上海交通大学附属第一人民医院肿瘤科是上海市三甲综合医院中最早设立的肿瘤专科，是医院“十二五”期间重点发展的学科之一。2009年，医院整合肿瘤相关学科资源，成立了肿瘤中心，学科带头人黄倩教授，中心主任王理伟教授，肿瘤中心副主任王红霞（兼肿瘤科副主任[主持，南]）、刘勇副主任医师，北部执行主任李琦主任医... [详细]
作者： Zhengyan Chang, Runzhi Huang, Wanting Fu, Jiehan Li, Guo Ji, Jinglei Huang, Weijun Shi, Huabin Yin, Weifeng Wang, Tong Meng, Zongqiang Huang, Qing Wei, Huanlong Qin （Affiliations 1 Department of Pathology, Shanghai Tenth People\'s Hospital, Tongji University School of Medicine, Shanghai, China. 2 Department of Orthopaedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China. 3 Division of Spine, Department of Orthopedics, Tongji Hospital Affiliated to Tongji University School of Medicine, Shanghai, China. 4 Tongji University School of Medicine, Tongji University, Shanghai, China. 5 Department of Orthopedics, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. 6 Department of Central Laboratory, Shanghai Tenth People\'s Hospital, Shanghai, China. 7 Tongji University Cancer Center, Shanghai Tenth People\'s Hospital of Tongji University, School of Medicine, Tongji University, Shanghai, China. 8 Department of Gastrointestinal Surgery, Shanghai Tenth People\'s Hospital, Tongji University School of Medicine, Shanghai, China.）
出处： Frontiers in cell and developmental biology 2020 Vol.8 P688
关键词： colon adenocarcinoma;competing endogenous RNA network;metastasis;prognosis;tumor-infiltrating immune cell.
摘要： Background: Colon adenocarcinoma (COAD) is a malignant and lethal tumor in digestive system and distance metastasis lead to poor prognosis. The metast ...
作者： Jian-Hua Zhou, Zhi-Xian Yao, Zhong Zheng, Jun Yang, Rui Wang, Shi-Jie Fu, Xu-Feng Pan, Zhi-Hong Liu, Ke Wu （Affiliations 1 Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, People\'s Republic of China. 2 Department of Urology, Shanghai General Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, People\'s Republic of China.）
出处： OncoTargets and therapy 2020 Vol.13 P9701-9719
关键词： G-MDSCs;ITM2B;exosomes;lung cancer;miRNA-143-3p;proliferation.
摘要： Background: The immune environment of lung cancer is complex, and the critical immune factors that promote lung cancer progression need to be explored ...
作者： JianQiao Zhou;LiXue Yin;Xi Wei;Sheng Zhang;YanYan Song;BaoMing Luo;JianChu Li;LinXue Qian;LiGang Cui;Wen Chen;ChaoYang Wen;YuLan Peng;Qin Chen;Man Lu;Min Chen;Rong Wu;Wei Zhou;EnSheng Xue;YingJia Li;LiChun Yang;ChengRong Mi;RuiFang Zhang;Gang Wu;GuoQing Du;DaoZhong Huang;WeiWei Zhan （Affiliations 1 Department of Ultrasound, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200025, China. zhousu30@126.com. 2 Institute of Ultrasound in Medicine, The Affiliated Sichuan Provincial People\'s Hospital of Electronic Science and Technology University of China, Chengdu, 610071, China. yinlixue@yahoo.com. 3 Department of Diagnostic and Therapeutic Ultrasound, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, 300060, China. 4 Department of Biostatistics, Institute of Medical Sciences, Shanghai Jiaotong University School of Medicine, Shanghai, 200025, China. 5 Department of Ultrasound, SunYat-sen Memorial Hospital, SunYat-sen University, Guangzhou, 510120, China. 6 Department of Ultrasound, Peking Union Medical College Hospital, Beijing, 100730, China. 7 Department of Ultrasound, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China. 8 Department of Ultrasound, Peking University Third Hospital, Beijing, 100191, China. 9 Department of Ultrasound, Peking University International Hospital, Beijing, 102206, China. 10 Department of Ultrasound, West China Hospital of Sichuan University, Chengdu, 610041, China. 11 Department of Ultrasound, The Affiliated Sichuan Provincial People\'s Hospital of Electronic Science and Technology University of China, Chengdu, 610071, China. 12 Department of Ultrasound, Sichuan Cancer Hospital, Chengdu, 610041, China. 13 Department of Ultrasound, Fudan University Shanghai Cancer Center, Shanghai, 200032, China. 14 Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China. 15 Department of Ultrasound, Shanghai First People\'s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, 201620, China. 16 Department of Ultrasound, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200025, China. 17 Department of Ultrasound, Fujian Medical University Union Hospital, Fuzhou, 350001, China. 18 Department of Ultrasound, Nanfang Hospital of Southern Medical University, Guangzhou, 510515, China. 19 Department of Ultrasound, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Kunming, 650031, China. 20 Department of Ultrasound, General Hospital of Ningxia Medical University, Yinchuan, 750021, China. 21 Department of Ultrasound, The First Affiliated Hospital, Zhengzhou University, Zhengzhou, 450052, China. 22 Department of Ultrasound, Henan Provincial People\'s Hospital, Zhengzhou, 450003, China. 23 Department of Ultrasound, The Second Affiliated Hospital of Harbin Medical University, Harbin, 150086, China. 24 Department of Ultrasound, Tongji Hospital, Tongji Medical Colloge, Huazhong University of Science and Technology, Wuhan, 430030, China. 25 Department of Ultrasound, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200025, China. shanghairuijinus@163.com.）
出处： Endocrine 2020 Vol.70 No.2 P256-279
关键词： Thyroid nodule;Diagnostic imaging;Ultrasonography;Risk assessment;Biopsy;Fine needle
摘要： Thyroid nodules are very common all over the world, and China is no exception. Ultrasound plays an important role in determining the risk stratificati ...
作者： Yu Wang;Rong Yang;Minghui Zhao;Wenyu Guo;Lun Zhang;Wenchao Zhang;Xudong Wang （Department of Maxillofacial and Otorhinolaryngology Oncology, Tianjin Medical University Cancer Institute and Hospital, Key Laboratory of Cancer Prevention and Therapy, Tianjin Cancer Institute, National Clinical Research Center of Cancer Department of Maxillofacial and Otorhinolaryngology Oncology, Tianjin Medical University Cancer Institute and Hospital, Key Laboratory of Cancer Prevention and Therapy, Tianjin Cancer Institute, National Clinical Research Center of Cancer Molecular Diagnostic Laboratory of Cancer Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine Department of Maxillofacial and Otorhinolaryngology Oncology, Tianjin Medical University Cancer Institute and Hospital, Key Laboratory of Cancer Prevention and Therapy, Tianjin Cancer Institute, National Clinical Research Center of Cancer Department of Maxillofacial and Otorhinolaryngology Oncology, Tianjin Medical University Cancer Institute and Hospital, Key Laboratory of Cancer Prevention and Therapy, Tianjin Cancer Institute, National Clinical Research Center of Cancer Department of Maxillofacial and Otorhinolaryngology Oncology, Tianjin Medical University Cancer Institute and Hospital, Key Laboratory of Cancer Prevention and Therapy, Tianjin Cancer Institute, National Clinical Research Center of Cancer Department of Maxillofacial and Otorhinolaryngology Oncology, Tianjin Medical University Cancer Institute and Hospital, Key Laboratory of Cancer Prevention and Therapy, Tianjin Cancer Institute, National Clinical Research Center of Cancer）
出处： World Journal of Surgical Oncology 2020 Vol.18 No.1 P1-8
关键词： Maxillary sinus squamous cell carcinoma;Surgery;Comprehensive treatment;Neoadjuvant chemoradiotherapy;Adjuvant chemotherapy;Adjuvant radiotherapy
摘要： Background Maxillary sinus squamous cell carcinoma (MSSCC) is a relatively rare head and neck cancer with poorly defined prognosis, and the present st ...
作者： Tong, Yingying;Guo, Dong;Yan, Dong;Ma, Chunmin;Shao, Fei;Wang, Yugang;Luo, Shudi;Lin, Liming;Tao, Jingjing;Jiang, Yuhui;Lu, Zhimin;Xing, Dongming （1 The Institute of Cell Metabolism and Diseases, Shanghai Key Laboratory of Pancreatic Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China 2 Cancer Center, Beijing Luhe Hospital, Capital Medical University, Beijing, 101149, China 3 Zhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, and Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310029, China 4 Cancer Institute, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, 266071, China 5 Qingdao Cancer Institute, Qingdao, Shandong, 266071, China 6 State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China 7 Department of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China 8 School of Life Sciences, Tsinghua University, Beijing, 100084, China）
出处： Cancer Letters 2020 Vol.469 P1-10
关键词： β-catenin;14-3-3ζ;Cell proliferation;Glycolysis;Invasion;KAT2A;Pancreatic cancer;Succinylation;Succinyltransferase
摘要： Frequently occurring histone lysine succinylation is a newly identified histone modification that can be regulated by KAT2A histone succinyltransferas ...
作者： Xiao Feng, Lina Zhang, Shanbao Ke, Tao Liu, Liuwei Hao, Pan Zhao, Wenzhi Tu, Shundong Cang （Affiliations 1 Department of Oncology, Henan Provincial People\'s Hospital, People\'s Hospital of Zhengzhou University, People\'s Hospital of Henan University, Zhengzhou, Henan 450003, P.R. China. 2 Henan Provincial Key Laboratory of Kidney Disease and Immunology, Henan Provincial People\'s Hospital, People\'s Hospital of Zhengzhou University, People\'s Hospital of Henan University, Zhengzhou, Henan 450003, P.R. China. 3 Department of Radiotherapy, Henan Provincial People\'s Hospital, People\'s Hospital of Zhengzhou University, People\'s Hospital of Henan University, Zhengzhou, Henan 450003, P.R. China. 4 Department of Physical Examination and Health Management, Henan Provincial People\'s Hospital, People\'s Hospital of Zhengzhou University, People\'s Hospital of Henan University, Zhengzhou, Henan 450003, P.R. China. 5 Department of Neurology, Henan Provincial People\'s Hospital, People\'s Hospital of Zhengzhou University, People\'s Hospital of Henan University, Zhengzhou, Henan 450003, P.R. China. 6 Cancer Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, P.R. China.）
出处： Oncology letters 2020 Vol.20 No.3 P2356-2368
关键词： bioinformatics analysis;glioma;glycoprotein non-metastatic melanoma protein B;prognosis;tissue microarray.
摘要： Glycoprotein non-metastatic melanoma protein B (GPNMB), a transmembrane glycoprotein, has been reported to be involved in tumor progression, but its p ...
作者： Huiyan,Luo ;Qi,Zhao ;Wei,Wei ;Lianghong,Zheng ;Shaohua,Yi ;Gen,Li ;Wenqiu,Wang ;Hui,Sheng ;Hengying,Pu ;Haiyu,Mo ;Zhixiang,Zuo ;Zexian,Liu ;Chaofeng,Li ;Chuanbo,Xie ;Zhaolei,Zeng ;Weimin,Li ;Xiaoke,Hao ;Yuying,Liu ;Sumei,Cao ;Wanli,Liu ;Sarah,Gibson ;Kang,Zhang ;Guoliang,Xu ;Rui-Hua,Xu （Sun Yat-sen University Cancer Center \'(1)\' ; State Key Laboratory of Oncology in South China [2] ; Collaborative Innovation Center for Cancer Medicine [3] ; Guangzhou 510060 [4] ; P. R. China. [5] ; Guangzhou Youze Biological Pharmaceutical Technology Company Ltd. [6] ; Guangzhou 510005 [7] ; P.R. China. [8] ; Huazhong University of Science and Technology Tongji Medical College [9] ; Wuhan 430030 [10] ; Guangzhou Women and Children\'s Medical Center [11] ; Guangzhou 510623 [12] ; Shanghai General Hospital [13] ; Shanghai 200080 [14] ; Molecular Medicine Center [15] ; West China Hospital [16] ; Sichuan University [17] ; Chengdu 610041 [18] ; Department of Clinical Laboratory Medicine [19] ; Xijing Hospital [20] ; Fourth Military Medical University [21] ; Xi\'an 710032 [22] ; Faculty of Medicine [23] ; Macau University of Science and Technology [24] ; Macau 999078 [25] ; P. R. China. xurh@sysucc.org.cn. [26]）
出处： Science translational medicine 2020 Vol.12 No.524
摘要： Circulating tumor DNA (ctDNA) has emerged as a useful diagnostic and prognostic biomarker in many cancers. Here, we conducted a study to investigate t ...
作者： Lin Shen;Qi Li;Wei Wang;Lingjun Zhu;Qingchuan Zhao;Yongzhan Nie;Bo Zhu;Dong Ma;Xiaoyan Lin;Xiaohong Cai;Weijia Fang;Cike Peng;Yun Chen;Honghao Fang;Zheng Yin;Hongyan Li;Ning Wang;Ruihua Xu （Department of Clinical Oncology, Beijing Cancer Hospital, Beijing, China; Department of Oncology, Shanghai General Hospital, Shanghai, China; Department of Oncology, The First People’s Hospital of Foshan, Foshan, Guangdong, China; Department of Oncology, Jiangsu Province Hospital, Nanjing, China; Xijing Hospital, Fourth Military Medical University, Xi’an, China; Xijing Hospital, Fourth Military Medical University, Xi’an, China; Institute of Cancer, Xinqiao Hospital, Third Military Medical University, Chongqing, China; Department of Oncology, Guangdong General Hospital, Guangzhou, Guangdong, China; Department of Medical Oncology, Fujian Medical University Union Hospital, Xiamen, Fujian, China; Department of Medical Oncology, Sichuan Cancer Hospital and Institute, Chengdu, Sichuan, China; School of Medicine, The First Hospital of Zhejiang Province, Hangzhou, Zhejiang, China; Health Economics and Outcomes Research, Eli Lilly and Company China Affiliate, Shanghai, China; Health Economics and Outcomes Research, Eli Lilly and Company China Affiliate, Shanghai, China; Real World Insights, IQVIA, Shanghai, China; Real World Insights, IQVIA, Beijing, China; Health Economics and Outcomes Research, Eli Lilly and Company China Affiliate, Shanghai, China; Health Economics and Outcomes Research, Eli Lilly and Company China Affiliate, Shanghai, China; Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China）
出处： Journal of Medical Economics 2020 Vol.23 No.5 P456-463
关键词： Real-world evidence;colorectal cancer;metastatic colorectal cancer;EMR;direct medical costs;China
摘要： Objectives: To describe direct medical costs associated with each line of treatment among metastatic colorectal cancer (mCRC) patients in China. Me ...
作者： Bo Jing, Tong Wang, Beibei Sun, Jianhua Xu, Dongliang Xu, Yueling Liao, Hongyong Song, Wenzheng Guo, Kaimi Li, Min Hu, Siwei Zhang, Jing Ling, Yanbin Kuang, Tuo Zhang, Binhua P Zhou, Feng Yao, Jiong Deng （Affiliations 1 Key Laboratory of Cell Differentiation and Apoptosis of Chinese Minister of Education, Shanghai Jiao Tong University, Shanghai, China. 2 Shanghai Key Laboratory for Tumor Microenvironment and Inflammation, Shanghai Jiao Tong University, Shanghai, China. 3 Translational Medical Research Center, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China. 4 Department of Pathology, Kunming Medical University, Kunming, Yunnan, China. 5 Department of Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 6 Department of Respiratory Medicine, The Second Affiliated Hospital, Dalian Medical University, Dalian, China. 7 Department of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China. 8 Department of Molecular and Cellular Biochemistry, Markey Cancer Center, University of Kentucky College of Medicine, Lexington, Kentucky. 9 Department of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China. jiongdeng@shsmu.edu.cn feng.yao@shchest.org. 10 Key Laboratory of Cell Differentiation and Apoptosis of Chinese Minister of Education, Shanghai Jiao Tong University, Shanghai, China. jiongdeng@shsmu.edu.cn feng.yao@shchest.org.）
出处： Cancer research 2020 Vol.80 No.4 P784-797
摘要： Cancer cells that succeed in forming metastasis need to be reprogrammed to evade immune surveillance and survive in a new microenvironment. This is fa ...
作者： Shao-Feng Lin, Yu-Zhen Zheng, Xiao-Qiang Li, Hai-Peng Xu, Jun-Jie Wang, Wei Wang, Qing-Yuan Huang, Da Wu, Chen-Xi Zhong, Shen-Shen Fu, Lian-Xiong Yuan, Si-Chao Wang, Rui-Xing Luo, Wen-Yu Zhai, Ben-Tong Yu, Kun-Shou Zhu （Affiliations 1 Department of Thoracic Surgery, Fujian Cancer Hospital & Fujian Medical University Cancer Hospital& Fujian Provincial Key Laboratory of Tumor Biotherapy, Fuzhou, China. 2 Department of Thoracic Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. 3 Department of Thoracic Surgery, Peking University Shenzhen Hospital, Shenzhen, China. 4 Department of Thoracic Oncology, Fujian Cancer Hospital & Fujian Medical University Cancer Hospital, Fuzhou, China. 5 Department of Surgery, Cleveland Clinic, Cleveland, Ohio, USA. 6 S. Arthur Localio Laboratory, Department of Surgery, New York University School of Medicine, New York, NY, USA. 7 Department of Thoracic Surgery, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, Shanghai, China. 8 Department of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China. 9 Department of Ultrasonography, Guangzhou First People\'s Hospital, Guangzhou Medical University, Guangzhou, China. 10 Office of Research Service, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangzhou, China. 11 Department of Thoracic Surgery, Guangdong Provincial People\'s Hospital, Guangzhou, China. 12 Department of Thoracic Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation, Guangzhou, China. 13 Department of Thoracic Surgery, First Affiliated Hospital of Nanchang University, Nanchang, China.）
出处： Annals of translational medicine 2020 Vol.8 No.20 P1292
关键词： SEER;Small-cell lung cancer (SCLC);early-stage lung cancer;treatment.
摘要： Background: The optimal treatment modality for patients with stage IA (T1N0M0) small-cell lung cancer (SCLC) is still unclear. Methods: Patients who r ...
