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作者: Kepeng Ou  1, Youjian Li  1, Ling Liu  2, Hua Li  2, Katherine Cox  3, Jiahui Wu  4, Jian Liu  3, Andrew D Dick  5 (Affiliations 1 College of Pharmacy, National & Local Joint Engineering Research Center of Targeted and Innovative Therapeutics, IATTI, Chongqing University of Arts and Sciences, Chongqing, China; Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. 2 Department of Ophthalmology, Yongchuan Hospital, Chongqing Medical University, Chongqing, China. 3 Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. 4 Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People\'s Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China. 5 Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol; Institute of Ophthalmology, University College London, London; National Institute for Health Research Biomedical Research Centre, Moorfields Eye Hospital, London, UK.)

出处: Neural regeneration research 2022 Vol.17 No.9 P1919-1928

关键词: antioxidants;autophagy enhancers;complement inhibitors;exosomes;neuropeptides;neuroprotective agents;retinal degeneration;senolytics.

摘要: Retinal degeneration is a debilitating ocular complication characterized by the progressive loss of photoreceptors and other retinal neurons, which ar ...

作者: Shu Yang  1, Bing-Cheng Wu  1, Zhe Cheng  2, Lan Li  3, Yuan-Ping Zhang  4, Hui Zhao  5, Han-Mei Zeng  1, Dong-Fang Qi  1, Zi-Yao Ma  1, Jian-Guo Li  1, Rui Han  1, Fang-Zhou Qu  1, Yan Luo  6, Yi Liu  7, Xiao-Lei Chen  8, Hong-Mei Dai  1 (Affiliations 1 Department of Ophthalmology, The First Hospital of Kunming, Kunming, 650011 Yunnan Province, China. 2 Eye institute of Xiamen University, Xiamen, Fujian, China. 3 Department of Ophthalmology, The Calmette Affiliated Hospital of Kunming Medical University, Kunming, China. 4 Department of Ophthalmology, The Second Affiliated Hospital of Kunming Medical University, Kunming, China. 5 Department of Ophthalmology, Shanghai General Hospital (Shanghai First People\'s Hospital), Shanghai 200080, China. 6 Department of Pediatrics, The First Hospital of Kunming, Kunming, 650011 Yunnan Province, China. 7 Department of Otorhinolaryngology, The First Hospital of Kunming, Kunming, 650011 Yunnan Province, China. 8 Department of Endocrinology, The First Hospital of Kunming, Kunming, 650011 Yunnan Province, China.)

出处: Disease markers 2022 Vol.2022 P7550090

摘要: Objective: The aims of our experiment were to compare the microorganisms in meibomian gland secretions from patients with internal hordeolum before an ...

作者: Lijun Tang  1, Xiao Zhao  2, Shitong Li  2, Lina Huang  2, Jinbao Li  2, Lianhua Chen  1, Shiwei Huang  2 (Affiliations 1 Department of Anesthesiology, Shanghai General Hospital of Nanjing Medical University, Shanghai, China. 2 Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China.)

出处: Frontiers in medicine 2022 Vol.9 P717477

关键词: apnea duration;oxygen saturation;rapid sequence induction intubation;rocuronium;succinylcholine.

摘要: Objective: The present study aimed to evaluate the impact of 1.5 mg/kg succinylcholine or 1.2 mg/kg rocuronium, vs. 1.0 mg/kg succinylcholine on apnea ...

作者: Tang, Gang1;Du, Yi1;Guan, Haochen1;Jia, Jieshuang1;Zhu, Nan1;Shi, Yuping1;Rong, Shu1;Yuan, Weijie1 (1 Department of Nephrology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China)

出处: British Journal of Pharmacology 2022 Vol.179 No.1 P159-178

关键词: butyrate;db/db mice;diabetic nephropathy;FFA2;muscle atrophy

摘要: Background and Purpose: Muscle protein catabolism in patients with diabetic nephropathy (DN) results in striking loss of muscle proteins, which increa ...

作者: Dong Lin  1, Liang Wu  1, Jiang Fan  1 (Affiliation 1 Department of Thoracic Surgery, Shanghai General Hospital Shanghai Jiao Tong University School of Medicine, Shanghai, China.)

出处: JAMA surgery 2022

作者: Yingying Sun  1, Jie Jin  2, Aying Zhu  1, Hong Hu  1, Yingying Lu  1, Yue Zeng  1, Dadao Jing  1 (Affiliations 1 Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201600, People\'s Republic of China. 2 Department of Geriatrics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, People\'s Republic of China.)

出处: International journal of general medicine 2022 Vol.15 P1319-1328

关键词: first episode pancreatitis;infected pancreatic necrosis;low-density lipoprotein cholesterol;recurrent acute pancreatitis;risk factors.

摘要: Background: In recent years, the cure rate of acute pancreatitis (AP) has increased gradually, but the morbidity of recurrent acute pancreatitis (RAP) ...

作者: Xiao Shen  1   2, Guorong Fan  1, Gaolin Liu  1, Fan Wang  3, Qi Li  3, Xinyan Liu  2, Hong Zhu  2, Ying Zhu  2, Jiguang Lu  2, Shuowen Wang  1 (Affiliations 1 Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai. 2 Department of Pharmacy, Suzhou Kowloon Hospital, Shanghai Jiaotong University School of Medicine, Suzhou, Jiangsu Province. 3 Department of Oncology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China.)

出处: Anti-cancer drugs 2022 Vol.33 No.1 Pe802-e807

摘要: The incidence of lung cancer is increasing yearly worldwide, and targeted medicines are the main choice for lung cancer patients. However, there has b ...

作者: Weijun Shen1;Xuan Zhao2;Shitong Li1,3CA1 (1 Nanjing Medical University, Shanghai General Hospital, 200080, Shanghai, China; 2 Department of Anesthesiology, Tenth People’s Hospital of Tongji University, No 301 Middle Yan Chang Road, 200072, Shanghai, China; 3 Nanjing Medical University, Shanghai General Hospital, 200080, Shanghai, China)

出处: Inflammation 2022 Vol.45 No.1 P331-342

关键词: exosomes;sepsis;lung injury;circ-fryl;SIRT3.

摘要: Sepsis-induced lung injury is a clinical syndrome characterized by injury of alveolar epithelium cells (AECs). Previous investigations illustrate that ...

作者: Yongyi Xie #  1, Baoyi Liu #  1, Zhouwei Wu  1 (Affiliation 1 Department of Dermatology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, People\'s Republic of China.)

出处: Clinical, cosmetic and investigational dermatology 2022 Vol.15 P77-86

关键词: biomarker;metabolism;systemic lupus erythematosus.

摘要: Purpose: Skin involvement is the second most common symptom of systemic lupus erythematosus (SLE), and the prevention of skin lesion development might ...

作者: Xuhui Fan  1, Ni Xie  2, Jingwen Chen  1, Tiewen Li  3, Rong Cao  1, Hongwei Yu  1, Meijuan He  1, Zilin Wang  1, Yihui Wang  1, Hao Liu  4, Han Wang  1   2   5, Xiaorui Yin  1 (Affiliations 1 Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 2 Institution for Clinical Research, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 3 Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 4 Department of Research and Development, Yizhun Medical AI Technology Co. Ltd., Beijing, China. 5 Department of Radiology, Jiading Branch of Shanghai General Hospital, Shanghai, China.)

出处: Frontiers in oncology 2022 Vol.12 P839621

关键词: biological characteristics;magnetic resonance imaging;prostate cancer;radiomics;risk stratification.

摘要: Objectives: This study aims to develop and evaluate multiparametric MRI (MP-MRI)-based radiomic models as a noninvasive diagnostic method to predict s ...

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