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作者: J. Ren1;B. Guo1;H. Sui2,3;J. Chen1;L. Zhang2,4;C. Lv1;B. Li1CA1 (1 Changhai Hospital of Traditional Chinese Medicine, Naval Medical University, 200433, Shanghai, China; 2 Department of Medical Oncology and Cancer Institute of Integrative Medicine, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, 201203, Shanghai, China; 3 Medical Experiment Center, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 201803, Shanghai, China; 4 Department of Integrated Chinese and Western Medicine, Henan Provincial Cancer Hospital, Affiliated Tumor Hospital of Zhengzhou University, Zhengzhou, China)

出处: Clinical and Translational Oncology 2022 Vol.24 No.2 P305-318

关键词: Apc Min/ +;+ Mice;Aerobic exercise;Intestinal tumor;Flora;Prevention

摘要: Introduction Intestinal tumor is one of the most common tumors that seriously threaten the health of residents all over the world. Studies suggest th ...

作者: Xiangyu Zou1;Sihao Lin2;Liang Zhong1;Jie Liu3;Yu Meng4CA1;Yingjian Zhu2CA2;Jie Sun1CA3 (1 Department of Urology, Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of Medicine, 1678, Dongfang road, 200127, Shanghai, China; 2 Department of Urology, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 800 Huangjiahuayuan Road, 201803, Shanghai, China; 3 Department of Neurology, Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of Medicine, 1678, Dongfang road, 200127, Shanghai, China; 4 Department of Nephrology, The First Hospital Affiliated to Jinan University, 510630, Guangzhou, China)

出处: Clinical and Experimental Nephrology 2022 Vol.26 No.1 P13-21

关键词: Renal denervation;Ischemic–reperfusion injury;miRNA;Fibrosis

摘要: Background Renal denervation (RDN) has been used to promote kidney injury repair, whereas miRNAs have been found to be involved in the pathophysiolog ...

作者: Wang, Xuejun1;Su, Jinwen2;Lin, Zhikang1;Liu, Kangyong3;Zhuang, Yu4 (1 Department of Cardiology, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai 201318, P.R. China 2 Department of Cardiology, Shanghai Ninth People\'s Hospital Affiliated to Shanghai JiaoTong University School of Medicine, Shanghai 200011, P.R. China 3 Department of Neurology, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai 201318, P.R. China 4 Department of Cardiovascular Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, P.R. China)

出处: Experimental & Therapeutic Medicine 2022 Vol.23 No.1

关键词: cardiomyopathy;HL1 cell line;myocardial infarction;NF-κB signaling pathway;particularly interesting new cysteine histidine rich 1

摘要: Myocardial infarction (MI), the leading cause of death among patients with cardiovascular diseases, is characterized by acute cardiac muscle injury du ...

作者: Yi Zheng, Xin Li, Caihong Dong, Li Ding, Hui Huang, Tianhu Zhang, Yu Chen, Rong Wu (1 Department of Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080 P. R. China; 2 Department of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai, 200032 P. R. China; 3 Education Institute, Tongji University School of Medicine, Tongji University Cancer Center, Shanghai Engineering Research Center of Ultrasound Diagnosis and Treatment, National Clinical Research Center of Interventional Medicine, Shanghai, 200072 P. R. China; 4 Shanghai Engineering Research Center of Organ Repair, Materdicine Lab, School of Life Sciences, Shanghai University, Shanghai, 200444 P. R. China)

出处: Advanced Functional Materials 2022 Vol.32 No.4 P2107529

关键词: ferroptosis;nanocatalytic therapy;synergistic therapy;tumor drug resistance;ultrasound nanomedicine

摘要: Inducing ferroptosis has been acknowledged as an emerging strategy to kill drug-resistant tumor cells, but how to efficiently induce ferroptosis at th ...

作者: Gao Gang1,2;Chen Xinwei1;Chen LiXiao1;Zhang Yu1;Zhang Cheng1;Dong Pin1CA1 (1 Department of Otorhinolaryngology Head and Neck Surgery, Shanghai General Hospital of Nanjing Medical University, 200080, Shanghai, China; 2 Department of Otorhinolaryngology Head and Neck Surgery, The First People’s Hospital of Nantong, 226001, Nantong, China)

出处: European Archives of Oto-Rhino-Laryngology 2022 Vol.279 No.3 P1473-1479

关键词: Lymphovascular invasion;Hypopharyngeal squamous cell carcinoma;Clinicopathologic;Risk factors;Prognosis

摘要: Purpose Lymphatic vascular invasion (LVI) is a poor prognostic factor for hypopharyngeal squamous cell carcinoma (HPSCC), but the risk factors of LVI ...

作者: Jing Wang1,2;Zuopeng Wang1,2;Weihong Lin1;Qilei Han1;Hanlei Yan1;Wei Yao1;Rui Dong1;Deshui Jia3CA1;Kuiran Dong1CA2;Kai Li1CA3 (1 Department of Pediatric Surgery, Children’s Hospital of Fudan University, National Children’s Medical Center, 399 Wanyuan Road, Shanghai 201102, China; 2 These authors contributed equally; 3 Laboratory of Cancer Genomics and Biology, Department of Urology, and Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China)

出处: Molecular Therapy - Oncolytics 2022 Vol.24 P834-848

关键词: neuroblastoma;pediatric cancer;long non-coding RNA;LINC01296;NCL;SOX11

摘要: Neuroblastoma (NB) is the most common extracranial solid tumor in childhood. Long non-coding RNA LINC01296 has been shown to predict the invasiveness ...

作者: Li-Li Zhang;Li-Li Zhang;Li-Li Zhang;Liang Zhang;Jingde Dong;Ying Zhao;Xiao-Ping Wang (Shanghai General Hospital of Nanjing Medical University, Shanghai, China Department of Geriatrics, Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China Department of Neurology, Affiliated Hospital of Jiangnan University, Wuxi, China Department of Geriatrics, Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China Department of Geriatrics, Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China Department of Geriatrics, Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China Shanghai General Hospital of Nanjing Medical University, Shanghai, China)

出处: Frontiers in Neurology 2022 Vol.13

关键词: Parkinson\'s disease;freezing of gait;motor symptoms;non-motor symptoms;malnutrition

摘要: Background and PurposeLittle is known about the nutritional status and clinical characteristics of patients with Parkinson\'s disease with freezing of ...

作者: Dawei Li1,2,3;Guoke Tang4,3;Hui Yao5,3;Yuqi Zhu5;Changgui Shi6;Qiang Fu4CA1;Fei Yang2,7CA2;Xing Wang2,7CA3 (1 Senior Department of Orthopedics, The Fourth Medical Center of PLA General Hospital, Beijing, 100091, China; 2 Beijing National Laboratory for Molecular Sciences, State Key Laboratory of Polymer Physics & Chemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China; 3 These authors have contributed equally to this work.; 4 Department of Orthopedics, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, 200080, China; 5 Department of Orthopedics, Eye Hospital China Academy of Chinese Medical Sciences, Beijing, 100040, China; 6 Department of Orthopedics, Second Affiliated Hospital of Naval Medical University, Shanghai, 20003, China; 7 University of Chinese Academy of Sciences, Beijing, 100049, China)

出处: Bioactive Materials 2022

关键词: pH-responsive prodrug;PEGylated;Programmable drug release;Schiff base;Antibacterial activity

摘要: In the current global crisis of antibiotic resistance, delivery systems are emerging to combat resistant bacteria in a more efficient manner. Despite ...

作者: Lucas S Aparicio1,2;Qi-Fang Huang3;Jesus D Melgarejo2;Dong-Mei Wei2;Lutgarde Thijs2;Fang-Fei Wei2,4;Natasza Gilis-Malinowska5;Chang-Sheng Sheng3;José Boggia6;Teemu J Niiranen7,8;Augustine N Odili9;Katarzyna Stolarz-Skrzypek10;Jessica Barochiner1;Daniel Ackermann11;Kalina Kawecka-Jaszcz10;Valérie Tikhonoff12;Zhen-Yu Zhang2;Edoardo Casiglia12;Krzysztof Narkiewicz5;Jan Filipovský13;Aletta E Schutte14,15;Wen-Yi Yang2,16;Antti M Jula7;Angela J Woodiwiss17;Murielle Bochud18;Gavin R Norton17;Ji-Guang Wang3;Yan Li3;Jan A Staessen19,20CA;International Database of Central Arterial Properties for Risk Stratification (IDCARS) Investigators (1 Servicio de Clínica Médica, Sección Hipertensión Arterial, Hospital Italiano de Buenos Aires , Buenos Aires , Argentina; 2 Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven , Leuven , Belgium; 3 Center for Epidemiological Studies and Clinical Trials and Center for Vascular Evaluations, Shanghai Key Laboratory of Hypertension, Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine , Shanghai , China; 4 Department of Cardiology, the First Affiliated Hospital of Sun Yat-Sen University , Guangzhou, Guangdong , China; 5 Hypertension Unit, Department of Hypertension and Diabetology, Medical University of Gdańsk , Gdańsk , Poland; 6 Centro de Nefrología and Departamento de Fisiopatología, Hospital de Clínicas, Universidad de la República , Montevideo , Uruguay; 7 Department of Chronic Disease Prevention, Finnish Institute for Health and Welfare , Turku , Finland; 8 Department of Medicine, University of Turku and Turku University Hospital , Turku , Finland; 9 Department of Internal Medicine, Faculty of Clinical Sciences, College of Health Sciences, University of Abuja , Abuja , Nigeria; 10 First Department of Cardiology, Interventional Electrocardiology and Hypertension, Jagiellonian University Medical College , Kraków , Poland; 11 Clinic for Nephrology and Hypertension, Inselspital, Bern University Hospital and University of Bern , Bern , Switzerland; 12 Department of Medicine, University of Padua , Padua , Italy; 13 Faculty of Medicine, Charles University , Pilsen , Czech Republic; 14 Hypertension in Africa Research Team (HART), South African Medical Research Council and Unit of Hypertension and Cardiovascular Disease, North-West University , Potchefstroom , South Africa; 15 School of Population Health, University of New South Wales, The George Institute for Global Health , Sydney , Australia; 16 Department of Cardiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai , China; 17 Cardiovascular Pathophysiology and Genomics Research Unit, Schools of Physiology, Faculty of Health Sciences, University of the Witwatersrand , Johannesburg , South Africa; 18 Institute of Social and Preventive Medicine, University Hospital of Lausanne , Lausanne , Switzerland; 19 Research Institute Alliance for the Promotion of Preventive Medicine , Mechelen , Belgium; 20 Biomedical Sciences Group, Faculty of Medicine, University of Leuven , Leuven , Belgium)

出处: American Journal of Hypertension 2022 Vol.35 No.1 P54-64

关键词: blood pressure;cardiovascular outcome;central blood pressure;hemodynamics;hypertension;pulse wave analysis;pulse wave velocity

摘要: OBJECTIVE To address to what extent central hemodynamic measurements, improve risk stratification, and determine outcome-based diagnostic thresholds, ...

作者: Yiming Li;Yiming Li;Zhenjiang Li;Jiaxuan Feng;Rui Feng;Jian Zhou;Zaiping Jing (Department of Cardiology, General Hospital of Northern Theater Command, Shenyang, China Endovascular Diagnosis and Treatment Center for Aortic Diseases, Department of Vascular Surgery, Changhai Hospital, Navy Medical University, Shanghai, China Department of Vascular Surgery, The First Affiliated Hospital of the Medical School of Zhejiang University, Hangzhou, China Endovascular Diagnosis and Treatment Center for Aortic Diseases, Department of Vascular Surgery, Changhai Hospital, Navy Medical University, Shanghai, China Department of Vascular Surgery, Shanghai General Hospital, Affiliated to Shanghai Jiaotong University, Shanghai, China Endovascular Diagnosis and Treatment Center for Aortic Diseases, Department of Vascular Surgery, Changhai Hospital, Navy Medical University, Shanghai, China Endovascular Diagnosis and Treatment Center for Aortic Diseases, Department of Vascular Surgery, Changhai Hospital, Navy Medical University, Shanghai, China)

出处: Frontiers in Cardiovascular Medicine 2022 Vol.9

关键词: aortic dissection (AD);novel procedure;endovascular treatment;vascular remodeling;thrombosis

摘要: AimNotwithstanding that unprecedented endovascular progress has been achieved in recent years, it remains unclear what is the best strategy to preserv ...

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