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[外文期刊] A novel surgical technique of internal limiting membrane peeling for high myopic foveoschisis: a wide range of whole piece consecutive peeling without preservation of epi-fovea SCIE SCI

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作者： Shuai He;Tong Su;Zhong-Yi Zhou;Xiao-Meng Li;Wu Xu;Qing-Hua Qiu （Qing-Hua Qiu. Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 100 Haining Road, Hongkou District, Shanghai 200080, China. qinghuaqiu@163.com;Wu Xu. School of Aeronautics and Astronautics, Shanghai Jiao Tong University, Shanghai 200241, China. xuwu@sjtu.edu.cn Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China;National Clinical Research Center for Eye Diseases Shanghai Key Laboratory of Ocular Fundus Diseases Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China;National Clinical Research Center for Eye Diseases Shanghai Key Laboratory of Ocular Fundus Diseases Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China;National Clinical Research Center for Eye Diseases;Shanghai Engineering Center for Visual Science and Photomedicine）

出处： International Journal of Ophthalmology 2022 Vol.15 No.2 P284-290

关键词： high myopic foveoschisis;internal limiting membrane peeling;surgical technique;macular hole

摘要： AIM: To demonstrate an improved surgical technique of whole piece consecutive internal limiting membrane (ILM) peeling without preservation of the epi ...

[外文期刊] Factors Associated with Progression of Different Prediabetic Status to Diabetes: A Community-based Cohort Study

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作者： Na Li¹, Chunhua Lu², Yuhang Ma¹, Xuejiao Wang¹, Yunxia Ling¹, Yanhua Yin¹, Shumei Li³, Jiao Huang¹, Lihua Yu², Weiping Dong¹, Huichen He⁴, Mei Kang⁴, Lei Ma⁴, Mingyu Gu¹, Li Zhao¹, Yunhong Huang¹, Fang Liu¹, Yufan Wang¹, Xianying Gai⁵, Junyi Jiang⁶, Yongde Peng⁷, Xiaoying Ding⁸ （Affiliations 1 Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. 2 Community Health Service Center of Sijing, Songjiang District, Shanghai 201601, China. 3 Department of Endocrinology and Metabolism, Shanghai Fourth People\'s Hospital, School of Medicine, Tongji University, Shanghai 200434, China. 4 Clinical Research Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. 5 Department of Endocrinology, Sijing Hospital, Songjiang District, Shanghai 201601, China. 6 Department of Clinical Pharmacology, Xiangya Hospital, Central South University and Institute of Clinical Pharmacology, Central South University, Hunan Key Laboratory of Pharmacogenetics, Changsha 410008, PR China. Electronic address: jiangjy@live.cn. 7 Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. Electronic address: pengyongde0908@126.com. 8 Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. Electronic address: xiaoyingding@126.com.）

出处： Diabetes research and clinical practice 2022 P109193

关键词： combined glucose intolerance (CGI);insulin resistance;insulin secretion;prediabetes;progress.

摘要： Aims: To examine the predictive factors associated with the progression of different prediabetic status to diabetes. Methods: A two-year retrospective ...

[外文期刊] TOP2A promotes proliferation and metastasis of hepatocellular carcinoma regulated by miR-144-3p SCIE SCI

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作者： Tao Wang^{1 2}, Jing Lu¹, Rangrang Wang¹, Wanyue Cao¹, Junming Xu¹ （Affiliations 1 Department of General Surgery, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200080, China. 2 Department of General Surgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.）

出处： Journal of Cancer 2022 Vol.13 No.2 P589-601

关键词： EMT;Hepatocellular carcinoma;TOP2A;cell cycle;miR-144-3p.

摘要： Topoisomerase II alpha (TOP2A) is an important nuclear protein which is found in various types of cancers. Whether TOP2A plays an important role in he ...

[外文期刊] Predicting Clear Cell Renal Cell Carcinoma Survival Using Kurtosis of Cytoplasm in the Hematoxylin Channel from Histology Slides

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作者： Jun Wang¹, Jianhui Chen², Liren Jiang³, Qi Wu^{1 4}, Dawei Wang⁵ （Affiliations 1 Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. 2 Department of Medical Oncology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China. 3 Department of Pathology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. 4 Department of Urology, The Sixth Affiliated Hospital of Wenzhou Medical University (The People\'s Hospital of Lishui), Wenzhou, Zhejiang 323000, China. 5 Department of Urology, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, China.）

出处： Journal of oncology 2022 Vol.2022 P7693993

摘要： Purpose: Grade-dependent decrease of lipid storage in clear cell renal cell carcinoma (ccRCC) leads to morphology changes in HE sections. This study i ...

[外文期刊] Leukemia inhibitory factor receptor homodimerization mediated by acetylation of extracellular lysine promotes prostate cancer progression through the PDPK1/AKT/GCN5 axis

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作者： Yufeng Ding¹, Jialiang Shao², Tiezhu Shi², Hua Yu¹, Xiang Wang², Honggang Chi³, Xiongjun Wang¹ （Affiliations 1 School of Life Sciences, Guangzhou University, Guangzhou, China. 2 Department of Urology, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, China. 3 Department of Traditional Chinese Medicine, The First Dongguan Affiliated Hospital of Guangdong Medical University, Dongguan, China.）

出处： Clinical and translational medicine 2022 Vol.12 No.2 Pe676

摘要： Background: Prostate cancer (PCa), an inert tumour, has a long progression period, but valid biomarkers and methods for effectively and sensitively mo ...

[外文期刊] Cerebrospinal Fluid Extracellular Vesicles with Distinct Properties in Autoimmune Encephalitis and Herpes Simplex Encephalitis

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作者： Yongang Li¹, Jiachen Gu², Youbing Mao³, Xijia Wang¹, Zongshan Li⁴, Xiaomin Xu⁴, Huimin Chen⁴, Yaxing Gui⁵ （Affiliations 1 Department of Neurology, The First People\'s Hospital of Wenling, Wenling, China. 2 Department of Neurology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No.86 Wujin Road, Shanghai, 200080, China. 3 Department of Neuroelectrophysiology, The First People\'s Hospital of Wenling, Wenling, China. 4 Department of Neurology, School of Medicine, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, China. 5 Department of Neurology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No.86 Wujin Road, Shanghai, 200080, China. YaxingGui@shsmu.edu.cn.）

出处： Molecular neurobiology 2022

关键词： Autoimmune encephalitis (AE);Exosomes;Herpes simplex encephalitis (HSE);microRNAs.

摘要： Encephalitis mediated by autoantibodies against neuronal antigens and herpes simplex encephalitis (HSE) are seemingly separate causes of encephalopath ...

[外文期刊] Metal–Phenolic-Network-Coated Dendrimer–Drug Conjugates for Tumor MR Imaging and Chemo/Chemodynamic Therapy via Amplification of Endoplasmic Reticulum Stress

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作者： Zhiqiang Wang, Yunqi Guo, Yu Fan, Jingwen Chen, Han Wang, Mingwu Shen, Xiangyang Shi （1 State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai, 201620 China; 2 Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080 China）

出处： Advanced Materials 2022 Vol.34 No.7 P2107009

关键词： amplification of endoplasmic reticulum stress;chemo/chemodynamic therapy;dendrimers;iron–tannic acid networks;toyocamycin

摘要： Amplification of endoplasmic reticulum stress (ERS) to realize enhanced cancer therapy has been considered to be unique in current cancer nanomedicine ...

[外文期刊] Cost-Utility Analysis of Once-Weekly Semaglutide, Dulaglutide, and Exenatide for Type 2 Diabetes Patients Receiving Metformin-Based Background Therapy in China SCIE SCI

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作者： Shanshan Hu¹, Shuowen Wang¹, Chendong Qi¹, Shengying Gu¹, Chenyang Shi¹, Lin Mao¹, Guorong Fan¹ （Affiliation 1 Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： Frontiers in pharmacology 2022 Vol.13 P831364

关键词： UKPDS OM;cost-utility analysis;dulaglutide;extended-release exenatide;once-weekly GLP-1 receptor agonist;subcutaneous semaglutide;type 2 diabetes.

摘要： Introduction: The substantial financial burden associated with type 2 diabetes (T2D) over a lifetime cannot be neglected. Therefore, the objective of ...

[外文期刊] Targeting Protein Kinase C for Cancer Therapy

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作者： Sijia He¹, Qi Li¹, Qian Huang¹, Jin Cheng¹ （Affiliation 1 Cancer Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, China.）

出处： Cancers 2022 Vol.14 No.5 P1104

关键词： cancer;cell death;protein kinase C;targeted therapy.

摘要： Protein kinase C (PKC) isoforms, a group of serine-threonine kinases, are important regulators in carcinogenesis. Numerous studies have demonstrated t ...

[外文期刊] Schisandrol A, the main active ingredient of Schisandrae Chinensis Fructus, inhibits pulmonary fibrosis through suppression of the TGF-β signaling pathway as revealed by UPLC-Q-TOF/MS, network pharmacology and experimental verification

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作者： Zhenghua Wu¹, Mengqi Jia², Wenjuan Zhao³, Xucong Huang⁴, Xinyi Yang⁵, Dongxin Chen⁶, Xijier Qiaolongbatu⁷, Xiaojing Li⁸, Jiaqi Wu⁹, Feng Qian¹⁰, Yuefen Lou¹¹, Guorong Fan¹² （Affiliations 1 Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, PR China. Electronic address: wuzhenghua526@163.com. 2 Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, PR China. Electronic address: 346852884@qq.com. 3 School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, PR China. Electronic address: zhaowj@sjtu.edu.cn. 4 School of Pharmacy, Chongqing Medical University, Chongqing, 400016, PR China. Electronic address: 1109060643@qq.com. 5 School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, PR China. Electronic address: Xinyi2017@sjtu.edu.cn. 6 School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, PR China. Electronic address: 770512829doudou@sjtu.edu.cn. 7 School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, PR China. Electronic address: 962689538@qq.com. 8 Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, PR China. Electronic address: l_xiaojing@yeah.net. 9 Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, PR China. Electronic address: wjq731030@126.com. 10 School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, PR China. Electronic address: fengqian@sjtu.edu.cn. 11 Department of Pharmacy, Shanghai Fourth People\'s Hospital Affiliated to Tongji University School of Medicine, Shanghai, 200434, PR China. Electronic address: louyuefen@sina.cn. 12 Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, PR China. Electronic address: fanguorong@sjtu.edu.cn.）

出处： Journal of ethnopharmacology 2022 Vol.289 P115031

关键词： Idiopathic pulmonary fibrosis;Network pharmacology;Schisandra chinensis;Schisandrol A;TGF-β signaling pathway;UPLC-Q-TOF/MS.

摘要： Ethnopharmacological relevance: Schisandra chinensis decoction derived from the book of Waitai Miyao (Tao Wang, Tang dynasty) is often used in the tre ...