作者： Wu, Yueming¹;Lin, Yaofa^2,3;Cong, Zihao⁴;Chen, Kang⁴;Xiao, Ximian⁴;Wu, Xue⁴;Liu, Longqiang⁴;She, Yunrui⁴;Liu, Shiqi⁴;Zhou, Ruiyi⁴;Yin, Gang^2,3;Shao, Xiaoyan⁵;Dai, Yidong⁵;Lin, Haodong^2,3;Liu, Runhui^1,4 （1 State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology 2 Department of Orthopedic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 3 Jiading Branch of Shanghai General Hospital 4 Key Laboratory for Ultrafine Materials of Ministry of Education, Frontiers Science Center for Materiobiology and Dynamic Chemistry, Research Center for Biomedical Materials of Ministry of Education, East China University of Science and Technology 5 Shanghai Ruijin Rehabilitation Hospital）

出处： Advanced Functional Materials 2021 P1

关键词： antibacterial;chronic osteomyelitis;host defense peptides;MRSA;peptide polymers

摘要： Chronic osteomyelitis is a painful and serious disease normally caused by infected surgical prostheses or infected fractures. Currently, antibiotic‐lo ...

作者： Rongjia Su  ¹, Yuan Liu  ², Xiaomei Wu  ¹, Jiangdong Xiang  ¹, Xiaowei Xi  ¹ （Affiliations 1 Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. 2 Reproductive Medicine Center, Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.）

出处： Frontiers in molecular biosciences 2021 Vol.8 P762741

关键词： BRCA;PARP inhibitors;WGCNA;homologous recombination deficiency;ovarian cancer;overall survival.

摘要： Background: The homologous recombination (HR) pathway defects in cancers induced abrogation of cell cycle checkpoints, resulting in the accumulation o ...

作者： Ying, Chenting¹;Guo, Chenyang¹;Wang, Zhenlin²;Chen, Yiming¹;Sun, Jiahui¹;Qi, Xin¹;Chen, Yisheng³;Tao, Jie¹ （1 Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China 2 Department of Neurosurgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China 3 Department of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, China）

出处： BioMed Research International 2021 P1-10

摘要： Background. The main aim of this study was to develop a nomogram prediction model for poor functional prognosis after patellar fracture surgery in the ...

作者： Xiao Zhao  ¹, Shi-Tong Li  ², Lian-Hua Chen  ¹, Kun Liu  ¹, Ming Lian  ¹, Hui-Juan Wang  ¹, Yi-Jiao Fang  ³ （Affiliations 1 Anesthesiology Department, Shanghai General Hospital of Nanjing Medical University, Shanghai 200000, China. 2 Anesthesiology Department, Shanghai General Hospital of Nanjing Medical University, Shanghai 200000, China. lishitongs021@163.com. 3 Department of Anesthesiology, Fudan University Shanghai Cancer Center, Shanghai 200032, China.）

出处： World journal of clinical cases 2021 Vol.9 No.35 P10861-10870

关键词： Anesthesia, General;Gastroesophageal reflux;Intraoperative period;Retrospective studies;Risk factors;Surgery.

摘要： Background: Gastroesophageal reflux (GER) affects up to 20% of the adult population and is defined as troublesome and frequent symptoms of heartburn o ...

作者： Ni, Jian Bo^1,2;Zhu, Mei Ying³;Li, Kai^1,2;Dai, Wei Ming¹;Lu, Lun Gen¹;Wan, Xin Jian³;Wan, Rong^1,2;Cai, Xiao Bo¹ （1 Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China 2 Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China 3 Department of Gastroenterology, Shanghai Sixth Peopleʼs Hospital, Shanghai Jiao Tong University, Shanghai, China）

出处： Journal of Digestive Diseases 2021 Vol.22 No.12 P721-726

关键词： cap‐assisted;colonoscopy;endoscopic retrograde cholangiopancreatography;gastrectomy;Roux‐en‐Y reconstruction

摘要： Objectives: Endoscopic retrograde cholangiopancreatography (ERCP) in patients with Roux‐en‐Y reconstruction after total gastrectomy is difficult to be ...

作者： Zhongyi Jiang  ¹, Changchang Xing  ², Pusen Wang  ¹, Xueni Liu  ¹, Lin Zhong  ¹ （Affiliations 1 Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 Department of Cardiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Frontiers in cell and developmental biology 2021 Vol.9 P748269

关键词： bioinformatics analysis;biomarker;chemokine;liver hepatocellular carcinoma;tumor microenvironment.

摘要： Background: Liver hepatocellular carcinoma (LIHC) is the third leading cause of cancer-related death and the sixth most common solid tumor worldwide. ...

作者： Mei Kang  ¹, Hui Zhang  ², Jia Zhang  ³, Kaifeng Huang  ⁴, Jinyan Zhao  ⁴, Jie Hu  ⁵, Cong Lu  ², Jiashen Shao  ², Jianrong Weng  ², Yuemin Yang  ², Yan Zhuang  ², Xianming Xu  ² （Affiliations 1 Clinical Research Center, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. 2 Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. 3 Department of Obstetrics and Gynecology, Suining County People\'s Hospital, Xuzhou, China. 4 Department of Clinical Laboratory, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. 5 Nuclear Medicine Department, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.）

出处： Frontiers in endocrinology 2021 Vol.12 P779210

关键词： B lymphocytes;IgA;gestational diabetes mellitus;nomogram;risk factors.

摘要： Objective: Gestational diabetes mellitus (GDM) is a serious threat to maternal and child health. However, there isn\'t a standard predictive model for ...

作者： Yixin Xu  ^{1   2   3}, Junjie Hu  ⁴, Can Cao  ², Mili Zhang  ², Youdong Liu  ², Haonan Chen  ¹, ShanShan Wei  ², Ziyan Zhu  ², Yuqin Yang  ⁵, Liang Yu  ^{1   2}, Jikun Li  ^{1   2} （Affiliations 1 Department of General Surgery, Shanghai General Hospital of Nanjing Medical University, Shanghai, China. 2 Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 3 Department of General Surgery, Wujin Hospital Affiliated with Jiangsu University, The Wujin Clinical College of Xuzhou Medical University, Changzhou, Jiangsu, China. 4 Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 5 Department of Laboratory Animal Centre, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Journal of oncology 2021 Vol.2021 P2427427

摘要： Despite dramatic responses to immune checkpoint inhibitors (ICIs) in patients with colon cancer (CC) harboring deficient mismatch repair (dMMR), more ...

作者： Xing Li  ¹, Cailiang Wu  ¹, Xuexin Zhou  ¹, Jin Zhang  ¹, Huifang Lu  ¹, Shuying Chen  ¹, Xianming Xu  ¹, Hao Wu  ¹ （Affiliation 1 Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine Shanghai 200080, China.）

出处： American journal of translational research 2021 Vol.13 No.11 P12973-12979

关键词： New concept of labor;maternal and neonatal outcomes;painless delivery.

摘要： Objective: To explore the possible influence of painless delivery on the maternal and neonatal outcomes under the guidance of new concept of labor. Me ...

作者： Da-Hong Chen  ¹, Ji-Gang Zhang  ², Chuan-Xing Wu  ³, Qin Li  ¹ （Affiliations 1 Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 Clinical Research Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 3 Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Frontiers in cell and developmental biology 2021 Vol.9 P778582

关键词： cancer therapy;epigenetics;m6A RNA modification;non-coding RNA;tumorigenesis mechanism.

摘要： Recently, N6-methyl-adenosine (m6A) ribonucleic acid (RNA) modification, a critical and common internal RNA modification in higher eukaryotes, has gen ...