作者： Tianwei Qian ^{#  1   2   3   4   5   6}, Qiaoyun Gong ^{#  1   2   3   4   5}, Hangqi Shen  ^{1   2   3   4   5}, Caihua Li  ⁷, Gao Wang  ⁶, Xun Xu  ^{1   2   3   4   5}, Isabelle Schrauwen  ⁸, Weijun Wang  ^{9   10   11   12   13} （Affiliations 1 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, No. 100 Haining Rd, Shanghai, 200080, China. 2 National Clinical Research Center for Eye Diseases, Shanghai, China. 3 Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai, China. 4 Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China. 5 Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Disease, Shanghai, China. 6 Department of Neurology, Columbia University Medical Center, 630W 168th St, New York, 10032, USA. 7 Genesky Biotechnologies Inc, Shanghai, China. 8 Department of Neurology, Columbia University Medical Center, 630W 168th St, New York, 10032, USA. is2632@cumc.columbia.edu. 9 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, No. 100 Haining Rd, Shanghai, 200080, China. weij719@126.com. 10 National Clinical Research Center for Eye Diseases, Shanghai, China. weij719@126.com. 11 Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai, China. weij719@126.com. 12 Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China. weij719@126.com. 13 Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Disease, Shanghai, China. weij719@126.com.）

出处： BMC ophthalmology 2022 Vol.22 No.1 P69

关键词： Frameshift deletion;Fundus albipunctatus;Missense variants;RDH5 gene.

摘要： Background: The aim of this study is to identify the genetic defects in a Chinese family with fundus albipunctatus. Methods: Complete ophthalmic exami ...

作者： Yupeng Xu  ^{1   2}, Junjie Deng  ², Bo Zhang  ¹, Xian Xu  ², Tianyu Cheng  ², Jingjing Wang  ¹, Shuyu Xiong  ², Mengli Luan  ¹, Haidong Zou  ^{1   2}, Xiangui He  ^{3   2}, Chun Tang  ³, Xun Xu  ^{1   2} （Affiliations 1 Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China. 2 Department of Ophthalmology, Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China. 3 Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China xianhezi@163.com tangchuntc@shsyf.com.）

出处： The British journal of ophthalmology 2022

关键词： epidemiology;ocular surface;optics and refraction;public health;visual pathway.

摘要： Background: Vision-dependent mechanisms play a role in myopia progression in childhood. Thus, we investigated the distribution of ocular and corneal h ...

作者： Weihua Chen  ¹, Weifeng Wang  ², Jun Zhang  ^{2   3}, Guoqiang Liao  ², Jie Bai  ^{2   3}, Bo Yang  ², Mingyue Tan  ^{4   5}, Hua Gong  ² （Affiliations 1 Department of Urology, Shanghai East Hospital, Tongji University, Shanghai 200120, China. 2 Department of Urology, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai 201318, China. 3 Graduate School, Shanghai University of Traditional Chinese Medicine, Shanghai 201318, China. 4 Department of Urology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. 5 Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.）

出处： Journal of oncology 2022 Vol.2022 P7985468

摘要： Traditional Chinese medicine (TCM) is widely used as an alternative therapy for cancer treatment in China. Glutamine catabolism plays an important rol ...

作者： Xuejun Wang  ¹, Jinwen Su  ², Zhikang Lin  ¹, Kangyong Liu  ³, Yu Zhuang  ⁴ （Affiliations 1 Department of Cardiology, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai 201318, P.R. China. 2 Department of Cardiology, Shanghai Ninth People\'s Hospital Affiliated to Shanghai JiaoTong University School of Medicine, Shanghai 200011, P.R. China. 3 Department of Neurology, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai 201318, P.R. China. 4 Department of Cardiovascular Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, P.R. China.）

出处： Experimental and therapeutic medicine 2022 Vol.23 No.1 P62

关键词： HL1 cell line;NF-κB signaling pathway;cardiomyopathy;myocardial infarction;particularly interesting new cysteine histidine rich 1.

摘要： Myocardial infarction (MI), the leading cause of death among patients with cardiovascular diseases, is characterized by acute cardiac muscle injury du ...

作者： Jingjing Wang  ¹, Hui Xie  ¹, Ian Morgan  ², Jun Chen  ¹, Chunxia Yao  ³, Jianfeng Zhu  ¹, Haidong Zou  ^{1   4}, Kun Liu  ⁴, Xun Xu  ^{1   4}, Xiangui He  ^{1   4} （Affiliations 1 Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai Vision Health Center and Shanghai Children Myopia Institute, Shanghai, China. 2 Division of Biochemistry and Molecular Biology, Research School of Biology, Australian National University, Canberra, ACT, Australia. 3 Songjiang Center for Disease Control and Prevention, Shanghai, China. 4 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, National Clinical Research Center for Eye Diseases, Center of Eye Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai, China.）

出处： Asia-Pacific journal of ophthalmology (Philadelphia, Pa.) 2022 Vol.11 No.1 P12-18

摘要： Purpose: To compare the accuracy for various screening tests and their combined uses for myopia screening among children and adolescents and explore a ...

作者： Xiaomin He  ¹, Shuaibing Wang  ¹, Jiahui Zhou  ¹, Dong Zhang  ², Yaoting Xue  ³, Xuxu Yang  ³, Lingbin Che  ⁴, Danyang Li  ¹, Shengwei Xiao  ⁵, Shanqiu Liu  ¹, Si Yu Zheng  ¹, Jintao Yang  ¹ （Affiliations 1 College of Materials Science& Engineering, Zhejiang University of Technology, Hangzhou 310014, P. R. China. 2 Department of Chemical, Biomolecular, and Corrosion Engineering, College of Engineering and Polymer Science, The University of Akron, Akron, Ohio 44325, United States. 3 Department of Engineering Mechanics, Zhejiang University, Hangzhou 310027, P. R. China. 4 Department of Orthopedics, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200080, China. 5 School of Pharmaceutical and Chemical Engineering, Taizhou University, Taizhou 318000, China.）

出处： ACS applied materials & interfaces 2022

关键词： Janus materials;bilayer hydrogels;hydrogel patches;soft actuators;wearable electronics.

摘要： Bilayer hydrogels are attracting tremendous attention for their capability to integrate several different functions on the two sides of the gel, that ...

作者： Xuejiao Wang  ¹, Ting Xu  ², Rui Liu  ², Guojun Wu  ³, Liping Gu  ¹, Yahui Zhang  ¹, Feng Zhang  ², Huaqing Fu  ², Yunxia Ling  ¹, Xiaohui Wei  ¹, Yunchen Luo  ¹, Jian Shen  ⁴, Liping Zhao  ^{2   3}, Yongde Peng  ¹, Chenhong Zhang  ², Xiaoying Ding  ¹ （Affiliations 1 Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 State Key Laboratory of Microbial Metabolism and Ministry of Education Key Laboratory of Systems Biomedicine, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China. 3 Department of Biochemistry and Microbiology and New Jersey Institute for Food, Nutrition, and Health, School of Environmental and Biological Sciences, Rutgers University, New Brunswick, NJ, United States. 4 Shanghai Centre for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, China.）

出处： Frontiers in endocrinology 2022 Vol.12 P806331

关键词： acarbose;clinical phenotype;dysbiosis;gut microbiota;high-fiber diet;polycystic ovary syndrome.

摘要： Objective: Gut microbial dysbiosis is associated with high heterogeneity of polycystic ovary syndrome (PCOS); however, studies about gut microbiota ta ...

作者： Mengdi Fu  ¹, Chengjuan Jin  ², Shuai Feng  ³, Zongyang Jia  ⁴, Lekai Nie  ⁴, Yang Zhang  ⁵, Jin Peng  ¹, Xia Wang  ¹, Hualei Bu  ¹, Beihua Kong  ¹ （Affiliations 1 Department of Gynecology and Obstetrics, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China. 2 Department of Obstetrics and Gynecology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. 3 Gynecological Oncology Department, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China. 4 Department of Obstetrics and Gynecology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, China. 5 Department of Radiology, Qilu Hospital, Shandong University, Jinan, China.）

出处： Frontiers in oncology 2022 Vol.11 P810099

关键词： BRCA;PARPi;neoadjuvant chemotherapy;primary debulking surgery;prognosis.

摘要： Background: Whether neoadjuvant chemotherapy (NAC) followed by interval debulking surgery (IDS) against primary debulking surgery (PDS) has a differen ...

作者： Nuo Yu^1,2;Wenzhi Tu^3,2;Pu Qiu¹;Qian Ren¹;Xuming Chen³;Meifang Zhu¹;Yong Liu³CA1;Zhigang Chen¹CA2 （1 State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, China; 2 These authors contributed equally to this work.; 3 Department of Radiation Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China）

出处： Nano Today 2022 Vol.43 P101427

关键词： Ultrasmall in nano;Cell membrane;Biodegradable;Phototherapy;X-ray therapy

摘要： The overall therapeutic output is significantly affected by the route of nanomedicines in vivo, including the successive steps of delivery, exogenous ...

作者： Rangrang Wang  ¹, Yang Zhang  ², Junwei Fan  ³, Zhaowen Wang  ³, Yuan Liu  ⁴ （Affiliations 1 Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Huadong Hospital Affiliated to Fudan University, Shanghai, Shanghai, China. 2 Huadong Hospital Affiliated to Fudan University, Shanghai, Shanghai, China. 3 Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 4 Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: paradisetong@163.com.）

出处： Transplantation proceedings 2022

摘要： Background: New-onset diabetes mellitus after transplantation (NODAT) is a leading cause of morbidity and mortality after heart transplantation (HT), ...