上海交通大学附属第一人民医院肿瘤科是上海市三甲综合医院中最早设立的肿瘤专科，是医院“十二五”期间重点发展的学科之一。2009年，医院整合肿瘤相关学科资源，成立了肿瘤中心，学科带头人黄倩教授，中心主任王理伟教授，肿瘤中心副主任王红霞（兼肿瘤科副主任[主持，南]）、刘勇副主任医师，北部执行主任李琦主任医... [详细]
作者： Wang, Z.;Xue, X.;Lu, H.;He, Y.;Lu, Z.;Chen, Z.;Yuan, Y.;Tang, N.;Dreyer, C.A.;Quigley, L.;Curro, N.;Lam, K.S.;Walton, J.H.;Lin, T.-Y.;Louie, A.Y.;Gilbert, D.A.;Liu, K.;Ferrara, K.W.;Li, Y. （a Department of Radiology, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China; b Department of Biochemistry and Molecular Medicine, UC Davis Comprehensive Cancer Center, University of California Davis, Sacramento, CA, United States; c Department of Radiology, First Affiliated Hospital of Soochow University, Suzhou, China; d Department of Physics, University of California, Davis, CA, United States; e Department of Physics, Georgetown University, Washington, DC, United States; f Department of Materials Science and Engineering, University of Tennessee, Knoxville, TS, United States; g Division of Hematology/Oncology, Department of Internal Medicine, University of California Davis, Sacramento, CA, United States; h UC Davis NMR Facility, Davis, CA, United States; i Department of Biomedical Engineering, University of California Davis, Davis, CA, United States; j Department of Radiology, Stanford University, Palo Alto, CA, United States）
出处： Nature Nanotechnology 2020 Vol.15 No.6 P482-490
摘要： Distance-dependent magnetic resonance tuning (MRET) technology enables the sensing and quantitative imaging of biological targets in vivo, with the ad ...
作者： Xu, S.;Moss, T.J.;Laura Rubin, M.;Ning, J.;Eterovic, K.;Yu, H.;Jia, R.;Fan, X.;Tetzlaff, M.T.;Esmaeli, B. （a Orbital Oncology & Ophthalmic Plastic Surgery, Department of Plastic Surgery, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 1488, Houston, TX 77030, United States; b Department of Ophthalmology, Ninth People’s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; c Department of Bioinformatics, The University of Texas MD Anderson Cancer Center, Houston, TX, United States; d Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, United States; e Institute for Personalized Cancer Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX, United States; f Pathology Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; g Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States; h Department of Translational and Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States）
出处： Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2020 Vol.33 No.7 P1256-1263
摘要： Ocular adnexal sebaceous carcinoma (OASeC) is an aggressive eyelid carcinoma. Analysis of molecular-genetic drivers of this disease could reveal new p ...
作者： Libin Song, Zhixiao Fang, Chuanfang Pan, Xiangyuan Chen, Xiang Qian, Yunyun Cai, Xiumei Zhang, Luming Liu （Affiliations 1 Department of Integrative Oncology, Fudan University, Shanghai Cancer Center, Shanghai, China. 2 Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. 3 Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 4 Department of Oncology, Longhua Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China. 5 Department of Geriatrics, Huadong Hospital, Shanghai Medical College, Fudan University, Shanghai, China. 6 Institute of Cancer and Basic Medicine (ICBM), Chinese Academy of Sciences, Zheijang, China. 7 Department of Traditional Chinese Medicine, Zhejiang Cancer Hospitall, Zheijang, China. 8 Department of Integrated Traditional Western Medicine, Minhang Branch of Fudan University of Shanghai Cancer Center, Shanghai, China.）
出处： Frontiers in oncology 2020 Vol.10 P584330
关键词： Babao Dan;enrichment analysis;metabolism;pancreatic cancer;transcriptome.
摘要： Background and aims: Pancreatic ductal adenocarcinoma (PDAC) is one of refractory malignancies without efficient therapeutics. Babao Dan (BBD) was par ...
作者： Xinjian Liu, Xuhui Bao, Mengjie Hu, Hanman Chang, Meng Jiao, Jin Cheng, Liyi Xie, Qian Huang, Fang Li, Chuan-Yuan Li （Affiliations 1 Department of Dermatology, Duke University Medical Center, Durham, NC, USA. 2 Department of Biochemistry, Molecular Cancer Research Center, School of Medicine, Sun Yat-sen University, Shenzhen, Guangdong, China. 3 Molecular Diagnostic Laboratory of Cancer Center, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. 4 Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China. 5 Department of Dermatology, Duke University Medical Center, Durham, NC, USA. Chuan.Li@duke.edu. 6 Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, USA. Chuan.Li@duke.edu. 7 Duke Cancer Institute, Duke University Medical Center, Durham, NC, USA. Chuan.Li@duke.edu.）
出处： Nature 2020
摘要： Despite its success in achieving the long-term survival of 10-30% of treated individuals, immune therapy is still ineffective for most patients with c ...
作者： Xing-Wen Fan MD;Yu Yang MD;Hong-Bing Wang MD;Yin Xu MD;Mei Kang MD;Li-Yi Xie MD, PhD;Ling Li MD, PhD;Wen-Tao Fang MD, PhD;Kuai-Le Zhao MD, PhD;Hai-Quan Chen MD, PhD;Jia-Qing Xiang MD;Yee C. Ung MD;C. Shun Wong MD;Guo-Liang Jiang MD, PhD;Kai-Liang Wu MD, PhD （2 Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China 1 Department of Radiation Oncology, Shanghai Cancer Center, Fudan University, Shanghai 200032, China 4 Department of Thoracic Surgery, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University 200030, China 3 Clinical Research Center, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University 200080, Shanghai, China 6 Department of Radiation Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto ON M4N3M5, Canada 5 Department of Thoracic Surgery, Shanghai Cancer Center, Fudan University, Shanghai 200032, China 7 Department of Radiation Oncology, Shanghai Engineering Research Center of Proton and Heavy Ion Radiation Therapy, Shanghai Proton and Heavy Ion Center, Shanghai 201315, Chin）
出处： International Journal of Radiation Oncology*Biology*Physics 2020
关键词： thymoma;thymic carcinoma;intensity-modulated radiotherapy;etoposide/cisplatin
摘要： Introduction This prospective phase II study evaluated the efficacy and safety of intensity-modulated radiotherapy (IMRT) plus etoposide/cisplatin (E ...
作者： Wen, Shihong (AUTHOR);Li, Xiang (AUTHOR);Ling, Yihong (AUTHOR);Chen, Shaoqian (AUTHOR);Deng, Qiwen (AUTHOR);Yang, Lu (AUTHOR);Li, Ying (AUTHOR);Shen, Jiantong (AUTHOR);Qiu, Yuxin (AUTHOR);Zhan, Yaqing (AUTHOR);Lai, Hanjin (AUTHOR);Zhang, Xuyu (AUTHOR);Ke, Zunfu (AUTHOR)( kezunfu@mail.sysu.edu.cn);Huang, Wenqi (AUTHOR)( scorpiosslove@aliyun.com) （1 Department of Anesthesiology, The First Affiliated Hospital, Sun Yat‐sen University, Guangzhou, China 2 Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China 3 State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat‐sen University Cancer Center, Guangzhou, China 4 Department of Pathology, Sun Yat‐sen University Cancer Center, Guangzhou, China 5 Department of Medical Laboratory, The First Affiliated Hospital, Sun Yat‐sen University, Guangzhou, China 6 State Key Laboratory of Applied Microbiology Southern China, Guangzhou, China 7 Guangdong Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou, China 8 Surgical Intensive Care Unit, The First Affiliated Hospital, Sun Yat‐sen University, Guangzhou, China 9 Department of Pathology, The First Affiliated Hospital, Sun Yat‐sen University, Guangzhou, China）
出处： FASEB Journal 2020 Vol.34 No.3 P4384-4402
关键词： cell death;gut‐liver axis;high‐mobility group box‐1;inflammation
摘要： Reperfusion of the ischemic intestine often leads to drive distant organ injury, especially injuries associated with hepatocellular dysfunction. The p ...
作者： Qingying Wang, Qinyi Zhang, Qingxian Li, Jing Zhang, Jiawen Zhang （Affiliations 1 Department of Obstetrics and Gynecology, Shanghai Tenth People\'s Hospital, School of Medicine, Tongji University, Shanghai, China. 2 Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China. 3 Department of Gynecology and Obstetrics, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China. 4 Department of Integrated Therapy, Shanghai Cancer Center, Fudan University, Shanghai, China. 5 Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.）
出处： Molecular genetics & genomic medicine 2020 Pe1547
关键词： immune infiltration;m6A regulators;ovarian cancer;survival.
摘要： Background: N 6 -methyladenosine (m 6 A) modification is one of the critical gene regulatory mechanisms implicated in cancer biology. However, the r ...
作者： Xiao Gao, Qingwei Wang, Ying Wang, Jiang Liu, Shuang Liu, Jian Liu, Xingli Zhou, Li Zhou, Hui Chen, Linian Pan, Jiwei Chen, Da Wang, Qing Zhang, Shihui Shen, Yu Xiao, Zhipeng Wu, Yiyun Cheng, Geng Chen, Syeda Kubra, Jun Qin, Lan Huang, Pei Zhang, Chuangui Wang, Robb E Moses, David M Lonard, Bert W O\' Malley, Fuad Fares, Bianhong Zhang, Xiaotao Li, Lei Li, Jianru Xiao （Affiliations 1 East China Normal University and Shanghai Changzheng Hospital Joint Research Center for Orthopedic Oncology, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China. 2 Department of Orthopedic Oncology, Changzheng Hospital, The Second Military Medical University, 415 Fengyang Road, Shanghai, 200003, China. 3 Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China. 4 Department of Surgery, Department of Physiology & Cell Biology, College of Medicine, Davis Heart and Lung Research Institute, Wexner Medical Center, The Ohio State University, Columbus, OH, 43210, USA. 5 The Institute of Aging Research, School of Medicine, Hangzhou Normal University, Hangzhou, 310036, Zhejiang, China. 6 Department of Hematology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, China. 7 Reproductive & Developmental Biology Laboratory, National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 27709, USA. 8 The Joint Laboratory of Translational Medicine, National Center for Protein Sciences (Beijing) and Peking University Cancer Hospital, State Key Laboratory of Proteomics, Institute of Lifeomics, 102206, Beijing, China. 9 Department of Physiology and Biophysics, University of California, Irvine, CA, 92697, USA. 10 Department of Pathology, The Second Chengdu Municipal Hospital, Chengdu, 610017, China. 11 Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 12 Department of Molecular and Cellular Biology, Dan L. Duncan Cancer Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA. 13 Department of Human Biology. Faculty of Natural Sciences, University of Haifa, Haifa, 3498838, Israel. 14 Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China. zhkyzhbh.549803@163.com. 15 East China Normal University and Shanghai Changzheng Hospital Joint Research Center for Orthopedic Oncology, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China. xiaotaol@bcm.edu. 16 Department of Molecular and Cellular Biology, Dan L. Duncan Cancer Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA. xiaotaol@bcm.edu. 17 Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China. lllkzj@163.com. 18 East China Normal University and Shanghai Changzheng Hospital Joint Research Center for Orthopedic Oncology, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China. jianruxiao83@163.com. 19 Department of Orthopedic Oncology, Changzheng Hospital, The Second Military Medical University, 415 Fengyang Road, Shanghai, 200003, China. jianruxiao83@163.com.）
出处： Nature communications 2020 Vol.11 No.1 P4888
摘要： An amendment to this paper has been published and can be accessed via a link at the top of the paper.
作者： Jiawen,Zhang ;Qinyi,Zhang ;Cong,Sun ;Yanjuan,Huang ;Jing,Zhang ;Qingying,Wang （Department of Obstetrics and Gynecology \'(1)\' ; Shanghai Tenth People\'s Hospital [2] ; School of Medicine [3] ; Tongji University [4] ; Shanghai [5] ; China. [6] ; Shanghai General Hospital [7] ; Shanghai Jiaotong University [8] ; First Hospital of Zibo [9] ; Shandong [10] ; School of Pharmacy [11] ; Shanghai University of Medicine and Health Sciences [12] ; Department of Integrated Therapy [13] ; Shanghai Cancer Center [14] ; Fudan University [15] ; China; Department of Oncology [16] ; Shanghai Medical College [17] ; China. Electronic address: crystalzhang12@163.com. [18] ; China. Electronic address: wangqingying@tongji.edu.cn. [19]）
出处： Biomedecine & pharmacotherapie 2020 Vol.125 P110000
关键词： ARF/ARL family;ARL4C;Endometrial cancer;Metformin;Prognosis
摘要： Members of ADP-ribosylation factor (ARF)/ARF-like protein (ARL) family regulate malignant phenotype of cancer cells. The present study aims to investi ...
作者： James L,Mulshine ;Ricardo S,Avila ;Ed,Conley ;Anand,Devaraj ;Laurie Fenton,Ambrose ;Tanya,Flanagan ;Claudia I,Henschke ;Fred R,Hirsch ;Robert,Janz ;Ryutaro,Kakinuma ;Stephen,Lam ;Annette,McWilliams ;Peter M A,Van Ooijen ;Matthijs,Oudkerk ;Ugo,Pastorino ;Anthony,Reeves ;Patrick,Rogalla ;Heidi,Schmidt ;Daniel C,Sullivan ;Haije H J,Wind ;Ning,Wu ;Murry,Wynes ;Xie,Xueqian ;David F,Yankelevitz ;John K,Field （Rush University, Chicago, IL. \'(1)\' ; Accumetra, LLC, Clifton Park, NY. [2] ; University of Liverpool, Liverpool, United Kingdom. [3] ; University College, London, United Kingdom. [4] ; GO2 Foundation, Washington, DC. [5] ; Partnership Against Cancer, Toronto, Ontario, Canada. [6] ; Icahn School of Medicine at Mount Sinai, New York, NY. [7] ; Mount Sinai Health System, New York, NY. [8] ; University of Groningen, Groningen, Netherlands. [9] ; National Cancer Center Hospital, Tokyo, Japan. [10] ; University of British Columbia, Vancouver, British Columbia, Canada. [11] ; Fiona Stanley Hospital, Western Australia. [12] ; University Medical College, Groningen, Netherlands. [13] ; Instituti Tumori, Milan, Italy. [14] ; Cornell University, Ithaca, New York, NY. [15] ; Toronto Joint Department of Medical Imaging, University of Toronto, Ontario, Canada. [16] ; Duke University Medical Center, Durham, NC. [17] ; National Cancer Center, Peking Union Medical College, Beijing, China. [18] ; International Association for the Study of Lung Cancer, Denver, CO. [19] ; Shanghai General Hospital, Shanghai, China. [20]）
出处： JCO clinical cancer informatics 2020 Vol.4 P89-99
关键词： JAG1.
摘要： To improve outcomes for lung cancer through low-dose computed tomography (LDCT) early lung cancer detection. The International Association for the Stu ...
