作者： Dong, ZX (Dong, Zhixia);Su, L (Su, Lin);Esmaili, S (Esmaili, Saeed);Iseli, TJ (Iseli, Tristan J.);Ramezani-Moghadam, M (Ramezani-Moghadam, Mehdi);Hu, LS (Hu, Liangshuo);Xu, AM (Xu, Aimin);George, J (George, Jacob);Wang, JH (Wang, Jianhua) （1.Department of Gastroenterology, Shanghai General Hospital,Shanghai Jiaotong University School of Medicine,Shanghai,China;2.Storr Liver Unit, Westmead Millennium Institute and Westmead Hospital,University of Sydney,Westmead,Australia;3.State Key Laboratory of Pharmaceutical Biotechnology, and Department of Medicine,the University of Hong Kong,Hong Kong,Hong Kong）

出处： JOURNAL OF MOLECULAR MEDICINE-JMM 2015 Vol.93 No.12 P1327-1339

关键词： Adiponectin;Hepatic;stellate;cell;Inducible;nitric;oxide;synthase;The;AMP-activated;protein;kinase

摘要： Adiponectin protects against liver fibrosis, but the mechanisms have not been fully elucidated. Here, we showed that adiponectin upregulated inducible ...

作者： Li-Li Wang;Wen-Jia Liu;Hai-Yun Liu;Xun Xu （Department of Ophthalmology, Shanghai First People's Hospital, Shanghai 200080, China）

出处： Chin Med J (Engl) 2015 Vol.128 No.9 P1154-1159

关键词： Chinese Version of National Eye Institute Visual Function Questionnaire-25;Ranibizumab;Vision-related Quality of Life;Wet Age-related Macular Degeneration

摘要： BACKGROUND: Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss among the older population. In China, treatment of ...

作者： Cuiping Fu;Junting Zhang;Ye Zheng;Hongbing Xu;Shaoning Yu （a Department of Chemistry, Fudan University, Shanghai 200433, China b Shanghai Pinghe Bilingual School, China c Department of Clinical Pharmacy, Shanghai First People's Hospital, Shanghai Jiaotong University, Shanghai 200080, China）

出处： Int J Biol Macromol. 2015 Vol.79 P235-239

关键词： KEYWORDS: Calcineurin; Calcineurin regulatory region; Calmodulin; FT-IR spectroscopy; ITC

摘要： Calcineurin (CN) is a Ca(2+)/calmodulin (CaM) activated serine/threonine phosphatase, and its regulatory region (CNRR) plays a critical role in the co ...

作者： Xiaocheng Cheng;Jin Tong;Qiongwen Hu;Shaojie Chen;Yuehui Yin;Zengzhang Liu （a Department of Cardiology, The Second Affiliated Hospital/The Second Clinical Institute, Chongqing Medical University, Chongqing, China b Department of Respirology, The Second Affiliated Hospital/The Second Clinical Institute, Chongqing Medical University, Chongqing, China c Department of Clinical Laboratory, The Third People's Hospital of Chongqing, Chongqing, China d Cardiology/Medicine, Shanghai First People’s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China）

出处： European Journal of Cardio-Thoracic Surgery 2015 Vol.47 No.6 P958-966

关键词： RASI;Cardiac surgery;CABG;Mortality;Meta-analysis

摘要： The purpose of this meta-analysis was to assess the role of preoperative renin-angiotensin system inhibitor (RASI) therapy on major adverse cardiac ev ...

作者： Wuping Bao;Ping Liu;Zhongmin Qiu;Li Yu;Jingqing Hang;Xiaohua Gao;Xin Zhou （1 Department of Respiratory Medicine, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai 200080, China 2 Department of Respiratory Medicine, Tongji Hospital, Tongji University, School of Medicine, Shanghai 200065, China 3 Department of Respiratory Medicine, Shanghai Putuo People's Hospital, Shanghai 200060, China 4 Department of Respiratory Medicine, Qingdao Sanatorium Medical Center of Shandong Province, Qingdao, Shandong 266071, China）

出处： Chin Med J (Engl) 2015 Vol.128 No.1 P39-45

关键词： Budesonide;Cough;Quality of Life;Montelukast;Bronchitis

摘要： BACKGROUND: The efficacy of montelukast (MONT), a cysteinyl leukotriene receptor antagonist, in nonasthmatic eosinophilic bronchitis (NAEB), especiall ...

作者： Jian Chen;Huijun Lu;Dongwang Yan;Feifei Cui;Xiaoliang Wang;Fudong Yu;Yingming Xue;Xiaodong Feng;Jingtao Wang;Xiao Wang;Tao Jiang;Meng Zhang;Senlin Zhao;Yang Yu;Huamei Tang;Zhihai Peng （1 Department of General Surgery, Shanghai First People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People's Republic of China 2 Department of Pathology, Shanghai First People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People's Republic of China 3 Basic Medical College, Taishan Medical University, Tai'an, People's Republic of China 4 Department of Anal-Colorectal Surgery, General Hospital of Ningxia Medical University, Yinchuan, People‘s Republic of China）

出处： Oncotarget 2015 Vol.6 No.1 P355–367

关键词： p21-activated kinase 6, Colon cancer, 5-fluorouracil, Chemoresistance

摘要： p21-Activated kinase 6 (PAK6) has been implicated in radiotherapy and docetaxel resistance. We have further evaluated PAK6 as a predictor of 5-fluorou ...

作者： Du, Yiheng;Bi, Wenhuan;Zhang, Fei （1 Department of Urology, Shanghai First People\'s Hospital affiliated to Shanghai Jiao Tong University, Shanghai People\'s Republic of China 2 Department of Urology, Weifang Hospital of Chinese Traditional Medicine, Shandong People\'s Republic of China）

出处： BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY 2015 Vol.62 No.6 P855-860

关键词： G‐protein–coupled receptor 137;G-protein-coupled receptor 137;lentivirus;proliferation;urinary bladder cancer

摘要： Urinary bladder cancer is a worldwide concern because of its level of incidence and recurrence. To search an effective therapeutic strategy for urinar ...

作者： Yuan, Huihua;Li, Kai;Li, Biyun;Lou, Xiangxin;Zhao, Qinghua;Zhang, Yanzhong （1 College of Chemistry, Chemical Engineering & Biotechnology, Donghua University, Shanghai 201620, China 2 Department of Orthopaedic, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, 100 Haining Road, Shanghai 200080, China）

出处： Journal of Controlled Release 2015 Vol.213 Pe43-e44

作者： Zhou, Zhe;Zhang, Ming;Xu, Mingxi;Zhang, Ke;Zhao, Yang;Zhou, Juan;Zhu, Yingjian;Wang, Zhong;Lu, Mujun （1 Department of Urology, Shanghai 9th People\'s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200-011 China 2 Department of Urology, Shanghai 1st People\'s Hospital, Shanghai, Jiaotong University School of Medicine, Shanghai 200-011 China）

出处： Biotechnology & Bioprocess Engineering 2015 Vol.20 No.3 P523-531

关键词： intraperitoneal incubation;regeneration;tissue engineering;urinary bladder

摘要： The objective of this study was to investigate whether intraperitoneal incubation improves the regenerative capacity of bladder acellular matrix graft ...

作者： Zhou, J (Zhou Jing);Yuan, WJ (Yuan Wei-jie);Zhu-Ge, YF (Zhu-ge Yi-feng) （;[ 1 ] Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 1, Dept Nephrol, Shanghai 200080, Peoples R China）

出处： CELLULAR SIGNALLING 2015 Vol.27 No.9 P1772-1780

关键词： Wt1;Wnt/beta-catenin signaling;LRP6;Podocyte dysfunction

摘要： Podocyte dysfunction plays important roles in the pathogenesis of chronic kidney disease, and Wt1 has long been considered to be a marker of podocyte, ...