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上海交通大学附属第一人民医院肿瘤科是上海市三甲综合医院中最早设立的肿瘤专科，是医院“十二五”期间重点发展的学科之一。2009年，医院整合肿瘤相关学科资源，成立了肿瘤中心，学科带头人黄倩教授，中心主任王理伟教授，肿瘤中心副主任王红霞（兼肿瘤科副主任[主持，南]）、刘勇副主任医师，北部执行主任李琦主任医... [详细]

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[外文期刊] Toripalimab or placebo plus chemotherapy as first-line treatment in advanced nasopharyngeal carcinoma: a multicenter randomized phase 3 trial

作者： Hai-Qiang Mai^#¹, Qiu-Yan Chen^#¹, Dongping Chen², Chaosu Hu³, Kunyu Yang⁴, Jiyu Wen⁵, Jingao Li⁶, Ying-Rui Shi⁷, Feng Jin⁸, Ruilian Xu⁹, Jianji Pan¹⁰, Shenhong Qu¹¹, Ping Li¹², Chunhong Hu¹³, Yi-Chun Liu¹⁴, Yi Jiang¹⁵, Xia He¹⁶, Hung-Ming Wang¹⁷, Wan-Teck Lim¹⁸, Wangjun Liao¹⁹, Xiaohui He²⁰, Xiaozhong Chen²¹, Zhigang Liu²², Xianglin Yuan²³, Qi Li²⁴, Xiaoyan Lin²⁵, Shanghua Jing²⁶, Yanju Chen²⁷, Yin Lu²⁸, Ching-Yun Hsieh²⁹, Muh-Hwa Yang³⁰, Chia-Jui Yen³¹, Jens Samol^{32 33}, Hui Feng^{34 35}, Sheng Yao^{34 35}, Patricia Keegan³⁵, Rui-Hua Xu³⁶ （Affiliations 1 Department of Nasopharyngeal Carcinoma, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China. 2 Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, China. 3 Fudan University Cancer Center, Shanghai, China. 4 Union Hospital Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. 5 Affiliated Hospital of Guangdong Medical University, Zhanjiang, China. 6 Jiangxi Cancer Hospital, Nanchang, China. 7 Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Changsha, China. 8 Guizhou Cancer Hospital of Guizhou Medical University, Guiyang, China. 9 Shenzhen People's Hospital, Shenzhen, China. 10 Fujian Provincial Cancer Hospital, Fuzhou, China. 11 The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China. 12 West China Hospital of Sichuan University, Chengdu, China. 13 The Second Xiangya Hospital of Central South University, Changsha, China. 14 Taichung Veterans General Hospital, Taichung, Taiwan. 15 Cancer Hospital of Shantou University Medical College, Shantou, China. 16 Jiangsu Cancer Hospital, Nanjing, China. 17 Chang Gung Memorial Hospital, Taoyuan, Taiwan. 18 National Cancer Centre, Singapore City, Singapore. 19 Nanfang Hospital, Guangzhou, China. 20 Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. 21 Zhejiang Cancer Hospital, Hangzhou, China. 22 The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, China. 23 Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. 24 Shanghai General Hospital, Shanghai, China. 25 Fujian Medical University Union Hospital, Fuzhou, China. 26 The Fourth Hospital of Hebei Medical University Hebei Cancer Hospital, Shijiazhuang, China. 27 Hainan General Hospital, Haikou, China. 28 Liuzhou Worker's Hospital, Liuzhou, China. 29 China Medical University Hospital, Taichung, Taiwan. 30 Taipei Veterans General Hospital, Taipei, Taiwan. 31 National Cheng Kung University, Tainan, Taiwan. 32 Tan Tock Seng Hospital, Singapore City, Singapore. 33 Johns Hopkins University, Baltimore, MD, USA. 34 Shanghai Junshi Biosciences, Shanghai, China. 35 TopAlliance Biosciences, Rockville, MD, USA. 36 Department of Medical Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China. xurh@sysucc.org.cn.）

出处： Nature medicine 2021

摘要： Gemcitabine-cisplatin (GP) chemotherapy is the standard first-line systemic treatment for recurrent or metastatic nasopharyngeal carcinoma (RM-NPC). I ...

[外文会议论文] Involved-Field Irradiation in Definitive Chemoradiotherapy for Locoregional Esophageal Squamous Cell Carcinoma: Results From the ESO-Shanghai 1 Trial EI

作者： Zhu, Hongcheng^{1, 2}; Rivin del Campo, Eleonor³; Ye, Jinjun⁴; Simone, Charles B.⁵; Zhu, Zhengfei^{1, 2}; Zhao, Weixin^{1, 2}; Amini, Arya⁶; Zhou, Jialiang⁷; Wu, Chaoyang⁸; Tang, Huarong⁸; Fan, Min^{1, 2}; Li, Ling^{1, 2}; Lin, Qin⁹; Xia, Yi¹⁰; Li, Yunhai¹⁰; Li, Jiancheng¹¹; Mo, Miao^{2, 12}; Jia, Huixun¹³; Lu, Saiquan^{1, 2}; Wang, Juanqi^{1, 2}; Nie, Yongzhan¹⁴; Chen, Junqiang¹¹; Wu, Shixiu¹⁵; Hamaji, Masatsugu¹⁶; Haque, Waqar¹⁷; Jeong, Bae Kwon¹⁸; Shridhar, Ravi¹⁹; Zhang, Zhen^{1, 2}; Chen, Yun^{1, 2}; Zhao, Kuaile^{1, 2}

摘要： Purpose: To evaluate the feasibility and efficacy of involved-field irradiation in definitive chemoradiation therapy for locoregional esophageal squam ...

[外文期刊] Novel theranostic nanoagent based on CuMo2S3-PEG-Gd for MRI-guided photothermal/photodynamic/chemodynamic therapy

作者： Zheng, Nan-Nan¹;Kong, Wen-Yan¹;Huang, Zhi¹;Liu, Xi-Jian¹;Liang, Shan-Hui^{2, 3};Deng, Guo-Ying⁴;Zhao, Lin-Jing¹;Lu, Jie¹ （1 School of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai; 201620, China (2 Department of Oncology, Shanghai Medical College, Fudan University, Shanghai; 200032, China (3 Department of Gynecological Oncology, Fudan University Shanghai Cancer Center, Fudan University, Shanghai; 200032, China (4 Trauma Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai; 201620, China）

出处： Rare Metals 2021

摘要： Cancer is a severe disease, which have troubled human being for a long time. The development of nanotechnology has provided a new way for cancer treat ...

[外文期刊] Irradiation-induced polyploid giant cancer cells are involved in tumor cell repopulation via neosis SCIE SCI

作者： Zhang, Zhengxiang^a;Feng, Xiao^b;Deng, Zheng^a;Cheng, Jin^a;Wang, Yiwei^a;Zhao, Minghui^a;Zhao, Yucui^a;He, Sijia^a;Huang, Qian^a （a Cancer Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; b Department of Oncology, Henan Province People\'s Hospital, Henan University, Zhengzhou, China）

出处： Molecular oncology 2021

关键词： HMGB1;irradiation;neosis;polyploid giant cancer cells;tumor repopulation

摘要： Tumor repopulation occurs when residual tumor cells surviving therapies tenaciously proliferate and re-establish the tumor. The cellular and molecular ...

[外文期刊] Reg4 regulates pancreatic regeneration following pancreatitis via modulating the Notch signaling.

作者： Dai, Juanjuan^1,2,3;He, Yan^1,2;Jiang, Mingjie^2,4;Niu, Mengya^1,2;Li, Bin^1,2;Wu, Zengkai^1,2;Bao, Jingpiao^1,2;Wen, Li^1,2;Wang, Xingpeng^1,2;Hu, Guoyong^1,2 （1 Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 2 Shanghai Key Laboratory of Pancreatic Diseases, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 3 Department of Intensive Care Unit, State Key Laboratory of Oncology in South China, Sun Yat‐sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine 4 Department of Head and Neck, State Key Laboratory of Oncology in South China, Sun Yat‐sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine）

出处： Journal of Cellular Physiology 2021 P1

关键词： ADM;Notch;Reg4;cell proliferation;pancreatic regeneration.

摘要： Pancreatic regeneration after acute pancreatitis is critical in the normal restoration of pancreatic exocrine function, the inhibition of which can ca ...

[外文期刊] Correction to: Tumor-derived exosomal miR-934 induces macrophage M2 polarization to promote liver metastasis of colorectal cancer SCIE SCI

作者： Senlin Zhao;Yushuai Mi;Bingjie Guan;Binbin Zheng;Ping Wei;Yanzi Gu;Zhengxiang Zhang;Sanjun Cai;Ye Xu;Xinxiang Li;Xuefeng He;Xinyang Zhong;Guichao Li;Zhiyu Chen;Dawei Li （Department of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, China Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China Department of Gastrointestinal Surgery, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China Department of General Surgery, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China Cancer Institute, Fudan University Shanghai Cancer Center, Shanghai, China Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China Department of Biobank, Fudan University Shanghai Cancer Center, Shanghai, China Department of Oncology, Yijishan Hospital of Wannan Medical College, Wuhu, China Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China Department of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, China）

出处： Journal of Hematology & Oncology 2021 Vol.14 No.1 P33

摘要： An amendment to this paper has been published and can be accessed via the original article.

[外文期刊] P20.02 To Evaluate the Efficacy and Optimal Timing of Postoperative Radiotherapy in Completely Resected stage IIIA(N2) Non-Small Cell Lung Cancer SCIE SCI

作者： W. Feng¹;X. Fu¹;X. Cai¹;J. Liu¹;D. Hu²;Y. Xu³;Z. Zhu⁴;S. Zhao⁵;Y. Bai⁶;J. He⁷;T. Chen⁸ （1 Department of Radiation Oncology, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai/CN; 2 Department of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai/CN; 3 Department of Radiation Oncology, Shanghai Pulmonary Hospital, Shanghai/CN; 4 Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai/CN; 5 Department of Radiation Oncology, Ruijin Hospital, Affiliated To Shanghai Jiaotong University, School of Medicine, Shanghai/CN; 6 Department of Radiation Oncology, Renji Hospital, Affiliated To Shanghai Jiaotong University, School of Medicine, Shanghai/CN; 7 Department of Radiation Oncology, Zhongshan Hospital Fudan University, Shanghai/CN; 8 Department of Radiation Oncology, Shanghai First People’s Hospital, Affiliated To Shanghai Jiaotong University, Shanghai/CN）

出处： Journal of Thoracic Oncology 2021 Vol.16 No.3Suppl PS360-S361

[外文期刊] Optimized protocol for an inducible rat model of liver tumor with chronic hepatocellular injury, inflammation, fibrosis, and cirrhosis SCIE

作者： Zhiao Chen¹, Shengli Li², Leng Han³, Xianghuo He¹ （Affiliations 1 Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai 200032, China. 2 Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, China. 3 Department of Biochemistry and Molecular Biology, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.）

出处： STAR protocols 2021 Vol.2 No.1 P100353

关键词： Cancer;Genetics;Model organisms.

摘要： Animal models of liver cancer are instrumental in the study of hepatocarcinogenesis and development of novel therapeutic approaches. Here, we describe ...

[外文期刊] Noble Metal Nanomaterials for NIR-Triggered Photothermal Therapy in Cancer SCIE SCI EI

作者： Zhuoqian Lv¹, Sijia He², Youfu Wang¹, Xinyuan Zhu¹ （Affiliations 1 School of Chemistry and Chemical Engineering, Frontiers Science Center for Transformative Molecules, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, 200240, China. 2 Molecular Diagnostic Laboratory of Cancer Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 650 Xinsongjiang Road, Shanghai, 201620, China.）

出处： Advanced healthcare materials 2021 Vol.10 No.6 Pe2001806

关键词： cancer therapy;light penetration;noble metal nanomaterials;photothermal therapy;surface plasmon resonance.

摘要： It is of great significance to develop anticancer therapeutic agents or technologies with high degree of specificity and patient compliance, while low ...

[外文期刊] Biobanked human foreskin epithelial cell sheets reduce inflammation and promote wound healing in a nude mouse model

作者： Dongliang Zhang;Jialiang Shao;Jingming Zhuang;Shukui Zhou;Shuo Yin;Fuyue Wu;Jiangang Hou;Xiang Wang （Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China Department of Urology, Huashan Hospital, FuDan University, Shanghai, China Department of Urology, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China Remed Regenerative Medicine Clinical Application Institute, Shanghai, China）

出处： BMC Biotechnology 2021 Vol.21 No.1 P1-14

关键词： Epithelial cell sheets;Human foreskin;Programmed cryopreservation;Refrigerated storage;Biobanking;Fructose;Inflammation;Wound healing

摘要： Background Human epithelial cell sheets (ECSs) are used to clinically treat epithelial conditions such as burns, corneal blindness, middle ear choles ...

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