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作者: Shuai He;Tong Su;Zhong-Yi Zhou;Xiao-Meng Li;Wu Xu;Qing-Hua Qiu (Qing-Hua Qiu. Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 100 Haining Road, Hongkou District, Shanghai 200080, China. qinghuaqiu@163.com;Wu Xu. School of Aeronautics and Astronautics, Shanghai Jiao Tong University, Shanghai 200241, China. xuwu@sjtu.edu.cn Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China;National Clinical Research Center for Eye Diseases Shanghai Key Laboratory of Ocular Fundus Diseases Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China;National Clinical Research Center for Eye Diseases Shanghai Key Laboratory of Ocular Fundus Diseases Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China;National Clinical Research Center for Eye Diseases;Shanghai Engineering Center for Visual Science and Photomedicine)

出处: International Journal of Ophthalmology 2022 Vol.15 No.2 P284-290

关键词: high myopic foveoschisis;internal limiting membrane peeling;surgical technique;macular hole

摘要: AIM: To demonstrate an improved surgical technique of whole piece consecutive internal limiting membrane (ILM) peeling without preservation of the epi ...

作者: Na Li  1, Chunhua Lu  2, Yuhang Ma  1, Xuejiao Wang  1, Yunxia Ling  1, Yanhua Yin  1, Shumei Li  3, Jiao Huang  1, Lihua Yu  2, Weiping Dong  1, Huichen He  4, Mei Kang  4, Lei Ma  4, Mingyu Gu  1, Li Zhao  1, Yunhong Huang  1, Fang Liu  1, Yufan Wang  1, Xianying Gai  5, Junyi Jiang  6, Yongde Peng  7, Xiaoying Ding  8 (Affiliations 1 Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. 2 Community Health Service Center of Sijing, Songjiang District, Shanghai 201601, China. 3 Department of Endocrinology and Metabolism, Shanghai Fourth People\'s Hospital, School of Medicine, Tongji University, Shanghai 200434, China. 4 Clinical Research Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. 5 Department of Endocrinology, Sijing Hospital, Songjiang District, Shanghai 201601, China. 6 Department of Clinical Pharmacology, Xiangya Hospital, Central South University and Institute of Clinical Pharmacology, Central South University, Hunan Key Laboratory of Pharmacogenetics, Changsha 410008, PR China. Electronic address: jiangjy@live.cn. 7 Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. Electronic address: pengyongde0908@126.com. 8 Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. Electronic address: xiaoyingding@126.com.)

出处: Diabetes research and clinical practice 2022 P109193

关键词: combined glucose intolerance (CGI);insulin resistance;insulin secretion;prediabetes;progress.

摘要: Aims: To examine the predictive factors associated with the progression of different prediabetic status to diabetes. Methods: A two-year retrospective ...

作者: Tao Wang  1   2, Jing Lu  1, Rangrang Wang  1, Wanyue Cao  1, Junming Xu  1 (Affiliations 1 Department of General Surgery, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200080, China. 2 Department of General Surgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.)

出处: Journal of Cancer 2022 Vol.13 No.2 P589-601

关键词: EMT;Hepatocellular carcinoma;TOP2A;cell cycle;miR-144-3p.

摘要: Topoisomerase II alpha (TOP2A) is an important nuclear protein which is found in various types of cancers. Whether TOP2A plays an important role in he ...

作者: Jun Wang  1, Jianhui Chen  2, Liren Jiang  3, Qi Wu  1   4, Dawei Wang  5 (Affiliations 1 Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. 2 Department of Medical Oncology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China. 3 Department of Pathology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. 4 Department of Urology, The Sixth Affiliated Hospital of Wenzhou Medical University (The People\'s Hospital of Lishui), Wenzhou, Zhejiang 323000, China. 5 Department of Urology, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, China.)

出处: Journal of oncology 2022 Vol.2022 P7693993

摘要: Purpose: Grade-dependent decrease of lipid storage in clear cell renal cell carcinoma (ccRCC) leads to morphology changes in HE sections. This study i ...

作者: Yufeng Ding  1, Jialiang Shao  2, Tiezhu Shi  2, Hua Yu  1, Xiang Wang  2, Honggang Chi  3, Xiongjun Wang  1 (Affiliations 1 School of Life Sciences, Guangzhou University, Guangzhou, China. 2 Department of Urology, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, China. 3 Department of Traditional Chinese Medicine, The First Dongguan Affiliated Hospital of Guangdong Medical University, Dongguan, China.)

出处: Clinical and translational medicine 2022 Vol.12 No.2 Pe676

摘要: Background: Prostate cancer (PCa), an inert tumour, has a long progression period, but valid biomarkers and methods for effectively and sensitively mo ...

作者: Yongang Li  1, Jiachen Gu  2, Youbing Mao  3, Xijia Wang  1, Zongshan Li  4, Xiaomin Xu  4, Huimin Chen  4, Yaxing Gui  5 (Affiliations 1 Department of Neurology, The First People\'s Hospital of Wenling, Wenling, China. 2 Department of Neurology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No.86 Wujin Road, Shanghai, 200080, China. 3 Department of Neuroelectrophysiology, The First People\'s Hospital of Wenling, Wenling, China. 4 Department of Neurology, School of Medicine, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, China. 5 Department of Neurology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No.86 Wujin Road, Shanghai, 200080, China. YaxingGui@shsmu.edu.cn.)

出处: Molecular neurobiology 2022

关键词: Autoimmune encephalitis (AE);Exosomes;Herpes simplex encephalitis (HSE);microRNAs.

摘要: Encephalitis mediated by autoantibodies against neuronal antigens and herpes simplex encephalitis (HSE) are seemingly separate causes of encephalopath ...

作者: Zhiqiang Wang, Yunqi Guo, Yu Fan, Jingwen Chen, Han Wang, Mingwu Shen, Xiangyang Shi (1 State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai, 201620 China; 2 Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080 China)

出处: Advanced Materials 2022 Vol.34 No.7 P2107009

关键词: amplification of endoplasmic reticulum stress;chemo/chemodynamic therapy;dendrimers;iron–tannic acid networks;toyocamycin

摘要: Amplification of endoplasmic reticulum stress (ERS) to realize enhanced cancer therapy has been considered to be unique in current cancer nanomedicine ...

作者: Shanshan Hu  1, Shuowen Wang  1, Chendong Qi  1, Shengying Gu  1, Chenyang Shi  1, Lin Mao  1, Guorong Fan  1 (Affiliation 1 Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.)

出处: Frontiers in pharmacology 2022 Vol.13 P831364

关键词: UKPDS OM;cost-utility analysis;dulaglutide;extended-release exenatide;once-weekly GLP-1 receptor agonist;subcutaneous semaglutide;type 2 diabetes.

摘要: Introduction: The substantial financial burden associated with type 2 diabetes (T2D) over a lifetime cannot be neglected. Therefore, the objective of ...

作者: Sijia He  1, Qi Li  1, Qian Huang  1, Jin Cheng  1 (Affiliation 1 Cancer Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, China.)

出处: Cancers 2022 Vol.14 No.5 P1104

关键词: cancer;cell death;protein kinase C;targeted therapy.

摘要: Protein kinase C (PKC) isoforms, a group of serine-threonine kinases, are important regulators in carcinogenesis. Numerous studies have demonstrated t ...

作者: Zhenghua Wu  1, Mengqi Jia  2, Wenjuan Zhao  3, Xucong Huang  4, Xinyi Yang  5, Dongxin Chen  6, Xijier Qiaolongbatu  7, Xiaojing Li  8, Jiaqi Wu  9, Feng Qian  10, Yuefen Lou  11, Guorong Fan  12 (Affiliations 1 Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, PR China. Electronic address: wuzhenghua526@163.com. 2 Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, PR China. Electronic address: 346852884@qq.com. 3 School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, PR China. Electronic address: zhaowj@sjtu.edu.cn. 4 School of Pharmacy, Chongqing Medical University, Chongqing, 400016, PR China. Electronic address: 1109060643@qq.com. 5 School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, PR China. Electronic address: Xinyi2017@sjtu.edu.cn. 6 School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, PR China. Electronic address: 770512829doudou@sjtu.edu.cn. 7 School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, PR China. Electronic address: 962689538@qq.com. 8 Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, PR China. Electronic address: l_xiaojing@yeah.net. 9 Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, PR China. Electronic address: wjq731030@126.com. 10 School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, PR China. Electronic address: fengqian@sjtu.edu.cn. 11 Department of Pharmacy, Shanghai Fourth People\'s Hospital Affiliated to Tongji University School of Medicine, Shanghai, 200434, PR China. Electronic address: louyuefen@sina.cn. 12 Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, PR China. Electronic address: fanguorong@sjtu.edu.cn.)

出处: Journal of ethnopharmacology 2022 Vol.289 P115031

关键词: Idiopathic pulmonary fibrosis;Network pharmacology;Schisandra chinensis;Schisandrol A;TGF-β signaling pathway;UPLC-Q-TOF/MS.

摘要: Ethnopharmacological relevance: Schisandra chinensis decoction derived from the book of Waitai Miyao (Tao Wang, Tang dynasty) is often used in the tre ...

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