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作者: Xiaoqing Lu #  1   2, Liwei An #  3, Guangjian Fan #  1   4, Lijuan Zang #  5, Weiyi Huang  1, Junjian Li  1, Jun Liu  1, Weiyu Ge  1, Yuwei Huang  6, Jingxuan Xu  1, Shaoqian Du  1, Yuan Cao  1, Tianhao Zhou  1, Huijing Yin  1, Li Yu  6, Shi Jiao  7, Hongxia Wang  8 (Affiliations 1 State Key Laboratory of Oncogenes and Related Genes, Department of Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 Department of Breast Surgery, Shanxi Cancer Hospital, Chinese Academy of Medical Sciences, Taiyuan, Shanxi, China. 3 Department of Medical Ultrasound, Shanghai Tenth People\'s Hospital, Tongji University Cancer Center, School of Medicine, Tongji University, Shanghai, China. 4 Precision Research Center for Refractory Diseases, Institute for Clinical Research, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 5 Department of Pathology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 6 State Key Laboratory of Membrane Biology, Tsinghua-Peking University Joint Center for Life Sciences, School of Life Science, Tsinghua University, Beijing, China. 7 State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China. 8 State Key Laboratory of Oncogenes and Related Genes, Department of Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. whx365@126.com.)

出处: Cell research 2022

摘要: TSPAN family of proteins are generally considered to assemble as multimeric complexes on the plasma membrane. Our previous work uncovered that TSPAN8 ...

作者: Ying Shen  1, Junxian Li  2, Hairong Tian  3, Ye Ji  3, Ziyun Li  3, Junxi Lu  4, Huijuan Lu  4, Bo Liu  3, Fang Liu  2   4 (Affiliations 1 Department of Endocrinology & Metabolism, The Affiliated Jiangsu Shengze Hospital of Nanjing Medical University, Suzhou, China. 2 Department of Endocrinology & Metabolism, Shanghai Jiao-Tong University School of Medicine Affiliated Shanghai General Hospital, Shanghai, China. 3 Department of Endocrinology and Metabolism, Jin Shan Branch of Shanghai Sixth People\'s Hospital, Shanghai, China. 4 Department of Endocrinology & Metabolism, Shanghai Key Laboratory of Diabetes, Shanghai Clinical Medical Center of Diabetes, Shanghai Key Clinical Center of Metabolic Diseases, Shanghai Institute for Diabetes, Shanghai Jiao-Tong University Affiliated Sixth People\'s Hospital, Shanghai, China.)

出处: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2022 Vol.38 No.2 P158-163

关键词: Complement factor Ba;first prenatal test of gestation;gestational diabetes mellitus;perinatal outcome;propensity score-matched.

摘要: Objective: This study was to assess the alteration of circulating complement factor Ba (CFBa) within 11 to 17 weeks of gestation and its association w ...

作者: Wei Chen  1, Chuan Huang  1   2, Peng Li  1, Feng Liu  1, Jian Sun  1, Zi-Jue Zhu  1, Jing Zhai  1, Yuan Xu  1, Yan Hong  1, Jian-Lin Hu  1, Yun-Peng Peng  3, Zhen-Bo Zhang  1, Yu Wu  1, Zheng Li  1 (Affiliations 1 Department of ART, Department of Andrology, Center for Men\'s Health, Institute of Urologic Medical Center, Shanghai General Hospital, Shanghai Key Lab of Reproductive Medicine, Shanghai Jiao Tong University, Shanghai 200080, China. 2 Clinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha 410000, China. 3 Department of Urology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China.)

出处: Asian journal of andrology 2022

关键词: Cryopiece system;intracytoplasmic sperm injection outcome;rare sperm cryopreservation.

摘要: Cryopreservation of rare testicular-retrieved spermatozoa for intracytoplasmic sperm injection (ICSI) in patients with severe oligozoospermia and azoo ...

作者: Xueqiang Wang  1, Weiqiang Lv  1, Jie Xu  1, Adi Zheng  1, Mengqi Zeng  1, Ke Cao  1, Xun Wang  1, Yuting Cui  1, Hao Li  1, Meng Yang  1, Yongping Shao  2, Fang Zhang  3   4, Xuan Zou  5   6, Jiangang Long  1, Zhihui Feng  2   5   7, Jiankang Liu  1   7 (Affiliations 1 Center for Mitochondrial Biology and Medicine, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi\'an Jiaotong University, Xi\'an, Shaanxi, 710049, China. 2 Frontier Institute of Science and Technology, Xi\'an Jiaotong University, Xi\'an, Shaanxi, 710049, China. 3 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Xi\'an, Shanghai, 200240, China. 4 National Clinical Research Center for Eye Diseases, Shanghai, 200240, China. 5 National & Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital of Xi\'an Jiaotong University, Xi\'an, Shannxi, 710004, China. 6 Shaanxi Provincial Clinical Research Center for Hepatic & Splenic Diseases, The Second Affiliated Hospital of Xi\'an Jiaotong University, Xi\'an, Shannxi, 710004, China. 7 University of Health and Rehabilitation Sciences, Qingdao, Shandong, 266071, China.)

出处: Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Pe2105587

关键词: SDHAF4;complex II;dietary restriction;insulin sensitivity;mitochondria.

摘要: Alternate day fasting (ADF), the most popular form of caloric restriction, has shown to improve metabolic health in preclinical subjects, while intrin ...

作者: Zhuo Wang  1, Yuyang Zhao  2, Xiaohan Shen  1, Yichun Zhao  1, Ziyuan Zhang  1, Huming Yin  3, Xiaojun Zhao  3, Haitao Liu  2, Qihui Shi  1   4   5 (Affiliations 1 Key Laboratory of Whole-Period Monitoring and Precise Intervention of Digestive Cancer (SMHC), Minhang Hospital and Shanghai Key Laboratory of Medical Epigenetics, Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China. 2 Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. 3 Department of Urology, The First Affiliated Hospital of Soochow University, Suzhou 215006, China. 4 Institute of Fudan-Minhang Academic Health System, Minhang Hospital, Fudan University, Shanghai 201199, China. 5 International Co-Laboratory of Medical Epigenetics and Metabolism (Ministry of Science and Technology), Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.)

出处: Analytical chemistry 2022 Vol.94 No.5 P2607-2614

摘要: As one of the prime applications of liquid biopsy, the detection of tumor-derived whole cells and molecular markers is enabled in a noninvasive means ...

作者: Liming Zhang  1, Kun Wang  2, Yuheng Huang  3, Hui Zhang  4, Long Zhou  3, Ang Li  5, Yunyan Sun  6 (Affiliations 1 Department of Obstetrics and Gynecology, Women\'s Hospital School of Medicine Zhejiang University, Hangzhou, Zhejiang province, 310000, PR China. 2 Shanghai East Hospital of Tongji University, Shanghai, 200120, PR China. 3 Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, PR China. 4 Department of Obstetrics and Gynecology, Shanghai General Hospital, Nanjing Medical University, Shanghai, 200080, PR China. 5 School of Life Science and Technology, Tongji University, Shanghai, 200092, PR China. Electronic address: liang@tongji.edu.cn. 6 Department of Obstetrics and Gynecology, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, 200092, PR China. Electronic address: sunyunyan8606@xinhuamed.com.cn.)

出处: Biomaterials 2022 Vol.282 P121411

关键词: Cervical cancer;Dendritic cells;Indocyanine green;Nanoparticles;Therapeutic HPV vaccine.

摘要: There is a lack of effective treatment methods for advanced cervical, and the therapeutic HPV vaccine is a promising option. The design of an efficien ...

作者: Feng Wang  1, Shuguang Wang  2, Liping Nan  3, Jiawei Lu  1, Ziqi Zhu  1, Jintao Yang  4, Dong Zhang  5, Junjian Liu  3, Xiao Zhao  6, Desheng Wu  1 (Affiliations 1 Department of Spine Surgery, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China. 2 Department of Orthopedic, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China. 3 Department of Orthopedic, Shanghai Tenth People\'s Hospital, School of Medicine, Tongji University, Shanghai, China. 4 College of Materials Science and Engineering, Zhejiang University of Technology, Hangzhou, China. 5 Department of Chemical, Biomolecular, and Corrosion Engineering, College of Engineering and Polymer Science, The University of Akron, Akron, OH, United States. 6 Department of Anesthesiology, Shanghai General Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China.)

出处: Frontiers in bioengineering and biotechnology 2022 Vol.10 P833887

关键词: adhesive hydrogel;antibacterial hydrogel;conductive hydrogel;wound dressing;wound healing.

摘要: Any sort of wound injury leads to the destruction of skin integrity and wound formation, causing millions of deaths every year and accounting for 10% ...

作者: Zhen Guo MD;Lin Sun MD;Bailing Li MD;Rui Tian MD;Xiaolin Zhang MD;Zhongwei Zhang MD;Sean P. Clifford MD;Yuan Liu BS;Jiapeng Huang MD, PhD;Xin Li MD (7 Department of Statistics Center, Shanghai Chest Hospital, Shanghai JiaoTong University, Shanghai China 8 Department of Cardiovascular Surgery. Zhongshan Hospital, Fudan University, Shanghai China 5 Department of Intensive Care Unit, Fudan University Shanghai Cancer Center, Shanghai China 6 Department of Anesthesiology & Perioperative Medicine, University of Louisville, Louisville, KY, USA 3 Department of Emergency and Critical Care, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai China 4 Department of Intensive Care Unit, Shanghai Public Health Clinical Center, Fudan University, Shanghai China 1 Department of Cardiovascular Surgery. Shanghai Chest Hospital, Shanghai JiaoTong University, Shanghai China 2 Department of Cardiovascular Surgery, Shanghai Changhai Hospital, The Second Military Medical University, Shanghai China)

出处: Journal of Cardiothoracic and Vascular Anesthesia 2021

关键词: COVID-19;Coronavirus;SARS-CoV-2;extracorporeal membrane oxygenation;anticoagulation;thrombosis;ECMO

摘要: Objective To explore special coagulation characteristics and anticoagulation management in extracorporeal membrane oxygenation assisted patients with ...

作者: Song, Chenlong1;Zhou, Chongzhi1 (1 Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China)

出处: Journal of Experimental & Clinical Cancer Research 2021 Vol.40 P1-16

关键词: EMT;Gastric cancer;HOXA10;METTL3;Smad2/3;TGFB2

摘要: Background: Homeobox A10 (HOXA10) belongs to the HOX gene family, which plays an essential role in embryonic development and tumor progression. We pre ...

作者: Wang, Rujia1;Wang, Qian1 (1 Department of Pediatrics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China)

出处: Journal of Oncology 2021 P1-10

摘要: Background. Neuroblastoma is a common solid tumor originating from the sympathetic nervous system, commonly found in children, and it is one of the le ...

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