作者： Licheng Sun  ¹, Ruonan Wang  ¹, Guangyi Hu  ¹, Huazhen Liu  ¹, Kangjia Lv  ¹, Yi Duan  ¹, Ning Shen  ¹, Jiali Wu  ¹, Jing Hu  ¹, Yujuan Liu  ¹, Qihuang Jin  ², Fang Zhang  ³, Xun Xu  ⁴ （Affiliations 1 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, 200080, Shanghai, China; National Clinical Research Center for Eye Diseases, 200080, Shanghai, China; Shanghai Key Laboratory of Fundus Diseases, 200080, Shanghai, China; Shanghai Engineering Center for Visual Science and Photomedicine, 200080, Shanghai, China; Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, 200080, Shanghai, China. 2 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, 200080, Shanghai, China; National Clinical Research Center for Eye Diseases, 200080, Shanghai, China; Shanghai Key Laboratory of Fundus Diseases, 200080, Shanghai, China; Shanghai Engineering Center for Visual Science and Photomedicine, 200080, Shanghai, China; Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, 200080, Shanghai, China. Electronic address: qihuang.jin@shgh.cn. 3 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, 200080, Shanghai, China; National Clinical Research Center for Eye Diseases, 200080, Shanghai, China; Shanghai Key Laboratory of Fundus Diseases, 200080, Shanghai, China; Shanghai Engineering Center for Visual Science and Photomedicine, 200080, Shanghai, China; Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, 200080, Shanghai, China. Electronic address: zhangfang2018@sjtu.edu.cn. 4 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, 200080, Shanghai, China; National Clinical Research Center for Eye Diseases, 200080, Shanghai, China; Shanghai Key Laboratory of Fundus Diseases, 200080, Shanghai, China; Shanghai Engineering Center for Visual Science and Photomedicine, 200080, Shanghai, China; Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, 200080, Shanghai, China. Electronic address: drxuxun@sjtu.edu.cn.）

出处： Experimental eye research 2021 P108718

关键词： Diabetic retinopathy;Inflammation;Retina;Single cell RNA sequencing.

摘要： Diabetic retinopathy (DR) is an irreversible and progressive diabetic complication leading to visual impairment, even blindness. Due to the delicate a ...

作者： Xiaoxiao Meng  ¹ , Kan Liu  ² , Hui Xie  ¹ , Yong Zhu  ¹ , Wei Jin  ¹ , Jian Lu  ¹ , Ruilan Wang  ¹ （Affiliations 1 Department of Critical Care Medicine, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 201620, P.R. China. 2 Department of Diving Medicine, Faculty of Nautical Medicine, Second Military Medical University, Shanghai 200082, P.R. China.）

出处： Molecular medicine reports 2021 Vol.24 No.1 P525

关键词： endoplasmic reticulum stress;epithelial‑mesenchymal transition;paraquat;pulmonary fibrosis.

摘要： Pulmonary fibrosis is the primary reason for mortality in patients with paraquat (PQ) poisoning. Our previous study demonstrated that epithelial‑mesen ...

作者： Rui Tang  ¹ , Weidong Wu, Huiyong Jiang, Yizhong Zhang, Nan Liu, Nina Wei （Affiliation 1 Department of Hernia and Abdominal Wall Surgery, East Hospital Affiliated to Tongji University Department of Gastrointestinal Surgery, Shanghai General Hospital, Shanghai Department of General Surgery, Northeast International Hospital, Shenyang, Liaoning Province Department of Gastrointestinal Surgery, The Affiliated Hospital of Medical School of Ningbo University, Ningbo, Zhejiang Province, China.）

出处： Surgical laparoscopy, endoscopy & percutaneous techniques 2021

摘要： Objectives: Endoscopic totally extraperitoneal sublay (TES) repair seems to be a promising procedure for treating ventral hernias because repairing at ...

作者： Masood Ur Rehman Kayani  ¹ , Wanqiu Huang  ² , Ru Feng  ¹ , Lei Chen  ¹ （Affiliations 1 Center for Microbiota and Immunological Diseases, Shanghai General Hospital, Shanghai Institute of Immunology, Shanghai Jiao Tong University, School of Medicine, Shanghai 2,000,025, China. 2 Shanghai Institute of Immunology, Shanghai Jiao Tong University, School of Medicine, Shanghai 200,000, China.）

出处： Briefings in bioinformatics 2021 Pbbab030

关键词： MAG annotation;MAG refinement;MAG taxonomic classification;de novo assembly;genome binning;metagenome assembly validation;metagenome-assembled genomes;read preprocessing.

摘要： Recent advances in high-throughput sequencing technologies and computational methods have added a new dimension to metagenomic data analysis i.e. geno ...

作者： Weidong Wu  ^{1   2} , Zhihua Han  ³ , Bin Hu  ¹ , Chun Du  ¹ , Zehua Xing  ¹ , Chao Zhang  ² , Jianqing Gao  ² , Bin Shan  ¹ , Chun Chen  ² （Affiliations 1 State Key Laboratory of Material Processing and Die and Mould Technology and School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan, China. 2 Department of Orthopaedic Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China. 3 Trauma Center, Department of Orthopaedics and Traumatology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China.）

出处： Annals of translational medicine 2021 Vol.9 No.2 P169

关键词： Three-dimensional reconstruction (3D reconstruction);cervical spine;finite element;methodology.

摘要： Three-dimensional (3D) reconstruction and finite element analysis (FEA) have been extensively used to simulate cervical biomechanics. However, instruc ...

作者： Jie Liu  ^{1   2} , Li Li  ² , Ning Luo  ² , Qi Liu  ² , Li Liu  ² , Dandan Chen  ² , Zhongping Cheng  ^{2   3} , Xiaowei Xi  ¹ （Affiliations 1 Department of Obstetrics and Gynecology, Shanghai General Hospital of Nanjing Medical University, Shanghai 200080, P.R. China. 2 Department of Obstetrics and Gynecology, Shanghai Tenth People\'s Hospital, Clinical College of Nanjing Medical University, Shanghai 200072, P.R. China. 3 Gynecologic Minimally Invasive Surgery Research Center, Tongji University School of Medicine, Shanghai 200072, P.R. China.）

出处： Experimental and therapeutic medicine 2021 Vol.21 No.2 P163

关键词： CA125;IL-6;IL-8;LPS;TNF-α.

摘要： Cancer antigen 125 (CA125), encoded by the mucin 16 cell surface associated (MUC16) gene, has been widely used as a biomarker for ovarian cancer (OC) ...

作者： Ya Li  ¹, Chong Wang  ², Yang Gao  ³, Liang Zhou  ⁴ （Affiliations 1 Department of Clinical Medicine, Dalian Medical University, Dalian 116044, China. 2 Department of Obstetrics and Gynecology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. 3 Department of Pathology and Pathophysiology, Hubei Provincial Key Laboratory of Developmentally Originated Disease, School of Basic Medical Sciences, Wuhan University, Wuhan 430071, China. 4 Department of Urology, Central South University, Changsha 410013, China.）

出处： Journal of oncology 2021 Vol.2021 P3632576

摘要： Background: Kidney renal clear cell carcinoma (KIRC) is the most prevalent renal malignancy. The therapeutic strategies for advanced KIRC are very few ...

作者： Guiling Ding  ^{1   2}, Meng Guo  ³, Yelin Yang  ², Chen Sun  ², Shengyong Wu  ⁴, Xingchen Liu  ², Jin Wang  ², Hui Jiang  ², Yanfang Liu  ², Jianming Zheng  ² （Affiliations 1 Department of Pathology, Shanghai General Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China. 2 Department of Pathology, Changhai Hospital Affiliated to Navy Medical University (Second Military Medical University), Shanghai, China. 3 National Key Laboratory of Medical Immunology & Institute of Immunology, Naval Medical University (Second Military Medical University), Shanghai, China. 4 Department of Health Statistics, Naval Medical University (Second Military Medical University), Shanghai, China.）

出处： Frontiers in oncology 2021 Vol.11 P694933

关键词： immune cell;large histological sections;nomogram;pancreatic ductal adenocarcinoma;prognosis;tumor microenvironment.

摘要： Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant tumor and is insensitive to radiotherapy and chemotherapy, as it is highly correlated wi ...

作者： Ting-Ting Wu  ¹ , Te Liu  ² , Xuan Li  ¹ , Ya-Jing Chen  ¹ , Tian-Jiao Chen  ¹ , Xiao-Ying Zhu  ¹ , Jiu-Lin Chen  ² , Qing Li  ³ , Ye Liu  ¹ , Ya Feng  ¹ , Yun-Cheng Wu  ¹ （Affiliations 1 Department of Neurology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, P.R. China. 2 Shanghai Geriatric Institute of Chinese Medicine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200031, P.R. China. 3 The State Key Laboratory of Medical Neurobiology, The Institutes of Brain Science and the Collaborative Innovation Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai, 200032, P.R. China.）

出处： Human molecular genetics 2021 Vol.30 No.12 Pddab069

摘要： In the originally published version of this article, the Western blot bands of p16 and p14 in Figure 4d were inadvertently misplaced and a corrected i ...

作者： Xuan Lin  ^{1   2   3   4}, Longyun Ye  ^{1   2   3   4}, Xu Wang  ^{1   2   3   4}, Zhenyu Liao  ^{1   2   3   4}, Jia Dong  ^{1   2   3   4}, Ying Yang  ^{1   2   3   4}, Rulin Zhang  ⁵, Hao Li  ^{1   2   3   4}, Pengcheng Li  ^{1   2   3   4}, Lei Ding  ^{1   2   3   4}, Tianjiao Li  ^{1   2   3   4}, Wuhu Zhang  ^{1   2   3   4}, Shuaishuai Xu  ^{1   2   3   4}, Xuan Han  ^{1   2   3   4}, Huaxiang Xu  ^{1   2   3   4}, Wenquan Wang  ^{1   2   3   4}, Heli Gao  ^{1   2   3   4}, Xianjun Yu  ^{1   2   3   4}, Liang Liu  ^{1   2   3   4} （Affiliations 1 Department of Pancreatic Surgery, Shanghai Cancer Center, Fudan University, Shanghai 200032, China. 2 Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China. 3 Shanghai Pancreatic Cancer Institute, Shanghai 200032, China. 4 Pancreatic Cancer Institute, Fudan University, Shanghai 200032, China. 5 Department of Laboratory Medicine, Shanghai General Hospital, Shanghai 200080, China.）

出处： Cancers 2021 Vol.13 No.15 P3678

关键词： follicular helper T cells;immune microenvironment;immunosuppression;neoadjuvant chemotherapy;pancreatic ductal adenocarcinoma.

摘要： Immunosuppression is an important factor for the poor prognosis of pancreatic ductal adenocarcinoma (PDAC). Follicular helper T cells (Tfh cells) play ...