 3 Reproductive Medicine Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.)

出处: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2026

关键词: FinnGen;Mendelian randomization;anticoagulant therapy;aspirin;heparin;miscarriage;thrombohemostasis.

摘要: Objective: The causal relevance of thrombohemostatic factors and anticoagulant drug targets to miscarriage remains unclear. This study aims to systema ...

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