作者： Kepeng Ou  ¹, Youjian Li  ¹, Ling Liu  ², Hua Li  ², Katherine Cox  ³, Jiahui Wu  ⁴, Jian Liu  ³, Andrew D Dick  ⁵ （Affiliations 1 College of Pharmacy, National & Local Joint Engineering Research Center of Targeted and Innovative Therapeutics, IATTI, Chongqing University of Arts and Sciences, Chongqing, China; Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. 2 Department of Ophthalmology, Yongchuan Hospital, Chongqing Medical University, Chongqing, China. 3 Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. 4 Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People\'s Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China. 5 Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol; Institute of Ophthalmology, University College London, London; National Institute for Health Research Biomedical Research Centre, Moorfields Eye Hospital, London, UK.）

出处： Neural regeneration research 2022 Vol.17 No.9 P1919-1928

关键词： antioxidants;autophagy enhancers;complement inhibitors;exosomes;neuropeptides;neuroprotective agents;retinal degeneration;senolytics.

摘要： Retinal degeneration is a debilitating ocular complication characterized by the progressive loss of photoreceptors and other retinal neurons, which ar ...

作者： Shu Yang  ¹, Bing-Cheng Wu  ¹, Zhe Cheng  ², Lan Li  ³, Yuan-Ping Zhang  ⁴, Hui Zhao  ⁵, Han-Mei Zeng  ¹, Dong-Fang Qi  ¹, Zi-Yao Ma  ¹, Jian-Guo Li  ¹, Rui Han  ¹, Fang-Zhou Qu  ¹, Yan Luo  ⁶, Yi Liu  ⁷, Xiao-Lei Chen  ⁸, Hong-Mei Dai  ¹ （Affiliations 1 Department of Ophthalmology, The First Hospital of Kunming, Kunming, 650011 Yunnan Province, China. 2 Eye institute of Xiamen University, Xiamen, Fujian, China. 3 Department of Ophthalmology, The Calmette Affiliated Hospital of Kunming Medical University, Kunming, China. 4 Department of Ophthalmology, The Second Affiliated Hospital of Kunming Medical University, Kunming, China. 5 Department of Ophthalmology, Shanghai General Hospital (Shanghai First People\'s Hospital), Shanghai 200080, China. 6 Department of Pediatrics, The First Hospital of Kunming, Kunming, 650011 Yunnan Province, China. 7 Department of Otorhinolaryngology, The First Hospital of Kunming, Kunming, 650011 Yunnan Province, China. 8 Department of Endocrinology, The First Hospital of Kunming, Kunming, 650011 Yunnan Province, China.）

出处： Disease markers 2022 Vol.2022 P7550090

摘要： Objective: The aims of our experiment were to compare the microorganisms in meibomian gland secretions from patients with internal hordeolum before an ...

作者： Lijun Tang  ¹, Xiao Zhao  ², Shitong Li  ², Lina Huang  ², Jinbao Li  ², Lianhua Chen  ¹, Shiwei Huang  ² （Affiliations 1 Department of Anesthesiology, Shanghai General Hospital of Nanjing Medical University, Shanghai, China. 2 Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China.）

出处： Frontiers in medicine 2022 Vol.9 P717477

关键词： apnea duration;oxygen saturation;rapid sequence induction intubation;rocuronium;succinylcholine.

摘要： Objective: The present study aimed to evaluate the impact of 1.5 mg/kg succinylcholine or 1.2 mg/kg rocuronium, vs. 1.0 mg/kg succinylcholine on apnea ...

作者： Tang, Gang¹;Du, Yi¹;Guan, Haochen¹;Jia, Jieshuang¹;Zhu, Nan¹;Shi, Yuping¹;Rong, Shu¹;Yuan, Weijie¹ （1 Department of Nephrology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China）

出处： British Journal of Pharmacology 2022 Vol.179 No.1 P159-178

关键词： butyrate;db/db mice;diabetic nephropathy;FFA2;muscle atrophy

摘要： Background and Purpose: Muscle protein catabolism in patients with diabetic nephropathy (DN) results in striking loss of muscle proteins, which increa ...

作者： Dong Lin  ¹, Liang Wu  ¹, Jiang Fan  ¹ （Affiliation 1 Department of Thoracic Surgery, Shanghai General Hospital Shanghai Jiao Tong University School of Medicine, Shanghai, China.）

出处： JAMA surgery 2022

作者： Yingying Sun  ¹, Jie Jin  ², Aying Zhu  ¹, Hong Hu  ¹, Yingying Lu  ¹, Yue Zeng  ¹, Dadao Jing  ¹ （Affiliations 1 Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201600, People\'s Republic of China. 2 Department of Geriatrics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, People\'s Republic of China.）

出处： International journal of general medicine 2022 Vol.15 P1319-1328

关键词： first episode pancreatitis;infected pancreatic necrosis;low-density lipoprotein cholesterol;recurrent acute pancreatitis;risk factors.

摘要： Background: In recent years, the cure rate of acute pancreatitis (AP) has increased gradually, but the morbidity of recurrent acute pancreatitis (RAP) ...

作者： Xiao Shen  ^{1   2}, Guorong Fan  ¹, Gaolin Liu  ¹, Fan Wang  ³, Qi Li  ³, Xinyan Liu  ², Hong Zhu  ², Ying Zhu  ², Jiguang Lu  ², Shuowen Wang  ¹ （Affiliations 1 Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai. 2 Department of Pharmacy, Suzhou Kowloon Hospital, Shanghai Jiaotong University School of Medicine, Suzhou, Jiangsu Province. 3 Department of Oncology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China.）

出处： Anti-cancer drugs 2022 Vol.33 No.1 Pe802-e807

摘要： The incidence of lung cancer is increasing yearly worldwide, and targeted medicines are the main choice for lung cancer patients. However, there has b ...

作者： Weijun Shen¹;Xuan Zhao²;Shitong Li^1,3CA1 （1 Nanjing Medical University, Shanghai General Hospital, 200080, Shanghai, China; 2 Department of Anesthesiology, Tenth People’s Hospital of Tongji University, No 301 Middle Yan Chang Road, 200072, Shanghai, China; 3 Nanjing Medical University, Shanghai General Hospital, 200080, Shanghai, China）

出处： Inflammation 2022 Vol.45 No.1 P331-342

关键词： exosomes;sepsis;lung injury;circ-fryl;SIRT3.

摘要： Sepsis-induced lung injury is a clinical syndrome characterized by injury of alveolar epithelium cells (AECs). Previous investigations illustrate that ...

作者： Yongyi Xie ^{#  1}, Baoyi Liu ^{#  1}, Zhouwei Wu  ¹ （Affiliation 1 Department of Dermatology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, People\'s Republic of China.）

出处： Clinical, cosmetic and investigational dermatology 2022 Vol.15 P77-86

关键词： biomarker;metabolism;systemic lupus erythematosus.

摘要： Purpose: Skin involvement is the second most common symptom of systemic lupus erythematosus (SLE), and the prevention of skin lesion development might ...

作者： Xuhui Fan  ¹, Ni Xie  ², Jingwen Chen  ¹, Tiewen Li  ³, Rong Cao  ¹, Hongwei Yu  ¹, Meijuan He  ¹, Zilin Wang  ¹, Yihui Wang  ¹, Hao Liu  ⁴, Han Wang  ^{1   2   5}, Xiaorui Yin  ¹ （Affiliations 1 Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 Institution for Clinical Research, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 3 Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 4 Department of Research and Development, Yizhun Medical AI Technology Co. Ltd., Beijing, China. 5 Department of Radiology, Jiading Branch of Shanghai General Hospital, Shanghai, China.）

出处： Frontiers in oncology 2022 Vol.12 P839621

关键词： biological characteristics;magnetic resonance imaging;prostate cancer;radiomics;risk stratification.

摘要： Objectives: This study aims to develop and evaluate multiparametric MRI (MP-MRI)-based radiomic models as a noninvasive diagnostic method to predict s ...