作者： Zhi-qiang Ye¹;Xu-bin Dong²;Han-bin Chen³;Dian-na Gu³CA1;Zheng-jun Qiu⁴CA2 （1 a Department of General surgery, Shanghai General Hospital of Nanjing Medical University, Shanghai, People’s Republic of China;b Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People’s Republic of China; 2 b Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People’s Republic of China; 3 c Department of Medical Oncology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People’s Republic of China; 4 a Department of General surgery, Shanghai General Hospital of Nanjing Medical University, Shanghai, People’s Republic of China）

出处： All Life 2021 Vol.14 No.1 P569-576

关键词： Circular RNA CDR1as;microRNA-7;autophagy;breast cancer stem cell;competitive endogenous RNA

摘要： Competitive endogenous RNA (ceRNA) plays a vital role in cancer stem cells. In the present study, we aimed to investigate the role of the circular RNA ...

作者： Jun Jie Fan ^{#  1   2} , Qi Xiang Mei ^{#  1   2} , Guo Ying Deng ^{#  3} , Ze Hua Huang  ¹ , Yang Fu  ¹ , Jun Hui Hu  ¹ , Chun Lan Huang  ² , Ying Ying Lu  ² , Lun Gen Lu  ² , Xing Peng Wang  ² , Yue Zeng  ² （Affiliations 1 Shanghai Key Laboratory of Pancreatic Disease, Shanghai JiaoTong University School of Medicine, Shanghai, China. 2 Department of Gastroenterology, Shanghai General Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China. 3 Trauma Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Journal of digestive diseases 2021 Vol.22 No.6 P363-372

关键词： Acute pancreatitis;Multi-organ failure;Se@SiO2 nanocomposites;nrf2;oxidative stress.

摘要： Objective: Acute pancreatitis (AP) is a common digestive tract disease caused by gall stone obstruction, alcoholism and other factors. Pancreatitis ma ...

作者： Wu, Tingting;Liu, Te;Li, Xuan;Chen, Yajing;Chen, Tianjiao;Zhu, Xiaoying;Chen, Jiulin;Li, Qing;Liu, Ye;Feng, Ya;Wu, Yuncheng （Department of Neurology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China; Shanghai Geriatric Institute of Chinese Medicine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200031, China; State Key Laboratory of Medical Neurobiology, Institutes of Brain Science and the Collaborative Innovation Center for Brain Science, Shanghai Medical College, Shanghai, 200032, China）

出处： Human Molecular Genetics 2021 Vol.30 No.12 P1172

摘要： In the originally published version of this article, the Western blot bands of p16 and p14 in Figure 4d were inadvertently misplaced and a corrected i ...

作者： Wang P.^1,2;Hu X.^1,3;Zhu C.⁴;Liu M.⁴;Yuan Y.^5,2;Ke B.^1,5 （1 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; 2 Shanghai Key Laboratory of Fundus Disease, Shanghai, China; 3 Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China; 4 Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China; 5 National Clinical Research Center for Eye Diseases, Shanghai, China）

出处： Ophthalmic Research 2021 Vol.64 No.1 P128-138

关键词： Myopia;Microvascular density;Optical coherence tomography angiography;Femtosecond laser-assisted laser in situ keratomileusis

摘要： Purpose: The purpose of this study was to determine the retinal microvasculature in myopic patients after refractive surgery. Methods: Thirty-six righ ...

作者： Yang Yan^1,2;Lei Zhou^3,2;Zhengwang Sun⁴CA1;Dianwen Song³CA2;Yiyun Cheng¹CA3 （1 Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241, China; 2 These authors contributed equally on this manuscript.; 3 Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China; 4 Department of Musculoskeletal Oncology, Fudan University Shanghai Cancer Center, Shanghai, 200032, China）

出处： Bioactive Materials 2021

关键词： Boronated polymer;Dendrimers;Intracellular protein delivery;Bone targeting;Cancer therapy

摘要： The treatment of malignant bone tumors by chemotherapeutics often receives poor therapeutic response due to the specific physiological bone environmen ...

作者： Weihong Guo  ¹ , Xiaoxing Zhang  ² , Longshuai Lin  ¹ , Hongjie Wang  ¹ , Enjun He  ¹ , Gangyang Wang  ¹ , Qinghua Zhao  ¹ （Affiliations 1 Department of Orthopaedics, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200080, China. 2 Department of Orthopedic Surgery, Chongqing University Central Hospital, Chongqing, 400000, China.）

出处： Journal of biochemistry 2021 Pmvab045

关键词： ROS/JNK signaling pathway;apoptosis;autophagy;disulfiram/copper;osteosarcoma.

摘要： Given the huge cost, long research and development (R&D) time and uncertain side effects of discovering new drugs, drug repositioning of those approve ...

作者： Kebin Cheng  ^{1   2} , Weining Xiong  ³ , Xin Zhou  ⁴ , Huiping Li  ² , Junhua Zheng  ⁵ , Jinfu Xu  ² （Affiliations 1 Medical College of Soochow University, Suzhou, China. 2 Department of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China. 3 Department of Respiratory Medicine, Ninth People\'s Hospital, Shanghai Jiaotong University, Shanghai, China. 4 Department of Respiratory and Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, China. 5 Department of Urology, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, China.）

出处： Annals of translational medicine 2021 Vol.9 No.2 P163

关键词： 2019 novel coronavirus disease (COVID-19);clinical characteristics;lymphocyte;prognosis;treatment.

摘要： Background: While the 2019 novel coronavirus disease (COVID-19) outbreak has been largely kept under control in China, it remains a global pandemic, a ...

作者： Yaping Zhang  ¹, Beibei Jiang  ², Lu Zhang  ², Marcel J W Greuter  ³, Geertruida H de Bock  ⁴, Hao Zhang  ¹, Xueqian Xie  ¹ （Affiliations 1 Department of Radiology, Shanghai General Hospital of Nanjing Medical University, Haining Rd.100, Shanghai 200080. China. 2 Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Haining Rd.100, Shanghai 200080. 0. 3 Department of Radiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713GZ Gro-ningen. Netherlands. 4 Department of Epidemiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713GZ Groningen. Netherlands.）

出处： Current medical imaging 2021

关键词： Artificial intelligence;computed tomography;detectability;lung nodule;radiologist observation;real-world study.

摘要： Background: Artificial intelligence (AI)-based automatic lung nodule detection system improves the detection rate of nodules. It is important to evalu ...

作者： Jingyang Feng  ^{1   2   3   4}, Xiaotong Yang  ^{1   2}, Mengqiao Xu  ¹, Yuwei Wang  ¹, Xiang Shi  ⁵, Yumeng Zhang  ¹, Peirong Huang  ^{1   2   3   4} （Affiliations 1 Department of Ophthalmology, Shanghai General Hospital (Shanghai First People\'s Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 National Clinical Research Center for Eye Diseases, Shanghai, China. 3 Shanghai Key Laboratory of Fundus Disease, Shanghai, China. 4 Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China. 5 Department of Ophthalmology, Affiliated Hospital of Nantong University, Nantong, China.）

出处： Frontiers in medicine 2021 Vol.8 P655013

关键词： OCT angiography;epiretinal membrane;microperimetry;prognostic factors;vessel density.

摘要： Purpose: To investigate the correlation between retinal capillary structure and macular function in patients with idiopathic epiretinal membrane (iERM ...

作者： Mengsha Sun  ¹, Qiyu Bo  ², Bing Lu  ², Xiaodong Sun  ^{2   3   4}, Minwen Zhou  ^{2   3   4} （Affiliations 1 Department of Ophthalmology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China. 2 Department of Ophthalmology, Shanghai General Hospital, Shanghai First People\'s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 3 National Clinical Research Center for Eye Diseases, Shanghai, China. 4 Shanghai Key Laboratory of Fundus Diseases, Shanghai, China.）

出处： Frontiers in medicine 2021 Vol.8 P778117

关键词： China;adults;association;sleep duration;vision impairment.

摘要： Objective: This study aims to investigate the association of sleep duration with vision impairment (VI) in middle-aged and elderly adults. Methods: Th ...