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作者: Sicong Li  1   2, Ruiwei Zhao  3, Haidong Zou  1   2   4   5   6 (Affiliations 1 Department of Ophthalmology, Shanghai General Hospital (Shanghai First People\'s Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. 2 Shanghai Eye Diseases Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai 200040, China. 3 Fudan University, Shanghai, China. 4 Shanghai Key Laboratory of Fundus Diseases, Shanghai 200080, China. 5 National Clinical Research Center for Eye Diseases, Shanghai 200080, China. 6 Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai 200080, China.)

出处: Chinese medical journal 2021 Vol.135 No.3 P253-260

摘要: Diabetic retinopathy (DR) is an important cause of blindness globally, and its prevalence is increasing. Early detection and intervention can help cha ...

作者: Shiyue Qin  1   2, Chaoyang Zhang  3   4, Haifeng Qin  1   5, Hai Xie  6   7, Dawei Luo  3   4, Qinghua Qiu  3   4   8, Kun Liu  3   4, Jingting Zhang  3   4, Guoxu Xu  1, Jingfa Zhang  3   4 (Affiliations 1 Department of Ophthalmology, the Second Affiliated Hospital of Soochow University, Suzhou, China. 2 Department of Ophthalmology, Taizhou People\'s Hospital, Taizhou, China. 3 Department of Ophthalmology, Shanghai General Hospital (Shanghai First People\'s Hospital), Shanghai Jiao Tong University, Shanghai, China. 4 National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China. 5 Department of Ophthalmology, Changhai Hospital, Shanghai, China. 6 Department of Regenerative Medicine, Tongji Eye Institute, Tongji University School of Medicine, Shanghai, China. 7 Department of Pharmacology, Tongji Eye Institute, Tongji University School of Medicine, Shanghai, China. 8 Department of Ophthalmology, Shigatse People\'s Hospital, Xizang, China.)

出处: Frontiers in physiology 2021 Vol.12 P791442

关键词: OCT angiography;anti-VEGF;cystoid edema;diabetic macular edema;hyperreflective foci;inflammation;subretinal fluid.

摘要: Purpose: The aim was to investigate the effect and underlying mechanism of anti-vascular endothelial growth factor (anti-VEGF) in diabetic macular ede ...

作者: Gaoda Ju;Tianhao Zhou;Rui Zhang;Xiaozao Pan;Bing Xue;Sen Miao (Department of Medical Oncology, Beijing Cancer Hospital, Peking University, Beijing, China Shanghai First People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China Department of Pathology, Affiliated Hospital of Jining Medical University, Jining, China Department of Pathology, Affiliated Hospital of Jining Medical University, Jining, China Department of Pathology, Affiliated Hospital of Jining Medical University, Jining, China Department of Pathology, Affiliated Hospital of Jining Medical University, Jining, China)

出处: PeerJ 2021 Vol.9 Pe11929

关键词: Hepatocellular carcinoma;DUSP12;Mutation;Tumorigenesis;Prognosis

摘要: Background Dual specificity protein phosphatase (DUSP)12 is an atypical member of the protein tyrosine phosphatase family, which are overexpressed in ...

作者: Xiaolu Yang  1, Xuemei Zhang  1, Suqin Yu  1 (Affiliation 1 Department of Ophthalmology, Shanghai General Hospital, Shanghai, China.)

出处: JAMA ophthalmology 2021

作者: Ye-Ye Zhang  1   2, Hui Zhao  3, Jin-Yan Lin  4, Shi-Nan Wu  5, Xi-Wang Liu  4   6, Hong-Dan Zhang  4   6, Yi Shao  5, Wei-Feng Yang  2   4   6 (Affiliations 1 Department of Electronic Engineering, School of Science, Hainan University, Haikou, China. 2 Department of Electronic Engineering, College of Engineering, Shantou University, Shantou, China. 3 Department of Ophthalmology, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, National Clinical Research Center for Eye Diseases, Shanghai, China. 4 Research Center for Advanced Optics and Photoelectronics, Department of Physics, College of Science, Shantou University, Shantou, China. 5 Jiangxi Centre of National Ophthalmology Clinical Research Center, Department of Ophthalmology, The First Affiliated Hospital of Nanchang University, Nanchang, China. 6 Department of Mathematics, College of Science, Shantou University, Shantou, China.)

出处: Frontiers in medicine 2021 Vol.8 P774344

关键词: DenseNet CNN;convolution neural network;deep learning;in-vivo confocal microscopy;meibomian gland dysfunction.

摘要: Background: In recent years, deep learning has been widely used in a variety of ophthalmic diseases. As a common ophthalmic disease, meibomian gland d ...

作者: Yuan Zhang  1, Peng-Shan Zhang  1, Ze-Yin Rong  1, Chen Huang  1 (Affiliation 1 Department of Gastrointestinal Surgery, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, P. R. China.)

出处: Gastroenterology report 2021 Vol.9 No.6 P489-504

关键词: epidemiology;gastric cancer;pathology;prognosis;therapeutics.

摘要: Gastric cancer (GC) is one of the most common malignant tumors of the digestive tract, posing a significant risk to human health. Over the past 10 yea ...

作者: Chen, Jing1;Li, Chun-xiao1;Shao, Si-hui1;Yao, Ming-hua1;Su, Yi-jin1;Wu, Rong1 (1 Department of Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China)

出处: Clinical Hemorheology & Microcirculation 2021 P1-10

关键词: contrast-enhanced ultrasound;logistic model;metastasis;Small breast cancer

摘要: To investigate the association between ultrasound appearances and pathological features in small breast cancer.A total of 186 small breast cancers in ...

作者: Xiao-Jian Zhou  1, Zhen Qin, Jiao Lu, Jian-Guo Hong (Affiliation 1 Department of Paediatrics, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai 200080, China.)

出处: Chinese medical journal 2021 Vol.134 No.24 P2954-2961

摘要: Background: Despite the recommendation of inhaled corticosteroids (ICSs) plus long-acting beta 2-agonist (LABA) and leukotriene receptor antagonist (L ...

作者: Yan Li  1, Lungen Lu  1, Xiaobo Cai  1 (Affiliation 1 Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.)

出处: Biomolecules 2021 Vol.11 No.12 P1907

关键词: cell transplantation;end-stage liver disease;liver progenitor cells;liver regeneration;massive hepatic necrosis.

摘要: Liver transplantation is the only curative option for end-stage liver disease; however, the limitations of liver transplantation require further resea ...

作者: Pusen Wang  1, Lin Zhong  1 (Affiliation 1 Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.)

出处: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2021 Vol.27 No.12 P1867

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